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2. Correction to: Mesoglycan for pain control after open excisional HAEMOrrhoidectomy (MeHAEMO): an observational multicentre study on behalf of the Italian Society of Colorectal Surgery (SICCR)
- Author
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G. Gallo, S. Di Saverio, G. Clerico, A . Sturiale, M. Manigrasso, A. Realis Luc, M. Trompetto, G. Sammarco, and the MeHAEMO Working Group
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Surgery ,RD1-811 - Abstract
An amendment to this paper has been published and can be accessed via the original article.
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- 2020
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3. Outcomes of gynecologic cancer surgery during the COVID-19 pandemic: an international, multicenter, prospective CovidSurg-Gynecologic Oncology Cancer study
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Nepogodiev, Dmitri, Siaw-Acheampong, Kwabena, Benson, Ruth A., Bywater, Edward, Chaudhry, Daoud, Dawson, Brett E., Evans, Jonathan P., Glasbey, James C., Gujjuri, Rohan R., Heritage, Emily, Jones, Conor S., Kamarajah, Sivesh K., Khatri, Chetan, Khaw, Rachel A., Keatley, James M., Knight, Andrew, Lawday, Samuel, Li, Elizabeth, Mann, Harvinder S., Marson, Ella J., McLean, Kenneth A., Mckay, Siobhan C., Mills, Emily C., Pellino, Gianluca, Picciochi, Maria, Taylor, Elliott H., Tiwari, Abhinav, Simoes, Joana FF., Trout, Isobel M., Venn, Mary L., Wilkin, Richard JW., Bhangu, Aneel, Abbott, Tom EF., Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O., Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Alshryda, Sattar, Arnaud, Alexis P., Augestad, Knut Magne, Ayasra, Faris, Azevedo, José, Bankhead-Kendall, Brittany K., Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Minaya-Bravo, Ana, Breen, Kerry A., Bretherton, Chris, Buarque, Igor Lima, Burke, Joshua, Caruana, Edward J., Chaar, Mohammad, Chakrabortee, Sohini, Christensen, Peter, Cox, Daniel, Cukier, Moises, Cunha, Miguel F., Davidson, Giana H., Desai, Anant, Di Saverio, Salomone, Drake, Thomas M., Edwards, John G., Elhadi, Muhammed, Emile, Sameh, Farik, Shebani, Fiore, Marco, Fitzgerald, J Edward, Ford, Samuel, Garmanova, Tatiana, Gallo, Gaetano, Ghosh, Dhruva, Ataíde Gomes, Gustavo Mendonça, Grecinos, Gustavo, Griffiths, Ewen A., Gruendl, Magdalena, Halkias, Constantine, Harrison, Ewen M., Hisham, Intisar, Hutchinson, Peter J., Hwang, Shelley, Isik, Arda, Jenkinson, Michael D., Jonker, Pascal, MA Kaafarani, Haytham, Keller, Debby, Kolias, Angelos, Kruijff, Schelto, Lawani, Ismail, Lederhuber, Hans, Leventoglu, Sezai, Litvin, Andrey, Loehrer, Andrew, Löffler, Markus W., Lorena, Maria Aguilera, Modolo, Maria Marta, Major, Piotr, Martin, Janet, Mashbari, Hassan N., Mazingi, Dennis, Metallidis, Symeon, Mohan, Helen M., Moore, Rachel, Moszkowicz, David, Moug, Susan, Ng-Kamstra, Joshua