289 results on '"Gamba C"'
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2. Utilización de sutura barbada en prótesis total de cadera. Estudio prospectivo aleatorizado
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Serrano Chinchilla, P., Gamba, C., León García, A., Tey Pons, M., and Marqués López, F.
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- 2021
- Full Text
- View/download PDF
3. Commento art. 3 d.lgs. n. 28/2010 - Disciplina applicabile e forma degli atti
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
4. Commento art. 5 quinquies d.lgs. n. 28/2010 - Formazione del magistrato, valutazione del contenzioso definito con mediazione demandata e collaborazione
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
5. Commento art. 7 d.lgs. n. 28/2010 - Effetti sulla ragionevole durata del processo.
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
6. Commento art. 8 l. n. 24/2017 - Tentativo obbligatorio di conciliazione
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
7. Commento art. 5 bis d.lgs. n. 28/2010 - Procedimento di opposizione a decreto ingiuntivo
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
8. Commento art. 6 d.lgs. n. 28/2010 - Durata
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
9. Commento art. 1 d.lgs. n. 28/2010 - Definizioni
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
10. Commento art. 5 sexies d.lgs. n. 28/2010 - Mediazione su clausola contrattuale o statutaria
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
11. Commento art. 5 quater d.lgs. n. 28/2010 - Mediazione demandata dal giudice
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
12. Commento art. 5 d.lgs. n. 28/2010 - Condizione di procedibilità e rapporti con il processo
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
13. Commento art. 2 d.lgs. n. 28/2010 - Controversie oggetto di mediazione
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
14. Commento art. 5 ter d.lgs. n. 28/2010 - Legittimazione in mediazione dell'amministratore di condominio
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
15. Commento art. 8 d.lgs. n. 28/2010 - Procedimento
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
16. Commento art. 8 bis d.lgs. n. 28/2010 - Mediazione in modalità telematica
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
17. Commento art. 4 d.lgs. n. 28/2010 - Accesso alla mediazione
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
18. Commento art. 15 l. n. 24/2017 - Nomina dei consulenti tecnici d'ufficio e dei periti nei giudizi di responsabilità sanitaria
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Carpi, F, Taruffo, M, Gamba, C, Ferraris, F, Carpi, F, Taruffo, M, Gamba, C, and Ferraris, F
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- 2023
19. Tibiotalocalcaneal arthrodesis using a humeral locking plate
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Cabrera Méndez, M.P., Gamba, C., Hernández, E., Molano, J., and Andrade, J.C.
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- 2016
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20. Artrodesis tibiotalocalcánea con placa humeral bloqueada
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Cabrera Méndez, M.P., Gamba, C., Hernández, E., Molano, J., and Andrade, J.C.
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- 2016
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21. Body composition analysis by dual-energy X-ray absorptiometry in young preschool children
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Lifshitz, F, Hecht, J P, Bermúdez, E F, Gamba, C A, Reinoso, J M, Casavalle, P L, Friedman, S M, and Rodriguez, P N
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- 2016
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22. Mesolimbic dopaminergic dysfunction in Parkinson’s disease depression: evidence from a 123I-FP-CIT SPECT investigation
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Frosini, D., Unti, E., Guidoccio, F., Del Gamba, C., Puccini, G., Volterrani, D., Bonuccelli, U., and Ceravolo, R.
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- 2015
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23. Circulating Very-Low-Density Lipoprotein Characteristics Resulting from Fatty Liver in an Insulin Resistance Rat Model
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Zago, V., Lucero, D., Macri, E. V., Cacciagiú, L., Gamba, C. A., Miksztowicz, V., Berg, G., Wikinski, R., Friedman, S., and Schreier, L.
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- 2010
24. Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge
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Vershinina, A. O., Heintzman, P. D., Froese, D. G., Zazula, G., Cassatt-Johnstone, M., Dalén, L., Der Sarkissian, C., Dunn, S. G., Ermini, L., Gamba, C., Groves, P., Kapp, J. D., Mann, D. H., Seguin-Orlando, A., Southon, J., Stiller, M., Wooller, M. J., Baryshnikov, G., Gimranov, D., Scott, E., Hall, E., Hewitson, S., Kirillova, I., Kosintsev, P., Shidlovsky, F., Tong, H. -W., Tiunov, M. P., Vartanyan, S., Orlando, L., Corbett-Detig, R., MacPhee, R. D., Shapiro, B., Vershinina, A. O., Heintzman, P. D., Froese, D. G., Zazula, G., Cassatt-Johnstone, M., Dalén, L., Der Sarkissian, C., Dunn, S. G., Ermini, L., Gamba, C., Groves, P., Kapp, J. D., Mann, D. H., Seguin-Orlando, A., Southon, J., Stiller, M., Wooller, M. J., Baryshnikov, G., Gimranov, D., Scott, E., Hall, E., Hewitson, S., Kirillova, I., Kosintsev, P., Shidlovsky, F., Tong, H. -W., Tiunov, M. P., Vartanyan, S., Orlando, L., Corbett-Detig, R., MacPhee, R. D., and Shapiro, B.
