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1,216 results on '"Gambacorta, Maria"'

4. Imaging in pelvic exenteration—a multidisciplinary practice guide from the ESGAR-SAR-ESUR-PelvEx collaborative group

Author

Nougaret, Stephanie, Lambregts, Doenja M. J., Beets, Geerard L., Beets-Tan, Regina G. H., Blomqvist, Lennart, Burling, David, Denost, Quentin, Gambacorta, Maria A., Gui, Benedetta, Klopp, Ann, Lakhman, Yulia, Maturen, Kate E., Manfredi, Riccardo, Petkovska, Iva, Russo, Luca, Shinagare, Atul B., Stephenson, James A., Tolan, Damian, Venkatesan, Aradhana M., Quyn, Aaron J., and Forstner, Rosemarie

Published
2024
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5. Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis

Author

Azimi, Amirali, Tabatabaei, Fatemeh Sadat, Kolahdouzan, Kasra, Rashidian, Hamideh, Nourbakhsh, Forouzan, Parizi, Maryam Abedini, Darzikolaee, Nima Mousavi, Bayani, Reyhaneh, Salarvand, Samaneh, Sharifian, Azadeh, Bagheri, Farzaneh, Rezaei, Saeed, Nabian, Naeim, Nazari, Reza, Mohammadi, Negin, Babaei, Mohammad, Lashkari, Marzieh, Farhan, Farshid, Aghili, Mahdi, Couñago, Felipe, Gambacorta, Maria Antonietta, and Ghalehtaki, Reza

Published
2024
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10. Radiomics-enhanced early regression index for predicting treatment response in rectal cancer: a multi-institutional 0.35 T MRI-guided radiotherapy study

Author

Boldrini, Luca, Chiloiro, Giuditta, Cusumano, Davide, Yadav, Poonam, Yu, Gao, Romano, Angela, Piras, Antonio, Votta, Claudio, Placidi, Lorenzo, Broggi, Sara, Catucci, Francesco, Lenkowicz, Jacopo, Indovina, Luca, Bassetti, Michael F., Yang, Yingli, Fiorino, Claudio, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2024
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11. Error-Correcting Methodology for Evaluating Compliance to Clinical Guidelines: A Case Study on Rectal Cancer

Author

Savino, Mariachiara, Fernandez-Llatas, Carlos, Gatta, Roberto, Chiloiro, Giuditta, Di Franco, Silvia, Ibanez-Sanchez, Gema, Valero-Ramon, Zoe, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Damiani, Andrea, van der Aalst, Wil, Series Editor, Ram, Sudha, Series Editor, Rosemann, Michael, Series Editor, Szyperski, Clemens, Series Editor, Guizzardi, Giancarlo, Series Editor, De Smedt, Johannes, editor, and Soffer, Pnina, editor

Published
2024
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12. Definitive chemoradiation in vulvar squamous cell carcinoma: outcome and toxicity from an observational multicenter Italian study on vulvar cancer (OLDLADY 1.1)

Author

Macchia, Gabriella, Lancellotta, Valentina, Ferioli, Martina, Casà, Calogero, Pezzulla, Donato, Pappalardi, Brigida, Laliscia, Concetta, Ippolito, Edy, Di Muzio, Jacopo, Huscher, Alessandra, Tortoreto, Francesca, Boccardi, Mariangela, Lazzari, Roberta, Perrone, Anna Myriam, Raspagliesi, Francesco, Gadducci, Angiolo, Garganese, Giorgia, Fragomeni, Simona Maria, Ferrandina, Gabriella, Morganti, Alessio Giuseppe, Gambacorta, Maria Antonietta, and Tagliaferri, Luca

Published
2024
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16. REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer

