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This study examined the association between the energy-adjusted Dietary Inflammatory Index (E-DII)-based dietary inflammatory potential and depressive symptoms (DepS) among patients with breast cancer and explores whether systemic inflammation mediates this association. We assessed dietary intake and DepS in 220 breast cancer patients by three 24 h dietary recalls and the Center for Epidemiological Studies Depression Scale (CES-D), respectively, and determined plasma levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin (IL)-1β, IL-4, and IL-6 in 123 blood samples. We found that each one-point increase of E-DII was related to a 53% elevated risk of DepS. Patients with the most pro-inflammatory diets had a 5.13 times higher risk of DepS than those with the most anti-inflammatory diets. Among the E-DII components, vitamin B2, zinc, and iron were inversely associated with DepS risk. Furthermore, E-DII scores were positively associated with CRP and TNF-α. Higher levels of TNF-α and IL-6 were associated with higher DepS risk. A significant mediating effect of TNF-α was revealed between E-DII and DepS. Our findings suggest that a pro-inflammatory diet is positively associated with breast cancer-related DepS, which may be mediated by TNF-α. [ABSTRACT FROM AUTHOR]

Objective: This study assesses the impact of personalized health education on elderly patients with chronic diseases in a general practice setting. The rationale behind the incorporation of personalized health education stems from the growing recognition of the need for patient-centered care approaches, particularly in geriatric populations, where such interventions could lead to improved health outcomes. Our study aims to evaluate the effects of personalized health education on elderly patients with chronic diseases in a general practice context. The initiation of this study is grounded in the increasing acknowledgment of patient-centered care's significance, especially in geriatric demographics. We hypothesize that personalized health education interventions could significantly enhance health outcomes in this patient group., Methods: We conducted a randomized controlled trial involving 126 elderly patients with chronic diseases, assigning them equally to receive either standard care or standard care supplemented with personalized health education. The effectiveness of this education was measured through outcomes related to cognition, self-care, health literacy, psychological and physical health, quality of life, and prognosis. In our study, we executed a randomized controlled trial encompassing 126 elderly patients diagnosed with a range of chronic diseases. These participants were evenly divided into two groups: one receiving standard care and the other receiving standard care enhanced with personalized health education. The study spanned over a specified period, during which the impact of the personalized health education was meticulously evaluated. To comprehensively measure the effectiveness of the personalized health education, we employed a variety of tools and scales. These instruments were specifically chosen to assess changes in cognition, self-care abilities, health literacy, and psychological and physical health. Additionally, we evaluated the quality of life and prognosis of these patients, aiming to capture the holistic impact of the intervention. This approach ensured a thorough and nuanced understanding of how personalized health education influences the health outcomes of elderly patients with chronic diseases., Results: The intervention group demonstrated significant improvements across all measured outcomes compared to the control group, highlighting the efficacy of personalized health education in enhancing comprehensive health parameters in geriatric patients with chronic conditions. In our study, the intervention group, which received personalized health education, exhibited notable improvements in several key areas compared to the control group. Specifically, there was a marked enhancement in cognition and health literacy, with patients showing improved understanding and management of their conditions. Additionally, significant gains were observed in the quality of life, indicating that the tailored health education effectively addressed the holistic needs of geriatric patients with chronic diseases. These specific findings underscore the substantial impact of personalized health education in improving critical health outcomes in this patient population., Conclusion: Personalized health education in geriatric chronic disease management significantly betters disease comprehension, health literacy, self-care, psychological well-being, and physical health while also lowering the risk of adverse events. This study underscores the value of patient-centered educational strategies in chronic disease care for the elderly.Our study conclusively demonstrates that personalized health education plays a pivotal role in managing chronic diseases among the elderly. It significantly improves disease comprehension, health literacy, self-care capabilities, psychological well-being, and physical health. Furthermore, it contributes to a reduced risk of adverse health events. These findings emphasize the critical importance of integrating patient-centered educational strategies into general practice care for the elderly. By doing so, we can enhance their overall well-being and quality of life, making personalized health education an essential component in the holistic care of elderly patients with chronic conditions. This approach not only aligns with the principles of modern geriatric care but also sets a benchmark for the future of chronic disease management in older populations.

