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This article highlights the main landmarks in the history of the Clinic of ENT diseases at I.M. Sechenov First Moscow State Medical University, from the days of its foundation up to the present time. The main scientific and clinical aspects of it activities in different periods under the guidance of the outstanding Russian otorhynolaryngologists are described.

The experiments were made to study CO2-laser ability to promote spontaneous formation of nasal septum cartilage. Laser-induced changes in physical and histological characteristics of the cartilage tissue were followed up. Optimal regimens of radiation were selected which allowed to modify cartilage shape without impairment of its morphological and histological structure. In vivo tests were performed on rabbit auricular floor cartilage. The present shape of the cartilage remained stable. It is inferred that laser energy may be a promising tool in plastic ENT surgery.

Investigations of structural and mechanical properties of cartilage tissue exposed to laser radiation have shown the effect of laser relaxation of the tension existing in the cartilage and changes in the latter form to be due to phasic transition of water from bound into free state. Laser radiation does not induce macroscopic transformations of the matrix structure. New form of the cartilage proved stable this offering new prospects for wide application of this technique in otorhinolaryngology and plastic surgery.