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4. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, Piccinelli, Sara, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, D'Arminio Monforte, Antonella, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, and Gismondo, Maria Rita

Published
2024
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6. Evaluation of analytical performance of the STANDARD™ M10 MPX/OPX assay for the simultaneous DNA detection and clade attribution of Monkeypox virus.

Author

Mancon, Alessandro, Raccagni, Angelo Roberto, Gagliardi, Gloria, Moschese, Davide, Rizzo, Alberto, Giacomelli, Andrea, Cutrera, Miriam, Salari, Federica, Bracchitta, Fiorenza, Antinori, Spinello, Gori, Andrea, Rizzardini, Giuliano, Castagna, Antonella, Gismondo, Maria Rita, Nozza, Silvia, and Mileto, Davide

Published
2024
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8. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Piralla, A, Mileto, D, Rizzo, A, Ferrari, G, Giardina, F, Gaiarsa, S, Petazzoni, G, Bianchi, M, Salari, F, Bracchitta, F, Sammartino, J, Ferrari, A, Gagliardi, G, Mancon, A, Fenizia, C, Biasin, M, Rovida, F, Paolucci, S, Percivalle, E, Lombardi, A, Micheli, V, Nozza, S, Castagna, A, Moschese, D, Antinori, S, Gori, A, Bonfanti, P, Rossotti, R, Monforte, A, Attanasi, F, Tirani, M, Cereda, D, Baldanti, F, Gismondo, M, Cutrera, M, Cuomo, M, De Poli, F, Campanini, G, Pitrolo, A, Iskandar, E, Cassaniti, I, Bruno, R, Rizzardini, G, Puoti, M, Castelli, F, Corsico, L, Giacomelli, A, Pozza, G, Casalini, G, Raccagni, A, Trentacapilli, B, Bertoni, C, Bruzzesi, E, Candela, C, Tesoro, D, Mule, G, Bandera, A, Bianca Mariani, A, Maffeo, M, Vecchio, R, Piccinelli, S, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, Monforte, Antonella D'arminio, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, Gismondo, Maria Rita, Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, Piccinelli, Sara, Piralla, A, Mileto, D, Rizzo, A, Ferrari, G, Giardina, F, Gaiarsa, S, Petazzoni, G, Bianchi, M, Salari, F, Bracchitta, F, Sammartino, J, Ferrari, A, Gagliardi, G, Mancon, A, Fenizia, C, Biasin, M, Rovida, F, Paolucci, S, Percivalle, E, Lombardi, A, Micheli, V, Nozza, S, Castagna, A, Moschese, D, Antinori, S, Gori, A, Bonfanti, P, Rossotti, R, Monforte, A, Attanasi, F, Tirani, M, Cereda, D, Baldanti, F, Gismondo, M, Cutrera, M, Cuomo, M, De Poli, F, Campanini, G, Pitrolo, A, Iskandar, E, Cassaniti, I, Bruno, R, Rizzardini, G, Puoti, M, Castelli, F, Corsico, L, Giacomelli, A, Pozza, G, Casalini, G, Raccagni, A, Trentacapilli, B, Bertoni, C, Bruzzesi, E, Candela, C, Tesoro, D, Mule, G, Bandera, A, Bianca Mariani, A, Maffeo, M, Vecchio, R, Piccinelli, S, Piralla, Antonio, Mileto, Davide, Rizzo, Alberto, Ferrari, Guglielmo, Giardina, Federica, Gaiarsa, Stefano, Petazzoni, Greta, Bianchi, Micol, Salari, Federica, Bracchitta, Fiorenza, Sammartino, Josè Camilla, Ferrari, Alessandro, Gagliardi, Gloria, Mancon, Alessandro, Fenizia, Claudio, Biasin, Mara, Rovida, Francesca, Paolucci, Stefania, Percivalle, Elena, Lombardi, Alessandra, Micheli, Valeria, Nozza, Silvia, Castagna, Antonella, Moschese, Davide, Antinori, Spinello, Gori, Andrea, Bonfanti, Paolo, Rossotti, Roberto, Monforte, Antonella D'arminio, Attanasi, Federica, Tirani, Marcello, Cereda, Danilo, Baldanti, Fausto, Gismondo, Maria Rita, Cutrera, Miriam, Cuomo, Marianna, De Poli, Federica, Campanini, Giulia, Pitrolo, Antonino Maria Guglielmo, Iskandar, Elizabeth, Cassaniti, Irene, Bruno, Raffaele, Rizzardini, Giuliano, Puoti, Massimo, Castelli, Francesco, Corsico, Laura, Giacomelli, Andrea, Pozza, Giacomo, Casalini, Giacomo, Raccagni, Angelo, Trentacapilli, Bendetta, Bertoni, Costanza, Bruzzesi, Elena, Candela, Caterina, Tesoro, Daniele, Mule, Giovanni, Bandera, Alessandra, Bianca Mariani, Antonio Muscatello, Maffeo, Manuel, Vecchio, Riccardo, and Piccinelli, Sara

Abstract

Background: Mpox virus (MPXV) has recently spread outside of sub-Saharan Africa. This large multicentre study was conducted in Lombardy, the most densely populated Italian region accounting for more than 40% of Italian cases. The present study aims to: i) evaluate the presence and the shedding duration of MPXV DNA in different body compartments correlating the MPXV viability with the time to onset of symptoms; ii) provide evidence of MPXV persistence in different body compartment as a source of infection and iii) characterize the MPXV evolution by whole genome sequencing (WGS) during the outbreak occurred in Italy. Material and methods: The study included 353 patients with a laboratory-confirmed diagnosis of MPXV infection screened in several clinical specimens in the period May 24th - September 1st, 2022. Viral isolation was attempted from different biological matrices and complete genome sequencing was performed for 61 MPXV strains. Results: MPXV DNA detection was more frequent in the skin (94.4%) with the longest median time of viral clearance (16 days). The actively-replicating virus in cell culture was obtained for 123/377 (32.6%) samples with a significant higher viral quantity on isolation positive samples (20 vs 31, p < 0.001). The phylogenetic analysis highlighted the high genetic identity of the MPXV strains collected, both globally and within the Lombardy region. Conclusion: Skin lesion is gold standard material and the high viral load and the actively-replicating virus observed in genital sites confirms that sexual contact plays a key role in the viral transmission.