Author

Boggi, Ugo, Kauffmann, Emanuele, Napoli, Niccolò, Barreto, S. George, Besselink, Marc G., Fusai, Giuseppe K., Hackert, Thilo, Abu Hilal, Mohammad, Marchegiani, Giovanni, Salvia, Roberto, Shrikhande, Shailesh V., Truty, Mark, Werner, Jens, Wolfgang, Christopher L., Bannone, Elisa, Capretti, Giovanni, Cattelani, Alice, Coppola, Alessandro, Cucchetti, Alessandro, De Sio, Davide, Di Dato, Armando, Di Meo, Giovanna, Fiorillo, Claudio, Gianfaldoni, Cesare, Ginesini, Michael, Hidalgo Salinas, Camila, Lai, Quirino, Miccoli, Mario, Montorsi, Roberto, Pagnanelli, Michele, Poli, Andrea, Ricci, Claudio, Sucameli, Francesco, Tamburrino, Domenico, Viti, Virginia, Addeo, Pietro F., Alfieri, Sergio, Bachellier, Philippe, Baiocchi, Gian Luca, Balzano, Gianpaolo, Barbarello, Linda, Brolese, Alberto, Busquets, Juli, Butturini, Giovanni, Caniglia, Fabio, Caputo, Damiano, Casadei, Riccardo, Chunhua, Xi, Colangelo, Ettore, Coratti, Andrea, Costa, Francesca, Crafa, Francesco, Dalla Valle, Raffaele, De Carlis, Luciano, de Wilde, Roeland F., Del Chiaro, Marco, Di Benedetto, Fabrizio, Di Sebastiano, Pierluigi, Dokmak, Safi, Hogg, Melissa, Egorov, Vyacheslav I., Ercolani, Giorgio, Ettorre, Giuseppe Maria, Falconi, Massimo, Ferrari, Giovanni, Ferrero, Alessandro, Filauro, Marco, Giardino, Alessandro, Grazi, Gian Luca, Gruttadauria, Salvatore, Izbicki, Jakob R, Jovine, Elio, Katz, Matthew, Keck, Tobias, Khatkov, Igor, Kiguchi, Gozo, Kooby, David, Lang, Hauke, Lombardo, Carlo, Malleo, Giuseppe, Massani, Marco, Mazzaferro, Vincenzo, Memeo, Riccardo, Miao, Yi, Mishima, Kohei, Molino, Carlo, Nagakawa, Yuichi, Nakamura, Masafumi, Nardo, Bruno, Panaro, Fabrizio, Pasquali, Claudio, Perrone, Vittorio, Rangelova, Elena, Liu, Rong, Romagnoli, Renato, Romito, Raffaele, Rosso, Edoardo, Schulick, Richard, Siriwardena, Ajith, Spampinato, Marcello Giuseppe, Strobel, Oliver, Testini, Mario, Troisi, Roberto Ivan, Uzunoglo, Faik G., Valente, Roberto, Veneroni, Luigi, Zerbi, Alessandro, Vicente, Emilio, Vistoli, Fabio, Vivarelli, Marco, Wakabayashi, Go, Zanus, Giacomo, Zureikat, Amer, Zyromski, Nicholas J., Coppola, Roberto, D’Andrea, Vito, Davide, José, Dervenis, Christos, Frigerio, Isabella, Konlon, Kevin C., Michelassi, Fabrizio, Montorsi, Marco, Nealon, William, Portolani, Nazario, Sousa Silva, Donzília, Bozzi, Giuseppe, Ferrari, Viviana, Trivella, Maria G., Cameron, John, Clavien, Pierre-Alain, Asbun, Horacio J., Boraschi, Piero, Campani, Daniela, Cappelli, Carla, Cioni, Roberto, Dominici, Massimo, Esposito, Irene, Gambacorta, Maria A, Marciano, Emanuele, Masi, Gianluca, Morganti, Alessio, Mutignani, Massimiliano, Neri, Emanuele, Paiar, Fabiola, Reni, Michele, Rotondo, Maria Isabella, Silvestris, Nicola, Tortora, Giampaolo, Vasile, Enrico, and Volterrani, Duccio

Published
2024
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18. Impact of body composition parameters on radiation therapy compliance in locally advanced rectal cancer: A retrospective observational analysis

Author

Chiloiro, Giuditta, Cintoni, Marco, Palombaro, Marta, Romano, Angela, Reina, Sara, Pulcini, Gabriele, Corvari, Barbara, Di Franco, Silvia, Meldolesi, Elisa, Egidi, Gabriele, Grassi, Futura, Raoul, Pauline, Rinninella, Emanuele, Gasbarrini, Antonio, Mele, Maria Cristina, and Gambacorta, Maria Antonietta

