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Your search keyword '"Gao, Yemei"' showing total 8 results
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8 results on '"Gao, Yemei"'

3. Expert consensus on the clinical application of Xuanfei Baidu granule

Author

Liu, Qingquan, Zhang, Hongchun, Wang, Chengxiang, Miao, Qing, Yang, Fengwen, Huang, Yuhong, Zheng, Wenke, Feng, Jihong, Zhang, Li, Su, Rui, Ding, Banghan, Sun, Gengyun, Zhang, Huiyong, Cui, Hongsheng, Lin, Dianjie, Li, Suyun, Chen, Zhuochang, Liu, Hua, Geng, Limei, Zhu, Zhengang, Zhang, Lingzhi, Dai, Luming, Tian, Yingchun, Yang, Jie, Yang, Lijun, Hu, Weidong, Zhao, Yunxia, Liu, Shuang, Xue, Bing, Nie, Xiuhong, Xue, Xiaoming, Wang, Huaili, Pan, Lei, Chen, Qianhua, Zhou, Xianmei, Zhang, Zhongde, Sun, Jie, Zhang, Wei, Tang, Huaping, Zhang, Wei, Wang, Daoxin, You, Baiwen, Yang, Shuanying, Pan, Pinhua, Ma, Zhanping, Fu, Dahai, Sun, Lianqing, Huang, Yong, Yang, Guohan, Ren, Yi, Wu, Bin, He, Yong, Xu, Fei, Xiao, Zuke, Yang, Yi, Huang, Jiehui, Fang, Tianshu, Wang, Yejian, Liang, Wenjian, Li, Qiuxia, Bai, Guihong, He, Xiaopeng, Wang, Hongjian, Zhang, Nianzhi, Li, Zhuying, Li, Qunying, Qu, Nini, Ge, Zhengxing, Xin, Xiaoyi, Zhu, Yulong, Liu, Xiangqun, Sui, Jing, Liu, Yun, Yang, Yang, Chen, Lijun, Bao, Hong, Zheng, Xiao, Gao, Yemei, and Gong, Xianfeng

Published
2023
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7. Chemotherapy-induced amenorrhea and its effects on fertility in long-term female survivors of classic osteosarcoma

Author

Jiang Yang, Gao Yemei, Niu Xiao-hui, Xu Hairong, and Huang Zhen

Subjects
musculoskeletal diseases, medicine.medical_specialty, media_common.quotation_subject, medicine.medical_treatment, Fertility, Antineoplastic Agents, Bone Neoplasms, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, 030212 general & internal medicine, Fertility preservation, Survivors, Marriage, Child, Amenorrhea, media_common, Aged, Retrospective Studies, Chemotherapy, Osteosarcoma, Obstetrics, business.industry, Incidence (epidemiology), Retrospective cohort study, medicine.disease, Oncology, 030220 oncology & carcinogenesis, Marital status, Female, medicine.symptom, business
Abstract

To explore the effect of chemotherapy-induced amenorrhea (CIA) on female osteosarcoma patients’ fertility function, we investigated and analyzed their marital status, fertility, and menstrual status in a retrospective cohort study. We selected female osteosarcoma patients from database from January 2004 to December 2013. Patients’ characteristics such as age, tumor location, marital status, menstrual status, and fertility status were collected. The data were analyzed using the Statistical Package for the Social Sciences (SPSS), version 22. A total of 122 female patients met these criteria and finally responded by questionnaire and telephone follow-up. The marriage rate of female osteosarcoma survivors was 50.8% (62/122), which was significantly lower than the control group (p = 0.000). The average marriage age of female osteosarcoma survivors was 25.5, which was obviously higher than the control group (p = 0.000). CIA occurred in 46 (36.1%) patients. We then found that the incidence of CIA was higher in older patients. (p = 0.011). All of the married patients wanted to have children, and 67.8% (42/62) of them had given birth after chemotherapy. The fertility of married patients with CIA was significantly reduced compared to that of married patients without CIA. (p = 0.001). The patients with CIA have higher risk of impaired reproductive function than those who did not. Fertility preservation option before the start of the chemotherapy is important. And it is much value to record menstrual pattern and detect sex steroid levels after 6 months of therapy in order to be able to evaluate the fertility status.

Published
2020

8. [Expression of Ezrin and E-cadherin in nasopharyngeal carcinoma and its significance].

Author

Wang L, Gao Y, Tu Q, and Hong J

Subjects
Adult, Aged, Antigens, CD, Cadherins genetics, Cytoskeletal Proteins genetics, Female, Humans, Immunohistochemistry, Lymphatic Metastasis, Male, Middle Aged, Neoplasm Invasiveness, Prognosis, Young Adult, Cadherins metabolism, Carcinoma, Squamous Cell metabolism, Cytoskeletal Proteins metabolism, Nasopharyngeal Neoplasms metabolism
Abstract

Objective: To explore the association of Ezrin and E-cadherin expression with the invasion, metastasis and prognois of nasopharyngeal carcinoma., Methods: Imunohistochemical SP staining was used to detect the expression of Ezrin and E-cadherin in 42 nasopharyngeal carcinoma and 10 chronic nasopharyngitis specimens., Results: Ezrin protein expression in the nasopharyngeal carcinoma tissues was significantly higher than that in the chronic nasopharyngitis tissues (P<0.05). E-cadherin expression in the nasopharyngeal carcinoma tissues was significantly lower than that in the chronic nasopharyngitis tissues (P<0.05). Expressions of both Ezrin and E-cadherin of nasopharyngeal carcinoma were closely associated with T staging,the cervical lymph node metastases and clinical staging (P<0.05). A negative correlation was found between Ezrin and E-cadherin expression in the nasopharyngeal carcinoma tissues (r=-0.450, P<0.05). Survival analysis showed that the abnormal expression of Ezrin and E-cadhrin, clinical staging and the cervical lymph node metastases were associated with the survival rate of patients with nasopharyngeal carcinoma., Conclusion: A negative correlation is found between Ezrin and E-cadherin expression in the nasopharyngeal carcinoma tissues. Ezrin and E-cadherin are closely related to clinical staging and the cervical lymph node metastases of nasopharyngeal carcinoma,suggesting that they may be important tumor markers for nasopharyngeal carcinoma. Combined detection of the expressions of Ezrin and E-cadherin is helpful for clinical doctors to determine the prognosis of patients with nasopharyngeal carcinoma.

Published
2010
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