Published
2024

9. Evaluation of 16S-Based Metagenomic NGS as Diagnostic Tool in Different Types of Culture-Negative Infections.

Author

Rimoldi, Sara Giordana, Tamoni, Alessandro, Rizzo, Alberto, Longobardi, Concetta, Pagani, Cristina, Salari, Federica, Matinato, Caterina, Vismara, Chiara, Gagliardi, Gloria, Cutrera, Miriam, and Gismondo, Maria Rita

Subjects
NUCLEOTIDE sequencing, CUTIBACTERIUM acnes, STAPHYLOCOCCUS epidermidis, BACTERIAL cultures, CARDIAC surgery
Abstract

Bacterial infections pose significant global health challenges, often underestimated due to difficulties in accurate diagnosis, especially when culture-based diagnostics fail. This study assesses the effectiveness of 16S-based metagenomic next generation sequencing (NGS) for identifying pathogens in culture-negative clinical samples across various medical settings. Overall, 48% of samples were collected from orthopedics, 15% from neurosurgery, and 12% in cardiac surgery, among others. The detection rate of monomicrobial infections was 68.6%, and 5.7% for polymicrobial infections. In addition, NGS detected bacteria in all samples from the lungs, head and neck, and eye specimens. Cutibacterium acnes (11%, 12/105) was the most frequent microorganism, followed by Staphylococcus epidermidis (10.4%, 11/105), and Staphylococcus aureus (9.5%, 10/105). In conclusion, 16S-targeted metagenomic sequencing enhances pathogen detection capabilities, particularly in instances where traditional cultures fail. By the combination of NGS and bacterial cultures, microbiologists might provide a more accurate diagnosis, guiding more effective treatments and potentially reducing healthcare costs associated with empirical treatments. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Dynamics of viral DNA shedding and culture viral DNA positivity in different clinical samples collected during the 2022 mpox outbreak in Lombardy, Italy

Author

Piralla, Antonio, primary, Mileto, Davide, additional, Rizzo, Alberto, additional, Ferrari, Guglielmo, additional, Giardina, Federica, additional, Gaiarsa, Stefano, additional, Petazzoni, Greta, additional, Bianchi, Micol, additional, Salari, Federica, additional, Bracchitta, Fiorenza, additional, Sammartino, Josè Camilla, additional, Ferrari, Alessandro, additional, Gagliardi, Gloria, additional, Mancon, Alessandro, additional, Fenizia, Claudio, additional, Biasin, Mara, additional, Rovida, Francesca, additional, Paolucci, Stefania, additional, Percivalle, Elena, additional, Lombardi, Alessandra, additional, Micheli, Valeria, additional, Nozza, Silvia, additional, Castagna, Antonella, additional, Moschese, Davide, additional, Antinori, Spinello, additional, Gori, Andrea, additional, Bonfanti, Paolo, additional, Rossotti, Roberto, additional, Monforte, Antonella D'arminio, additional, Attanasi, Federica, additional, Tirani, Marcello, additional, Cereda, Danilo, additional, Baldanti, Fausto, additional, Gismondo, Maria Rita, additional, Cutrera, Miriam, additional, Cuomo, Marianna, additional, De Poli, Federica, additional, Campanini, Giulia, additional, Pitrolo, Antonino Maria Guglielmo, additional, Iskandar, Elizabeth, additional, Cassaniti, Irene, additional, Bruno, Raffaele, additional, Rizzardini, Giuliano, additional, Puoti, Massimo, additional, Castelli, Francesco, additional, Corsico, Laura, additional, Giacomelli, Andrea, additional, Pozza, Giacomo, additional, Casalini, Giacomo, additional, Raccagni, Angelo, additional, Trentacapilli, Bendetta, additional, Bertoni, Costanza, additional, Bruzzesi, Elena, additional, Candela, Caterina, additional, Tesoro, Daniele, additional, Mule, Giovanni, additional, Bandera, Alessandra, additional, Bianca Mariani, Antonio Muscatello, additional, Maffeo, Manuel, additional, Vecchio, Riccardo, additional, and Piccinelli, Sara, additional

Published
2024
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14. Natural language processing techniques for studying language in pathological ageing: A scoping review.

Author

Gagliardi, Gloria

Subjects
*PSYCHOLOGICAL aspects of aging, *MEDICAL databases, *COGNITION disorders, *BIOMARKERS, *SPEECH therapy, *DYSARTHRIA, *FRAIL elderly, *PHONOLOGICAL awareness, *NATURAL language processing, *SYSTEMATIC reviews, *LINGUISTICS, *CONFERENCES & conventions, *DEMENTIA, *LITERATURE reviews, *MEDLINE, *LANGUAGE disorders, *DISEASE complications
Abstract