Objective: The purpose of this study was to investigate the therapeutic effects of improved emergency nursing procedures and human-oriented nursing care to patients in the acute phase of myocardial infarction.  This study is important because it aims to demonstrate the potential benefits of these nursing interventions in reducing negative feelings in patients with acute myocardial infarction and improving the success rate of first aid., Methods: A total of 180 inpatients with acute myocardial infarction hospitalized from January 2020 to December 2020 were selected as the research object and randomized into either study group or control group, with 90 cases in each. The study group received combined nursing care that included improved emergency nursing procedures and human-oriented nursing care, while the control group received conventional nursing care. The specific interventions in the study group included rapid response training, on-route care, hospital arrival protocol, human-oriented care training, psychological support measures, and a pain management protocol. The study evaluated SAS scores, mental state score, platelet index, first aid effect, thrombolysis and nursing satisfaction in comparison of the two groups., Results: Before receiving nursing care, there were no significant differences in the SAS scores between the study group and the control group (53.92±8.22 vs 54.03±8.56) (t = .09, P = .930, nonsignificant). However, after receiving care, patients in the study group had significantly lower SAS scores compared to the control group (9.21±2.67 vs 17.93±1.86) (t = 25.42, P < .001, statistically significant). Patients in the study group exhibited lower psychological scores compared to the control group in terms of depression, fear and paranoia (0.47±0.13 vs 0.76±0.12, 0.27±0.06 vs 0.46.±0.12, 0.67±0.29 vs 0.86±0.25) (t=15.55, 13.43, 4.71, all P < .001, statistically significant). Patients in the study group presented MPV levels as (12.41±1.31) and PDV level (14.26±1.23) while those had MPV level (10.02±1.21) and PDV level (18.68±1.83) in the control group (t=12.71, 19.01, both P < .001). The study group outperformed the control group in terms of first aid effects (P < .05, statistically significant). Thrombolysis was more effective in the study group compared to the control group (P < .05, statistically significant). Patients in the study group reported higher levels of satisfaction with the nursing service compared to those in the control group (P < .05, statistically significant)., Conclusion: The improved emergency nursing procedure and human-oriented nursing care can significantly reduce the hard feelings of patients with acute myocardial infarction, improve the success rate of first aid, and is worthy of extensive application and promotion. Healthcare providers and hospitals can benefit from adopting these nursing approaches to reduce negative feelings, improve first aid outcomes, and ultimately enhance patient satisfaction and treatment effectiveness.

Objective: This study explored the effects of social support, illness perception, coping style, and vision-related quality of life (VRQOL) in older patients with dry eye disease (DED) using a chain mediation model., Methods: A total of 407 patients with DED from a tertiary hospital in Wuxi, Jiangsu Province, China, between June and December 2023 were selected as participants. A demographic questionnaire, the Social Support Rating Scale, the Brief Illness Perception Questionnaire, the Medical Coping Modes Questionnaire, and the National Eye Institute Visual Functioning questionnaire-25 were all given to them to complete. IBM SPSS (version 27.0) was used for data analysis, and Model 6 of the PROCESS Macro was used to test the predicted chain mediation model., Results: The positive association between social support and VRQOL demonstrated the mediation role of illness perception and coping style. Social support affected VRQOL via three pathways: illness perception (effect = 0.190), confrontational coping style (effect = 0.103), and a combination of illness perception and confrontational coping style (effect = 0.067), accounted for 23.60%, 12.80%, and 8.32% of the total effect, respectively., Conclusion: Social support in older patients with DED can significantly and positively predict the VRQOL. In addition to the independent mediating effect of illness perception and confrontational coping style, a chain-mediating effect exists between social support and VRQOL. The study serves as a valuable strategy for healthcare professionals to prevent and intervene in VRQOL for older patients with DED in the future., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Pan, Pan, Gu and Wang.)