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Your search keyword '"GARFIELD-VTE registry"' showing total 3 results
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3 results on '"GARFIELD-VTE registry"'

1. Isolated Distal Deep Vein Thrombosis: Perspectives from the GARFIELD-VTE Registry

Author

Schellong, S, Goldhaber, S, Weitz, J, Ageno, W, Bounameaux, H, Turpie, A, Angchaisuksiri, P, Haas, S, Goto, S, Zaghdoun, A, Farjat, A, Nielsen, J, Kayani, G, Mantovani, L, Prandoni, P, Kakkar, A, Schellong S. M., Goldhaber S. Z., Weitz J. I., Ageno W., Bounameaux H., Turpie A. G. G., Angchaisuksiri P., Haas S., Goto S., Zaghdoun A., Farjat A., Nielsen J. D., Kayani G., Mantovani L. G., Prandoni P., Kakkar A. K., Schellong, S, Goldhaber, S, Weitz, J, Ageno, W, Bounameaux, H, Turpie, A, Angchaisuksiri, P, Haas, S, Goto, S, Zaghdoun, A, Farjat, A, Nielsen, J, Kayani, G, Mantovani, L, Prandoni, P, Kakkar, A, Schellong S. M., Goldhaber S. Z., Weitz J. I., Ageno W., Bounameaux H., Turpie A. G. G., Angchaisuksiri P., Haas S., Goto S., Zaghdoun A., Farjat A., Nielsen J. D., Kayani G., Mantovani L. G., Prandoni P., and Kakkar A. K.

Abstract

Isolated distal deep vein thrombosis (IDDVT) represents up to half of all lower limb DVT. This study investigated treatment patterns and outcomes in 2,145 patients with IDDVT in comparison with those with proximal DVT (PDVT; n = 3,846) and pulmonary embolism (PE; n = 4,097) enrolled in the GARFIELD-VTE registry. IDDVT patients were more likely to have recently undergone surgery (14.6%) or experienced leg trauma (13.2%) than PDVT patients (11.0 and 8.7%, respectively) and PE patients (12.7 and 4.5%, respectively). Compared with IDDVT, patients with PDVT or PE were more likely to have active cancer (7.2% vs. 9.9% and 10.3%). However, influence of provoking factors on risk of recurrence in IDDVT remains controversial. Nearly all patients (IDDVT, PDVT, and PE) were given anticoagulant therapy. In IDDVT, PDVT, and PE groups the proportion of patients receiving anticoagulant therapy was 61.4, 73.9, and 81.1% at 6 months and 45.8, 54.7, and 61.9% at 12 months. Over 12 months, the incidence of all-cause mortality, cancer, and recurrence was significantly lower in IDDVT patients than PDVT patients (hazard ratio [HR], 0.61 [95% confidence interval [CI], 0.48-0.77]; sub-HR [sHR], 0.60 [95% CI, 0.39-0.93]; and sHR, 0.76 [95% CI, 0.60-0.97]). Likewise, risk of death and incident cancer was significantly (both p < 0.05) lower in patients with IDDVT compared with PE. This study reveals a global trend that most IDDVT patients as well as those with PDVT and PE are given anticoagulant therapy, in many cases for at least 12 months.

Published
2019

2. Upper Extremity DVT versus Lower Extremity DVT: Perspectives from the GARFIELD-VTE Registry

Author

Sebastian Schellong, Walter Ageno, Paolo Prandoni, Audrey Zaghdoun, Pantep Angchaisuksiri, Ajay K. Kakkar, Gloria Kayani, Alfredo E. Farjat, Harald Darius, Alexander G.G. Turpie, Shinya Goto, Lorenzo G. Mantovani, Joern Dalsgaard Nielsen, Samuel Z. Goldhaber, Henri Bounameaux, Jeffrey I. Weitz, Sylvia Haas, Ageno, W, Haas, S, Weitz, J, Goldhaber, S, Turpie, A, Goto, S, Angchaisuksiri, P, Dalsgaard Nielsen, J, Kayani, G, Farjat, A, Zaghdoun, A, Schellong, S, Bounameaux, H, Mantovani, L, Prandoni, P, Darius, H, and Kakkar, A