Background: In the past few years there has been a growing interest in the employment of verbal productions as digital biomarkers, namely objective, quantifiable behavioural data that can be collected and measured by means of digital devices, allowing for a low‐cost pathology detection, classification and monitoring. Numerous research papers have been published on the automatic detection of subtle verbal alteration, starting from written texts, raw speech recordings and transcripts, and such linguistic analysis has been singled out as a cost‐effective method for diagnosing dementia and other medical conditions common among elderly patients (e.g., cognitive dysfunctions associated with metabolic disorders, dysarthria). Aims: To provide a critical appraisal and synthesis of evidence concerning the application of natural language processing (NLP) techniques for clinical purposes in the geriatric population. In particular, we discuss the state of the art on studying language in healthy and pathological ageing, focusing on the latest research efforts to build non‐intrusive language‐based tools for the early identification of cognitive frailty due to dementia. We also discuss some challenges and open problems raised by this approach. Methods & Procedures: We performed a scoping review to examine emerging evidence about this novel domain. Potentially relevant studies published up to November 2021 were identified from the databases of MEDLINE, Cochrane and Web of Science. We also browsed the proceedings of leading international conferences (e.g., ACL, COLING, Interspeech, LREC) from 2017 to 2021, and checked the reference lists of relevant studies and reviews. Main Contribution: The paper provides an introductory, but complete, overview of the application of NLP techniques for studying language disruption due to dementia. We also suggest that this technique can be fruitfully applied to other medical conditions (e.g., cognitive dysfunctions associated with dysarthria, cerebrovascular disease and mood disorders). Conclusions & Implications: Despite several critical points need to be addressed by the scientific community, a growing body of empirical evidence shows that NLP techniques can represent a promising tool for studying language changes in pathological aging, with a high potential to lead a significant shift in clinical practice. WHAT THIS PAPER ADDS: What is already known on this subject: Speech and languages abilities change due to non‐pathological neurocognitive ageing and neurodegenerative processes. These subtle verbal modifications can be measured through NLP techniques and used as biomarkers for screening/diagnostic purposes in the geriatric population (i.e., digital linguistic biomarkers—DLBs). What this paper adds to existing knowledge: The review shows that DLBs can represent a promising clinical tool, with a high potential to spark a major shift to dementia assessment in the elderly. Some challenges and open problems are also discussed. What are the potential or actual clinical implications of this work?: This methodological review represents a starting point for clinicians approaching the DLB research field for studying language in healthy and pathological ageing. It summarizes the state of the art and future research directions of this novel approach. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Immune Response and Transplacental Antibody Transfer in Pregnant Women after COVID-19 Vaccination

Author

Lubrano, Chiara, primary, Mancon, Alessandro, additional, Anelli, Gaia Maria, additional, Gagliardi, Gloria, additional, Corneo, Roberta, additional, Bianchi, Micol, additional, Coco, Chiara, additional, Dal Molin, Giulia, additional, Vignali, Michele, additional, Schirripa, Irene, additional, Di Simone, Nicoletta, additional, Pavone, Giulia, additional, Pellegrino, Antonio, additional, Gismondo, Maria Rita, additional, Savasi, Valeria Maria, additional, and Cetin, Irene, additional

Published
2023
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17. IPAN - Interdisciplinary Perspectives on Anorexia Nervosa: Book of Abstracts

Author

Gagliardi, Gloria, Vernillo, Paola, Gagliardi, Gloria, and Vernillo, Paola

Abstract

This book collects 17 contributions by scholars and experts interested in the study of anorexia nervosa (AN) and eating disorders (ED) in different research fields (among others, Linguistics, Psychology, and Neuropsychiatry). All the contributions will be presented at the upcoming IPAN (Interdisciplinary Perspectives on Anorexia Nervosa) conference, a one-day event that will be hosted in Bologna on May 26, 2023, by the Department of Classical Philology and Italian Study - University of Bologna (Italy), in collaboration with RaAM (Association for Researching and Applying Metaphors). The conference aims at fostering multidisciplinary exchange about research on AN and, more in general, on ED. With this volume we want to mash up ideas and research methods of experts, scholars, and students from different theoretical and experimental backgrounds, this way providing an environment for dialogue and integration.

Published
2023

18. CLUB Working Papers in Linguistics Volume 7

Author

Cervini, Cristiana, Gagliardi, Gloria, Cervini, Cristiana, and Gagliardi, Gloria

Abstract

Il volume raccoglie una selezione dei contributi presentati nel corso della settima edizione del CLUB - Circolo Linguistico dell'Università di Bologna durante l’anno accademico 2021/2022. I dieci saggi che compongono questa miscellanea sono (in ordine alfabetico) a firma di Laura Barbagli, Arianna Biagioni, Chiara Bonsignori, Cosimo Burgassi, Pietro Celo, Olivia Costantini, Gloria Gagliardi, Elisa Guadagnini, Edoardo Lombardi Vallauri, Ignacio Martínez Buffa, Viviana Masia, Simone Mattiola, Marco Mazzoleni, Emanuele Miola, Cecilia Meriggi, Flavio Pisciotta e Virginia Volterra. Tutti i contributi, disponibili in formato open access, sono stati sottoposti a un processo di revisione anonima da parte di due reviewer esperti.

Published
2023

21. Human Monkeypox Experience in a Tertiary Level Hospital in Milan, Italy, between May and October 2022: Epidemiological Features and Clinical Characteristics

Author

Candela, Caterina, primary, Raccagni, Angelo Roberto, additional, Bruzzesi, Elena, additional, Bertoni, Costanza, additional, Rizzo, Alberto, additional, Gagliardi, Gloria, additional, Canetti, Diana, additional, Gianotti, Nicola, additional, Mileto, Davide, additional, Gismondo, Maria Rita, additional, Castagna, Antonella, additional, and Nozza, Silvia, additional

Published
2023
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22. Oropouche fever diagnosed in Milan, Italy in returning travellers from Rio de Janeiro, March 2024, and Cuba, July 2024.

