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The scraper conveyor chain transmission system is prone to frequent faults due to its complex load bearing capacity. However, traditional fault diagnosis requires a large amount of prior knowledge and subjective intervention, which requires high technical personnel. In order to achieve the autonomy, accuracy, and efficiency of fault warning for the scraper conveyor chain transmission system, a fault warning method for the scraper conveyor chain transmission system based on LSTM-Adam is proposed using the powerful data mining capability of deep learning. Firstly, a monitoring system for the working conditions of the scraper conveyor is built based on configuration technology. The system collects real-time operating data of the scraper conveyor, such as the torque and speed of the output shaft of the reducer, the pressure of the middle groove plate, the vibration acceleration in the vertical direction of the scraper, and the strain in the running direction of the scraper chain. The data is cleaned and normalized in min-max to provide data support for fault warning. Secondly, a prediction model is built based on LSTM and trained and optimized using the Adam optimization algorithm to obtain the optimal LSTM Adam prediction model. Finally, the real-time operating data of the scraper conveyor is imported into the LSTM-Adam prediction model to obtain the predicted values of the scraper conveyor operating parameters. The sliding weighted average method is used to calculate the residual between the predicted value and the true value. The maximum residual of the same type of data under normal operating conditions is used as the warning threshold. When the residual exceeds the warning threshold, an early warning is given. The experimental results show that the LSTM-Adam prediction model can accurately predict the trend of strain data of the scraper chain and provide accurate warnings for stuck chain and broken chain faults.

Photodynamic therapy (PDT) is a therapeutic modality that depends on the interaction of light, photosensitizers, and oxygen. The photon absorption and energy transfer process can lead to the Type II photochemical reaction of the photosensitizer and the production of singlet oxygen (1O2), which strongly oxidizes and reacts with biomolecules, ultimately causing oxidative damage to the target cells. Therefore, 1O2 is regarded as the key photocytotoxic species accountable for the initial photodynamic reactions for Type II photosensitizers. This article will provide a comprehensive review of 1O2 properties, 1O2 production, and 1O2 detection in the PDT process. The available 1O2 data of regulatory-approved photosensitizing drugs will also be discussed. [ABSTRACT FROM AUTHOR]