Published
2024
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20. Pattern of care for re-irradiation in locally recurrent rectal cancer: a national survey on behalf of the AIRO gastrointestinal tumors study group

Author

Mantello, Giovanna, Galofaro, Elena, Caravatta, Luciana, Di Carlo, Clelia, Montrone, Sabrina, Arpa, Donatella, Chiloiro, Giuditta, De Paoli, Antonino, Donato, Vittorio, Gambacorta, Maria Antonietta, Genovesi, Domenico, Lupattelli, Marco, Macchia, Gabriella, Montesi, Giampaolo, Niespolo, Rita Marina, Palazzari, Elisa, Pontoriero, Antonio, Scricciolo, Melissa, Valvo, Francesca, and Franco, Pierfrancesco

Published
2023
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21. Efficacy of stereotactic body radiotherapy and response prediction using artificial intelligence in oligometastatic gynaecologic cancer

Author

Macchia, Gabriella, Cilla, Savino, Pezzulla, Donato, Campitelli, Maura, Laliscia, Concetta, Lazzari, Roberta, Draghini, Lorena, Fodor, Andrei, D'Agostino, Giuseppe R., Russo, Donatella, Balcet, Vittoria, Ferioli, Martina, Vicenzi, Lisa, Raguso, Arcangela, Di Cataldo, Vanessa, Perrucci, Elisabetta, Borghesi, Simona, Ippolito, Edy, Gentile, Piercarlo, De Sanctis, Vitaliana, Titone, Francesca, Delle Curti, Clelia Teresa, Huscher, Alessandra, Gambacorta, Maria Antonietta, Ferrandina, Gabriella, Morganti, Alessio G., and Deodato, Francesco

Published
2024
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23. Rectal Cancer

Author

Fokas, Emmanouil, Gani, Cihan, Valentini, Vincenzo, Rödel, Claus, Gambacorta, Maria Antonietta, Grosu, Anca-Ligia, editor, Nieder, Carsten, editor, and Nicolay, Nils Henrik, editor

Published
2023
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26. Machine-learning prediction of treatment response to stereotactic body radiation therapy in oligometastatic gynecological cancer: A multi-institutional study

Author

Cilla, Savino, Campitelli, Maura, Antonietta Gambacorta, Maria, Michela Rinaldi, Raffaella, Deodato, Francesco, Pezzulla, Donato, Romano, Carmela, Fodor, Andrei, Laliscia, Concetta, Trippa, Fabio, De Sanctis, Vitaliana, Ippolito, Edy, Ferioli, Martina, Titone, Francesca, Russo, Donatella, Balcet, Vittoria, Vicenzi, Lisa, Di Cataldo, Vanessa, Raguso, Arcangela, Giuseppe Morganti, Alessio, Ferrandina, Gabriella, and Macchia, Gabriella

Published
2024
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29. May we routinely spare hippocampal region in primary central nervous system lymphoma during whole brain radiotherapy?

Author

Mazzarella, Ciro, Chiesa, Silvia, Toppi, Lucrezia, Hohaus, Stefan, Gaudino, Simona, D’Alo, Francesco, Dinapoli, Nicola, Davide, Resta, Zinicola, Tiziano, Bracci, Serena, Martino, Antonella, Beghella Bartoli, Francesco, Lepre, Elisabetta, Bertolini, Roberta, Mariani, Silvia, Colosimo, Cesare, Frascino, Vincenzo, Mattiucci, Gian Carlo, Gambacorta, Maria Antonietta, Valentini, Vincenzo, and Balducci, Mario

Published
2023
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30. The Italian version of the Pediatric Quality of Life Inventory™ (PEDSQL™) 3.0 healthcare satisfaction hematology/oncology module: reliability and validity in radiation oncology

