Search

Your search keyword '"Ganzetti, G."' showing total 250 results
Start Over Author "Ganzetti, G."
250 results on '"Ganzetti, G."'

1. Role of mesenchymal stem cells in the pathogenesis of psoriasis: current perspectives

Author

Campanati A, Consales V, Orciani M, Giuliodori K, Ganzetti G, Bobyr I, Sorgentoni G, di Primio R, and Offidani A

Subjects
mesenchymal stem cells, pathogenesis of psoriasis, review, Dermatology, RL1-803
Abstract

Anna Campanati*, Veronica Consales*, Monia Orciani, Katia Giuliodori, Giulia Ganzetti, Ivan Bobyr, Giulia Sorgentoni, Roberto di Primio, Annamaria Offidani Dermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, Ancona, Italy *These authors contributed equally to this work Abstract: Mesenchymal stem cells (MSCs) are multipotent nonhematopoietic stromal cells studied for their properties and importance in management of several skin diseases. This review collects and analyzes the emerging published data, which describe the function of MSCs in the pathogenesis of psoriasis. Keywords: mesenchymal stem cells, pathogenesis of psoriasis, review

Published
2017

3. Diagnosis and management of cutaneous and anogenital lichen sclerosus: Recommendations from the Italian Society of Dermatology (SIDemaSt)

Author

Papini, M, Russo, A, Simonetti, O, Borghi, A, Corazza, M, Piaserico, S, Feliciani, C, Calzavara-Pinton, P, Amendolagine, G, Arisi, M, Babino, G, Bardazzi, F, Belloni Fortina, A, Cac-Cavale, S, Campanati, A, Campione, E, Caposiena, C, Carugno, A, Coati, I, Cinotti, E, D'Antuono, A, Dattola, A, Dika, E, Fai, D, Fusano, M, Galluzzo, M, Ganzetti, G, Gisondi, P, Hansel, K, Lora, V, Maione, V, Mandel, V, Menni, S, Negosanti, M, Neri, I, Offidani, A, Parodi, A, Patrizi, A, Peserico, A, Rossi, M, Rivetti, N, Saccani, E, Stan, T, Stingeni, L, Talamonti, M, Vascellaro, A, Vezzoli, P, Virgili, A, Zanca, A, Papini M., Russo A., Simonetti O., Borghi A., Corazza M., Piaserico S., Feliciani C., Calzavara-Pinton P., Amendolagine G., Arisi M., Babino G., Bardazzi F., Belloni Fortina A., Cac-Cavale S., Campanati A., Campione E., Caposiena C. D., Carugno A., Coati I., Cinotti E., D'Antuono A., Dattola A., Dika E., Fai D., Fusano M., Galluzzo M., Ganzetti G., Gisondi P., Hansel K., Lora V., Maione V., Mandel V. D., Menni S., Negosanti M., Neri I., Offidani A., Parodi A., Patrizi A., Peserico A., Rossi M., Rivetti N., Saccani E., Stan T. R., Stingeni L., Talamonti M., Vascellaro A., Vezzoli P., Virgili A., Zanca A., Papini, M, Russo, A, Simonetti, O, Borghi, A, Corazza, M, Piaserico, S, Feliciani, C, Calzavara-Pinton, P, Amendolagine, G, Arisi, M, Babino, G, Bardazzi, F, Belloni Fortina, A, Cac-Cavale, S, Campanati, A, Campione, E, Caposiena, C, Carugno, A, Coati, I, Cinotti, E, D'Antuono, A, Dattola, A, Dika, E, Fai, D, Fusano, M, Galluzzo, M, Ganzetti, G, Gisondi, P, Hansel, K, Lora, V, Maione, V, Mandel, V, Menni, S, Negosanti, M, Neri, I, Offidani, A, Parodi, A, Patrizi, A, Peserico, A, Rossi, M, Rivetti, N, Saccani, E, Stan, T, Stingeni, L, Talamonti, M, Vascellaro, A, Vezzoli, P, Virgili, A, Zanca, A, Papini M., Russo A., Simonetti O., Borghi A., Corazza M., Piaserico S., Feliciani C., Calzavara-Pinton P., Amendolagine G., Arisi M., Babino G., Bardazzi F., Belloni Fortina A., Cac-Cavale S., Campanati A., Campione E., Caposiena C. D., Carugno A., Coati I., Cinotti E., D'Antuono A., Dattola A., Dika E., Fai D., Fusano M., Galluzzo M., Ganzetti G., Gisondi P., Hansel K., Lora V., Maione V., Mandel V. D., Menni S., Negosanti M., Neri I., Offidani A., Parodi A., Patrizi A., Peserico A., Rossi M., Rivetti N., Saccani E., Stan T. R., Stingeni L., Talamonti M., Vascellaro A., Vezzoli P., Virgili A., and Zanca A.

