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2. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency

3. Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome

8. Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

10. List Of Contributors

13. A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus.

15. Whole Chromosome Instability induces senescence and promotes SASP.

17. 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine

18. Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

20. Clonal haematopoiesis across the age spectrum of vasculitis patients with Takayasu’s arteritis, ANCA-associated vasculitis and giant cell arteritis

24. Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation

25. Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy

33. List of Contributors

36. Biallelic hypomorphic mutations in a linear deubiquitinase define otulipenia, an early-onset autoinflammatory disease

37. Biallelic human SHARPINloss of function induces autoinflammation and immunodeficiency

42. Human LUBAC deficiency leads to autoinflammation and immunodeficiency by dysregulation in TNF-mediated cell death

43. The JAK-STAT pathway at 30: Much learned, much more to do

44. Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study

47. 10 - Cytokines

49. Improvement in Disease Activity in Refractory Juvenile Dermatomyositis Following Abatacept Therapy.

50. Tailoring cells for clinical needs: Meeting report from the Advanced Therapy in Healthcare symposium (October 28–29 2017, Doha, Qatar)

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