Author

Marconi, Elisa, Beghella Bartoli, Francesco, Meldolesi, Elisa, Mariani, Silvia, Panza, Giulia, Nardangeli, Alessia, Dinapoli, Loredana, Lees, Teresa Carmen, Guido, Antonella, Mastronuzzi, Angela, Ruggiero, Antonio, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Balducci, Mario, Chieffo, Daniela Pia Rosaria, and Chiesa, Silvia

Published
2023
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32. Magnetic resonance guided SBRT reirradiation in locally recurrent prostate cancer: a multicentric retrospective analysis

Author

Boldrini, Luca, Romano, Angela, Chiloiro, Giuditta, Corradini, Stefanie, De Luca, Viola, Verusio, Valeria, D’Aviero, Andrea, Castelluccia, Alessandra, Alitto, Anna Rita, Catucci, Francesco, Grimaldi, Gianmarco, Trapp, Christian, Hörner-Rieber, Juliane, Marchesano, Domenico, Frascino, Vincenzo, Mattiucci, Gian Carlo, Valentini, Vincenzo, Gentile, Piercarlo, and Gambacorta, Maria Antonietta

Published
2023
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34. Psychological Experiences of Parents of Pediatric Cancer Patients during and after COVID-19 Pandemic

Author

Guido, Antonella, Marconi, Elisa, Peruzzi, Laura, Dinapoli, Nicola, Tamburrini, Gianpiero, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Chiesa, Silvia, Gambacorta, Maria Antonietta, Ruggiero, Antonio, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Maurizi, Palma (ORCID:0000-0002-5930-0193), Mastrangelo, Stefano (ORCID:0000-0002-3305-6014), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Ruggiero, Antonio (ORCID:0000-0002-6052-3511), Guido, Antonella, Marconi, Elisa, Peruzzi, Laura, Dinapoli, Nicola, Tamburrini, Gianpiero, Attinà, Giorgio, Romano, Alberto, Maurizi, Palma, Mastrangelo, Stefano, Chiesa, Silvia, Gambacorta, Maria Antonietta, Ruggiero, Antonio, Chieffo, Daniela Pia Rosaria, Marconi, Elisa (ORCID:0000-0001-6722-8390), Tamburrini, Gianpiero (ORCID:0000-0002-7139-5711), Maurizi, Palma (ORCID:0000-0002-5930-0193), Mastrangelo, Stefano (ORCID:0000-0002-3305-6014), Chiesa, Silvia (ORCID:0000-0003-0168-3459), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), and Ruggiero, Antonio (ORCID:0000-0002-6052-3511)

Abstract

This study aimed to evaluate how the COVID-19 pandemic affected the psychological well-being of parents of pediatric oncology patients two years after the pandemic started. The authors' objective was to make a detailed comparison between the data collected in the current study and the data gathered in the previous research with the aim of observing any changes, whether for better or worse, at the psychological level in the caregivers of the patients in question. This research could be of great use for monitoring the psychological health of the sample and for being able to intervene promptly in the event of the worsening of the reported symptoms. Background: Family members dealing with the devastating impact of a cancer diagnosis are now facing even greater vulnerability due to the COVID-19 pandemic. Alongside the already overwhelming trauma, they must also bear the distressing burden of the infection risks. The purpose of this study was to examine and explore the effects in parents of pediatric cancer patients two years after the start of the COVID-19 pandemic to compare these data with the previous data. Methods: We conducted a single-center prospective observational study, enrolling 75 parents of 42 pediatric oncology patients. Four questionnaires (IES-R; PSS; STAI-Y and PedsQL) were given to the parents 2 years after the first evaluation. Results: The bivariate matrix of correlation found a strong significant positive correlation between IES-R and PSS scores (r = 0.526, p < 0.001) as in T1. Stress symptoms (t = 0.00, p < 0.001) and levels of anxiety (trait) (t = 0.32, p < 0.001) remained unchanged; anxiety state levels appeared to have increased (t = 0.425, p < 0.001); there was a significant decrease in the PedsQL tot (t = 5.25, p < 0.001). Conclusions: The COVID-19 pandemic has influenced the levels of stress and anxiety of parents and the quality of life of patients, also correlating with the traumatic impact of the diagnosis.