Abstract

Lichen sclerosus (LS) is a disabling chronic inflammatory disease of skin and genital mucous membrane causing itch, pain, dysuria and restriction of micturition, and significant sexual dysfunction and dyspareunia both in women and men. If left untreated, LS is associated with a high degree of sclerosis and scarring, as well as with an elevated risk of cancer in the genital area. Although a central role of autoimmunity is suggested, the pathogenesis of LS is still not clearly understood and the disease remains difficult to treat. The goals of treatment of LS are to alleviate symptoms and discomfort, prevent anatomical changes and prevent malignant transformation. this guideline has been developed by an Italian group of experts. It summarizes evidence-based and expert- based recommendations. The highest level of evidence favors the use of topical high potency corticosteroids; second- and third-line treatments include topical calcineurin inhibitors and topical retinoids, respectively. Surgical treatment has become the treatment of choice in male genital LS with persistent phimosis not responsive to medical treatment. The aim of this paper is to offer evidence-based and easily applicable recommendations for the management of lS.

Published
2021

5. Diagnosis and management of cutaneous and anogenital lichen sclerosus: Recommendations from the Italian Society of Dermatology (SIDemaSt)

Author

Papini, M., Russo, A., Simonetti, O., Borghi, A., Corazza, M., Piaserico, S., Feliciani, C., Calzavara-Pinton, P., Amendolagine, G., Arisi, M., Babino, G., Bardazzi, F., Belloni Fortina, A., Cac-Cavale, S., Campanati, A., Campione, E., Caposiena, C. D., Carugno, A., Coati, I., Cinotti, E., D'Antuono, A., Dattola, A., Dika, E., Fai, D., Fusano, M., Galluzzo, M., Ganzetti, G., Gisondi, P., Hansel, K., Lora, V., Maione, V., Mandel, V. D., Menni, S., Negosanti, M., Neri, I., Offidani, A., Parodi, A., Patrizi, A., Peserico, A., Rossi, M., Rivetti, N., Saccani, E., Stan, T. R., Stingeni, L., Talamonti, M., Vascellaro, A., Vezzoli, P., Virgili, A., Zanca, A., Papini, M., Russo, A., Simonetti, O., Borghi, A., Corazza, M., Piaserico, S., Feliciani, C., Calzavara-Pinton, P., Amendolagine, G., Arisi, M., Babino, G., Bardazzi, F., Belloni Fortina, A., Caccavale, S., Campanati, A., Campione, E., Caposiena, C. D., Carugno, A., Coati, I., Cinotti, E., D'Antuono, A., Dattola, A., Dika, E., Fai, D., Fusano, M., Galluzzo, M., Ganzetti, G., Gisondi, P., Hansel, K., Lora, V., Maione, V., Mandel, V. D., Menni, S., Negosanti, M., Neri, I., Offidani, A., Parodi, A., Patrizi, A., Peserico, A., Rossi, M., Rivetti, N., Saccani, E., Stan, T. R., Stingeni, L., Talamonti, M., Vascellaro, A., Vezzoli, P., Virgili, A., Zanca, A., Papini, M, Russo, A, Simonetti, O, Borghi, A, Corazza, M, Piaserico, S, Feliciani, C, Calzavara-Pinton, P, Amendolagine, G, Arisi, M, Babino, G, Bardazzi, F, Belloni Fortina, A, Cac-Cavale, S, Campanati, A, Campione, E, Caposiena, C, Carugno, A, Coati, I, Cinotti, E, D'Antuono, A, Dattola, A, Dika, E, Fai, D, Fusano, M, Galluzzo, M, Ganzetti, G, Gisondi, P, Hansel, K, Lora, V, Maione, V, Mandel, V, Menni, S, Negosanti, M, Neri, I, Offidani, A, Parodi, A, Patrizi, A, Peserico, A, Rossi, M, Rivetti, N, Saccani, E, Stan, T, Stingeni, L, Talamonti, M, Vascellaro, A, Vezzoli, P, Virgili, A, Zanca, A, Papini M., Russo A., Simonetti O., Borghi A., Corazza M., Piaserico S., Feliciani C., Calzavara-Pinton P., Amendolagine G., Arisi M., Babino G., Bardazzi F., Belloni Fortina A., Cac-Cavale S., Campanati A., Campione E., Caposiena C.D., Carugno A., Coati I., Cinotti E., D'Antuono A., Dattola A., Dika E., Fai D., Fusano M., Galluzzo M., Ganzetti G., Gisondi P., Hansel K., Lora V., Maione V., Mandel V.D., Menni S., Negosanti M., Neri I., Offidani A., Parodi A., Patrizi A., Peserico A., Rossi M., Rivetti N., Saccani E., Stan T.R., Stingeni L., Talamonti M., Vascellaro A., Vezzoli P., Virgili A., and Zanca A.