- Abstract
The Bering Land Bridge (BLB) last connected Eurasia and North America during the Late Pleistocene. Although the BLB would have enabled transfers of terrestrial biota in both directions, it also acted as an ecological filter whose permeability varied considerably over time. Here we explore the possible impacts of this ecological corridor on genetic diversity within, and connectivity among, populations of a once wide-ranging group, the caballine horses (Equus spp.). Using a panel of 187 mitochondrial and eight nuclear genomes recovered from present-day and extinct caballine horses sampled across the Holarctic, we found that Eurasian horse populations initially diverged from those in North America, their ancestral continent, around 1.0–0.8 million years ago. Subsequent to this split our mitochondrial DNA analysis identified two bidirectional long-range dispersals across the BLB ~875–625 and ~200–50 thousand years ago, during the Middle and Late Pleistocene. Whole genome analysis indicated low levels of gene flow between North American and Eurasian horse populations, which probably occurred as a result of these inferred dispersals. Nonetheless, mitochondrial and nuclear diversity of caballine horse populations retained strong phylogeographical structuring. Our results suggest that barriers to gene flow, currently unidentified but possibly related to habitat distribution across Beringia or ongoing evolutionary divergence, played an important role in shaping the early genetic history of caballine horses, including the ancestors of living horses within Equus ferus. © 2021 John Wiley & Sons Ltd
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- 2021
25. Ancient horse genomes reveal the timing and extent of dispersals across the Bering Land Bridge
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Vershinina, A O, Heintzman, P D, Froese, D G, Zazula, G, Cassatt-Johnstone, M, Dalen, L, Sarkissian, C D, Dunn, S G, Ermini, L, Gamba, C, Groves, P, Kapp, J D, Mann, D H, Seguin-Orlando, A, Southon, J, Stiller, M, Wooller, M J, Baryshnikov, G, Gimranov, D, Scott, E, Hall, E, Hewitson, S, Kirillova, I, Kosintsev, P, Shidlovsky, F, Tong, H W, Tiunov, M P, Vartanyan, S, Orlando, L, Corbett-Detig, R, MacPhee, R D, Shapiro, B, Vershinina, A O, Heintzman, P D, Froese, D G, Zazula, G, Cassatt-Johnstone, M, Dalen, L, Sarkissian, C D, Dunn, S G, Ermini, L, Gamba, C, Groves, P, Kapp, J D, Mann, D H, Seguin-Orlando, A, Southon, J, Stiller, M, Wooller, M J, Baryshnikov, G, Gimranov, D, Scott, E, Hall, E, Hewitson, S, Kirillova, I, Kosintsev, P, Shidlovsky, F, Tong, H W, Tiunov, M P, Vartanyan, S, Orlando, L, Corbett-Detig, R, MacPhee, R D, and Shapiro, B
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- 2021
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26. Effects of dietary lipids on renal function of aged rats
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Valente Gamba C., Zeraib Caraviello A., Matsushita A., Alves G.M., Nunes da Silva L., Nascimento Gomes G., and Zaladek Gil F.
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aging ,lipids ,proteinuria ,renal function ,acid excretion ,canola oil ,fish oil ,Medicine (General) ,R5-920 ,Biology (General) ,QH301-705.5 - Abstract
Normal aging is accompanied by renal functional and morphological deterioration and dietetic manipulation has been used to delay this age-related decline. We examined the effects of chronic administration of diets containing 5% lipid-enriched diet (LD, w/w) on renal function of rats at different ages. Three types of LD were tested: canola oil, fish oil and butter. Mean systemic tail-cuff blood pressure and glycemia remained within the normal range whatever the age and the diet of the animals. Proteinuria began to rise from the 8th month in the groups ingesting LD, while in the control group it increased significantly (above 10 mg/24 h) only after the 10th month. With age, a significant and progressive decline in glomerular filtration rate (GFR) and renal plasma flow was observed in the LD groups but after 6 months of lipid supplementation, the decline in these parameters was more marked in the butter and fish oil groups. By the 18th month, the lowest GFR level was observed in the group ingesting the butter diet (2.93 ± 0.22 vs 5.01 ± 0.21 ml min-1 kg-1 in control, P
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- 2001
27. Population genetics and DNA preservation in ancient human remains from Eastern Spain
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Gamba, C., Fernández, E., Oliver, A., Tirado, M., Baeza, C., López-Parra, A.M., and Arroyo-Pardo, E.
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- 2008
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28. Y- STRs and forensic parameters in African populations
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Baeza, C., López Parra, A.M., Fernández, E., Gamba, C., Tirado, M., Mesa, M.S., and Arroyo-Pardo, E.
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- 2008
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29. Mitochondrial DNA genetic relationships at the ancient Neolithic site of Tell Halula
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Fernández, E., Ortiz, J.E., Torres, T., Pérez-Pérez, A., Gamba, C., Tirado, M., Baeza, C., López-Parra, A.M., Turbón, D., Anfruns, J., Molist, M., and Arroyo-Pardo, E.