Published
2024

35. Is PET Radiomics Useful to Predict Pathologic Tumor Response and Prognosis in Locally Advanced Cervical Cancer?

Author

Collarino, Angela, Feudo, Vanessa, Pasciuto, Tina, Florit, Anita, Pfaehler, Elisabeth, de Summa, Marco, Bizzarri, Nicolò, Annunziata, Salvatore, Zannoni, Gian Franco, de Geus-Oei, Lioe-Fee, Ferrandina, Maria Gabriella, Gambacorta, Maria Antonietta, Scambia, Giovanni, Boellaard, Ronald, Sala, Evi, Rufini, Vittoria, van Velden, Floris HP, Pasciuto, Tina (ORCID:0000-0003-2959-8571), Annunziata, Salvatore (ORCID:0000-0003-3241-1501), Zannoni, Gian Franco (ORCID:0000-0003-1809-129X), Ferrandina, Gabriella (ORCID:0000-0003-4672-4197), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Scambia, Giovanni (ORCID:0000-0003-2758-1063), Sala, Evis, Rufini, Vittoria (ORCID:0000-0002-2052-8078), Collarino, Angela, Feudo, Vanessa, Pasciuto, Tina, Florit, Anita, Pfaehler, Elisabeth, de Summa, Marco, Bizzarri, Nicolò, Annunziata, Salvatore, Zannoni, Gian Franco, de Geus-Oei, Lioe-Fee, Ferrandina, Maria Gabriella, Gambacorta, Maria Antonietta, Scambia, Giovanni, Boellaard, Ronald, Sala, Evi, Rufini, Vittoria, van Velden, Floris HP, Pasciuto, Tina (ORCID:0000-0003-2959-8571), Annunziata, Salvatore (ORCID:0000-0003-3241-1501), Zannoni, Gian Franco (ORCID:0000-0003-1809-129X), Ferrandina, Gabriella (ORCID:0000-0003-4672-4197), Gambacorta, Maria Antonietta (ORCID:0000-0001-5455-8737), Scambia, Giovanni (ORCID:0000-0003-2758-1063), Sala, Evis, and Rufini, Vittoria (ORCID:0000-0002-2052-8078)

Abstract

This study investigated whether radiomic features extracted from pretreatment [18F]FDG PET could improve the prediction of both histopathologic tumor response and survival in patients with locally advanced cervical cancer (LACC) treated with neoadjuvant chemoradiotherapy followed by surgery compared with conventional PET parameters and histopathologic features. Methods: The medical records of all consecutive patients with LACC referred between July 2010 and July 2016 were reviewed. [18F]FDG PET/CT was performed before neoadjuvant chemoradiotherapy. Radiomic features were extracted from the primary tumor volumes delineated semiautomatically on the PET images and reduced by factor analysis. A receiver-operating-characteristic analysis was performed, and conventional and radiomic features were dichotomized with Liu's method according to pathologic response (pR) and cancer-specific death. According to the study protocol, only areas under the curve of more than 0.70 were selected for further analysis, including logistic regression analysis for response prediction and Cox regression analysis for survival prediction. Results: A total of 195 patients fulfilled the inclusion criteria. At pathologic evaluation after surgery, 131 patients (67.2%) had no or microscopic (≤3 mm) residual tumor (pR0 or pR1, respectively); 64 patients (32.8%) had macroscopic residual tumor (>3 mm, pR2). With a median follow-up of 76.0 mo (95% CI, 70.7-78.7 mo), 31.3% of patients had recurrence or progression and 20.0% died of the disease. Among conventional PET parameters, SUVmean significantly differed between pathologic responders and nonresponders. Among radiomic features, 1 shape and 3 textural features significantly differed between pathologic responders and nonresponders. Three radiomic features significantly differed between presence and absence of recurrence or progression and between presence and absence of cancer-specific death. Areas under the curve were less than 0.70 for all param

Published
2024

36. Prognostic Score in Radiotherapy Practice for Palliative Treatments (PROPHET) Study for Bone Metastases: An Investigation Into the Clinical Effect on Treatment Prescription