Author

Mancon, Alessandro, Gagliardi, Gloria, Giacomelli, Andrea, Vezzosi, Luigi, Gori, Andrea, Antinori, Spinello, Cereda, Danilo, Gismondo, Maria Rita, and Mileto, Davide

Subjects
*INFORMED consent (Medical law), *WEST Nile virus, *FATIGUE (Physiology), *SYMPTOMS, *JOINT pain, *PESTE des petits ruminants
Abstract

The article discusses the diagnosis of Oropouche fever in Milan, Italy, in travelers returning from Rio de Janeiro, Brazil, and Cuba. Oropouche fever is caused by Orthobunyavirus oropoucheense (OROV) and is mainly observed in the Amazon region. The study highlights the need for molecular diagnosis among travelers from Latin America with febrile illness and emphasizes the importance of differential diagnosis and surveillance to address the increasing spread of new arboviruses. [Extracted from the article]

Published
2024
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23. Linking acetylated α-Tubulin redistribution to α-Synuclein pathology in brain of Parkinson’s disease patients

Author

Mazzetti, Samanta, primary, Giampietro, Federica, additional, Isilgan, Huseyin Berkcan, additional, Calogero, Alessandra Maria, additional, Gagliardi, Gloria, additional, Rolando, Chiara, additional, Cantele, Francesca, additional, Ascagni, Miriam, additional, Bramerio, Manuela, additional, Giaccone, Giorgio, additional, Isaias, Ioannis Ugo, additional, Pezzoli, Gianni, additional, and Cappelletti, Graziella, additional

Published
2022
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24. Concomitant diagnosis of sexually transmitted infections and human monkeypox in patients attending a sexual health clinic in Milan, Italy

Author

Rizzo, Alberto, primary, Pozza, Giacomo, additional, Salari, Federica, additional, Giacomelli, Andrea, additional, Mileto, Davide, additional, Cossu, Maria Vittoria, additional, Mancon, Alessandro, additional, Gagliardi, Gloria, additional, Micol, Bianchi, additional, Micheli, Valeria, additional, Capetti, Amedeo, additional, Antinori, Spinello, additional, Gismondo, Maria Rita, additional, Olivieri, Pietro, additional, and Lombardi, Alessandra, additional

Published
2022
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25. Extraction and Classification of Acoustic Features from Italian Speaking Children with Autism Spectrum Disorders

Author

Beccaria Federica, Gagliardi Gloria, Dimitrios Kokkinakis, D. Kokkinakis, C. K. Themistocleous, K. Lundholm Fors, A. Tsanas, K. C. Fraser, and Beccaria Federica, Gagliardi Gloria, Dimitrios Kokkinakis

Subjects
Autism Spectrum Disorders, acoustic analysis, machine learning, openSMILE, eGeMAPS
Abstract

Autism Spectrum Disorders (ASD) are a group of complex developmental conditions whose effects and severity show high intraindividual variability. However, one of the main symptoms shared along the spectrum is social interaction impairments that can be explored through acoustic analysis of speech production. In this paper, we compare 14 Italian-speaking children with ASD and 14 typically developing peers. Accordingly, we extracted and selected the acoustic features related to prosody, quality of voice, loudness, and spectral distribution using the parameter set eGeMAPS provided by the openSMILE feature extraction toolkit. We implemented four supervised machine learning methods to evaluate the extraction performances. Our findings show that Decision Trees (DTs) and Support Vector Machines (SVMs) are the best-performing methods. The overall DT models reach a 100% recall on all the trials, meaning they correctly recognise autistic features. However, half of its models overfit, while SVMs are more consistent. One of the results of the work is the creation of a speech pipeline to extract Italian speech biomarkers typical of ASD by comparing our results with studies based on other languages. A better understanding of this topic can support clinicians in diagnosing the disorder.

Published
2022

26. The Automatic Extraction of Linguistic Biomarkers as a Viable Solution for the Early Diagnosis of Mental Disorders

Author

Gagliardi Gloria, Tamburini Fabio, Nicoletta Calzolari, Frédéric Béchet, Philippe Blache, Khalid Choukri, Christopher Cieri, Thierry Declerck, Sara Goggi, Hitoshi Isahara, Bente Maegaard, Joseph Mariani, Hélène Mazo, Jan Odijk, and Stelios Piperidis, Gagliardi Gloria, and Tamburini Fabio

Subjects
Mental Disorders, Automatic Speech and Language Analysis, Digital Linguistic Biomarkers
Abstract

Digital Linguistic Biomarkers extracted from spontaneous language productions proved to be very useful for the early detection of various mental disorders. This paper presents a computational pipeline for the automatic processing of oral and written texts: the tool enables the computation of a rich set of linguistic features at the acoustic, rhythmic, lexical, and morphosyntactic levels. Several applications of the instrument - for the detection of Mild Cognitive Impairments, Anorexia Nervosa, and Developmental Language Disorders - are also briefly discussed.

Published
2022

28. Decay rate of antiS1/S2 IgG serum levels after 6 months of BNT162b2 vaccination in a cohort of COVID-19-naive and COVID-19-experienced subjects

Author

Borgonovo, Fabio, primary, Stangalini, Carlo Alberto, additional, Tinelli, Carmine, additional, Mariani, Chiara, additional, Mileto, Davide, additional, Cossu, Maria Vittoria, additional, Abbati, Laura, additional, Bilardo, Lara, additional, Gagliardi, Gloria, additional, Cutrera, Miriam, additional, Pellicciotta, Martina, additional, Armiento, Luciana, additional, Dedivitiis, Gianfranco, additional, Capetti, Amedeo F., additional, and Rizzardini, Giuliano, additional

Published
2022
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29. Concomitant diagnosis of sexually transmitted infections and human monkeypox in patients attending a sexual health clinic in Milan, Italy.

