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19 results on '"Gail, M.H."'

1. Sleep Health and the Oral Microbiome

Author

Dalton, K., primary, Lee, M., additional, Liao, L.M., additional, Gail, M.H., additional, Shi, J., additional, Sinha, R., additional, Abnet, C.C., additional, London, S.J., additional, and Vogtmann, E., additional

Published
2024
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3. Case-control studies with errors in covariates

Author

Carroll, R.J., Gail, M.H., and Lubin, J.H.

Subjects
Analysis of covariance -- Research, Regression analysis -- Models, Nonparametric statistics -- Asymptotic theory, Mathematics
Abstract

Methods for estimating the parameters of a prospective logistic model with dichotomous response D and arbitrary covariates X are devised for case-control studies where the covariate measurements are with error. It is assumed that the true covariates X and error-prone measurements W are provided by a random fraction of the cases and controls while another random sampling provides only the error-prone measurements. The methods used in the study include the pseudolikelihood approach, rare disease approximations with nondifferential error and the approximate logistic regression techniques.

Published
1993

8. Helicobacter pylori infection in rural China: demographic, lifestyle and environmental factors

Author

Brown, L.M., Thomas, T.L., Ma, J-L., Chang, Y-S., You, W-C., Liu, W-D., Zhang, L., Pee, D., and Gail, M.H.

Abstract

Background Although Helicobacter pylori is one of the most common human bacterial infections worldwide, its mode of transmission is unclear.
Methods To investigate possible associations between H. pylori infection and demographic, lifestyle, and environmental factors in a rural Chinese population, a cross-sectional survey was administered to 3288 adults (1994 seropositive, 1019 seronegative, 275 indeterminate) from 13 villages in Linqu County, Shandong Province, China.
Results Helicobacter pylori prevalence was elevated for: infrequent handwashing before meals (OR = 1.7, 95% CI: 1.0-3.0), crowding (i.e. sharing a bed with >2 people [OR = 2.3, 95% CI: 1.3-4.2]), washing/bathing in a pond or ditch (OR = 1.5, 95% CI: 1.0-2.4), and medium (OR = 1.6, 95% CI: 1.3-2.0) and low (OR = 2.3, 95% CI: 1.9-2.9) compared to high village education level, and reduced for never being married or divorced (OR = 0.4, 95% CI: 0.2-1.0). There was also a suggestion that source of drinking water, especially water from a shallow village well might be related to H. pylori seropositivity. There was no evidence of an association between H. pylori prevalence and alcohol or tobacco use, raw fruit and vegetable intake, or individual social class measures.
Conclusions The results of this study suggest that person-to-person transmission is the most plausible route of H. pylori infection in this rural Chinese population, but waterborne exposures deserve further investigation.

Published
2002

9. A placebo-controlled randomized double-blind study of adjuvant intrapleural BCG in patients with resected T1N0, T1N1, or T2N0 squamous cell carcinoma, adenocarcinoma, or large cell carcinoma of the lung: LCSG Protocol 771

Author

Gail, M.H.

Subjects
Care and treatment, Usage, Research, Vaccines -- Research -- Usage, Lung cancer -- Care and treatment -- Research, BCG -- Usage -- Research, Adjuvant chemotherapy -- Research -- Usage, Cancer -- Adjuvant treatment, BCG vaccines -- Usage -- Research
Abstract

According to the author's abstract of an article published in Chest, 'This article reviews the design and findings of LCSG Protocol 771, a randomized double-blind comparison of postoperative adjuvant intrapleural [...]

Published
1995

13. Use of observational data, including surveillance studies, for evaluating AIDS therapies

Author

Gail, M.H.

Subjects
AIDS (Disease) -- Research, Clinical trials -- Evaluation
Abstract

Gail, M.H. "Use of Observational Data, Including Surveillance Studies, for Evaluating AIDS Therapies." Statistics in Medicine, November 15, 1996;15(21-22):2273-2288. According to the author's abstract of an article published in Statistics [...]