Author

Cellini, Francesco, Di Rito, Alessia, Siepe, Giambattista, Pastore, Francesco, Lattanzi, Elisabetta, Meaglia, Ilaria, Tozzi, Angelo, Manfrida, Stefania, Longo, Silvia, Saldi, Simonetta, Cassese, Raffaele, Arcidiacono, Fabio, Fiore, Michele, Masiello, Valeria, Mazzarella, Ciro, Diroma, Antonio, Miccichè, Francesco, Maurizi, Francesca, Dominici, Luca, Scorsetti, Marta, Santarelli, Mario, Fusco, Vincenzo, Aristei, Cynthia, Deodato, Francesco, Gambacorta, Maria A., Maranzano, Ernesto, Muto, Paolo, Valentini, Vincenzo, Morganti, Alessio G., Marino, Lorenza, Donati, Costanza M., and Di Franco, Rossella

Published
2023
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37. Predictive and prognostic value of inflammatory markers in locally advanced rectal cancer (PILLAR) – A multicentric analysis by the Italian Association of Radiotherapy and Clinical Oncology (AIRO) Gastrointestinal Study Group

Author

Chiloiro, Giuditta, Romano, Angela, Mariani, Silvia, Macchia, Gabriella, Giannarelli, Diana, Caravatta, Luciana, Franco, Pierfrancesco, Boldrini, Luca, Arcelli, Alessandra, Bacigalupo, Almalina, Belgioia, Liliana, Fontana, Antonella, Meldolesi, Elisa, Montesi, Giampaolo, Niespolo, Rita Marina, Palazzari, Elisa, Piva, Cristina, Valentini, Vincenzo, and Gambacorta, Maria Antonietta

Published
2023
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38. A predictive model of polymetastatic disease from a multicenter large retrospectIve database on colorectal lung metastases treated with stereotactic ablative radiotherapy: The RED LaIT-SABR study

Author

Nicosia, Luca, Franceschini, Davide, Perrone-Congedi, Francesca, Molinari, Alessandro, Gerardi, Marianna Alessandra, Rigo, Michele, Mazzola, Rosario, Perna, Marco, Scotti, Vieri, Fodor, Andrei, Iurato, Aurelia, Pasqualetti, Francesco, Gadducci, Giovanni, Chiesa, Silvia, Niespolo, Rita Marina, Bruni, Alessio, Cappelli, Anna, D'Angelo, Elisa, Borghetti, Paolo, Di Marzo, Alessandro, Ravasio, Andrea, De Bari, Berardino, Sepulcri, Matteo, Aiello, Dario, Mortellaro, Gianluca, Sangalli, Claudia, Franceschini, Marzia, Montesi, Giampaolo, Aquilanti, Francesco Maria, Lunardi, Gianluigi, Valdagni, Riccardo, Fazio, Ivan, Scarzello, Giovanni, Vavassori, Vittorio, Maranzano, Ernesto, Maria Magrini, Stefano, Arcangeli, Stefano, Gambacorta, Maria Antonietta, Valentini, Vincenzo, Paiar, Fabiola, Ramella, Sara, Di Muzio, Nadia Gisella, Loi, Mauro, Jereczek-Fossa, Barbara Alicja, Casamassima, Franco, Osti, Mattia Falchetto, Scorsetti, Marta, and Alongi, Filippo

Published
2023
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39. External validation of a composite bio-humoral index in anal cancer patients undergoing concurrent chemoradiation

Author

Franco, Pierfrancesco, Porreca, Annamaria, Mantello, Giovanna, Valvo, Francesca, Gasparini, Lucrezia, Slim, Najla, Manfrida, Stefania, De Felice, Francesca, Gerardi, Marianna A., Vagge, Stefano, Krengli, Marco, Palazzari, Elisa, Osti, Mattia Falchetto, Gonnelli, Alessandra, Catalano, Gianpiero, Pittoni, Patrizia, Ivaldi, Giovani B., Lupattelli, Marco, Rosetto, Maria Elena, Niespolo, Rita Marina, Guido, Alessandra, Durante, Oreste, Macchia, Gabriella, Munoz, Fernando, El Khouzai, Badr, Lucido, Maria Rosaria, Arcadipane, Francesca, Casadei Gardini, Andrea, Maria D'Angelillo, Rolando, Gambacorta, Maria Antonietta, Genovesi, Domenico, Di Nicola, Marta, and Caravatta, Luciana