S., Maimbo, Mayaba, Negoi, Ionut, Niquen, Milagros, Ntirenganya, Faustin, Olivos, Maricarmen, Oussama, Kacimi, Outani, Oumaima, Parreno-Sacdalanm, Marie Dione, Pata, Francesco, Perez Rivera, Carlos Jose, Pinkney, Thomas D., van der Plas, Willemijn, Pockney, Peter, Qureshi, Ahmad, Radenkovic, Dejan, Ramos-De la Medina, Antonio, Richards, Toby, Roberts, Keith, Roslani, April C., Rutegård, Martin, Segura-Sampedro, Juan José, Santos, Irène, Satoi, Sohei, Sayyed, Raza, Schache, Andrew, Schnitzbauer, Andreas A., Seyi-Olajide, Justina O., Sharma, Neil, Shaw, Catherine A., Shaw, Richard, Shu, Sebastian, Soreide, Kjetil, Spinelli, Antonino, Stewart, Grant D., Sund, Malin, Sundar, Sudha, Tabiri, Stephen, Townend, Philip, Tsoulfas, Georgios, van Ramshorst, Gabrielle H., Vidya, Raghavan, Vimalachandran, Dale, Warren, Oliver J., Wedderburn, Duane, Wright, Naomi, Booth, Lesley, Barker, Neil, Cooke, Shirley, Doré, Suzanne, Horwood, Nigel, Runigamugabo, Emmy, Weir, Carrie Tierney, Dajti I, Albania, C, Allemand, LA, Boccalatte, M, Figari, M, Lamm, J, Larrañaga, C, Marchitelli, F, Noll, D, Odetto, M, Perrotta, J, Saadi, L, Zamora, Ballester, A.M., KE, Tapper, N, Zeff, JI, Valenzuela, C, Alurralde, J, Anastasio, Perez de Nucci A, Apas, EL, Caram, D, Eskinazi, JP, Mendoza, M, Usandivaras, R, Badra, A, Esteban, JS, García, PM, García, JI, Gerchunoff, Lucchini, S.M., NIgra, M.A., L, Vargas, T, Hovhannisyan, A, Stepanyan, CE, Vasey, EGR, Watson, C, Ip, J, Kealey, CSH, Lim, S, Sengupta, S, Ward, E, Wong, T, Gould, R, Gourlay, B, Griffiths, S, Gananadha, M, McLaren, J, Cecire, N, Joshi, S, Salindera, A, Sutherland, JH, Ahn, G, Charlton, S, Chen, N, Gauri, R, Hayhurst, S, Jang, F, Jia, C, Mulligan, W, Yang, G, Ye, H, Zhang, M, Ballal, D, Gibson, D, Hayne, H, McMillan, J, Moss, MJ, Pugliese, T, Richards, YTN, Seow, A, Thian, P, Viswambaram, UG, Vo, J, Bennetts, T, Bright, Brooke-Smith, M., R, Fong, B, Gricks, L, Huang, YH, 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Freyschlag, M, Kafka, F, Messner, D, Öfner, I, Tsibulak, S, Holawe, M, Zimmermann, K, Emmanuel, M, Grechenig, R, Gruber, M, Harald, L, Öhlberger, J, Presl, A, Wimmer, İ, Namazov, E, Samadov, D, Barker, R, Boyce, S, Corbin, A, Doyle, A, Eastmond, R, Gill, A, Haynes, S, Millar, M, O’Shea, G, Padmore, N, Paquette, E, Phillips, John S, St., K, Walkes, J, Abeloos, Backer T, De, Ceulaer J, De, C, Dick, Diez-Fraile, A., P, Lamoral, C, Spaas, W, Ceelen, P, Pattyn, D, Van de putte, Nieuwenhove Y, Van, Ramshorst G, Van, Willaert, W., Bazzett-Matabele, L., SP, Chiyapo, Ramogola-Masire, D., G, Ramontshonyana, A, Seiphetlheng, P, Vuylsteke, EA, Abdallah, Júnior S, Aguiar, G, Baiocchi, GB, Carvalho, FJF, Coimbra, LP, Kowalski, F, Makdissi, N, Marques, T, Marques, Santos S, Soares Dos, Gonçalves B, Tirapelli, JG, Vartanian, Reis R, Dos, P, Camara, Lima RK, De, Giustina E, Della, PV, Hoffmann, A, Gatti, C, Nardi, R, Oliva, L, Nacif, Ferro C, Carvalho, Ataíde G, Gomes Mendonça, Buarque I, Lima, A, Lira dos Santos Leite, Pol-Fachin, L., Bezerra T, Santos, Ramos da