Subjects
Male, medicine.medical_specialty, Calcineurin Inhibitors, Socio-culturale, Disease, Dermatology, Lichen sclerosus, Guideline, Settore MED/35, Lichen sclerosus et atrophicu, medicine, Dysuria, Humans, Sex organ, Drug therapy, Lichen sclerosus et atrophicus, Operative surgical procedures, Rare diseases, Vulvar lichen sclerosus, Female, Italy, Mometasone Furoate, Lichen Sclerosus et Atrophicus, Calcineurin Inhibitor, business.industry, Mucous membrane, Evidence-based medicine, medicine.disease, Infectious Diseases, medicine.anatomical_structure, Sexual dysfunction, Operative surgical procedure, Vulvar lichen sclerosu, medicine.symptom, business, Rare disease, Human
Abstract

Lichen sclerosus (LS) is a disabling chronic inflammatory disease of skin and genital mucous membrane causing itch, pain, dysuria and restriction of micturition, and significant sexual dysfunction and dyspareunia both in women and men. If left untreated, LS is associated with a high degree of sclerosis and scarring, as well as with an elevated risk of cancer in the genital area. Although a central role of autoimmunity is suggested, the pathogenesis of LS is still not clearly understood and the disease remains difficult to treat. The goals of treatment of LS are to alleviate symptoms and discomfort, prevent anatomical changes and prevent malignant transformation. This guideline has been developed by an Italian group of experts. It summarizes evidence-based and expert- based recommendations. The highest level of evidence favors the use of topical high potency corticosteroids; second- and third-line treatments include topical calcineurin inhibitors and topical retinoids, respectively. Surgical treatment has become the treatment of choice in male genital LS with persistent phimosis not responsive to medical treatment. The aim of this paper is to offer evidence-based and easily applicable recommendations for the management of LS.

Published
2021

9. Myocardial overexpression of ANKRD1 causes sinus venosus defects and progressive diastolic dysfunction

Author

Piroddi, N, Pesce, P, Scellini, B, Manzini, S, Ganzetti, G, Badi, I, Menegollo, M, Cora, V, Tiso, S, Cinquetti, R, Monti, L, Chiesa, G, Bleyl, S, Busnelli, M, Dellera, F, Bruno, D, Caicci, F, Grimaldi, A, Taramelli, R, Manni, L, Sacerdoti, D, Tesi, C, Poggesi, C, Ausoni, S, Acquati, F, Campione, M, Piroddi N., Pesce P., Scellini B., Manzini S., Ganzetti G. S., Badi I., Menegollo M., Cora V., Tiso S., Cinquetti R., Monti L., Chiesa G., Bleyl S. B., Busnelli M., Dellera F., Bruno D., Caicci F., Grimaldi A., Taramelli R., Manni L., Sacerdoti D., Tesi C., Poggesi C., Ausoni S., Acquati F., Campione M., Piroddi, N, Pesce, P, Scellini, B, Manzini, S, Ganzetti, G, Badi, I, Menegollo, M, Cora, V, Tiso, S, Cinquetti, R, Monti, L, Chiesa, G, Bleyl, S, Busnelli, M, Dellera, F, Bruno, D, Caicci, F, Grimaldi, A, Taramelli, R, Manni, L, Sacerdoti, D, Tesi, C, Poggesi, C, Ausoni, S, Acquati, F, Campione, M, Piroddi N., Pesce P., Scellini B., Manzini S., Ganzetti G. S., Badi I., Menegollo M., Cora V., Tiso S., Cinquetti R., Monti L., Chiesa G., Bleyl S. B., Busnelli M., Dellera F., Bruno D., Caicci F., Grimaldi A., Taramelli R., Manni L., Sacerdoti D., Tesi C., Poggesi C., Ausoni S., Acquati F., and Campione M.