Author

Rizzo, Alberto, Pozza, Giacomo, Salari, Federica, Giacomelli, Andrea, Mileto, Davide, Cossu, Maria Vittoria, Mancon, Alessandro, Gagliardi, Gloria, Micol, Bianchi, Micheli, Valeria, Capetti, Amedeo, Antinori, Spinello, Gismondo, Maria Rita, Olivieri, Pietro, and Lombardi, Alessandra

Subjects
SEXUALLY transmitted diseases, COMORBIDITY, MONKEYPOX, SEXUAL health, TRICHOMONAS vaginalis, TRICHOMONIASIS, GONORRHEA
Abstract

In 2022, many monkeypox (MPX) outbreaks have been documented in countries where MPX was not endemic. It spread all around the world, especially in European Union and United States. While MPX is classically considered to be transmitted through close contact with lesions, the hypothesis of sexual transmission has been proposed. This study considered a total of 49 patients suspected for MPX that were also tested for other sexually transmitted infections (STIs), including Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, and Trichomonas vaginalis. The data from coinfected patients suggested that MPXV and STIs might share the same route of inoculum, corroborating the hypothesis of possible sexual transmission for the emerging poxvirus. And like any other STI, MPX should be considered without stigmatization. [ABSTRACT FROM AUTHOR]

Published
2023
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30. La relazione gesto/prosodia e la sua variabilità: il parlato spontaneo di contro alla performance attorale. Selezione, comparazione e validazione della variazione diamesica e modale

Author

Cantalini Giorgina, Moneglia Massimo, Gagliardi Gloria, Proietti Morgana, Anna De Meo, Francesca Maria Dovetto, Cantalini Giorgina, Moneglia Massimo, Gagliardi Gloria, and Proietti Morgana

Subjects
struttura informativa, intonazione, gesto
Abstract

Il presente lavoro presenta alcuni risultati derivati dall'analisi comparativa sulla gestualità e la prosodia svolta su due campioni di parlato monologico, rispettivamente spontaneo e recitato, e contestualmente illustra gli aspetti metodologici relativi alla loro raccolta, annotazione e validazione.

Published
2020

31. An NLP pipeline as assisted transcription tool for speech therapists

Author

Gagliardi Gloria, Gregori Lorenzo, Ravelli Andrea Amelio, Dimitrios Kokkinakis, Kristina Lundholm Fors, Charalambos Themistocleous, Malin Antonsson, Marie Eckerström, and Gagliardi Gloria, Gregori Lorenzo, Ravelli Andrea Amelio

Subjects
Pathological Speech Processing, Developmental Language Disorder, PoS Tagging, Lemmatization, Pathological Speech Processing, Developmental Language Disorder, PoS Tagging, Lemmatization
Abstract

This work presents the design of a computer-assisted transcription system for speech-language therapists and an evaluation of its core-module: the NLP pipeline. This pipeline combines a tokenizer, a lemmatizer, a part-of-speech tagger and a spellchecker to perform a semi-automatic annotation of speech transcriptions. The implemented module has been evaluated on a corpus of spoken interaction of children with Developmental Language Disorder (DLD) with the caregiver. Results are promising in automatic error detection (F-measure of 0.547 against a Ground Truth of 0.616) but low in automatic error correction, and confirm the effectiveness within an assisted transcription tool.

Published
2020

32. SMAAV e DILLo. Nuovi strumenti per la valutazione e il trattamento clinico del linguaggio dall’incontro tra linguistica, logopedia e informatica

Author

Corsi Giulia, Gagliardi Gloria, Gregori Lorenzo, Dovetto Francesca Maria, and Corsi Giulia, Gagliardi Gloria, Gregori Lorenzo

Subjects
Linguistica clinica, strumenti per la valutazione logopedica, ICT per il linguaggio
Abstract

Il lavoro si prefigge lo scopo di mostrare l’importanza dell’integrazione di competenze neuropsicologiche e linguistiche, tramite l’illustrazione di due strumenti per la valutazione e il trattamento dei disturbi del linguaggio in età evolutiva, adulta e involutiva: SMAAV e DILLo. SMAAV – Semantic Memory Assessment on Action Verbs è una batteria psicometrica che sfrutta le proprietà linguistiche dei verbi di azione per indagare l’integrità del sistema semantico–lessicale. DILLo – Database Italiano del Lessico per Logopedisti è, invece, un’applicazione web orientata alla riabilitazione del linguaggio che consente di estrarre liste di parole filtrate secondo criteri linguistici pertinenti alle finalità cliniche. Entrambi gli strumenti sono caratterizzati dall’utilizzo di tecnologie ICT applicate all’ambito sanitario.