Published
2022
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41. Evaluation of early regression index as response predictor in cervical cancer: A retrospective study on T2 and DWI MR images

Author

Cusumano, Davide, Russo, Luca, Gui, Benedetta, Autorino, Rosa, Boldrini, Luca, D'Erme, Luca, Persiani, Salvatore, Catucci, Francesco, Broggi, Sara, Panza, Giulia, Nardangeli, Alessia, Campitelli, Maura, Ferrandina, Gabriella, Macchia, Gabriella, Fiorino, Claudio, Valentini, Vincenzo, Scambia, Giovanni, Manfredi, Riccardo, and Gambacorta, Maria Antonietta

Published
2022
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44. BRIDGE −1 TRIAL: BReak Interval Delayed surgery for Gastrointestinal Extraperitoneal rectal cancer, a multicentric phase III randomized trial

Author

Chiloiro, Giuditta, Meldolesi, Elisa, Corvari, Barbara, Romano, Angela, Barbaro, Brunella, Coco, Claudio, Crucitti, Antonio, Genovesi, Domenico, Lupattelli, Marco, Mantello, Giovanna, Menghi, Roberta, Falchetto Osti, Mattia, Persiani, Roberto, Petruzziello, Lucio, Ricci, Riccardo, Sofo, Luigi, Valentini, Chiara, De Paoli, Antonino, Valentini, Vincenzo, and Antonietta Gambacorta, Maria

Published
2022
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45. Retrospective Dosimetric Comparison of HDR Interventional Radiotherapy (Brachytherapy) Versus Planning with VMAT and Electron Beam Therapy for Non-Melanoma Skin Cancer Treatment.

Author

Placidi, Elisa, Fionda, Bruno, Rosa, Enrico, Lancellotta, Valentina, Napolitano, Antonio, De Angeli, Martina, Ciasca, Gabriele, Pastore, Francesco, Gambacorta, Maria Antonietta, Tagliaferri, Luca, and De Spirito, Marco

Subjects
VOLUMETRIC-modulated arc therapy, MEDICAL dosimetry, RADIOISOTOPE brachytherapy, CANCER treatment, SKIN cancer
Abstract

This study compares dosimetric outcomes of high-dose-rate (HDR) interventional radiotherapy (IRT) using Iridium-192, Volumetric Modulated Arc Therapy (VMAT), and electron beam therapy for non-melanoma skin cancer (NMSC). A retrospective analysis of 25 patients showed that IRT provided a significantly higher mean dose to the clinical target volume (CTV) compared to VMAT and electron beam therapy. IRT and VMAT had comparable V95%CTV coverage, whilst electron therapy was less feasible for large CTVs. IRT delivered higher surface doses while minimizing deep tissue exposure compared to partial arc VMAT. Our findings support IRT for personalized and effective NMSC treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Optimal Sequence for Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer: An Evidence‐Based Review.

Author

Ghalehtaki, Reza, Nourbakhsh, Forouzan, Abyaneh, Romina, Sharifian, Azadeh, Pashapour‐Khoyi, Sheyda, Aghili, Mahdi, Gambacorta, Maria Antonietta, and Couñago, Felipe

Subjects
TUMOR classification, CONSOLIDATION chemotherapy, INDUCTION chemotherapy, ADJUVANT chemotherapy, NEOADJUVANT chemotherapy, RECTAL cancer
Abstract

