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2. Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma.

Author

Seyedin, Steven, Gannon, Margaret, Plichta, Kristin, Abushahin, Laith, Berg, Daniel, Arshava, Evgeny, Parekh, Kalpaj, Keech, John, Caster, Joseph, Welsh, James, and Allen, Bryan

Subjects
SBRT, chemoradiation, esophageal cancer, inoperable, recurrence
Abstract

Purpose: This study aimed to investigate the feasibility of stereotactic body radiation therapy (SBRT) as salvage therapy for locally recurrent esophageal cancer. We hypothesized that SBRT would provide durable treated tumor control with minimal associated toxicity in patients with progressive disease after definitive radiation, chemotherapy, and surgical resection. Methods: This single-institution retrospective study assessed outcomes in patients who received SBRT for locoregional failure of esophageal cancer after initial curative-intent treatment. Only patients who had received neoadjuvant chemoradiation (≥41.4 Gy) for esophageal cancer were selected. Subsequent surgical resection was optional but institutional follow-up by an oncologist was required. The primary endpoints of this study were gastrointestinal and constitutional toxicity, scored with the Common Terminology Criteria for Adverse Events v5.0. A secondary outcome, treated-tumor control, was assessed with RECIST v1.1. Results: Nine patients (11 locoregional recurrences) treated with SBRT were reviewed, with a median follow-up time of 10.5 months. Most patients initially presented with T3 (88.9%), N1 (55.6%), moderately differentiated (66.7%) adenocarcinoma (88.9%), and had received a median 50.4 Gy delivered over 28 fractions with concurrent carboplatin/paclitaxel chemotherapy followed by surgical resection. Median time to recurrence was 16.3 months. Median total dose delivered by SBRT was 27.5 Gy (delivered in five fractions). Two patients experienced acute grade 1 fatigue and vomiting. No patient experienced grade 3 or higher toxicity. One patient experienced failure in the SBRT treatment field at 5.8 months after treatment and six patients developed distant failure. The median progression-free survival time for SBRT-treated tumors was 5.0 months, and median overall survival time was 12.9 months. Conclusions: This single-institution study demonstrated the feasibility of SBRT for locoregional recurrence of esophageal cancer with minimal treatment-related toxicity and high rates of treated tumor control. Prospective studies identifying ideal salvage SBRT candidates for locoregional failure as well as validating its safety are needed.

Published
2020

7. Letters

Author

Gannon, Margaret A. and Nichols, Martha

Published
2008

11. Safety and Efficacy of Stereotactic Body Radiation Therapy for Locoregional Recurrences After Prior Chemoradiation for Advanced Esophageal Carcinoma

Author

Seyedin, Steven N., primary, Gannon, Margaret K., additional, Plichta, Kristin A., additional, Abushahin, Laith, additional, Berg, Daniel J., additional, Arshava, Evgeny V., additional, Parekh, Kalpaj R., additional, Keech, John C., additional, Caster, Joseph M., additional, Welsh, James W., additional, and Allen, Bryan G., additional

Published
2020
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17. The invisible mothers

Author

Gannon, Margaret A. and Nichols, Martha

Subjects
Literature/writing, Women's issues/gender studies
Abstract

Dear Editor, Upon reading Martha Nichols' review of two books on transnational and cross racial adoption (September/October 2007), I feel compelled to raise a voice for the birth mothers whom [...]

Published
2008

18. Clochar na Trócaire, Leac an Anfa, Cathair na Mart

Author

Clochar Na Trócaire, Leac An Anfa, Treasa, Fair, Willie, Gannon, Hollie, Mortimer, Loreto, Gannon, Maggie, Gannon, Mollie, Gavin, Tommie, Horan, Mr T., Farrell, Paddy, Malley, Therese O', Lydon, Peggie, Gill, Johnnie, Fair, James, Gill, John, Fair, Tessie, Malley, Julia Agnes O', Gill, Sal, Gannon, Margaret, Donnell, Mick O, Cummins, Jackie, Farrell, Theresa, Farrell, Kathleen, Malley, Margaret Therese O', and Malley, Teresa O'

Subjects
Limekilns, History, Historic sites, Leic Ainimhe, Frost, Saint Brigid's Day, Smithing, Riddles, Cemeteries, Marriage, Potatoes, Folklore, Jokes, Saint Stephen's Day, Commerce, Leprechauns, Saint Patrick's Day, Bread, Supernatural beings, Ash Wednesday, May (Month), Animal culture, Famine, 1845-1852, Textile industry, Prayers, Irish Travellers (Nomadic people), Halloween, Folk poetry, local legends, Pentecost Festival, Toys, Manners and customs, Birds, New Year, Epiphany, Leckanvy, Weather, Treasure troves, Basket making, Drowning, Traditional medicine, Dwellings, Christmas, Roads, Shoes, Easter, Ringforts, Clothing and dress, Food, Good Friday, Butter, Recreation, Ireland, Proverbs, Carnival
Abstract