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- 2008
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30. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
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Ridker PM, Everett BM, Thuren T, MacFadyen JG, Chang WH, Ballantyne C, Fonseca F, Nicolau J, Koenig W, Anker SD, Kastelein JJP, Cornel JH, Pais P, Pella D, Genest J, Cifkova R, Lorenzatti A, Forster T, Kobalava Z, Vida-Simiti L, Flather M, Shimokawa H, Ogawa H, Dellborg M, Rossi PRF, Troquay RPT, Libby P, Glynn RJ, Novo S, Krum H, Varigos J, Siostrzonek P, Sinnaeve P, Gotcheva N, Yong H, Urina-Triana M, Milicic D, Vettus R, Manolis AJ, Wyss F, Sigurdsson A, Fucili A, Veze I, Petrauskiene B, Salvador L, Klemsdal TO, Medina F, Budaj A, Otasevic P, Lainscak M, Seung KB, Commerford P, Donath M, Hwang JJ, Kultursay H, Bilazarian S, East C, Forgosh L, Harris B, Ligueros M, Bohula E, Charmarthi B, Cheng S, Chou S, Danik J, McMahon G, Maron B, Ning M, Olenchock B, Pande R, Perlstein T, Pradhan A, Rost N, Singhal A, Taqueti V, Wei N, Burris H, Cioffi A, Dalseg AM, Ghosh N, Gralow J, Mayer T, Rugo H, Fowler V, Limaye AP, Cosgrove S, Levine D, Lopes R, Scott J, Hilkert R, Tamesby G, Mickel C, Manning B, Woelcke J, Tan M, Manfreda S, Ponce T, Kam J, Saini R, Banker K, Salko T, Nandy P, Tawfik R, O’Neil G, Manne S, Jirvankar P, Lal S, Nema D, Jose J, Collins R, Bailey K, Blumenthal R, Colhoun H, Gersh B, Abreu M, Actis MV, Aiub J, Aiub F, Albisu J, Alvarisqueta A, Avalos V, Barreto M, Berli MA, Blumberg C, Bocanera M, Botta C, Bowen L, Budassi N, Buhlman S, Westberg JC, Carabajal T, Caruso G, Casala J, Cendali G, Coloma G, Berra FC, Cuneo C, Degennaro N, Dellasa M, Diaz M, Dos Santos P, Espinosa V, Facello A, Facello M, Farias E, Fernandez AA, Ferrari V, Pacora FF, Flores GS, Franco M, Gabito A, Viola HG, Garcia F, Garcia Duran R, Garcia Pinna J, Glenny J, Godoy Sanchez M, Grosse A, Guzman P, Hasbani E, Hominal M, Ibañez J, Jure H, Jure D, Vico ML, Liniado G, Luciardi H, Luquez H, Maehara G, Maffei L, Majul C, Mallagray M, Marinaro S, Martinez J, Massaccesi R, De Los Milagros Had M, Azize GM, Montana O, Montenegro E, Morell Y, Muntaner J, Navarrete S, Olmedo M, Paganini M, Paz S, Perez Manghi F, Piskorz D, Polato C, Recoaro R, Romano A, Salinger M, Sanchez A, Saravia MA, Sarjanovich R, Scaro G, Schiavi LB, Soler J, Tinnirello V, Tomassi A, Valle M, Vallejo MA, Venturini C, Marcela Wenetz LM, Yossen M, Zaidman C, Zalazar L, Zangroniz P, Amerena J, Brady L, Colquhoun D, Eccleston D, Ferreira-Jardim A, French J, Jayasinghe R, Mcintosh C, Ord M, Plotz M, Purnell P, Roberts-Thomson P, Schultz C, Shanahan T, Tan R, Taverner P, Turner F, Vibert J, Vorster M, William M, Youssef G, Bergler-Klein J, Brath H, Brodmann M, Fliesser-Goerzer E, Haider K, Heeren G, Hiden C, Mandic L, Paulweber B, Ploechl A, Prenner A, Steringer-Mascherbauer R, Strohner-Kaestenbauer H, Barbato E, Bouvy C, Briké C, Charlier F, Cools F, De Knijf K, De Wolf L, Delforge M, Deweerdt N, Gits F, Goffinet C, Hermans K, Hollanders G, Mestdagh I, Pirenne B, Servaes V, Simons N, Tahon S, Theunissen E, Van Genechten G, Vervoort G, Vissers C, Vranckx P, Vrolix M, Abib E Jr, Abrantes J, Araujo Fonseca M, Barbosa E, Barroso W, Barroso A, Bodanese L, Botelho R, Costa Amorim R, Da Costa F, Da Silva A, Da Silva O Jr, Da Silva D Jr, Ferreira Dos Santos T, Dos Santos F, Dos Santos A, Duda N, Feitosa G, Felario Junior GA, Ferraz R, Filho P, Fonseca A, Wanderley FF, Freitas E, Fucci F, Marengo Garcia De Carvalho L, Hernandez M, Hettwer Magedanz E, Julião K, Kormann A, Lameira A, Lima F, Lino E, Maia L, Manenti E, Marchi AL, Fischer SM, Michalaros Y, Moraes J Jr, Moreira L, Pagnan M, Pesce F, Pinheiro L, Rassi S, Reis G, Reis H, Resende I, Roel A, Ruschel K, Saporito W, Saraiva JF, Seroqui M, Silva R, Unterkircher B, Vicente C, Vieira N, Xavier JP, Zucchetti C, Angelova I, Dimitrov G, Genova D, Gospodinov K, Goudev A, Grigorova V, Hristova K, Makedonska JJ, Katova T, Kostov K, Lazov P, Manov