Silva A, Maylson, de Araújo Silvestre D, Windson, Barros A, Vieira, L, Campbell, Cicco R, De, I, Cecconello, P, Gregorio, Lima L, Pontual, Junior U, Ribeiro, FR, Takeda, RM, Terra, Teixeira M, Faccini, Kulcsar, M.A.V., LL, Matos, KS, Nunes, G, Laporte, M, Salem, Awada J, Barakat, TR, Ijichi, NJ, Kim, A, Marreiro, B, Muller, R, Nunes, B, Bodanese, ER, Eidt, JC, Isoton, Vieira da Cunha M, Lemos, de Sampaio L, Regina, C, Vendrame, M, Zeni, JA, Zortéa, MR, Zortéa, M, Sokolov, B, Kidane, S, Srinathan, A, Munro, L, Helyer, D, McKeen, M, Boutros, NG, Caminsky, G, Ghitulescu, G, Jamjoum, J, Moon, J, Pelletier, T, Vanounou, S, Wong, D, Cheng, SD, MacNeil, J, Martin, S, Dumitra, A, Kouyoumdjian, S, Schmid, J, Spicer, A, Agarwal, A, Brar, J, Dada, A, Dare, U, Hameed, F, Osman, B, Johnston, C, Russell, G, Groot, A, Persad, H, Pham, M, Wood, M, Ko, L, Rajendran, S, Demyttenaere, R, Garfinkle, C, Brown, A, Karimuddin, N, Lee, J, Liu, Kia T, Madani, Phang, P.T., M, Raval, K, Tom, Abou-Khalil, J., A, Martel, C, Nessim, J, Stevenson, Riyami S, Al, K, Bali, D, Bigam, K, Dajani, A, Dell, MM, Modolo, Nieto P, Ramirez, R, Sepulveda, A, Molero, A, Bolbaran, I, Ruiz, F, Heredia, F, Bellolio, N, Besser, E, Grasset, JO, Guaman, M, Inzunza, MJ, Irarrázaval, C, Jarry, Martinic M, Quintana, Altamirano C, Riquoir, Manqui CA, Romero, Esquide M, Ruiz, Añazco C, Vargas, A, Almeciga, A, Fletcher, A, Merchan, T, Quijano, D, Sanabria, Arias-Amézquita, F., C, Cétares, Murgueitio N, Cortes, Gomez-Mayorga, J.L., Herrera-Almario, G., J, Rodriguez, P, Iglesias, LO, Puentes, JA, Calvache, Orozco-Chamorro, C.M., DA, Rojas, Sánchez-Gómez, A., M, Abadia, J, Acosta, Aristizabal J, Angel, A, Bonilla, L, Caicedo, Quiroz PH, Calderon, Bonilla S, Cervera, S, Diaz, H, Facundo, Mora M, Garcia, O, Guevara, L, Guzman, Mora DR, Herrera, Ramirez LJ, Jimenez, C, Lehmann, E, Manrique, I, Mariño, M, Medina, Morales RE, Pinilla, A, Puerto, Horta J, Puerto, M, Quintero, Ferro M, Rey, A, Saénz, D, Santana, W, Serrano, O, Suescun, Sanchez LM, Trujillo, Cuasquen BG, Velasquez, Quevedo J , Bogota, Mendoza, G, Bačić, D, Karlović, D, Kršul, M, Zelić, I, Luksic, M, Mamic, I, Bacic, B, Bakmaz, I, Ćoza, E, Dijan, Z, Katusic, J, Mihanovic, D, Morović, I, Rakvin, H, Almezghwi, K, Arslan, H, Besim, A, Özant, N, Özçay, K, Frantzeskou, N, Gouvas, G, Kokkinos, P, Papatheodorou, I, Pozotou, O, Stavrinidou, A, Yiallourou, L, Martinek, M, Skrovina, M, Straka, I, Szubota, M, Peteja, J, Žatecký, V, Javurkova, J, Klat, S, Antony, T, Avlund, KD, Berg, M, Borre, P, Christensen, MC, Elkjær, A, Ernst, SK, Fensman, M, Haldrup, JL, Harbjerg, LH, Iversen, Jensen, P.T., TD, Jeppesen, DW, Kjaer, HØ, Kristensen, N, Lund, Axelsen S, Maigaard, M, Mekhael, N, Mikic, EB, Ostenfeld, AL, Ebbehøj, P, Krarup, N, Schlesinger, H, Smith, S, Batista, A, Crespo, PJ, Díaz, R, Rivas, Rodriguez-Abreu, J., N, Tactuk, Kassas M, El, W, Omar, A, Tawheed, M, Talaat, A, Abdelsamed, AY, Azzam, H, Salem, A, Seleim, A, Abdelmajeed, M, Abdou, NE, Abosamak, Sayed