A collection of folklore and local history stories from Clochar na Trócaire, Leac an Anfa, Cathair na Mart (school) (Leckanvy, Co. Mayo), collected as part of the Schools' Folklore Scheme, 1937-1938 under the supervision of teacher An tSr. Treasa., Hidden Treasure - Story Number 1 / Fair, Willie -- Hidden Treasure - Story Number 2 / Gannon, Hollie -- Hidden Treasure - Story Number 3 / Mortimer, Loreto -- Funny Stories - Number 1 / Gannon, Maggie -- Funny Stories - Story Number 3 / Gannon, Maggie -- Funny Stories - Story Number 4 / Gannon, Mollie -- Collection of Riddles -- Weather-Lore -- Local Heroes -- Local Happenings - The Achill Drowning -- Local Drowning in Clew Bay / Gavin, Tommie -- Without title -- Severe Weather - A Snowstorm / Gannon, Maggie -- Last Severe Storm / Horan, Mr T. -- Old Crafts - How a Cleeve is Made / Farrell, Paddy -- Old Crafts - Basket-Making / Malley, Therese O' -- Old Crafts - Spinning / Malley, Therese O' -- How Lime is Burned / Malley, Therese O' -- Local Marriages Customs -- Local Marriage Customs -- Local Marriage Customs - In the Penal Times -- Local Place Names - Lecanvey -- Local Place Names - Thornhill -- Bird-Lore -- Homemade Toys / Lydon, Peggie -- Homemade Toys - How a Popgun Is Made / Gill, Johnnie -- Homemade Toys - How a Catapult Is Made -- Homemade Toys - Cradle Birds / Fair, James -- Homemade Toys - How to Make a Snare / Fair, Willie -- Lore of Certain Days -- Travelling Folk -- Fairy Forts -- Local Poets -- On the Departure of the Monks for Roscrea -- Famine Times / Gavin, Tommie -- Dice / Fair, James -- Game I Play - The Ghost in the Well / Gill, John -- Game I Play - Skipping / Gavin, Tommie -- Game I Play Indoor / Fair, Tessie -- Game I Play - Four Corners / Malley, Julia Agnes O' -- Game I Play - Blind Man's Buff / Gill, Sal -- Game I Play indoor - Colours / Gannon, Margaret -- Hide and Go Seek / Donnell, Mick O -- Blind Man's Buff / Cummins, Jackie -- Game I Play - Chip Chop Cherry / Farrell, Theresa -- Game I Play - Grandmother Grey / Gannon, Mollie -- Game I Play - Boxes / Gannon, Mollie -- Game I Play - Cat and Rat / Farrell, Kathleen -- Game I Play / Malley, Margaret Therese O' -- Games -- Local Roads -- My Home District - Lecanvey -- My Home District - Thornhill -- My Home District - Gloshpatrick -- My Home District - Carramacloughlin -- Our Holy Wells -- Herbs / Gill, Johnnie -- Potato Crop -- Proverbs -- Festival Customs - St Brigid's Day -- Festival Customs - St Patrick's Day -- Festival Customs - Shrove Tuesday -- Festival Customs - Ash Wednesday -- Festival Customs - Holy Thursday -- Festival Customs - Good Friday -- Festival Customs - Easter Sunday -- Festival Customs - Whit Sunday and Whit Monday -- Festival Customs - May Day -- Festival Customs - Hallow Eve -- Festival Customs - Christmas Feasts -- Festival Customs - St Stephen's Day -- Festival Customs - New Year's Day -- Festival Customs - Feast of Epiphany -- Care of our Farm Animals -- Churning -- Care of the Feet / Mortimer, Loreto -- Local Forge -- Clothes Made Locally -- Local Patron Saint / Gill, Johnnie -- Local Patron Saint -- Local Fairs -- Bread / Gannon, Maggie -- Old Story / Fair, James -- Local Monuments -- Food in Olden Times / Gannon, Maggie -- Buying and Selling / Gill, Johnnie -- Old Houses -- Stories of Giants and Warriors -- Leprechaun or Mermaid -- Local Ruins -- Religious Stories - Bob of the Reek -- Old Graveyards -- Collection of Prayers -- Emblems and Objects of Value / Malley, Teresa O', Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.

Published
1937
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