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313 results on '"Galajda, Peter"'

3. Microfluidic Ecology Unravels the Genetic and Ecological Drivers of T4r Bacteriophage Resistance in E. coli: Insights into Biofilm-Mediated Evolution

Author

Austin, Robert, primary, Nagy, Krisztina, additional, Valappil, Sarshad, additional, Phan, Trung, additional, Li, Shengkai, additional, Dér, László, additional, Morris, Ryan, additional, Bos, Julia, additional, Winslow, Sophia, additional, Galajda, Peter, additional, and Rákhely, Gábor, additional

Published
2024
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5. Left Ventricular and Atrial Deformation in Patients with Acute Decompensated Heart Failure: A Pilot Study.

Author

Jurica, Jakub, Péč, Martin Jozef, Cingel, Marek, Bolek, Tomáš, Barbierik Vachalcová, Marianna, Horná, Simona, Galajda, Peter, Mokáň, Marián, and Samoš, Matej

Subjects
GLOBAL longitudinal strain, SPECKLE tracking echocardiography, VENTRICULAR ejection fraction, HEART failure, LEFT heart atrium
Abstract

Aims: The aims of this study were to compare global longitudinal strain of the left ventricle (LV-GLS) and reservoir strain of the left atrium (R-LAS) values between patients with acute decompensation of chronic heart failure (HF) and a control group. Methods: Sixteen patients admitted to our ward for acute decompensation of HF were enrolled in this study. Transthoracic echocardiography (TTE) with two-dimensional speckle-tracking analysis (2D ST) was performed in each patient. The patients were divided into two subgroups according to the value of left ventricular ejection fraction (EF) using a cut-off value of ≤40% to distinguish heart failure with reduced ejection fraction (HFrEF) from heart failure with preserved ejection fraction (HFpEF). The control group consisted of 16 individuals without a history of cardiovascular disease, each of whom underwent 2D ST analysis as well. Results: We found that LV-GLS and R-LAS were significantly lower in both the HFrEF and HFpEF subgroups in comparison with the control group (LV-GLS: −13.4 ± 4.7% vs. −19.7 ± 2.5%, p ˂ 0.05; R-LAS: +12.2 ± 6.9% vs. +40.3 ± 7.4%, p ˂ 0.05). Furthermore, there was a significant difference in LV-GLS (−9.6 ± 3.2% vs. −15.2 ± 4.3%, p ˂ 0.05) but not in R-LAS (+13.7 ± 8.6% vs. +11.4 ± 6.2%) between the HFrEF and HFpEF subgroups. Conclusions: Our study demonstrated a significant difference in LV-GLS and R-LAS in all enrolled HF patients compared to the control group. There was also a significant difference in LV-GLS between the HFrEF and HFpEF subgroups. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Dimensionality constraints of light induced rotation

Author

Oroszi, László, Búzás, András, Galajda, Péter, Kelemen, Lóránd, Mathesz, Anna, Vicsek, Tamás, Vizsnyiczai, Gaszton, and Ormos, Pál

Subjects
Physics - Optics
Abstract

We have studied the conditions of rotation induced by collimated light carrying no angular momentum. Objects of different shapes and optical properties were examined in the nontrivial case where the rotation axis is perpendicular to the direction of light propagation. This geometry offers important advantages for application as it fundamentally broadens the possible practical arrangements to be realised. We found that collimated light cannot drive permanent rotation of 2D or prism-like 3D objects (i.e. fixed cross-sectional profile along the rotation axis) in the case of fully reflective or fully transparent materials. Based on both geometrical optics simulations and theoretical analysis, we derived a general condition for rotation induced by collimated light carrying no angular momentum valid for any arrangement: Permanent rotation is not possible if the scattering interaction is two-dimensional and lossless. In contrast, light induced rotation can be sustained if partial absorption is present or the object has specific true 3D geometry. We designed, simulated, fabricated, and experimentally tested a microscopic rotor capable of rotation around an axis perpendicular to the illuminating light., Comment: 5 pages, 5 figures

Published
2015
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9. Role of Platelets in Rheumatic Chronic Autoimmune Inflammatory Diseases.