Abstract

Aims Increased Ankyrin Repeat Domain 1 (ANKRD1) levels linked to gain of function mutations have been associated to total anomalous pulmonary venous return and adult cardiomyopathy occurrence in humans. The link between increased ANKRD1 level and cardiac structural and functional disease is not understood. To get insight into this problem, we have generated a gain of function ANKRD1 mouse model by overexpressing ANKRD1 in the myocardium.Methods and results Ankrd1 is expressed non-homogeneously in the embryonic myocardium, with a dynamic nucleo-sarcomeric localization in developing cardiomyocytes. ANKRD1 transgenic mice present sinus venosus defect, which originates during development by impaired remodelling of early embryonic heart. Adult transgenic hearts develop diastolic dysfunction with preserved ejection fraction, which progressively evolves into heart failure, as shown histologically and haemodynamically. Transgenic cardiomyocyte structure, sarcomeric assembly, and stability are progressively impaired from embryonic to adult life. Postnatal transgenic myofibrils also present characteristic functional alterations: impaired compliance at neonatal stage and impaired lusitropism in adult hearts. Altogether, our combined analyses suggest that impaired embryonic remodelling and adult heart dysfunction in ANKRD1 transgenic mice present a common ground of initial cardiomyocyte defects, which are exacerbated postnatally. Molecular analysis showed transient activation of GATA4-Nkx2.5 transcription in early transgenic embryos and subsequent dynamic transcriptional modulation within titin gene.Conclusions ANKRD1 is a fine mediator of cardiomyocyte response to haemodynamic load in the developing and adult heart. Increased ANKRD1 levels are sufficient to initiate an altered cellular phenotype, which is progressively exacerbated into a pathological organ response by the high ventricular workload during postnatal life. Our study defines for the first time a unifying picture f

Published
2020

21. Serum and tissue CTACK/CCL27 chemokine levels in early mycosis fungoides may be correlated with disease-free survival following treatment with interferon alfa and psoralen plus ultraviolet A therapy

Author

Goteri, G., Rupoli, S., Campanati, A., Zizzi, A., Picardi, P., Cardelli, M., Giantomassi, F., Canafoglia, L., Marchegiani, F., Mozzicafreddo, G., Brandozzi, G., Stramazzotti, D., Ganzetti, G., Lisa, R., Simonetti, O., Offidani, A., Federici, I., Filosa, G., and Leoni, P.

Published
2012
Full Text
View/download PDF

28. Italian guidelines in pemphigus - adapted from the European Dermatology Forum (EDF) and European Academy of Dermatology and Venerology (EADV)

Author

Feliciani C, Cozzani E, Marzano AV, Caproni M, Di Zenzo G, Calzavara-Pinton P, 'Cutaneous Immunology\\' group of SIDeMaST (Alaibac M, Antiga E, Arisi M, Assalve D, Atzori L, Babino G, Balato A, Balato N, Barbagallo T, Belloni Fortina A, Berardesca E, Berti E, Borghi A, Brazzelli V, Brumana MB, Brusati C, Caccavale S, Caldarola G, Campanati A, Caposiena Caro RD, Coati I, Conti A, Costanzo A, Dattola A, De Simone C, Di Cesare A, Di Lernia V, Di Zenzo GM, Fania L, Filosa G, Filotico R, Fusano M, Gerarda Galluccio A, Ganzetti G, Gisondi P, Guarneri F, Hansel K, Javor S, La Placa M, Liberati G, Lora V, Merlo G, Nasca MR, Nigro A, Noal C, Offidani A, Papini M, Parodi A, Patrizi A, Peserico A, Piaserico S, Prignano F, Quaglino P, Rossi M, Satta R, Schena D, Sena P, Simonetti O, Stan TR, Stingeni L, Talamonti M, Tavecchio S, Tognetti L, Vascellaro A, Vassallo C, Venturini M, Zampetti A, Zanca A)., Feliciani, Claudio, Cozzani, Emanuele, Marzano, Angelo V., Caproni, Marzia, Di Zenzo, Giovanni, Calzavara-Pinton, Piergiacomo, La placa M, Patrizi a, Feliciani, C, Cozzani, E, Marzano, Av, Caproni, M, Di Zenzo, G, Calzavara-Pinton, P, 'Cutaneous Immunology' group of SIDeMaST (Alaibac, M, Antiga, E, Arisi, M, Assalve, D, Atzori, L, Babino, G, Balato, A, Balato, N, Barbagallo, T, Belloni Fortina, A, Berardesca, E, Berti, E, Borghi, A, Brazzelli, V, Brumana, Mb, Brusati, C, Caccavale, S, Caldarola, G, Campanati, A, Caposiena Caro, Rd, Coati, I, Conti, A, Costanzo, A, Dattola, A, De Simone, C, Di Cesare, A, Di Lernia, V, Di Zenzo, Gm, Fania, L, Filosa, G, Filotico, R, Fusano, M, Gerarda Galluccio, A, Ganzetti, G, Gisondi, P, Guarneri, F, Hansel, K, Javor, S, La Placa, M, Liberati, G, Lora, V, Merlo, G, Nasca, Mr, Nigro, A, Noal, C, Offidani, A, Papini, M, Parodi, A, Patrizi, A, Peserico, A, Piaserico, S, Prignano, F, Quaglino, P, Rossi, M, Satta, R, Schena, D, Sena, P, Simonetti, O, Stan, Tr, Stingeni, L, Talamonti, M, Tavecchio, S, Tognetti, L, Vascellaro, A, Vassallo, C, Venturini, M, Zampetti, A, and Zanca, A).