E, Manukov I, Manukov D, Milanova M, Kabakchieva VM, Petrov D, Petrusheva T, Pramatarova I, Raev D, Runev N, Sirakova-Taseva A, Tisheva-Gospodinova S, Todorova A, Tzekova M, Yakovova S, Yanev T, Abulencia K, Arora S, Baker A, Bata IR, Beaudry M, Belle Isle J, Bilodeau N, Boivin MC, Bolduc H, Bourgeois S, Brons S, Cantor W, Chaussé I, Chhabra A, Chouinard G, Cleveland T, Dattani D, Deslongchamps F, Diodati J, Drouin K, Duchesne L, Fontaine S, d'Amours DG, Gervais B, Gosselin G, Graham J, Grover A, Gupta A, Haldane H, Hartleib M, Hickey L, Huynh T, Johnston J, Julien VE, Lachance P, Lake J, Lamontagne C, Lauzon C, Lepage S, Maheux K, Manyari D, Martin E, McPherson C, Mehta S, Michaud N, Kouz SM, Murphy G, OKeefe D, Otis R, Ouimet F, Pandey S, Peck C, Perkins L, Richert L, Robbins K, Robinson S, Cabau JR, Ross B, Roy C, Roy M, Roy A, Rupka D, Affaki GS, Saunders K, Savard D, Soucy D, St Amour E, Thiessen S, Vertes G, Vezina M, Vincelli G, Weisnagel SJ, Zadra R, Chen J, Chen Y, Dong X, Feng Y, Feng Z, Fu G, Han B, Hao Y, He Y, He Z, Hong T, Jia Z, Jiang T, Jiang J, Jiang X, Ke Y, Li Y, Li Z, Li W, Li X, Liu P, Liu Y, Liu B, Liu S, Liu L, Lu Z, Lv Y, Ma C, Ma G, Peng L, Qing L, Ren L, Sang X, Song M, Sun Z, Wang J, Wang Y, Wei J, Wu W, Wu J, Xu H, Yan J, Yang P, Yang K, Yao Z, Yaoqing H, Yuan Z, Zhai Z, Zhang J, Zhang Y, Zhao R, Zhou H, Accini Mendoza JL, Aparicio CV, Castillo T, Chaverra I, Conrado Y, Coronel J, Cotes C, Cuentas I, Cuervo A, Dussan MA, Echeverria L, Hernandez E, Ibarra J, Isaza D, Jimenez D, Lopez P, Manzur F, Mejia I, Mendoza Y, Molina DI, Patino JM, Rodriguez D, Rodriguez LM, Rodriguez SM, Sanchez Vallejo G, Luz Serrano H, Sotomayor A, Urina M, Vesga B, Yupanqui H, Akrap B, Busic N, Ciglenecki N, Cmrecnjak J, Fucak E, Gabor M, Jeric M, Jutrisa N, Kordic K, Planinc I, Popovic Z, Radeljic V, Sesto I, Sutalo K, Tusek S, Belohlavek J, Budkova J, Busak L, Capova L, Cech V, Cermak O, Coufalova Z, Cyprian R, Dedek V, Dedkova S, Ferkl R, Hanak P, Hanustiakova A, Homza M, Horackova K, Houra M, Iveta H, Kaiserova L, Kala P, Karel I, Kellnerova I, Koleckar P, Kreckova M, Krupicka J, Lorenc Z, Machova V, Malik J, Masarikova L, Matyasek I, Mikus M, Mikusova T, Ondrasik J, Otava M, Palubova L, Pavlickova L, Peterka M, Petrova I, Pokorna B, Povolny P, Radvan M, Reznakova S, Rickova Z, Roszkowska P, Rotreklova M, Samkova D, Skalicka H, Slechticka A, Sternthal P, Telekes P, Tesak M, Vesely P, Vesely J, Vins P, Vitovec M, Vodnansky P, Zidova M, Keba E, Laane E, Pool T, Randvee L, Ratnik E, Reimand M, Reinmets S, Rivis L, Siemann M, Stern M, Toom M, Vahula V, Apel T, Axthelm C, Ayasse D, Ayasse M, Baar M, Baeumer A, Bagi ES, Becker B, Binder A, Blankenberg S, Braun P, Johansen BB, Contzen C, Delfonso F, Denecke C, Dengler T, Donaubauer T, Eichinger G, Englmann E, Erhard M, Faghih M, Foerster A, Frankenstein L, Fuchs R, Furch G, Gaeb-Strasas B, Germann H, Giese C, Goette A, Gravenhorst-Muenter U, Haege R, Haenel T, Hagemann D, Hagenow A, Hanefeld M, Heider J, Heisters J, Hennig D, Hielscher S, Himpel-Boenninghoff A, Holscher A, Hornig M, Jeserich M, Kaczmarek N, Kanitz S, Kara YD, Khariouzov A, Kiefer R, Kiroglu K, Klamm M, Klein C, Korth-Wiemann B, Krapivsky A, Kuenzler J, Kuntzsch A, Landers B, Lappo M, Laube S, Leggewie S, Lehmann D, Lepp H, Lierse T, Lindner C, Luecke-Uzar M, Luedemann J, Marschke T, Maruzzo S, Mauersberger K, Maus O, Meinrich M, Meissner A, Moehring B, Muehlhaus J, Mueller S, Muenter KC, Muenzel T, Naumann R, Nebel J, Neumann J, Nuding S, Overhoff U, Papke B, Pencz I, Peter Y, Peukert AM, Radde I, Rau T, Regner S, Reichenbach D, Reimer D, Rinke A, Roettges R, Romanski A, Rummel R, Samer H, Sanuri M, Sarnighausen HE, Schäfer B, Scheibner T, Schermaul KH, Schindler A, Schlundt C, Schmidt E, Schmidt K, Schnabel A, Schoen N, Schorn K, Schroeder T, Schulenburg D, Schulz M, Schulze U, Schulze J, Schumacher M, Schwerin G, Schwerin M, Stadelmeier S, Stahl HD, Stahl A, Stockhausen J, Stockhausen G, Stoessel J, Stolze K, Stratmann