Published
1996

19. Associations between Biomarkers of Exposure and Lung Cancer Risk among Exclusive Cigarette Smokers in the Golestan Cohort Study

Author

Neal D. Freedman, Mitchell H. Gail, Antonia M. Calafat, Qian Wang, Gholamreza Roshandel, Lanqing Wang, Brian L. Rostron, Víctor R. De Jesús, Hossein Poustchi, Paolo Boffetta, Cindy M. Chang, Sapna K. Thakur, Jun Feng, Julianne Cook Botelho, Baoyun Xia, Reza Malekzadeh, Meredith S. Shiels, Yuesong Wang, Deepak Bhandari, Akram Pourshams, Joanne T. Chang, Benjamin C. Blount, Arash Etemadi, Maki Inoue-Choi, Jia Wang, Paul Brennan, Christian C. Abnet, Rostron B.L., Wang J., Etemadi A., Thakur S., Chang J.T., Bhandari D., Botelho J.C., De Jesus V.R., Feng J., Gail M.H., Inoue-Choi M., Malekzadeh R., Pourshams A., Poustchi H., Roshandel G., Shiels M.S., Wang Q., Wang Y., Xia B., Boffetta P., Brennan P., Abnet C.C., Calafat A.M., Wang L., Blount B.C., Freedman N.D., and Chang C.M.

Subjects
Male, medicine.medical_specialty, Lung Neoplasms, Nitrosamines, Health, Toxicology and Mutagenesis, Nitrosamine, tobacco, Article, Odds, Cohort Studies, Nicotine, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Humans, 030212 general & internal medicine, Lung cancer, Smoker, Smokers, business.industry, Incidence (epidemiology), Public Health, Environmental and Occupational Health, Opium, Tobacco Products, medicine.disease, Lung Neoplasm, lung cancer, Case-Control Studies, 030220 oncology & carcinogenesis, Carcinogens, Disease risk, Biomarker (medicine), biomarker, Medicine, Cohort Studie, Case-Control Studie, business, Biomarkers, Carcinogen, Human, medicine.drug, Cohort study
Abstract

Biomarkers of tobacco exposure are known to be associated with disease risk but previous studies are limited in number and restricted to certain regions. We conducted a nested case–control study examining baseline levels and subsequent lung cancer incidence among current male exclusive cigarette smokers in the Golestan Cohort Study in Iran. We calculated geometric mean biomarker concentrations for 28 matched cases and 52 controls for the correlation of biomarker levels among controls and for adjusted odds’ ratios (ORs) for lung cancer incidence by biomarker concentration, accounting for demographic characteristics, smoking quantity and duration, and opium use. Lung cancer cases had higher average levels of most biomarkers including total nicotine equivalents (TNE-2), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and 3-hydroxyfluorene (3-FLU). Many biomarkers correlated highly with one another including TNE-2 with NNAL and N-Acetyl-S-(2-cyanoethyl)-L-cysteine (2CYEMA), and N-Acetyl-S-(4-hydroxy-2-buten-1-yl)-L-cysteine (t4HBEMA) with N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine (3HMPMA) and N-Acetyl-S-(4-hydroxy-2-methyl-2-buten-1-yl)-L-cysteine (4HMBEMA). Lung cancer risk increased with concentration for several biomarkers, including TNE-2 (OR = 2.22, 95% CI = 1.03, 4.78) and NNN (OR = 2.44, 95% CI = 1.13, 5.27), and estimates were significant after further adjustment for demographic and smoking characteristics for 2CYEMA (OR = 2.17, 95% CI = 1.03, 4.55), N-Acetyl-S-(2-carbamoylethyl)-L-cysteine (2CAEMA) (OR = 2.14, 95% CI = 1.01, 4.55), and N-Acetyl-S-(2-hydroxypropyl)-L-cysteine (2HPMA) (OR = 2.85, 95% CI = 1.04, 7.81). Estimates were not significant with adjustment for opium use. Concentrations of many biomarkers were higher at the baseline for participants who subsequently developed lung cancer than among the matched controls. Odds of lung cancer were higher for several biomarkers including with adjustment for smoking exposure for some but not with adjustment for opium use.

Published
2021

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