M, A.L., F, Ashoush, R, Atta, E, Elazzazy, M, Elnemr, Hewalla ME, Elsayed, I, Elsherbini, E, Essam, M, Ewedah, I, Ghallab, E, Hassan, M, Ibrahim, M, Metwalli, M, Mourad, Qatora, M.S., M, Ragab, A, Sabry, H, Saifeldin, A, Samih, Abdelaal A, Samir, S, Shehata, K, Shenit, D, Attia, N, Kamal, N, Osman, Abbas, A.M., Elazeem HAS, Abd, Abd-Elkariem, A.Y., MM, Abdelkarem, S, Alaa, M, Ashraf, A, Ayman, MG, Azizeldine, H, Elkhayat, Mashhour A, Emad, M, Gaber, HM, Hamza, I, Hawal, HF, Hetta, Ali A, K., S, M.elghazaly, MM, Mohammed, FA, Monib, Nageh, M.A., A, Saad, MM, Saad, M, Shahine, EA, Yousof, A, Youssef, El-Deeb, M., M, Fawzy, G, Ghaly, M, Ibraheem, A, Eldaly, E, Esmail, M, ElFiky, A, Nabil, M, Alrahawy, A, Sakr, H, Soliman, H, Soltan, G, Amira, I, Sallam, M, Sherief, A, Sherif, A, Abdelrahman, H, Aboulkassem, R, Hamdy, A, Morsi, G, Sherif, H, Abdeldayem, Salama I, Abdelkader, M, Balabel, Y, Fayed, AE, Sherif, R, Elmorsi, S, Emile, B, Refky, S, Abd-elsalam, H, Badr, M, Elbahnasawy, M, Elzoghby, M, Essa, Badr S, Gamal, A, Ghoneim, O, Hamad, M, Hamada, M, Hammad, A, Hawila, Morsy, M.S., S, Salman, S, Sarsik, K, Bekele, JH, Kauppila, E, Sarjanoja, O, Helminen, H, Huhta, C, Beyrne, L, Jouffret, L, Lugans, Marie-Macron, L., E, Chouillard, Simone B, De, F, Fredon, A, Roux, J, Bettoni, S, Dakpé, B, Devauchelle, N, Lavagen, S, Testelin, S, Boucher, R, Breheret, A, Gueutier, A, Kahn, Kün-Darbois, J., A, Barrabe, Z, Lakkis, A, Louvrier, S, Manfredelli, P, Mathieu, A, Chebaro, V, Drubay, M, El amrani, C, Eveno, K, Lecolle, G, Legault, L, Martin, G, Piessen, FR, Pruvot, S, Truant, P, Zerbib, Q, Ballouhey, B, Barrat, L, Fourcade, J, Laloze, H, Salle, A, Taibi, J, Tricard, J, Usseglio, D, Bergeat, A, Merdrignac, Roy B, Le, LO, Perotto, A, Scalabre, H, Gornes, C, Vaysse, K, Vergriete, A, Aimé, A, Ezanno, B, Malgras, AP, Arnaud, E, Fustec, V, Lavoue, C, Tesson, P, Bouche, S, Tzedakis, E, Cotte, O, Glehen, J, Lifante, L, Bendjemar, H, Braham, L, Charre, Arbi N, El, L, Morel-chevillet, A, Police, V, Villefranque, E, Volpin, A, D’Urso, E, Felli, D, Mutter, P, Pessaux, B, Seeliger, Y, Barbé, J, Bardet, E, Barret, R, Berry, G, Boddaert, S, Bonnet, E, Brian, N, Cathala, X, Cathelineau, C, Denet, D, Fuks, D, Gossot, M, Grigoroiu, A, Laforest, Levy-Zauberman, Y., Louis-Sylvestre, C., P, Macek, A, Mombet, A, Moumen, G, Pourcher, F, Rozet, Salas R, Sanchez, A, Seguin-givelet, E, Tribillon, V, Crenn, Vergie S, De, E, Duchalais, F, Espitalier, C, Ferron, H, Fragnaud, O, Malard, N, Regenet, J, Rigaud, Y, Varenne, D, Waast, U, Bork, M, Distler, J, Fritzmann, J, Kirchberg, C, Praetorius, C, Riediger, J, Weitz, T, Welsch, P, Wimberger, K, Beyer, C, Kamphues, J, Lauscher, FN, Loch, C, Schineis, M, Albertsmeier, M, Angele, A, Kappenberger, H, Niess, T, Schiergens, J, Werner, R, Becker, J, Jonescheit, J, Doerner, R, Seiberth, I, Pergolini, D, Reim, J, Herzberg, H, Honarpisheh, T, Strate, C, Boeker, I, Hakami, J, Mall, P, Liokatis, W, Smolka, N, Vassos, Mannheim, K, Nowak, T, Reinhard, F, Hölzle, A, Modabber, P, Winnand, M, Anthuber, E, Shiban, B, Sommer, F, Sommer, S, Wolf, H, Howaldt, M, Knitschke, P, Kauffmann, S, Wolfer, J, Kleeff, K, Lorenz, C, Michalski, U, Ronellenfitsch, Saale, Schneider