Subjects
Male, medicine.medical_specialty, Venereology, Pemphigus - Guidelines - Skin diseases, Vesiculobullous, Autoantibodies, Evidence-Based Medicine, Female, Humans, Italy, Pemphigus, Skin, Socio-culturale, Dermatology, Desmoglein, Pemphigu, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Settore MED/35, Medicine, Skin pathology, skin and connective tissue diseases, Vesiculobullou, integumentary system, business.industry, Guideline, Evidence-based medicine, medicine.disease, Autoantibodie, 2708, 030220 oncology & carcinogenesis, Pemphigus - Guidelines - Skin disease, business, Blistering disease, Human
Abstract

Pemphigus is a life threatening autoimmune epidermal blistering disease involving skin and mucous membranes. Pemphigus usually affects middle age men and women involving oral mucosa first and then spreading on the skin. It is caused by the presence of autoantibodies (IgG and less frequently by IgA) directed against desmogleins, and/or other glycoproteins that plays a critical role in cell-cell attachment. Upon a predisposing genetic background, different agents have been shown to act as triggers for the pathogenesis of pemphigus. This guideline for the diagnosis and treatment of pemphigus has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum in collaboration with the European Academy of Dermatology and Venereology. It summarizes evidence-based and expert-based recommendations (S2 level).

Published
2018

29. Bullous pemphigoid: Italian guidelines adapted from the EDF/EADV guidelines

Author

Cozzani, Emanuele, Marzano, Angelo V, Caproni, Marzia, Feliciani, Claudio, Calzavara-Pinton, Piergiacomo, Alaibac, M, Antiga, E, Arisi, M, Assalve, D, Atzori, L, Babino, G, Balato, A, Balato, N, Barbagallo, T, Belloni Fortina, A, Berardesca, E, Berti, E, Borghi, A, Brazzelli, V, Brumana, Mb, Brusati, C, Caccavale, S, Caldarola, G, Calzavara-Pinton, P, Campanati, A, Caposiena Caro RD, Caproni, M, Coati, I, Conti, A, Costanzo, A, Cozzani, E, Dattola, A, De Simone, C, Di Cesare, A, Di Lernia, V, Di Zenzo GM, Fania, L, Filosa, G, Filotico, R, Fusano, M, Gerarda Galluccio, A, Ganzetti, G, Gisondi, P, Guarneri, F, Hansel, K, Javor, S, La Placa, M, Liberati, G, Lora, V, Marzano, Av, Merlo, G, Nasca, Mr, Nigro, A, Noal, C, Offidani, A, Papini, M, Parodi, A, Patrizi, A, Peserico, A, Piaserico, S, Prignano, F, Quaglino, P, Rossi, M, Satta, R, Schena, D, Sena, P, Simonetti, O, Stan, Tr, Stingeni, L, Talamonti, M, Tavecchio, S, Tognetti, L, Vascellaro, A, Vassallo, C, Venturini, M, Zampetti, A, Zanca, A., Cozzani, Emanuele, Marzano, Angelo V., Caproni, Marzia, Feliciani, Claudio, Calzavara-Pinton, Piergiacomo, Alaibac, Mauro, Antiga, Emiliano, Arisi, Mariachiara, Assalve, Danilo, Atzori, Laura, Babino, Graziella, Balato, Anna, Balato, Nicola, Barbagallo, Tania, Fortina, Anna Belloni, Berardesca, Enzo, Berti, Emilio, Borghi, Alessandro, Brazzelli, Valeria, Brumana, Marta B., Brusati, Carlo, Caccavale, Stefano, Caldarola, Giacomo, Campanati, Anna, Caro, Raffaele D. Caposiena, Coati, Ilaria, Conti, Andrea, Costanzo, Antonio, Dattola, Annunziata, De Simone, Clara, Di Cesare, Antonella, Di Lernia, Vito, Di Zenzo, Giovanni M., Fania, Luca, Filosa, Giorgio, Filotico, Raffaele, Fusano, Marta, Galluccio, Antonia Gerarda, Ganzetti, Giulia, Gisondi, Paolo, Guarneri, Fabrizio, Hansel, Katharina, Javor, Sanja, Laplaca, Michelangelo, Liberati, Giulia, Lora, Viviana, Merlo, Giulia, Nasca, Maria R., Nigro, Anna, Noal, Cecilia, Offidani, Annamaria, Papini, Manuela, Parodi, Aurora, Patrizi, Annalisa, Peserico, Andrea, Piaserico, Stefano, Prignano, Francesca, Quaglino, Pietro, Rossi, Mariateresa, Satta, Rosanna, Schena, Donatella, Sena, Paolo, Simonetti, Oriana, Stan, Teodora R., Stingeni, Luca, Talamonti, Marina, Tavecchio, Simona, Tognetti, Linda, Vascellaro, Annalisa, Vassallo, Camilla, Venturini, Marina, Zampetti, Anna, Zanca, Arianna, and La placa, Michelangelo