Author

Péč, Martin Jozef, Jurica, Jakub, Péčová, Monika, Benko, Jakub, Sokol, Juraj, Bolek, Tomáš, Samec, Marek, Hurtová, Tatiana, Galajda, Peter, Samoš, Matej, and Mokáň, Marián

Subjects
AUTOIMMUNE diseases, BLOOD platelets, SYSTEMIC lupus erythematosus, INFLAMMATION, THERAPEUTICS
Abstract

Platelets are essential in maintaining blood homeostasis and regulating several inflammatory processes. They constantly interact with immune cells, have immunoregulatory functions, and can affect, through immunologically active substances, endothelium, leukocytes, and other immune response components. In reverse, inflammatory and immune processes can activate platelets, which might be significant in autoimmune disease progression and arising complications. Thus, considering this interplay, targeting platelet activity may represent a new approach to treatment of autoimmune diseases. This review aims to highlight the role of platelets in the pathogenic mechanisms of the most frequent chronic autoimmune inflammatory diseases to identify gaps in current knowledge and to provide potential new targets for medical interventions. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Role of Platelets in Rheumatic Chronic Autoimmune Inflammatory Diseases

Author

Péč, Martin Jozef, additional, Jurica, Jakub, additional, Péčová, Monika, additional, Benko, Jakub, additional, Sokol, Juraj, additional, Bolek, Tomáš, additional, Samec, Marek, additional, Hurtová, Tatiana, additional, Galajda, Peter, additional, Samoš, Matej, additional, and Mokáň, Marián, additional

Published
2023
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16. The Anti-Thrombotic Effects of PCSK9 Inhibitors

Author

Péč, Martin Jozef, primary, Benko, Jakub, additional, Jurica, Jakub, additional, Péčová, Monika, additional, Samec, Marek, additional, Hurtová, Tatiana, additional, Bolek, Tomáš, additional, Galajda, Peter, additional, Péč, Martin, additional, Samoš, Matej, additional, and Mokáň, Marián, additional

Published
2023
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25. COVID-19 and the Response to Antiplatelet Therapy

Author

Bolek, Tomáš, primary, Samoš, Matej, additional, Jurica, Jakub, additional, Stančiaková, Lucia, additional, Péč, Martin Jozef, additional, Škorňová, Ingrid, additional, Galajda, Peter, additional, Staško, Ján, additional, Mokáň, Marián, additional, and Kubisz, Peter, additional

Published
2023
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35. Diabetic Heart Failure with Preserved Left Ventricular Ejection Fraction: Review of Current Pharmacotherapy

Author

Benko, Jakub, Samoš, Matej, Bolek, Tomáš, Prídavková, Dana, Jurica, Jakub, Péč, Martin Jozef, Galajda, Peter, and Mokáň, Marián

Subjects
Article Subject
Abstract

Diabetes is associated with several diabetic-related abnormalities which increase the risk of onset or worsening of heart failure. Recent studies showed that the majority of diabetic patients present with heart failure with preserved ejection fraction (HFpEF), and the prevalence of HFpEF in diabetics is alarming. Moreover, outcomes in HFpEF are poor and could be compared to those of heart failure with reduced ejection fraction (HFrEF), with 1-year mortality ranging between 10 and 30%. In contrast to HFrEF, there is very limited evidence for pharmacologic therapy in symptomatic patients with preserved ejection fraction, and therefore, the optimal selection of treatment for diabetic HFpEF remains challenging. This narrative review article summarizes the currently available data on the pharmacological treatment of HFpEF in patients with diabetes.

Published
2022
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43. Arteria lusoria - a rare cause of dysphagia or a common accidental finding?

Author

Péč, Martin Jozef, primary, Kučeríková, Monika, additional, Grilusová, Kristína, additional, Slobodníková, Veronika, additional, Strýčková, Alena, additional, Beliančinová, Monika, additional, Sokol, Juraj, additional, Samoš, Matej, additional, Galajda, Peter, additional, Zeleňák, Kamil, additional, and Mokáň, Marián, additional

Published
2021
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45. Apixaban

Author

Grilusová, Kristína, primary, Bolek, Tomáš, additional, Škorn[Combining Caron]ová, Ingrid, additional, Stančiaková, Lucia, additional, Mikušová, Veronika, additional, Kubisz, Peter, additional, Galajda, Peter, additional, Staško, Ján, additional, Samoš, Matej, additional, and Mokán[Combining Caron], Marián, additional

Published
2021
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