M, Szymanowski N, Teschner AB, Teske A, Uecker C, Veit S, Voeller H, Walter I, Walter J, Walther I, Weber HG, Weimer J, Wichterich K, Wiebusch A, Willmerdinger M, Willner C, Winkelmann B, Winkler J, Wistuba T, Woehrle J, Wohnlich T, Wolf S, Woyczak D, Wrage P, Zirlik A, Anadiotis A, Chachalis G, Dermitzakis A, Kafarakis P, Kaldara E, Kolokathis F, Kostakou P, Lekakis J, Manolis A, Mantas I, Megalou A, Milkas A, Nanas J, Olympios CD, Patsilinakos S, Perperis A, Poulimenos L, Saloustros I, Tsioufis K, Tsorbatzoglou K, Vardas P, Zarifis I, Aguilar M, Arango JL, Borrayo NA, Corona V, Guerrero A, Guzman I, Haase F, De Krumbach L, Montenegro P, Munoz R, Munoz N, Paniagua A, Solares A, Vogel M, Anita S, Blazsek Z, Decsi K, Fulop T, Hangyal T, Hegedus V, Kalina A, Karakai H, Katona A, Kiss RG, Kovacs A, Laszlo Z, Lupkovics G, Medvegy M, Merkely B, Mihaly N, Nagy AC, Dékány JN, Nikoletta P, Noori E, Penzes J, Poor F, Sarszegi Z, Simay A, Simon J, Szakal I, Szatmarine V, Szocs A, Zilahi Z, Karsai XZ, Andersen K, Sigurdadottir E, Skuladottir F, Abdullakutty J, Abhaichand R, Abhyankar A, Agarwal DK, Aggarwal RK, Ahire N, Awasthi AK, Babu R, Bai A, Bali HK, Banker D, Bhadade S, Bisne V, Bohra P, Raghu C, Chauhan D, Chauhan H, Chavada J, Chaware G, Chella S, Chintala P, Dash D, Desai D, Devasia T, Dhanak R, Dobariya H, Dudhatra N, Duhan S, Fulwani M, Ghondale N, Ghosh S, Gohel P, Govindaraj D, Goyal B, Goyal S, Gundala AK, Gupta M, Hardas S, Iby M, Jagtap P, Jain A, Joshi U, Karpuram M, Kaur H, Khan A, Khan R, Kodem DR, Koeitti P, Kulkarni L, Kullal P, Kumar KS, Kumbla M, Latheef K, Lohkare M, Santosh MJ, Makhe B, Mandati M, Mehta A, Minocha G, Mittal A, Modi R, Mohan K, Oomman A, Pai R, Pai V, Palaniswami N, Pansheriya A, Parekh N, Patel J, Patel R, Patole T, Praveen M, Radhakrishnan V, Rajan B A, Rajasekhar D, Rao M, Rao MB, Rao NM, Rathnavel S, Rathore A, Rathore SRS, Rawat S, Reddy NC, Sarma R, Sathe S, Shah J, Shaikh P, Sharma K, Sharma S, Sharma T, Shetty P, Sidhu G, Singh V, Sohi GS, Srinath VS, Raju SS, Taran A, Thakkar B, Velusamy K, Vijan V, Vora V, Vuriya AK, Agosta GF, Antonicelli R, Ardissino D, Argiolas G, Baldin MG, Benedetti G, Berti 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Hodnett P, Hoffman M, Hogan C, Holmes Z, Rees DH, Hotchkiss D, Huang P, Humbert J, Hutchens E, Iachini K, Ibarra M, Igbokidi O, Ilahi T, Imbrognio M, Ipp E, Iteld B, Jacques G, Jafri A, Jafry B, Jardula M, Jefferson D, Jenkins R, Johnson E, Johnson J, Jones S, Kawahara M, Kelehan S, Kelly R, Kendall T, Kereiakes D, Khan M, Khan S, Kick J, Kimmel M, King T, King A, Kirkland S, Kissel S, Kitchens D, Klein P, Klugherz B, Korban E, Koren M, Korte M, Kostis J, Kotek L, Kozak M, Kreutter F, Kusnick B, Labovitz R, Lail J, Lamance J, Lamas G, Lambert J, Lambert C, Landzberg J, Langdon J, Lavoie W, Ledger G, Lee T, Lee K, Lehman R, Leimbach W, Lennard M, Lepor N, Lester F, Levin P, Levinson L, Lewis D, Lillo J, Link L, Long C, Longaker R, Lorch G, Lucksinger G, Lynd S, Rhudy JM, Madder R, Magness K, Maheshwari A, Alan A, Malek M, Maletz L, Malhotra V, Malhotra S, Mandviwala M, Mani CK, Manuel J, Marchelletta N, Marshall L, Marsters M, Martin L, Martinez E, Mavromatis K, Maynard R, Mays M, Mays B, Mbulaiteye A, Mcalister R, Mccoy C, Mccrary D Jr, Mccullough-O'Brien H, Mcdonald M, Mcgill J, Mcgrew F, Mckenzie C, Mclaurin B, Mclellan BA, Mcneil D, Mcneill R, Mehrle A, Melbie K, Melliza T, Messina T, Meyer R, Michel K, Mikdadi G, Miller C, Miller R, Miller A, Miller G, Miller W, Mitchell J, Moats DJR, Mody F, Moffat J, Molk B, Molter D, Monroe T, Montero H, Montgomery R, Mookherjee D, Moran J, Moriarty P, Morrison J, Morton D, Moshayedi P, Mosley J, Moustafa M, Munshi K, Murray A, Mustafa J, Nadar V, Naidu R, Nalley J, Navy S, Neil L, Neutel JM, Niblack P, Nicely V, Nicolai M, Nijmeh G, Nikas A, Nikyar A, Nixon S, Norman L, Noto G, Nour K, Nugent A, Ocman B, Odegard A, Olsen S, Ortiz-Carrasquillo R, Ossino N, Paez H, Palchick B, Paliwal Y, Pannell R, Parfait V, Partridge