Subjects
Pemphigoid, Disease, Guideline, 030207 dermatology & venereal diseases, Pruritu, 0302 clinical medicine, Quality of life, Pemphigoid, Bullous, skin and connective tissue diseases, Evidence-Based Medicine, integumentary system, Bullous, Rare diseases, Bullous lesions, Infectious Diseases, Italy, 030220 oncology & carcinogenesis, Practice Guidelines as Topic, Bullou, Bullous pemphigoid, Human, medicine.medical_specialty, Venereology, Consensus, Socio-culturale, Consensu, Dermatology, Aged, Humans, Pruritus, Quality of Life, 2708, 03 medical and health sciences, Pemphigoid, Bullou, Settore MED/35, medicine, business.industry, Evidence-based medicine, medicine.disease, eye diseases, business, Rare disease
Abstract

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).

Published
2018

31. Sex‐related differences of clinical features in hidradenitis suppurativa: analysis of an Italian‐based cohort

Author

Bianchi, L., primary, Caposiena Caro, R. D., additional, Ganzetti, G., additional, Molinelli, E., additional, Dini, V., additional, Oranges, T., additional, Romanelli, M., additional, Fabbrocini, G., additional, Monfrecola, G., additional, Napolitano, M., additional, Egan, C. G., additional, Musumeci, M. L., additional, Lacarrubba, F., additional, Micali, G., additional, Passoni, E., additional, Calzavara‐Pinton, P. G., additional, Venturini, M., additional, Zanca, A., additional, and Offidani, A. M., additional

Published
2018
Full Text
View/download PDF

32. Comparison of clinical and ultrasound scores in patients with hidradenitis suppurativa: results from an Italian ultrasound working group

Author

Napolitano, M., primary, Calzavara-Pinton, P.G., additional, Zanca, A., additional, Bianchi, L., additional, Caposiena Caro, R.D., additional, Offidani, A.M., additional, Ganzetti, G., additional, Molinelli, E., additional, Dini, V., additional, Oranges, T., additional, Romanelli, M., additional, Egan, C.G., additional, Fabbrocini, G., additional, Monfrecola, G., additional, Lacarrubba, F., additional, Musumeci, M.L., additional, Passoni, E., additional, Venturini, M., additional, and Micali, G., additional

Published
2018
Full Text
View/download PDF

33. Supplementary Material for: Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial

Author

Campanati, A., Giannoni, M., Scalise, A., De Blasio, S., Giuliano, A., Giuliodori, K., Ganzetti, G., Bolletta, E., Di Benedetto, G., and Offidani, A.