Published
2020

33. Proceedings of the Seventh Italian Conference on Computational Linguistics CLiC-it 2020

Author

Altuna, Begoña, Alzetta, Chiara, Anselma, Luca, Antinori, Alessandro, Aprosio, Alessio Palmero, Ardito, Luca, Argese, Chiara, Bacco, Luca, Baisa, Vít, Balaraman, Vevake, Barrón-Cedeño, Alberto, Basile, Pierpaolo, Basile, Valerio, Basili, Roberto, Bassignana, Elisa, Benvenuti, Nicola, Bernardi, Raffaella, Bertino, Enrico, Biasion, Davide, Biffi, Marco, Bolioli, Andrea, Bonadiman, Daniele, Bonora, Paolo, Bosca, Alessio, Bosco, Cristina, Brambilla, Silvia, Brunato, Dominique, Bucur, Ana-Maria, Cafagna, Michele, Caligiore, Gaia, Cappa, Claudia, Caputo, Annalina, Carlino, Carola, Caselli, Tommaso, Cassotti, Pierluigi, Castagnoli, Sara, Casula, Camilla, Cecchini, Flavio M., Celli, Fabio, Cervone, Alessandra, Chiusaroli, Francesca, Chung, Yi-Ling, Cignarella, Alessandra Teresa, Cimino, Andrea, Colla, Davide, Coltrinari, Riccardo, Colucci, Ilaria, Corino, Elisa, Croce, Danilo, Dell’Orletta, Felice, Delsanto, Matteo, de Gemmis, Marco, De Mattei, Lorenzo, de Varda, Andrea Gregor, Dinu, Liviu P., di Buono, Maria Pia, Di Gangi, Mattia Antonino, Di Lascio, Mirko, Ducret, Martina, Fabris, Alessandro, Falco, Mariacristina, Favalli, Andrea, Favaro, Manuel, Feldman, Anna, Fernández, Raquel, Fernicola, Francesco, Ferro, Marcello, Franzini, Greta, Gabrieli, Giuliano, Gagliardi, Gloria, Gaido, Marco, Gandolfi, Greta, Garcea, Federico, Gatt, Albert, Gemmis, Marco de, Giannone, Cristina, Giulivi, Sara, Gregori, Lorenzo, Gualdoni, Eleonora, Guerini, Marco, Hoste, Veronique, Iavarone, Benedetta, Jezek, Elisabetta, Karakanta, Alina, Kopp, Stefan, Kruse, Lauren, Lavelli, Alberto, Lenci, Alessandro, Liello, Luca Di, Lim, Alfred, Lops, Pasquale, Louvan, Samuel, Magnini, Bernardo, Mambrini, Francesco, Mana, Dario, Manna, Raffaele, Marino, Gian Manuel, Martinez, Carlos, Marzi, Claudia, Masini, Francesca, Mattei, Andrea, Mazzei, Alessandro, Menini, Stefano, Mensa, Enrico, Merone, Mario, Miaschi, Alessio, Micheli, M. Silvia, Montemagni, Simonetta, Monti, Johanna, Moretti, Giovanni, Morisio, Maurizio, Moschitti, Alessandro, Muffo, Matteo, Musto, Cataldo, Nadalini, Andrea, Negri, Matteo, Nissim, Malvina, Nolano, Gennaro, Nuovo, Elisa Di, Oliveri, Isabeau, Onnis, Luca, Origlia, Antonio, Osenova, Petya, O’Brien, Beth A., Palmero Aprosio, Alessio, Papa, Sirio, Pascucci, Antonio, Passarotti, Marco, Patti, Viviana, Paulon, Luca, Pellegrini, Matteo, Pelosi, Serena, Peng, Jing, Pezzelle, Sandro, Pierucci, Maria Laura, Pirinen, Tommi A., Pirrelli, Vito, Polignano, Marco, Radicioni, Daniele P., Ravelli, Andrea Amelio, Rescigno, Argentina Anna, Riccardi, Giuseppe, Rizzo, Giuseppe, Roberti, Pierluigi, Roccabruna, Gabriel, Rodella, Anna, Romagnoli, Raniero, Romani, Emma, Ruggiero, Gaetana, Sanguinetti, Manuela, Sarti, Gabriele, Semeraro, Giovanni, Silvello, Gianmaria, Simeoni, Rossana, Simi, Maria, Simoniello, Vincenzo, Simov, Kiril, Speranza, Giulia, Speranza, Manuela, Spillo, Giuseppe, Sprugnoli, Rachele, Strapparava, Carlo, Sucameli, Irene, Suozzi, Alice, Susto, Gian Antonio, Tamburini, Fabio, Taxitari, Loukia, Tekiroğlu, Serra Sinem, Testoni, Alberto, Tonelli, Sara, Tripodi, Rocco, Trosterud, Trond, Turchi, Marco, Uva, Antonio, Vanmassenhove, Eva, Varvara, Rossella, Vassallo, Marco, Venturi, Giulia, Vigorelli, Pietro, Vitale, Pierluigi, Way, Andy, Wiechetek, Linda, Yavuz, Mehmet Can, Zampedri, Federica, Zaninello, Andrea, Zanoli, Roberto, Zarino, Wanda Punzi, Zhang, Shibingfeng, Dell'Orletta, Felice, Monti, Johanna, and Tamburini, Fabio

Subjects
Twitter during Pandemic, Automatic Sarcasm Detection, Linguistic Ostracism in Social Networks, AriEmozione, COVID-19, Linguistics, LAN000000, Quantitative Linguistic Investigations, Fine-grained sentiment analysis, Online Hate Speech, Computational Linguistics, DistilBERT, Depression from Social Media, Distributional Semantics, Gender Bias, CBX, AEREST, E3C Project, Multilingual NLU, TrAVaSI
Abstract

On behalf of the Program Committee, a very warm welcome to the Seventh Italian Conference on Computational Linguistics (CLiC-it 2020). This edition of the conference is held in Bologna and organised by the University of Bologna. The CLiC-it conference series is an initiative of the Italian Association for Computational Linguistics (AILC) which, after six years of activity, has clearly established itself as the premier national forum for research and development in the fields of Computational Linguistics and Natural Language Processing, where leading researchers and practitioners from academia and industry meet to share their research results, experiences, and challenges.

Published
2021

34. Editorial: Digital Linguistic Biomarkers: Beyond Paper and Pencil Tests

Author

Gagliardi, Gloria, Kokkinakis, Dimitrios, and Duñabeitia, Jon Andoni

Subjects
linguistic-based diagnosis, computational linguistics, Editorial, machine learning, speech processing and recognition, Psychology, linguistic biomarkers, computer-aided diagnosis, natural language processing, clinical linguistics
Published
2021

35. Rapid lateral-flow immunochromatographic tests to assess anti N/S IgG seropositivity after BNT162b2 vaccine: A cross-sectional study

Author

Pezzati, Laura, primary, Giacomelli, Andrea, additional, Mileto, Davide, additional, Conti, Federico, additional, Gagliardi, Gloria, additional, Rizzo, Alberto, additional, Milazzo, Laura, additional, Schiuma, Marco, additional, Covizzi, Alice, additional, Siano, Matteo, additional, Bassoli, Cinzia, additional, Passerini, Matteo, additional, Piscaglia, Marco, additional, Torre, Alessandro, additional, Oreni, Letizia, additional, Rizzardini, Giuliano, additional, Galli, Massimo, additional, Ridolfo, Anna Lisa, additional, and Antinori, Spinello, additional