Introduction: Historically, multimodal therapeutic strategies involving preoperative chemoradiotherapy (CRT), surgery, and adjuvant chemotherapy (CT) have been employed to treat locally advanced rectal cancer (LARC). Total Neoadjuvant Therapy (TNT) is showing promise in improving outcomes. Despite its benefits, the optimal sequencing within TNT—whether induction chemotherapy should precede or follow chemoradiotherapy—remains a critical question. This study endeavors to explore the effects of different TNT sequencing strategies on patient outcomes, including tumor downstaging, pathological response, organ preservation, and the balance between efficacy and tolerability. Methods: Our methodology entailed a comprehensive literature review conducted on Medline, focusing on recent research, including retrospective studies, systematic reviews, and clinical trials. The review emphasized the comparison of induction chemotherapy versus consolidation chemotherapy within TNT regimens, assessing outcomes such as pathological response, organ preservation rates, and adverse effects. To ensure the selection of appropriate and high‐quality studies, specific inclusion and exclusion criteria were applied. Results: The analysis revealed that induction chemotherapy might lead to decreased adherence to subsequent chemoradiotherapy while offering an early intervention against micrometastasis and potentially improving overall chemotherapy compliance. Conversely, consolidation chemotherapy has been associated with higher pathological complete response (pCR) rates and improved tolerability, indicating its potential for patients requiring local symptom relief or those eligible for a nonoperative management approach. Comparative studies like CAO/ARO/AIO‐12 and the OPRA trials have significantly contributed to our understanding, suggesting that while both strategies have distinct advantages, the choice between induction and consolidation chemotherapy should be tailored based on individual patient profiles and tumor characteristics. Conclusion: This narrative review underscores the importance of a nuanced approach to TNT sequencing in locally advanced rectal cancer, highlighting the need for further research to refine treatment strategies. [ABSTRACT FROM AUTHOR]

Published
2024
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48. A multicenter LArge retrospectIve daTabase on the personalization of stereotactic ABlative radiotherapy use in lung metastases from colon-rectal cancer: The LaIT-SABR study

Author

Nicosia, L., Franceschini, D., Perrone-Congedi, F., Casamassima, F., Gerardi, M.A., Rigo, M., Mazzola, R., Perna, M., Scotti, V., Fodor, A., Iurato, A., Pasqualetti, F., Gadducci, G., Chiesa, S., Niespolo, R.M., Bruni, A., Alicino, G., Frassinelli, L., Borghetti, P., Di Marzo, A., Ravasio, A., De Bari, B., Sepulcri, M., Aiello, D., Mortellaro, G., Sangalli, C., Franceschini, M., Montesi, G., Aquilanti, F.M., Lunardi, G., Valdagni, R., Fazio, I., Scarzello, Giovanni, Corti, L., Vavassori, V., Maranzano, E., Magrini, S.M., Arcangeli, S., Gambacorta, Maria Antonietta, Valentini, V., Paiar, F., Ramella, S., Di Muzio, N.G., Livi, L., Jereczek-Fossa, B.A., Osti, M.F., Scorsetti, M., and Alongi, F.

Published
2022
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49. EROS 2.0 study: evaluation of two interventional radiotherapy (brachytherapy) schedules for endometrial cancer: a comparison of late vaginal toxicity rates

Author

Lancellotta, Valentina, Macchia, Gabriella, Dinapoli, Nicola, Autorino, Rosa, Campitelli, Maura, Nardangeli, Alessia, Salvati, Alessandra, Fionda, Bruno, Casà, Calogero, Cornacchione, Patrizia, Rovirosa, Angeles, Kovács, György, Morganti, Alessio Giuseppe, Ferrandina, Maria Gabriella, Gambacorta, Maria Antonietta, and Tagliaferri, Luca

Published
2022
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50. Rectal Sparing Approach After Neoadjuvant Therapy in Patients with Rectal Cancer: The Preliminary Results of the ReSARCh Trial

Author

Marchegiani, Francesco, Palatucci, Valeria, Capelli, Giulia, Guerrieri, Mario, Belluco, Claudio, Rega, Daniela, Morpurgo, Emilio, Coco, Claudio, Restivo, Angelo, De Franciscis, Silvia, Aschele, Carlo, Perin, Alessandro, Bonomo, Michele, Muratore, Andrea, Spinelli, Antonino, Ramuscello, Salvatore, Bergamo, Francesca, Montesi, Giampaolo, Spolverato, Gaya, Del Bianco, Paola, Gambacorta, Maria Antonietta, Delrio, Paolo, and Pucciarelli, Salvatore

Published
2022
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