J, Patel B, Patel R, Patel M, Patel S, Paysor C, Pena A, Pereira S, Perez M, Perez A, Perkins H, Perry B, Peters P, Phillippi C, Phillips A, Phillips A, Piacente R, Pintado M, Pish R, Pitt W, Poling T, Pomposini D, Poock J, Potts J, Poudrier R, Prior J, Pritchard C, Purighalla R, Quddusi K, Quinones J, Quinton D, Radin M, Radojcsics B, Rajput B, Rama B, Ramos M, Rauch R, Raynes K, Reber AM, Reddy J, Reeves M, Reilly K, Renaud K, Resnick H, Reyes R, Richardson M, Riethof M, Riser J, Rodero M, Rodriguez Araya E, Roper L, Rozeman P, Ruder D, Runquist L, Sack G, Saint-Jacques H, Salfity M, Sall N, Sam K, Samal A, Sanchez D, Santiago J Jr, Savignano C, Saylor R, Scheffel M, Schifferdecker B, Schindler E, Schneider P, Schneider R, Schnitzler R, Schrager B, Schwartz A, Scott R, Seals A, Shah AV, Shah A, Shatsky K, Shayani S, Shealy N, Sheets L, Shelley J, Shepard P, Shetty S, Silver K, Simon M, Singh K, Singh N, Sizemore BC, Skatrud L, Slayton C, Slimak V, Sloane G, Smallwood B, Smith P, Smith M, Smith T, Smith G, Smith B, Smith W, Smith M, Smith J, Smith J, Soca Y, Sofley C, Sopko K, Sosa-Padilla M, Sotolongo R, Sprinkle B, Srivastava S, Starzec M, Steinhoff J, Stelly L, Stinson J, Stoddard M, Stoltz S, Stone B, Stover T, Strain J, Strugatsky S, Stys T, Suleman A, Sullivan P, Tamez W, Tandon N, Teltser M, Terry PS, Terry K, Tessmar C, Thekkoott D, Thomas D, Thomas DM, Thompson E, Thompson J, Thornton A, Tjaden T, Tobias C, Topper J, Tran A, Treasure C, Trenkamp P, Trevino M, Tsou L, Tuholske C, Uy W, Vahtel M, Vaid B, Valenzuela M, Vance A, Vandam J, Vanhecke T, Vanness WC III, Vargas R, Vaz S, Vazquez Tanus J, Veerina K, Vega J, Vento A, Vijay N, Voelker F, Vogt E, Vold D, Vora K, Wade RD, Wadell C, Waksman R, Walker K, Walker K, Wallace K, Warren M, Washam M, Watson B, Webel R, Wells T, West M, Whitaker J, White J, White C, White A, White A, Wilhoit G, Wilkins M, Willingham K, Wilson S, Wilson V, Wise J, Woodall S, Woods A, Wright J, Wu J, Xu ZJ, Yarows S, Young A, Younis L, Zarate J, Zebrack J, Zhang W, Zieve F, Zineldine A, Ridker, P. M., Everett, B. M., Thuren, T., Macfadyen, J. G., Chang, W. H., Ballantyne, C., FONSECA E PIRES, CARLOS EDUARDO, Nicolau, J., Koenig, W., Anker, S. D., Kastelein, J. J. P., Cornel, J. H., Pais, P., Pella, D., Genest, J., Cifkova, R., Lorenzatti, A., Forster, T., Kobalava, Z., Vida-Simiti, L., Flather, M., Shimokawa, H., Ogawa, H., Dellborg, M., Rossi, P. R. F., Troquay, R. P. T., Libby, P., Glynn R., J, CANTOS Trial, Group, Perrone, Filardi, P, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, ACS - Pulmonary hypertension & thrombosis, and ACS - Atherosclerosis & ischemic syndromes
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0301 basic medicine ,030204 cardiovascular system & hematology ,law.invention ,0302 clinical medicine ,c-reactive protein ,Randomized controlled trial ,law ,Cardiovascular Disease ,middle aged ,double-blind method ,antibodies ,Myocardial infarction ,humans ,Stroke ,interleukin-1beta ,biology ,Antibodies, Monoclonal ,drug ,General Medicine ,Lipid ,Aged ,anti-inflammatory agents ,monoclonal ,humanized ,atherosclerosis ,cardiovascular diseases ,dose-response relationship ,female ,incidence ,infections ,lipids ,male ,myocardial infarction ,neutropenia ,secondary prevention ,stroke ,Anti-Inflammatory Agent ,aged ,Editorial ,Atherosclerosi ,Monoclonal ,Human ,medicine.drug ,medicine.medical_specialty ,Neutropenia ,Antibodies, Monoclonal, Humanized ,Infections ,Placebo ,antibodies, monoclonal ,dose-response relationship, drug ,infection ,medicine (all) ,03 medical and health sciences ,Internal medicine ,medicine ,Dose-Response Relationship, Drug ,business.industry ,Antiinflammatory Therapy, Canakinumab, for Atherosclerotic Disease ,C-reactive protein ,medicine.disease ,Surgery ,Canakinumab ,030104 developmental biology ,biology.protein ,business - Abstract
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.)
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- 2017
