345 results on '"Gailus-Durner, Valérie"'
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2. Implication of transcription factor FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT)
3. Co-expression of prepulse inhibition and Schizophrenia genes in the mouse and human brain
4. AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease
5. Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease
6. GPR101 loss promotes insulin resistance and diet-induced obesity risk
7. Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome
8. Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model
9. Monitoring longitudinal disease progression in a novel murine Kit tumor model using high-field MRI
10. Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice
11. Costs of Implementing Quality in Research Practice
12. Creld1 regulates myocardial development and function
13. In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria
14. A mouse model for intellectual disability caused by mutations in the X-linked 2′‑O‑methyltransferase Ftsj1 gene
15. Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice
16. Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo
17. The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation
18. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity
19. Big data in large-scale systemic mouse phenotyping
20. Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice
21. Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice
22. Costs of Implementing Quality in Research Practice
23. Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse
24. Offspring born to influenza A virus infected pregnant mice show increased vulnerability to viral and bacterial infections in early life
25. Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction
26. A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia
27. Mouse Genetics and Metabolic Mouse Phenotyping
28. The German Mouse Clinic – Running an Open Access Platform
29. INFRAFRONTIER: a European resource for studying the functional basis of human disease
30. Mildly compromised tetrahydrobiopterin cofactor biosynthesis due to Pts variants leads to unusual body fat distribution and abdominal obesity in mice
31. Mutations within the cGMP-binding domain of CNGA1 causing autosomal recessive retinitis pigmentosa in human and animal model
32. Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis
33. Modeling hepatic osteodystrophy in Abcb4 deficient mice
34. An ENU Mutagenesis-Derived Mouse Model with a Dominant Jak1 Mutation Resembling Phenotypes of Systemic Autoimmune Disease
35. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
36. High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice
37. Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice
38. The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability
39. Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain
40. High-throughput phenotypic assessment of cardiac physiology in four commonly used inbred mouse strains
41. MiR-34a deficiency accelerates medulloblastoma formation in vivo
42. Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project
43. Innovations in phenotyping of mouse models in the German Mouse Clinic
44. Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients
45. Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice
46. Rapamycin extends murine lifespan but has limited effects on aging
47. Experimental data of a single promoter can be used for in silico detection of genes with related regulation in the absence of sequence similarity
48. Systemic First-Line Phenotyping
49. Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines
50. Sum1 and Hst1 repress middle sporulation‐specific gene expression during mitosis in Saccharomyces cerevisiae
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