Abstract

Background/Objective: This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO2 laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. Methods: Efficacy was clinically evaluated by grading the pigmentation level with the Skin Tone Color Scale (STCS), and by grading patients' impression through a Visual Analog Scale (VAS). Results: Our study shows that the associated treatment was safe and that it improves the therapeutic results on solar lentigines and prevents postiatrogenic hyperpigmentation compared with physical therapy alone. Conclusion: The combination of cryotherapy and pidobenzone 4% has been found to be the most useful treatment.

Published
2016
Full Text
View/download PDF

35. Osteopontin: a new facilitating factor in alopecia areata pathogenesis?

Author

Ganzetti, G., Oriana SIMONETTI, Campanati, A., Giuliodori, K., Scocco, V., Brugia, M., Tocchini, M., and Offidani, A.

Subjects
Adult, Cyclopropanes, Male, Young Adult, integumentary system, stomatognathic system, Alopecia Areata, Humans, Female, Osteopontin, Middle Aged, ostepontin, alopecia areata, diphenylciclopropenone, Retrospective Studies
Abstract

Osteopontin (OPN) is a multifunctional glycophosphoprotein secreted by many cell types, including osteoblasts, lymphocites, macrophages, epithelial cells, and vascular smooth muscle cells. It has been implicated in many physiological and pathological processes, such as cell-mediated immunity, inflammation, cell survival, and tumor invasion and metastasis. Osteopontin has multiple emerging roles in cutaneous biology and pathology and OPN involvement has been emphasized in Th1-mediated diseases such as psoriasis. Alopecia areata (AA) is a form of non-scarring hair loss affecting anagen stage hair follicles with a multifactorial autoimmune pathogenesis characterized by a prevalent Th1 cytokine profile. Given the role of osteopontin in Th1-mediated inflammation, we have postulated that OPN may be involved in AA pathogenesis. The aim of our study was to investigate plasma OPN level in alopecia areata before and after DPCP treatment. Our results showed that OPN plasma levels in patients with alopecia areata were higher than in healthy controls, but patients achieving complete recovery after DPCP treatment did not show a statistically significant reduction of OPN plasma levels.

Published
2015

36. Sex‐related differences of clinical features in hidradenitis suppurativa: analysis of an Italian‐based cohort.

Author

Bianchi, L., Caposiena Caro, R. D., Ganzetti, G., Molinelli, E., Dini, V., Oranges, T., Romanelli, M., Fabbrocini, G., Monfrecola, G., Napolitano, M., Egan, C. G., Musumeci, M. L., Lacarrubba, F., Micali, G., Passoni, E., Calzavara‐Pinton, P. G., Venturini, M., Zanca, A., and Offidani, A. M.

Subjects
HIDRADENITIS suppurativa, BUTTOCKS, COHORT analysis, LOGISTIC regression analysis
Abstract

Summary: The clinical characteristics associated with hidradenitis suppurativa (HS) severity are poorly understood. In this study, 124 patients with HS from 6 Italian dermatology centres participated in this study. Disease severity was assessed using the Hidradenitis Suppurativa Physician's Global Assessment score (HS‐PGA) and Hurley score. The impact of clinical characteristics on disease severity was assessed by logistic regression. Clinical characteristics were similar between men (n = 53) and women (n = 71). Disease severity was also similar; 75% of the patients had Hurley stage II or III disease, and > 60% had moderate, severe or very severe HS as judged by HS‐PGA. Lesions were more frequent in the gluteal region in men (32.3% in men vs. 8.7% in women, P < 0.001) and more frequent on the breast in women (16.3% in women vs. 4.6% in men, P = 0.02). Obesity was associated with increased disease severity as measured by HS‐PGA (OR: 3.28, 95% CI 1.55–6.95, P < 0.01) and Hurley classification (OR: 3.22, 95% CI 1.34–7.31, P < 0.01). Although severity of HS is similar between the sexes, the localization of lesions is different. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

39. L-homoarginine administration reduces neointimal hyperplasia in balloon-injured rat carotids

Author

Dellera, F, Ganzetti, G, Froio, A, Manzini, S, Busnelli, M, Meinitzer, A, Sirtori, C, Chiesa, G, Parolini, C, DELLERA, FEDERICA, FROIO, ALBERTO, MANZINI, STEFANO, BUSNELLI, MARCO, Parolini, C., Dellera, F, Ganzetti, G, Froio, A, Manzini, S, Busnelli, M, Meinitzer, A, Sirtori, C, Chiesa, G, Parolini, C, DELLERA, FEDERICA, FROIO, ALBERTO, MANZINI, STEFANO, BUSNELLI, MARCO, and Parolini, C.