31. Seroconversion of 2009 pandemic influenza A (H1N1) vaccination in kidney transplant patients and the influence of different risk factors
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Azevedo, L. S., Gerhard, J., Miraglia, J. L., Precioso, A. R., Tavares Timenetsky, M. dC.S., Agena, F., Gamba, C., Shikanai Yasuda, M. A., David-Neto, E., and Pierrotti, L.
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- 2013
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32. Malakoplakia after renal transplantation in the current era of immunosuppressive therapy: case report and literature review
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Leão, C. A., Duarte, M. I.S., Gamba, C., Ramos, J. F., Rossi, F., Galvão, M. M., David-Neto, E., Nahas, W., Shikanai-Yasuda, M. A., and Pierrotti, L. C.
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- 2012
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33. The effect of urea and pig slurry fertilization on denitrification, direct nitrous oxide emission, volatile fatty acids, water-soluble carbon and anthrone-reactive carbon in maize-cropped soil from the Po plain (Modena, Italy)
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Arcara, P. G., Gamba, C., Bidini, D., and Marchetti, R.
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- 1999
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34. Argentinean Public Umbilical Cord Blood Bank and Its AABB Accreditation Process: AP3
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Kuperman, S, Gamba, C, Oknaian, S, Martinez, G, Marcos, M, Perez, G, Remesar, M C, and del Pozo, A E
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- 2011
35. Detection of CMV infection in the Argentinean Public Cord Blood Bank: SP474
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Remesar, M C, Fernández, C, Gamba, C, Suris, A, and del Pozo, A E
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- 2011
36. Significance of Inconclusive Results on T. cruzi Antibody Assays in Blood Donors from a Highly Endemic Region of Argentina: SP479
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Remesar, M C, Sabino, E C, Gamba, C, Busch, M P, Tobler, L H, Puppo, M, Ridolfi, M A, Kupperman, S, and Del Pozo, A E
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- 2009
37. Unrelated cord blood transplantation and reduced-intensity conditioning regimen for graft failure in a child with Major Histocompatibility Complex class II deficiency
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Bonduel, M, Staciuk, R, Figueroa, C, Oleastro, M, Gamba, C, Rossi, J, and del Pozo, A
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- 2009
38. Strongyloides stercoralis hyperinfection after allogeneic stem cell transplantation
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Dulley, F L, Costa, S, Cosentino, R, Gamba, C, and Saboya, R
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- 2009
39. ANKLE ARTHRODESIS IN HIGH RISK PATIENTS. A RADIOGRAPHIC AND CLINICAL STUDY.
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Molloy, A P, Myerson, M S, Gamba, C E, Sealey, R, Garcia, F, and Jeng, C
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- 2009
40. RANGE OF MOTION OF THE HINDFOOT FOLLOWING ANKLE ARTHRODESIS: A PROSPECTIVE ANALYSIS.
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Sealey, R J, Myerson, M S, Molloy, A P, Gamba, C E, and Jeng, C
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- 2009
41. Evaluation of Tests for Trypanosoma cruzi Antibodies in Blood Donors from Argentinean Endemic Area: SP491
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Remesar, M C, Sr., Colaianni, I, Jr., Gamba, C, Jr., Puppo, M, Sr., Ridolfi, M A, Sr., Sartor, P, Jr., Leguizamón, S, Sr., and Del Pozo, A, Sr.
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- 2007
42. Rehabilitation: the Cinderella of neurological research? A bibliometric study
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Tesio L., Gamba C., Capelli A., and Franchignoni F. P.
