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2. Habitual Hyperthermia: An Interpretive Paradigm of the 20th Century? Not Really

Author

Ginier-Gillet M and Esparcieux A

Subjects
habitual hyperthermia, low-grade fever, patient-centered care, primary health care, pyrexia of unknown origin, undifferentiated febrile illness, Medicine (General), R5-920
Abstract

Mathieu Ginier-Gillet,1 Aurelie Esparcieux2 1Grenoble Faculty of Medicine, Grenoble Alpes University, La Tronche, France; 2Department of Internal Medicine and Infectious Diseases, Clinique de l’Infirmerie Protestante de Lyon, Caluire-et-Cuire, FranceCorrespondence: Mathieu Ginier-Gillet 55 Rue Ney, Lyon, 69006, FranceTel +33680854615Email dr.mathieu.giniergillet@gmail.comAbstract: Prolonged and unexplained fevers in young adults are uncommon, especially when access to diagnostic tests is simplified. Therefore, the definition of unexplained fever depends on the volume of tests performed. However, low-grade fever has not been a priority in research. Management of low-grade fever [eg, an oral temperature of ≥ 37.8°C (100°F) and < 38.3°C (101°F) at any time of the day] is not codified. The presented case of a 37-year-old nurse with an intermittent fever for three months, with no clear diagnostic evidence and no elevated markers of inflammation, illustrates “habitual hyperthermia” (HH)—retained after ordering tests sequentially in town and at the hospital. HH was made known by Prof. H.A. Reimann (1897– 1986) an American virologist, although the diagnostic criteria are fallible. The article reviews the criteria and then discusses how to select diagnostic tests in family practice for prolonged fever in young adults without clinical signs of orientation. Given the polymorphism of febrile illnesses, the principle of parsimony must be transgressed, and in the event of an early suspicion of HH, surveillance is a rule to be further amended.Keywords: habitual hyperthermia, low-grade fever, patient-centered care, primary health care, pyrexia of unknown origin, undifferentiated febrile illness

Published
2021

8. Safety and immunogenicity of the PRAME cancer immunotherapeutic in metastatic melanoma: results of a phase I dose escalation study

Author

Gutzmer, R., Rivoltini, L., Levchenko, E., Testori, A., Utikal, J., Ascierto, P.A., Demidov, L., Grob, J.J., Ridolfi, R., Schadendorf, D., Queirolo, P., Santoro, A., Loquai, C., Dreno, B., Hauschild, A., Schultz, E., Lesimple, T.P., Vanhoutte, N., Salaun, B., Gillet, M., Jarnjak, S., De Sousa Alves, P.M., Louahed, J., Brichard, V.G., and Lehmann, F.F.

Published
2016
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24. Reappraisal of Laennec's capsule

Author

Shirata, C., Kokudo, T., Gillet, M., Uldry, E., Demartines, N., Kokudo, N., Hasegawa, K., and Halkic, N.

Subjects
Humans, Liver/surgery, Membranes/surgery, Peritoneal Cavity/surgery, Portal Vein/surgery, Anatomy, Glisson, Hepatectomy, Laennec, Liver parenchyma
Abstract

No abstract available

Published
2020

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