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34. TrialDB: A Web-based Clinical Study Data Management System AMIA 2003 Open Source Expo

Author

Brandt, CA, Deshpande, AM, Lu, C, Ananth, G, Sun, K, Gadagkar, R, Morse, R, Rodriguez, C., Miller, PL, and Nadkarni, PM

Subjects
Clinical Trials as Topic, Internet, Database Management Systems, Humans, Article
Abstract

Clinical Study Data Management Systems (CSDMSs) are a class of software that support centralized management of data generated during the conduct of clinical studies. Commercial CSDMSs include Oracle Clinical, ClinTrial and MetaTrial. Such systems, which are typically deployed at an institutional or organizational level, must accommodate diverse types of data from different clinical domains that is generated by different groups of clinical investigators. Large-scale CSDMSs typically employ a high-end database engine that is usually accessed over an intranet or the Internet using Web-based technologies. CSDMSs in institution-wide use for a variety of clinical domains are best served by entity-attribute-value (EAV) modeling for the clinical data: all the commercial CSDMSs that we are aware of use EAV design. However, de novo development of EAV databases for data management is a challenging task. A large body of generic metadata-driven code must be developed before a basic EAV application can be written. Clearly, the availability of pre-existing software with the requisite functionality would be very valuable. We will discuss the benefits of such software being in open-source form.

Published
2003

36. University-Education In Science

Author

Bhide, VG, Chandrasemar, J, Chandrashekaran, MK, Gupta, SD, Deb, BM, Gadagkar, R, Mukunda, N, Sitaram, A, Srinivas, V, Srinivasan, R, and Vidyasagar, M

Subjects
Centre for Ecological Sciences, Organic Chemistry
Published
1995

49. Natural history and behaviour of the primitively eusocial wasp Ropalidia marginata (Hymenoptera: Vespidae): a comparison of the two sexes.

Author

Sen, R. and Gadagkar, R.

Subjects
*NATURAL history, *ROPALIDIA marginata, *WASPS, *VESPIDAE, *HYMENOPTERA, *COMPARATIVE studies
Abstract

We report the natural history and behaviour of the primitively eusocial wasp Ropalidia marginata with a special reference to the males. We found that just as nests of this species are found throughout the year, so are the males. Females spend all their life in their nests but males stay in their natal nests only for 1-12 days and leave to lead a nomadic life. Males maintained in the laboratory can live for up to 140 days. Like all eusocial hymenopteran males, R. marginata males also do not perform any colony maintenance activities. We found that males did not forage or feed larvae. Compared with females, males showed fewer dominance and subordinate behaviours and being solicited behaviour and more feeding self and soliciting behaviours. By comparing males with young females, we found similar differences, except that the males showed similar rates of feeding self and higher rates of subordinate behaviour. [ABSTRACT FROM AUTHOR]

Published
2010
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