R., E, Bertolani, A, Königsrainer, MW, Löffler, M, Quante, C, Steidle, L, Überrück, C, Yurttas, CS, Betz, J, Bewarder, A, Böttcher, S, Burg, C, Busch, M, Dreimann, KH, Frosch, M, Gosau, A, Heuer, J, Izbicki, TO, Klatte, D, Koenig, N, Moeckelmann, C, Nitschke, D, Perez, M, Priemel, A, Reiter, R, Smeets, U, Speth, M, Stangenberg, S, Thole, FG, Uzunoglu, L, Viezens, T, Vollkommer, N, Zeller, MJ, Battista, K, Gillen, A, Hasenburg, S, Krajnak, VC, Linz, R, Schwab, Amo-Antwi, K., A, Appiah-kubi, T, Konney, A, Tawiah, S, Boatey, A, Issaka, Korsah, M.A., M, Sheriff, K, Angelou, D, Haidopoulos, A, Rodolakis, P, Antonakis, K, Bramis, L, Chardalias, I, Contis, N, Dafnios, D, Dellaportas, G, Fragulidis, A, Gklavas, M, Konstadoulakis, N, Memos, I, Papaconstantinou, A, Polydorou, T, Theodosopoulos, A, Vezakis, MI, Antonopoulou, DK, Manatakis, N, Tasis, N, Arkadopoulos, N, Danias, P, Economopoulou, M, Frountzas, P, Kokoropoulos, A, Larentzakis, N, Michalopoulos, C, Nastos, S, Parasyris, E, Pikoulis, J, Selmani, T, Sidiropoulos, P, Vassiliu, K, Bouchagier, S, Klimopoulos, D, Paspaliari, G, Stylianidis, D, Akrivou, K, Baxevanidou, K, Bouliaris, P, Chatzikomnitsa, G, Delinasios, C, Doudakmanis, M, Efthimiou, A, Giaglaras, C, Kalfountzos, C, Kolla, G, Koukoulis, K, Zervas, S, Zourntou, I, Baloyiannis, A, Diamantis, E, Gkrinia, J, Hajiioannou, C, Korais, O, Koukoura, K, Perivoliotis, A, Saratziotis, C, Skoulakis, D, Symeonidis, K, Tepetes, G, Tzovaras, D, Zacharoulis, V, Alexoudi, K, Antoniades, I, Astreidis, P, Christidis, D, Deligiannidis, T, Grivas, O, Ioannidis, I, Kalaitsidou, L, Loutzidou, A, Mantevas, D, Michailidou, E, Nikolaidou, S, Papadopoulou, K, Paraskevopoulos, S, Politis, A, Stavroglou, D, Tatsis, I, Tilaveridis, K, Vahtsevanos, G, Venetis, I, Karaitianos, T, Tsirlis, K, Dinas, Margioula-Siarkou, C., S, Petousis, E, Baili, A, Charalabopoulos, T, Liakakos, D, Schizas, E, Spartalis, A, Syllaios, C, Zografos, C, Anthoulakis, Christou, C.D., V, Papadopoulos, A, Tooulias, D, Tsolakidis, G, Tsoulfas, D, Zouzoulas, E, Athanasakis, E, Chrysos, I, Tsiaoussis, S, Xenaki, E, Xynos, Duarte A, Barrios, Muralles I, Lopez, MJ, Lowey, AL, Portilla, G, Recinos, JYK, Chan, Chan, S.M., CCN, Chong, K, Futaba, Ho, M.F., SF, Hon, RWH, Lau, TWC, Mak, CF, Ng, CSH, Ng, KKC, Ng, SSM, Ng, AYB, Teoh, JY, Teoh, CC, Foo, B, Banky, N, Suszták, S, Misra, P, Pareek, JR, Vishnoi, S, Ambre, V, Balasubiramaniyan, P, Chappity, I, Chaudhary, L, Colney, MK, Das, M, Imaduddin, A, Jain, SK, Jena, M, Kar, S, Mandal, A, Mishra, SS, Mishra, TS, Mishra, JK, Mitra, Y, Mittal, DK, Muduly, P, Nayak, PK, Parida, P, Pradhan, DK, Rajan, E, Rebba, DK, Samal, A, Singh, M, Sultania, SP, Agarwal, A, Agrawal, RK, Arora, J, 