Published
2016

40. The effect of low-carbohydrates calorie-restricted diet on visceral adipose tissue and metabolic status in psoriasis patients receiving TNF-alpha inhibitors: results of an open label controlled, prospective, clinical study

Author

Campanati, A., primary, Molinelli, E., additional, Ganzetti, G., additional, Giuliodori, K., additional, Minetti, I., additional, Taus, M., additional, Catani, M., additional, Martina, E., additional, Conocchiari, L., additional, and Offidani, A., additional

Published
2016
Full Text
View/download PDF

42. THU0454 The Multidisciplinary Approach Is The Best Option To Achieve The Improvement of Disease Activity and Quality of Life in Patients Affected by Psoriatic Arthritis: Preliminary Results of A Monocentric Study

Author

Capeci, W., primary, Luchetti, M.M., additional, Campanati, A., additional, Benfaremo, D., additional, Ganzetti, G., additional, Molinelli, E., additional, Rossini, M., additional, Farinelli, A., additional, Ciferri, M., additional, Offidani, A., additional, and Gabrielli, A., additional

Published
2016
Full Text
View/download PDF

43. Comparison of clinical and ultrasound scores in patients with hidradenitis suppurativa: results from an Italian ultrasound working group.

Author

Napolitano, M., Calzavara‐Pinton, P.G., Zanca, A., Bianchi, L., Caposiena Caro, R.D., Offidani, A.M., Ganzetti, G., Molinelli, E., Dini, V., Oranges, T., Romanelli, M., Egan, C.G., Fabbrocini, G., Monfrecola, G., Lacarrubba, F., Musumeci, M.L., Passoni, E., Venturini, M., and Micali, G.

Subjects
HIDRADENITIS suppurativa, TEAMS in the workplace
Abstract

The article offers information on the comparison of clinical and ultrasound scores in patients with hidradenitis suppurativa (HS). Topics discussed include information on the use of the ultrasound techniques for diagnosis and assessment of HS disease severity; discussions on the using sonographic scoring system for HS; and the information on the clinical assessment for the complementary tests.

Published
2019
Full Text
View/download PDF

46. There is a difference of vitamin D receptor gene (VDR) single-nucleotide polymorphisms (SNPs) frequencies between malignant melanoma patients and healthy volunteers and by sex?

Author

Morgese, F., primary, Berardi, R., additional, Pagliaretta, S., additional, Sampaolesi, C., additional, Torniai, M., additional, Campanati, A., additional, Ganzetti, G., additional, Brisigotti, V., additional, Molinelli, E., additional, Ceccarelli, G., additional, Offidani, A., additional, and Cascinu, S., additional

Published
2015
Full Text
View/download PDF

47. The effect of low-carbohydrates calorie-restricted diet on visceral adipose tissue and metabolic status in psoriasis patients receiving TNF-alpha inhibitors: results of an open label controlled, prospective, clinical study.

Author

Campanati, A., Molinelli, E., Ganzetti, G., Giuliodori, K., Minetti, I., Taus, M., Catani, M., Martina, E., Conocchiari, L., and Offidani, A.

Subjects
ADIPOSE tissues, PSORIASIS, CARBOHYDRATES, CALORIE, DIET
Abstract

Objective:TNF alpha inhibitors are usually associated with anthropometric changes over the time, however whether and how the visceral adipose tissue (VAT) is involved in this phenomenon, still remains unclear. Aim of the study is to evaluate if the increases in trunk fat percentage (TF%) and VAT are directly involved in anthropometric changes occurring during treatment, and whether and how a calorie restricted diet could prevent these changes. Material and methods:Twenty patients receiving TNF-alpha inhibitors for psoriasis was evaluated at baseline (T0) and after 24 weeks of therapy (T24), and then compared with 25 patients receiving a combined treatment based on TNF alpha inhibitors and low-carbohydrates calorie-restricted diet. Results:TNF-alpha inhibitors do not influence the VAT expression. The combined treatment is associated with a significant decrease in body weight (kg) (p < .0001), BMI (p = .0001), WC (cm) (p < .0001), TF% (p < .0001), VAT (p < .0001), serum levels of triglycerides (mg/dL) (p = .0018) and total cholesterol (mg/dL) (p = .0005). Conclusions:The administration of TNF-alpha inhibitors can induce anthropometric changes after 24 weeks, but it does not cause an increase in VAT. The association between low-carbohydrates calorie-restricted diet and anti-TNF-alpha therapy seems to be able to improve the anthropometric profile of psoriasis patients. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results