Subjects
Male, 0301 basic medicine, medicine.medical_treatment, Administration, Oral, direct oral anticoagulant, 030204 cardiovascular system & hematology, 0302 clinical medicine, Recurrence, Prevalence, Prospective Studies, Registries, Young adult, Prospective cohort study, Stroke, Aged, 80 and over, Venous Thrombosis, ddc:616, upper extremity deep vein thrombosis, Hematology, Middle Aged, Hospitalization, Lower Extremity, Female, GARFIELD-VTE registry, Central venous catheter, Adult, lower extremity deep vein thrombosis, venous thromboembolism, Catheterization, Central Venous, medicine.medical_specialty, Adolescent, Upper Extremity, Young Adult, 03 medical and health sciences, Internal medicine, medicine, Humans, Upper Extremity Deep Vein Thrombosis, Aged, business.industry, Anticoagulants, Upper extremity deep vein thrombosis, Cancer, Bleed, medicine.disease, Confidence interval, 030104 developmental biology, direct oral anticoagulant, GARFIELD-VTE registry, lower extremity deep vein thrombosis, upper extremity deep vein thrombosis, venous thromboembolism, business
Abstract

Upper extremity deep vein thrombosis (UEDVT) is less common than lower extremity DVT (LEDVT) and consequently less well characterized. This study compared clinical characteristics and 1-year outcomes between 438 UEDVT patients and 7,602 LEDVT patients recruited in the GARFIELD-VTE registry. UEDVT patients were significantly more likely to have a central venous catheter than those with LEDVT (11.5% vs. 0.5%; p

Published
2019

3. Isolated Distal Deep Vein Thrombosis: Perspectives from the GARFIELD-VTE Registry

Author

Lorenzo G. Mantovani, Audrey Zaghdoun, Gloria Kayani, Walter Ageno, Paolo Prandoni, Samuel Z. Goldhaber, Sebastian Schellong, Alexander G.G. Turpie, Pantep Angchaisuksiri, Alfredo E. Farjat, Joern Dalsgaard Nielsen, Jeffrey I. Weitz, Sylvia Haas, Henri Bounameaux, Shinya Goto, Ajay K. Kakkar, Schellong, S, Goldhaber, S, Weitz, J, Ageno, W, Bounameaux, H, Turpie, A, Angchaisuksiri, P, Haas, S, Goto, S, Zaghdoun, A, Farjat, A, Nielsen, J, Kayani, G, Mantovani, L, Prandoni, P, and Kakkar, A

Subjects
0301 basic medicine, Adult, Male, Risk, medicine.medical_specialty, Deep vein, 030204 cardiovascular system & hematology, Aged, Aged, 80 and over, Anticoagulants, Female, Humans, Incidence, Middle Aged, Prospective Studies, Pulmonary Embolism, Recurrence, Registries, Treatment Outcome, Venous Thromboembolism, Venous Thrombosis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Deep vein thrombosis, 80 and over, Medicine, isolated distal deep vein thrombosi, Prospective cohort study, isolated distal deep vein thrombosis, Stroke, ddc:616, business.industry, Incidence (epidemiology), Hazard ratio, deep vein thrombosi, Hematology, medicine.disease, Thrombosis, Confidence interval, Pulmonary embolism, ddc, 12-month observational study, 030104 developmental biology, medicine.anatomical_structure, 12-month observational study, deep vein thrombosis, GARFIELD-VTE registry, isolated distal deep vein thrombosis, Adult, Aged, Aged, 80 and over, Anticoagulants, Female, Humans, Incidence, Male, Middle Aged, Prospective Studies, Pulmonary Embolism, Recurrence, Registries, Risk, Treatment Outcome, Venous Thromboembolism, Venous Thrombosis, business, GARFIELD-VTE registry
Abstract

Isolated distal deep vein thrombosis (IDDVT) represents up to half of all lower limb DVT. This study investigated treatment patterns and outcomes in 2,145 patients with IDDVT in comparison with those with proximal DVT (PDVT; n = 3,846) and pulmonary embolism (PE; n = 4,097) enrolled in the GARFIELD-VTE registry. IDDVT patients were more likely to have recently undergone surgery (14.6%) or experienced leg trauma (13.2%) than PDVT patients (11.0 and 8.7%, respectively) and PE patients (12.7 and 4.5%, respectively). Compared with IDDVT, patients with PDVT or PE were more likely to have active cancer (7.2% vs. 9.9% and 10.3%). However, influence of provoking factors on risk of recurrence in IDDVT remains controversial. Nearly all patients (IDDVT, PDVT, and PE) were given anticoagulant therapy. In IDDVT, PDVT, and PE groups the proportion of patients receiving anticoagulant therapy was 61.4, 73.9, and 81.1% at 6 months and 45.8, 54.7, and 61.9% at 12 months. Over 12 months, the incidence of all-cause mortality, cancer, and recurrence was significantly lower in IDDVT patients than PDVT patients (hazard ratio [HR], 0.61 [95% confidence interval [CI], 0.48–0.77]; sub-HR [sHR], 0.60 [95% CI, 0.39–0.93]; and sHR, 0.76 [95% CI, 0.60–0.97]). Likewise, risk of death and incident cancer was significantly (both p

Published
2019

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