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- 1995
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43. Impact of tillage practices on seasonal nitrate dynamics, leaching and microbial activity in a crop rotation
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Papini, R., primary, Gamba, C., additional, Piovanelli, C., additional, and Brandi, G., additional
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- 2002
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44. UMBILICAL CORD BLOOD BANKING: ARGentINAS UNRELATED PROGRAM: P-542
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Gamba, C., Marcos, A., Casini, S., Ramos, E., Bernasconi, A., Marcos, C. Y., Theiler, G., Casimir, L., and Del Pozo, E.
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- 2006
45. HCV INFECTION IN MULTI-TRANSFUSED AND PUTATIVE IMMUNO-COMPROMISED PATIENTS IN ARGENTINA: P-071
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Remesar, M. C.R., Gamba, C., Oknaian, S., Batalla, M., and Del Pozo, A. E.
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- 2006
46. The Hemoglobin Colour Scale: A Suitable Hb Screening Method for Blood Donors?
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Kuperman, S L, Gamba, C, Virgilio, S, Cilurzo, P, De Souza Frade, G, Izaguirre, S, and Del Pozo, A E
- Published
- 2003
47. Evaluation of Mesenchymal Cells (MSC) and Dapsone for the Treatment of Dermonecrotic Wounds Caused by Loxosceles laeta Venom in Rabbits
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Soto-Blanco B, Goes A, Botelho Af, Cassali G, Melo M, Martins G, Bicalho A, Gamba C, Chavez-Olortegui C, Duarte C, and Oliveira M
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business.industry ,Mesenchymal stem cell ,Medicine ,Venom ,Pharmacology ,Dapsone ,business ,medicine.disease ,Loxoscelism ,medicine.drug - Abstract
We studied the efficacy of mesenchymal stem cells (MSC), either alone or associated with dapsone (DAP) in the treatment of dermonecrotic wounds caused by Loxosceles laeta spider venom. Twenty-five male adult rabbits were distributed into five groups, of which four groups received an intradermal injection of 20 μg of L. laeta venom and only one received ultrapure water (negative control). After 4 hours, each group that received venom, was treated with MSC, DAP, MSC + DAP and Phosphate-buffered saline – PBS (positive control). Photographic records were made for analysis of the wound area evolution by morphometry. Twelve days after treatment, the skin samples around the lesion were removed for subsequent histological analysis. Concerning the rate of wound contraction, we observed that DAP showed the best percentage of contraction at day 3. In the treatments using MSCs, a negative value of wound contraction was observed for the isolated MSCs, as well as a lower contraction value for the association of the MSC + DAP when compared to PBS group. Histopathological analysis showed diminished tissue lesion and less intense inflammation in MSCs and DAP groups. This could indicated potential use of stem cells in regenerative therapies after loxoscelic accidents.
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- 2018
48. Preliminary results of mitochondrial DNA sequence variation in Spanish Pyrenean populations
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López-Parra, A.M., Fernández, E., Baeza, C., Gamba, C., Tirado, M., Gusmão, L., Mesa, M.S., and Arroyo-Pardo, E.
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- 2009
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49. 56. Ultrasound (US) features of Charcot-Marie-Tooth disease type 1 (HMSN TYPE I)
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Sartucci, F., primary, Bocci, T., additional, Di Rollo, A., additional, Del Gamba, C., additional, Bartolotta, M., additional, Barloscio, D., additional, Parenti, L., additional, and Santin, M., additional
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- 2017
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50. Surveillance of severe cutaneous drug reactions: Experience REACT-Lombardia [Sorveglianza di reazioni gravi cutanee da farmaco: L'esperienza REACT-Lombardia]
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Gamba, C, Schroeder, J, Citterio, A, Cazzaniga, S, Rivolta, A, Vighi, G, Lorini, F, Gamba C, Schroeder J, Citterio A, Cazzaniga S, Rivolta AL, Vighi G, Lorini F, Gamba, C, Schroeder, J, Citterio, A, Cazzaniga, S, Rivolta, A, Vighi, G, Lorini, F, Gamba C, Schroeder J, Citterio A, Cazzaniga S, Rivolta AL, Vighi G, and Lorini F
- Abstract
Adverse drug reactions affecting the skin have particular relevance as they may cause significant mortality and a possible modification of the benefit/risk profile of the concerned drug. The following entities are of special importance: Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), acute generalized exanthematous pustulosis (AGEP) and drug rash with eosinophilia and systemic symptoms (DRESS). On the above mentioned reactions we focused our surveillance programme in the Lombardy region, the REACT-Lombardia project. The REACT registry involved 22 hospital-based dermatological centres, collecting, from April 2009 up to March 2014, a total of 72 cases of SJS-TEN, 17 cases of AGEP and 9 cases of DRESS. Allopurinol was the drug associated with the largest number of cases of SJS/TEN (21 cases) followed by paracetamol (8 cases), levofloxacine (6 cases) and carbamazepine (4 cases). The risk for specific drug exposures was estimated by employing drug utilization data expressed as Defined Daily Doses (DDD). Mortality rate from SJS-TEN was 21%. Together with the registry, a "hub and spoke" clinical network for the management of severe cutaneous reactions was established with the Burn Unit of Niguarda Ca' Granda Hospital as the reference center for the most critical patients.
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- 2014
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