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RESUMO Objetivou-se estimar a associação fenotípica entre a eficiência alimentar e o ganho em acabamento de carcaça de touros jovens da raça Nelore. Utilizaram-se informações de 98 touros jovens da raça Nelore, participantes de duas provas de eficiência alimentar que empregaram o sistema de cochos eletrônicos Growsafe®, as quais foram realizadas nos anos de 2015 e 2016, na fazenda Capim Branco, da Universidade Federal de Uberlândia. As provas de eficiência alimentar tiveram duração de 91 dias, sendo 21 dias de adaptação e 70 dias de avaliação. Os animais apresentavam idade média ao início e ao término do confinamento de 19,98 e 22,16 meses e peso inicial e final médio de 428,17 e 542,27kg, respectivamente. Verificou-se que os animais mais eficientes depositaram menos gordura, e os animais menos eficientes depositaram mais gordura durante o período de avaliação em confinamento. Observou-se que há uma associação fenotípica de baixa magnitude (0,29) entre o consumo alimentar residual (CAR) e o ganho em acabamento de carcaça (GACAB). Assim, pode-se inferir que, ao serem selecionados menores valores de CAR, haverá alguma interferência negativa em GACAB. Concluiu-se que animais mais eficientes (CAR negativo) podem apresentar menor deposição de gordura subcutânea, influenciando na qualidade de carcaça de bovinos da raça Nelore.

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world and the third leading cause of cancer-related death. In this study, we sought to assess the outcome of patients with HCC who underwent orthotopic liver transplantation (OLT) in a center in the northeast of Brazil. Between May 2002 and July 2008, 294 OLTs were performed at our center. In 45 patients, HCC was confirmed by histological examination of the explant. Patients were predominantly men of ages ranging from 14-67 years. Hepatitis C virus was involved in 55.4% of the cases. Alpha fetoprotein (AFP) levels were normal in 65.2% of the patients and surpassed 100 ng/mL in only 10.4%. The median waiting time on the list was 10 months. Seventeen patients (37.7%) presented a solitary nodule, 19 (42.2%) had 2 or 3 nodules, and 9 patients (20%) had more than 3 nodules. The maximal diameter of the largest tumor was3 cm in 26 patients (57.7%) and exceeded 5 cm in 6 patients (13.3%). Ten tumors were well differentiated, 32 were moderately differentiated, and 3 were poorly differentiated. Eleven tumors showed microvascular invasion. There have been 4 tumor recurrences. There was an association between microvascular invasion and tumor recurrence with a statistically significant relative risk. In conclusion, OLT is an excellent option for patients with HCC. The recurrence rate was low (10%). However, we believe that more prospective studies are needed about OLT beyond the Milan criteria because our study suggested that microvascular invasion may be more important than tumor size or number.

Sequential or domino liver transplantation is a well-established procedure for patients with familial amyloidotic polyneuropathy (FAP). Donation for domino liver transplantation imposed the resection of the inferior vena cava along with the liver, requiring complete suprarenal vena cava clamping and usually the use of venovenous bypass. We describe a successful case in which it was possible to perform the FAP hepatectomy by the piggyback technique.

Belzer and Collins are solutions used in liver transplantation. The purpose of this study was to compare liver function after utilization of two different schemes of graft preservation using both solutions. Between December 2004 and September 2005, 43 liver transplantations were performed. Twenty-three of these used 2 L of Collins solution and 2 L of Belzer solution as the preservation solution. The others used three L of Collins and 1 L of Belzer solution as the preservation solution. The cold ischemia time of both groups was similar. We analyzed liver function using the serum ALT, AST, bilirubin and international normalized ratio. On the first day after the transplantation, the level of international normalized ratio of the group of patients that used 1 L of Belzer was significantly higher than the other group (P.05). The levels of ALT, AST, and bilirubin were not different on day 7 after transplantation. We concluded that using only 1 L of Belzer solution is as efficient with the advantage that it is less expensive.