430 results on '"Gan, Jianhua"'
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2. Structural and functional insights into the helicase protein E5 of Mpox virus
3. Molecular basis and engineering of miniature Cas12f with C-rich PAM specificity
4. Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma
5. Shade-induced RTFL/DVL peptides negatively regulate the shade response by directly interacting with BSKs in Arabidopsis
6. Cofactor binding triggers rapid conformational remodelling of the active site of a methyltransferase ribozyme
7. Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists
8. Structural insights into partner selection for MYB and bHLH transcription factor complexes
9. Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
10. TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization
11. Crystal structures and insights into precursor tRNA 5’-end processing by prokaryotic minimal protein-only RNase P
12. Structural insights of the elongation factor EF-Tu complexes in protein translation of Mycobacterium tuberculosis
13. Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP
14. Structure-guided development of Pb2+-binding DNA aptamers
15. Structural insights into the biosynthetic mechanism of Nα-GlyT and 5-NmdU hypermodifications of DNA.
16. Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein
17. NAP1-Related Protein 1 (NRP1) has multiple interaction modes for chaperoning histones H2A-H2B
18. Structural and biochemical insights into small RNA 3' end trimming by Arabidopsis SDN1.
19. Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action.
20. The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences
21. Histamine activates HinK to promote the virulence of Pseudomonas aeruginosa
22. Crystallization and Structural Determination of 8–17 DNAzyme
23. Citrate serves as a signal molecule to modulate carbon metabolism and iron homeostasis in Staphylococcus aureus.
24. Selective cadmium regulation mediated by a cooperative binding mechanism in CadR
25. Structural analysis of Phytophthora suppressor of RNA silencing 2 (PSR2) reveals a conserved modular fold contributing to virulence
26. Catalytic-state structure and engineering of Streptococcus thermophilus Cas9
27. Structural Insight into Polymerase Mechanism via a Chiral Center Generated with a Single Selenium Atom
28. Structural and functional studies of PCNA from African swine fever virus
29. Structures and implications of the C962R protein of African swine fever virus
30. High-resolution crystal structure of RNA kinase ArK1 from G. acetivorans
31. Purification and enzymatic characterization of the RNA ligase RTCB from Thermus thermophilus
32. OsChz1 acts as a histone chaperone in modulating chromatin organization and genome function in rice
33. Structure insight of GSDMD reveals the basis of GSDMD autoinhibition in cell pyroptosis
34. Structure-guided protein engineering increases enzymatic activities of the SGNH family esterases
35. A unique DNA-binding mode of African swine fever virus AP endonuclease
36. Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues
37. Crystal structures and identification of novel Cd2+-specific DNA aptamer
38. The transcription factor OsSUF4 interacts with SDG725 in promoting H3K36me3 establishment
39. Structure-based insights into mechanism of endoperoxidase FtmOx1 catalyzed reactions
40. Identification and Characterization of a Novel Prokaryotic Peptide: N-GLYCOSIDASE FROM ELIZABETHKINGIA MENINGOSEPTICA
41. PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa
42. Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1
43. Structural insights into the effects of 2′-5′ linkages on the RNA duplex
44. Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties.
45. Acetylation of lysine 182 inhibits the ability of Mycobacterium tuberculosis DosR to bind DNA and regulate gene expression during hypoxia
46. Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target
47. Structure–Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors
48. Fluorescent Aptaswitch for Detection of Lead Ions
49. Xenogeneic nucleoid-associated EnrR thwarts H-NS silencing of bacterial virulence with unique DNA binding
50. Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella
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