Published
2021
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36. One-year durability of anti-spike IgG to SARS-CoV-2: Preliminary data from the anticrown prospective observational study one year durability of COVID-19 anti-spike IgG

Author

Capetti, Amedeo F., primary, Borgonovo, Fabio, additional, Mileto, Davide, additional, Gagliardi, Gloria, additional, Mariani, Chiara, additional, Lupo, Angelica, additional, Dedivitiis, Gianfranco, additional, Meraviglia, Paola, additional, Pellicciotta, Martina, additional, Armiento, Luciana, additional, Cossu, Maria V., additional, and Rizzardini, Giuliano, additional

Published
2021
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40. Acquisizione di strutture sintattiche complesse e sviluppo della coesione nei bambini con disturbo del linguaggio in età prescolare: uno studio pilota

Author

Gagliardi, Gloria and Gloria Gagliardi

Subjects
coesione testuale, acquisizione della morfo-sintassi, connessità testuale, text coherence, narrative competence, Disturbo Primario del Linguaggio, Developmental Language Disorder, acquisition of morphosyntax, competenza narrativa, text connexity
Abstract

La maturazione della competenza narrativa costituisce una tappa essenziale nello sviluppo cognitivo del bambino: raccontare una storia richiede infatti l’integrazione di numerose abilità di tipo linguistico e metalingu istico, oltre a un forte coinvolgimento delle funzioni mnesiche ed esecut ive. Lo studio si propone di valutare la capacità di elaborazione di strutture sintattiche complesse e dei meccanismi di coesione testuale in bambini in età prescolare con Disturbo Primario del Linguaggio in contesto semi - spontaneo, elicitando le produzioni mediante tre prove di retelling di storie., Annali del Dipartimento di Studi Letterari, Linguistici e Comparati. Sezione linguistica, V. 9 (2020): ANNALI del Dipartimento di Studi Letterari, Linguistici e Comparati Sezione linguistica

Published
2020

41. The acquisition of the clitic ci among typically developing Italian preschoolers: preliminary data.

Author

Suozzi, Alice and Gagliardi, Gloria

Subjects
ITALIAN language, LANGUAGE disorders, SOCIOLINGUISTICS, BIOMARKERS, PRESCHOOL children, MORPHEMICS
Abstract

This paper explores the acquisitional patterns of the Italian ci morpheme and its potential role as a clinical marker for Developmental Language Disorder (DLD) in Italian-speaking children, taking into account its distributional, sociolinguistic, and typological properties. To this purpose, we (i) administered a test for the elicited production of clitic pronouns in Italian - which we will refer to as "T-PEC" in the following - to 126 school-aged Italian speakers and (ii) developed a novel test focused on the ci morpheme in order to investigate its production by five-year-old typically developing children. The results and their theoretical interpretations are of particular interest since they could shed light on the acquisition of the morpheme, thus helping understand both typical and atypical grammar development. Given the continuity of the two, it could also be applied to the diagnosis and rehabilitation of DLD, which remains a major challenge for child neuropsychiatrists, psychologists, and speech-language therapists. [ABSTRACT FROM AUTHOR]

Published
2022
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43. Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson’s Disease and Atypical Parkinsonisms

Author

Mazzetti, Samanta, primary, De Leonardis, Mara, additional, Gagliardi, Gloria, additional, Calogero, Alessandra Maria, additional, Basellini, Milo Jarno, additional, Madaschi, Laura, additional, Costa, Ilaria, additional, Cacciatore, Francesca, additional, Spinello, Sonia, additional, Bramerio, Manuela, additional, Cilia, Roberto, additional, Rolando, Chiara, additional, Giaccone, Giorgio, additional, Pezzoli, Gianni, additional, and Cappelletti, Graziella, additional

Published
2020
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44. Proceedings of the Fifth Italian Conference on Computational Linguistics CLiC-it 2018