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M, Mohammed, G, Tahhan, V, Valtzoglou, N, Blencowe, P, Eskander, K, Gash, L, Gourbault, M, Hanna, TA, Maccabe, B, Main, J, Olivier, C, Newton, S, Roswadowski, N, Ryan, E, Teh, D, West, H, Al-omishy, M, Baig, H, Bates, Taranto G, Di, K, Dickson, N, Dunne, C, Gill, D, Howe, D, Jeevan, A, Khajuria, Martin-Ucar, A., K, McEvoy, P, Naredla, S, Robertson, M, Sait, DR, Sarma, S, Shanbhag, T, Shortland, S, Simmonds, J, Skillman, N, Tewari, G, Walton, Akhtar, M.A., A, Brunt, J, McIntyre, K, Milne, MM, Rashid, A, Sgrò, KE, Stewart, A, Turnbull, Abou-Foul, A.K., G, Gossedge, S, O’Donnell, F, Oldfield, S, Thomson, Gonzalez M, Aguilar, S, Talukder, C, Boyle, D, Fernando, K, Gallagher, A, Laird, D, Tham, M, Bath, P, Basnyat, H, Davis, P, Montauban, A, Shrestha, K, Agarwal, T, Arif, C, Magee, T, Nambirajan, S, Powell, R, Vinayagam, I, Flindall, A, Hanson, V, Mahendran, S, Green, M, Lim, L, MacDonald, V, Miu, L, Onos, K, Sheridan, R, Young, F, Alam, O, Griffiths, C, Houlden, VS, Kolli, AK, Lala, S, Leeson, R, Peevor, Z, Seymour, E, Consorti, R, Gonzalez, R, Grolman, Kwan-Feinberg, R., T, Liu, O, Merzlikin, Francisco, San, A, Brown, Z, Cooper, S, Hirji, J, Jolissaint, D, Mahvi, B, Okafor, CP, Raut, V, Roxo, A, Salim, S, Bessen, L, Chen, L, Dagrosa, K, Fay, C, Fleischer, R, Hasson, E, Henderson, M, Leech, A, Loehrer, C, Markey, J, Paydarfar, K, Rosenkranz, K, Telma, N, Tocci, Wilkinson-Ryan, I., M, Bokenkamp, K, Brown, D, Fleming, C, Heron, C, Hill, H, Kay, E, Leede, K, McElhinney, KA, Olson, EC, Osterberg, C, Riley, P, Srikanth, J, Barbour, D, Blazer, GA, DiLalla, O, Fayanju, ES, Hwang, R, Kahmke, H, Kazaure, A, Lazarides, W, Lee, M, Lidsky, C, Menendez, D, Moris, J, Plichta, MC, Pradhan, L, Puscas, HE, Rice, D, Rocke, L, Rosenberger, R, Scheri, Smith, B.D., Stang, M.T., L, Tolnitch, K, Turnage, J, Visgauss, FS, Walton, T, Watts, S, Zani, J, Farma, K, Cardona, MC, Russell, J, Clark, D, Kwon, N, Goel, J, Kronenfeld, B, Bigelow, E, Etchill, Gabre-Kidan, A., H, Jenny, A, Kent, MR, Ladd, C, Long, H, Malapati, A, Margalit, S, Rapaport, J, Rose, K, Stevens, L, Tsai, D, Vervoort, P, Yesantharao, A, Dehal, D, Klaristenfeld, K, Huynh, H, Kaafarani, L, Naar, M, Qadan, L, Brown, I, Ganly, JE, Mullinax, N, Alpert, C, Gillezeau, Miles DDS MD, F.A.C.S.B.A., E, Taioli, DE, Cha, E, Gleeson, C, Horn, U, Sarpel, N, Gusani, J, Hazelton, J, Maines, JS, Oh, A, Ssentongo, P, Ssentongo, A, Bhama, K, Colling, M, Najarian, M, Azam, A, Choudhry, W, Marx, Y, Abedin, G, Arzumanov, R, Chokshi, S, Gabrilovich, N, Glass, E, Kalyoussef, Parvin-Nejad, F.P., D, Roden, J, Stein, Suarez-Ligon, A., G, Tsui, K, Zhao, J, Fleming, A, Fuson, J, Gigliotti, A, Ovaitt, Y, Ying, MK, Abel, V, Andaya, K, Bigay, Boeck, M.A., H, Chern, C, Corvera, El-Sayed, I., A, Glencer, P, Ha, Hamilton, B.C.S., C, Heaton, K, Hirose, Jablons, D.M., KS, Kirkwood, LZ, Kornblith, JR, Kratz, RH, Lee, PN, Miller, EK, Nakakura, Nunez-Garcia, B., RJ, O’Donnell, D, Ozgediz, P, Park, B, Robinson, A, Sarin, B, Sheu, MG, Varma, KC, Wai, R, Wustrack, MJ, Xu, M, Zimel, D, CA) Beswick, J, Goddard, J, Manor, J, Song, Springs/Loveland, Denver/Colorado, A, Cioci, W, Pavlis, K, Rakoczy, G, Ruiz, R, Saberi, T, Fullmer, C, Gaskill, N, Gross, K, Kiong, CL, Roland, SN, Zafar, M, Abdallah, A, Abouassi, E, Aigbivbalu, M, Almasri, J, Eid, B, George, G, Kulkarni, H, Marwan, M, Mehdi, Andrés