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8. Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilliin vivo andin vitro

Author

Liao Fang, Xu Hanlin, Yang Zhen-de, Huang Qinghua, and Gao Qinhua

Subjects
Male, Bacilli, Biomedical Engineering, Shigella sonnei, Microbial Sensitivity Tests, Biochemistry, Shigella flexneri, Microbiology, Biomaterials, Mice, Minimum inhibitory concentration, In vivo, Oils, Volatile, Genetics, medicine, Animals, Dysentery, Bacillary, Earth-Surface Processes, Minimum bactericidal concentration, biology, Dysentery, Origanum, biology.organism_classification, medicine.disease, digestive system diseases, In vitro, Anti-Bacterial Agents, bacteria, Female, Bacteria
Abstract

To observe the germistatic and germicidal effects of origanum volatile oil (OVI) on the dysentery bacteria, the abdominal cavity of mice was infected with Shigella sonne (Sh. sonnei) and Shigella flexneri (Sh. flexneri) F2a. After OVI was given to the mice via gastric lavage, the effects of OVI on the infected mice were observed. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for dysentery bacteria were determined in vitro. The results showed that origanum volatile oil showed obvious protective effect on mice infected with Sh. sonnei and Sh. flexneri F2a and it had germistatic and germicidal effects on dysentry bacteria. We are led to conclude that origanum volatile oil is an effective medicine against the infection of dysentery bacteria.

Published
2004

9. Experimental study on the antibacterial effect of origanum volatile oil on dysentery bacilli in vivo and in vitro.

Author

Liao F, Huang Q, Yang Z, Xu H, and Gao Q

Subjects
Animals, Female, Male, Mice, Microbial Sensitivity Tests, Shigella flexneri isolation & purification, Shigella sonnei isolation & purification, Anti-Bacterial Agents pharmacology, Dysentery, Bacillary microbiology, Oils, Volatile pharmacology, Shigella flexneri drug effects, Shigella sonnei drug effects
Abstract

To observe the germistatic and germicidal effects of origanum volatile oil (OVI) on the dysentery bacteria, the abdominal cavity of mice was infected with Shigella sonne (Sh. sonnei) and Shigella flexneri (Sh. flexneri) F2a. After OVI was given to the mice via gastric lavage, the effects of OVI on the infected mice were observed. The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) for dysentery bacteria were determined in vitro. The results showed that origanum volatile oil showed obvious protective effect on mice infected with Sh. sonnei and Sh. flexneri F2a and it had germistatic and germicidal effects on dysentry bacteria. We are led to conclude that origanum volatile oil is an effective medicine against the infection of dysentery bacteria.

Published
2004
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