Author

Abramova, Ekaterina, Adorni, Giovanni, Agrawal, Ruchit, Aina, Laura, Albanese, Teresa, Albanesi, Davide, Alzetta, Chiara, Amore, Matteo, Antonelli, Oronzo, Aprosio, Alessio Palmero, Balaraman, Vevake, Basile, Pierpaolo, Basile, Valerio, Basili, Roberto, Bassignana, Elisa, Bellandi, Andrea, Bentivogli, Luisa, Bernardi, Raffaella, Bertoldi, Nicola, Bondielli, Alessandro, Bos, Johan, Bosco, Cristina, Bottini, Roberto, Brunato, Dominique, Brunato⋄, Dominique, Büchler, Marco, Buono, Maria Pia di, Busso, Lucia, Cabrio, Elena, Caruso, Valeria, Caselli, Tommaso, Cecchini, Flavio, Celli, Fabio, Cervone, Alessandra, Chesi, Cristiano, Chingacham, Anupama, Chiriatti, Giulia, Cimino, Andrea, Cocciu•, Eleonora, Colla, Davide, Comandini, Gloria, Cordeiro, Silvio Ricardo, Crepaldi, Davide, Croce, Danilo, Curtoni, Paolo, Cutugno, Francesco, dell’Oglio, Pietro, Dell’Orletta, Felice, Dell’Orletta⋄, Felice, De Felice, Irene, De Martino, Maria, Dini, Luca, Di Iorio, Angelo, Di Nunzio, Giorgio Maria, Draetta, Lia, Ducceschi, Luca, Elia, Annibale, Falavigna, Daniele, Federico, Marcello, Feltracco, Anna, Fernández, Raquel, Ferro, Michele, Fieromonte, Martina, Franzini, Greta, Gagliardi, Gloria, Gala, Valentina Della, Gambi, Enrico, Ghezzi, Ilaria, Giovannetti, Emiliano, Gobbi, Jacopo, Gretter, Roberto, Guarasci, Raffaele, Guerini, Marco, Günther, Fritz, Gurevych, Iryna, Herzog, Leonardo, Jezek, Elisabetta, Koceva, Forsina, Lai, Mirko, Laudanna, Alessandro, Lenci, Alessandro, Lepri, Bruno, Liano, Annarita, Limpens, Freddy, Louvan, Samuel, Lyding, Verena, Magnini, Bernardo, Magnolini, Simone, Mairano, Paolo, Mambrini, Francesco, Mana, Dario, Mancuso, Azzurra, Marchi, Simone, Marelli, Marco, Marini, Costanza, Mazzei, Alessandro, McGregor, Stephen, Melnikova, Elena, Menini, Stefano, Mensa, Enrico, Merenda, Flavio, Mollo, Eleonora, Montemagni, Simonetta, Montemagni⋄, Simonetta, Monti, Johanna, Moretti, Giovanni, Moritz, Maria, Nadalini, Andrea, Negri, Matteo, Nicolas, Lionel, Nissim, Malvina, Novielli, Nicole, Okinina, Nadezda, Pannitto, Ludovica, Paperno, Denis, Passalacqua, Samuele, Passaro, Lucia C., Passarotti, Marco, Patti, Viviana, Pecchioli, Alessandra, Pellegrini, Matteo, Petrolito, Ruggero, Pettenati, Maria Chiara, Piantanida, Giovanni, Poggi, Isabella, Porporato, Aureliano, Quinci, Vito, Radicioni, Daniele P., Ramisch, Carlos, Rapp, Amon, Riccardi, Giuseppe, Rossini, Daniele, Rotondi, Agata, Ruffolo, Paolo, Russo, Irene, Sagri, Maria Teresa, Sangati, Federico, Sanguinetti, Manuela, Savary, Agata, Savy, Renata, Simeoni, Rossana, Simi, Maria, Sorgente, Antonio, Speranza, Manuela, Sprugnoli, Rachele, Stede, Manfred, Stepanov, Evgeny A., Stingo, Michele, Tamburini, Fabio, Tebbifakhr, Amirhossein, Tonelli, Sara, Torre, Ilaria, Tortoreto, Giuliano, Totis, Pietro, Trotta, Daniela, Turchi, Marco, Valeriani, Martina, Venturi, Giulia, Venturi⋄, Giulia, Vezzani, Federica, Villata, Serena, Vincze, Veronika, Zaghi, Claudia, Zovato, Enrico, Cabrio, Elena, Mazzei, Alessandro, and Tamburini, Fabio

Subjects
elaborazione del linguaggio naturale, Computational Linguistics, History & Philosophy Of Science, analisi semantica, CBX, Gurevych (Iryna), Bos (Johan), LAN000000, linguistica computazionale, Natural Language Processing, semantic parsing
Abstract

On behalf of the Program Committee, a very warm welcome to the Fifth Italian Conference on Computational Linguistics (CLiC-­‐it 2018). This edition of the conference is held in Torino. The conference is locally organised by the University of Torino and hosted into its prestigious main lecture hall “Cavallerizza Reale”. The CLiC-­‐it conference series is an initiative of the Italian Association for Computational Linguistics (AILC) which, after five years of activity, has clearly established itself as the premier national forum for research and development in the fields of Computational Linguistics and Natural Language Processing, where leading researchers and practitioners from academia and industry meet to share their research results, experiences, and challenges.

Published
2019

48. Linguistic markers during spontaneous speech for detecting Mild Cognitive Impairment

Author

Beltrami, Daniela, Gagliardi, Gloria, Favretti, Rema Rossini, Calzà, Laura, Tamburini, Fabio, Ghidoni, Enrico, Beltrami, Daniela, Gagliardi, Gloria, Favretti, Rema Rossini, Calzà, Laura, Tamburini, Fabio, and Ghidoni, Enrico

Subjects
Mild Cognitive Impairment, Dementia, MCI, linguistic markers, Dementia, MCI, Mild Cognitive Impairment, linguistic markers
Published
2017

49. T-PEC: a novel test for the elicited production of clitic pronouns in Italian. Preliminary data.

Author

Crocetti, Perla, Fancelli, Stefano, Colpizzi, Ilaria, Suozzi, Alice, Crocetti, Emanuele, Borgogni, Elisa, and Gagliardi, Gloria

Subjects
LANGUAGE disorder diagnosis, AFFINITY groups, STATISTICS, LINGUISTICS, FISHER exact test, PSYCHOMETRICS, DESCRIPTIVE statistics, STATISTICAL correlation, RECEIVER operating characteristic curves, DATA analysis, LANGUAGE disorders in children, INTELLIGENCE tests
Abstract

The study presented in this article aims at investigating the clinical usefulness of a novel test, called T-PEC, for the diagnosis of Developmental Language Disorder in Italian preschool children. The instrument exploits the production of clitic pronouns, in particular third person direct object clitics (3PDO-CL), as a clinical marker for the disorder. Psychometric properties and normative data were computed on a sample of 70 children ranging in age from 4.6 to 5.8 years: 22 children diagnosed as language-impaired by expert clinicians according to international guidelines, and 48 typically developing peers. The statistical analysis of the collected data revealed good internal consistency (Cronbach's α = 0.86) and confirmed the effectiveness of the T-PEC test in distinguishing typically developing and DLD children, especially when the latter showed morphosyntactic deficits (AUC = 79.9%). Its high accuracy, combined with the rapidity and easiness of its administration, makes the T-PEC test suitable for use in clinical settings. [ABSTRACT FROM AUTHOR]

Published
2021
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