1. [Dexmedetomidine use for postoperative adrenergic analgesia and sedation in abdominal surgery].
- Author
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Gur'ianov VA, Nosenko MM, Gadzhibekov NCh, Ialich AIu, Aliautdin RN, and Tolmachev GN
- Subjects
- Analgesics, Non-Narcotic administration & dosage, Analgesics, Non-Narcotic adverse effects, Conscious Sedation methods, Dexmedetomidine administration & dosage, Dexmedetomidine adverse effects, Hemodynamics drug effects, Humans, Hypnotics and Sedatives administration & dosage, Hypnotics and Sedatives adverse effects, Pain, Postoperative metabolism, Parasympathetic Nervous System drug effects, Promedol administration & dosage, Promedol adverse effects, Promedol therapeutic use, Treatment Outcome, Abdomen surgery, Analgesics, Non-Narcotic therapeutic use, Dexmedetomidine therapeutic use, Hypnotics and Sedatives therapeutic use, Pain, Postoperative prevention & control, Receptors, Adrenergic, alpha-2 metabolism
- Abstract
Comparative study of postoperative analgesia and sedation with trimeperidine and dexmedetomidine and their effects on haemodynamics and vegetative nervous system was performed. Assessment of analgesia and sedation during vagotonia (first part of the study) and hypokinetic type of haemodynamics (second part of the study) was carried out with visual analogue scale (VAS) and Richmond scale. Results of the study showed that dexmedetomidine is more effective and safer than trimeperidine for analgesia and sedation in patients with spontaneous breathing after abdominal surgery. Dexmedetomidine use allows keeping optimal type of haemodynamics and vegetative nervous system parameters on first day of postoperative period.
- Published
- 2013