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Your search keyword '"GRZĄDZIEL, Aleksandra"' showing total 33 results
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33 results on '"GRZĄDZIEL, Aleksandra"'

1. Stereotactic management of arrhythmia - radiosurgery in treatment of ventricular tachycardia (SMART-VT). Results of a prospective safety trial

Author

Miszczyk, Marcin, Sajdok, Mateusz, Bednarek, Jacek, Latusek, Tomasz, Wojakowski, Wojciech, Tomasik, Bartłomiej, Wita, Krystian, Jadczyk, Tomasz, Kurzelowski, Radosław, Drzewiecka, Anna, Cybulska, Magdalena, Gardas, Rafał, Jarosiński, Grzegorz, Dolla, Łukasz, Grządziel, Aleksandra, Zub, Kamil, Bekman, Adam, Kaminiów, Konrad, Kozub, Anna, Gołba, Krzysztof S., and Blamek, Sławomir

Published
2023
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4. Optimal values of the Electron Monte Carlo dose engine parameters

Author

Wendykier, Jacek, primary, Wojtyna, Ewa, additional, Bekman, Barbara, additional, Bekman, Adam, additional, Woźniak, Bożena, additional, Niewiadomska, Beata, additional, Prażmowska, Joanna, additional, Wendykier, Piotr, additional, Bieniasiewicz, Marcin, additional, and Grządziel, Aleksandra, additional

Published
2023
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11. Stereotactic Radiotherapy in Combination with Immunotherapy in Treatment of Advanced Recurrent Squamous Cell Carcinoma of the Larynx.

Author

Polanowski, Paweł, Nasiek, Aleksandra, Grządziel, Aleksandra, Pietruszka, Agnieszka, Składowski, Krzysztof, and Polanowska, Katarzyna

Subjects
STEREOTACTIC radiotherapy, SQUAMOUS cell carcinoma, LARYNGECTOMY, IMMUNOTHERAPY, LARYNX, CHEMORADIOTHERAPY, NIVOLUMAB
Abstract

Squamous cell carcinoma (SCC) of the larynx in advanced stages is a challenging malignancy to treat with a high recurrence and death rate. An individualized approach to treatment is crucial in such patients. We present a 58-year-old male patient with SCC of the larynx in the T3N0M0 stage who was treated with concurrent radiochemotherapy. A total of 17 months after the radical treatment, the patient underwent a laryngectomy due to recurrence. A total of 11 months after the operation, local failure was diagnosed. In the next order, the patient received six cycles of palliative chemotherapy according to cisplatin 100 mg/m2 and 5-fluorouracil 1000 mg/m2. After three months, due to progression, Nivolumab-based immunotherapy was administered, ensuring disease stabilization. After the 56th cycle of Nivolumab, another progression was documented. The addition of stereotactic radiotherapy (18 Gy in three fractions) to immunotherapy led to significant regression of the disease and enabled the continuation of Nivolumab to the 70th cycle. The presented case demonstrates the usefulness of the combination of stereotactic radiotherapy with immunotherapy in prolonging the local control. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Escalating a Biological Dose of Radiation in the Target Volume Applying Stereotactic Radiosurgery in Patients with Head and Neck Region Tumours

Author

Polanowski, Paweł, primary, Składowski, Krzysztof, additional, Księżniak-Baran, Dorota, additional, Grządziel, Aleksandra, additional, Amrogowicz, Natalia, additional, Mrochem-Kwarciak, Jolanta, additional, Pietruszka, Agnieszka, additional, Kentnowski, Marek, additional, and Polanowska, Katarzyna, additional

Published
2022
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14. Influence of optional measurement parameters in the Eclipse treatment planning system on the quality of the dosimetric model of the biomedical accelerator using the Acuros XB algorithm

Author

Gądek, Adam, primary, Wendykier, Jacek, additional, Grządziel, Aleksandra, additional, Bekman, Barbara, additional, Smolińska, Barbara, additional, Bekman, Adam, additional, Niewiadomska, Beata, additional, Prażmowska, Joanna, additional, Woźniak, Bożena, additional, and Ślosarek, Krzysztof, additional

Published
2022
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21. Stereotactic management of arrhythmia – radiosurgery in treatment of ventricular tachycardia (SMART-VT) – clinical trial protocol and study rationale

Author

Miszczyk, Marcin, primary, Jadczyk, Tomasz, additional, Tomasik, Bartłomiej, additional, Latusek, Tomasz, additional, Bednarek, Jacek, additional, Kurzelowski, Radosław, additional, Gołba, Krzysztof, additional, Wojakowski, Wojciech, additional, Wita, Krystian, additional, Dolla, Łukasz, additional, Grządziel, Aleksandra, additional, and Blamek, Sławomir, additional

Published
2021
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24. EPID – a useful interfraction QC tool

Author

Klimas, Aleksandra, primary, Grządziel, Aleksandra, additional, Plaza, Dominika, additional, Bekman, Barbara, additional, Woźniak, Bożena, additional, Dolla, Łukasz, additional, Osewski, Wojciech, additional, Paściak, Paweł, additional, Wendykier, Jacek, additional, and Ślosarek, Krzysztof, additional

Published
2019
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25. Portal dosimetry in radiotherapy repeatability evaluation.

Author

Ślosarek, Krzysztof, Plaza, Dominika, Nas, Aleksandra, Reudelsdorf, Marta, Wendykier, Jacek, Bekman, Barbara, and Grządziel, Aleksandra

Subjects
FISHER exact test, RADIATION dosimetry, STATISTICAL reliability, STEREOTAXIC techniques, RADIOTHERAPY, STEREOTACTIC radiotherapy
Abstract

The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking methods. This work aims to present the possibility of using portal dosimetry in the assessment of radiotherapy repeatability. The analysis was conducted on 74 cases treated with dynamic techniques. Transit dosimetry was made for each collision‐free radiation beam. It allowed the comparison of summary fluence maps, obtained for fractions with the corresponding summary maps from all other treatment fractions. For evaluation of the compatibility in the fluence map pairs (6798), the gamma coefficient was calculated. The results were considered in four groups, depending on the used radiotherapy technique: stereotactic fractionated radiotherapy, breath‐hold, free‐breathing, and conventionally fractionated other cases. The chi2 or Fisher's exact test was made depending on the size of the analyzed set and also Mann–Whitney U‐test was used to compare treatment repeatability of different techniques. The aim was to test whether the null hypothesis of error‐free therapy was met. The patient is treated repeatedly if the P‐value in all the fluence maps sets is higher than the level of 0.01. The best compatibility between treatment fractions was obtained for the stereotactic technique. The technique with breath‐holding gave the lowest percentage of compliance of the analyzed fluence pairs. The results indicate that the repeatability of the treatment is associated with the radiotherapy technique. Treated volume location is also an essential factor found in the evaluation of treatment accuracy. The EPID device is a useful tool in assessing the repeatability of radiotherapy. The proposed method of fluence maps comparison also allows us to assess in which therapeutic session the patient was treated differently from the other fractions. [ABSTRACT FROM AUTHOR]

Published
2021
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