M, San, J, Sundaresan, SG, Aoun, VS, Ban, HH, Batjer, K, Bosler, J, Caruso, B, Sumer, D, Abbott, A, Acher, T, Aiken, J, Barrett, E, Foley, PB, Schwartz, AT, Hawkins, A, Maiga, NM, Ruzgar, M, Sion, S, Ullrich, J, Laufer, S, Scasso, Al-Naggar, H., Al-Shehari, M., A, Almassaudi, M, Alsayadi, R, Alsayadi, M, Nahshal, S, Shream, S, AL-Ameri, M, Aldawbali, Fotopoulou, Christina, Khan, Tabassum, Bracinik, Juraj, Glasbey, James, Abu-Rustum, Nadeem, Chiva, Luis, Fagotti, Anna, Fujiwara, Keiichi, Ghebre, Rahel, Gutelkin, Murat, Konney, Thomas O., Ng, Joseph, Pareja, Rene, Kottayasamy Seenivasagam, Rajkumar, Sehouli, Jalid, Surappa, Shylasree T.S., and Leung, Elaine
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- 2022
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4. Mechanisms of hiatus failure in prolapse: a multifaceted evaluation
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Wenjin Cheng, James A. Ashton-Miller, Giselle E. Kolenic, Emily M English, John O.L. DeLancey, Anne G. Sammarco, and Luyun Chen
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medicine.medical_specialty ,Contraction (grammar) ,Urology ,030232 urology & nephrology ,Anterior wall ,Hiatus ,Pelvic Floor Muscle ,Pelvic Organ Prolapse ,Article ,Levator hiatus ,03 medical and health sciences ,Imaging, Three-Dimensional ,0302 clinical medicine ,Internal medicine ,Urogenital hiatus ,medicine ,Humans ,Ultrasonography ,030219 obstetrics & reproductive medicine ,Pelvic floor ,business.industry ,Obstetrics and Gynecology ,Pelvic Floor ,Cross-Sectional Studies ,medicine.anatomical_structure ,Case-Control Studies ,Vagina ,Cardiology ,Muscle strength ,Female ,business - Abstract
INTRODUCTION AND HYPOTHESIS: We investigated whether factors influencing pelvic floor hiatal closure are inter-related or independent, hypothesizing that a) hiatus size is moderately correlated with levator defect, pelvic floor muscle strength, and change in hiatus size with contraction; and b) urogenital hiatus (UGH) and levator hiatus (LH) measures are similar in patients with anterior wall (AW) and posterior wall (PW) prolapse. METHODS: This cross-sectional case-control study included subjects with AW prolapse (n=50), PW prolapse (n=50), and normal support (n=50). Hiatus measurements and levator defects were assessed on MRI and vaginal closure force was measured with an instrumented speculum. Pearson correlation coefficients and simple and multivariable linear regression models were performed. RESULTS: During contraction, LH narrowed 47% more in the PW compared to AW group (p=0.001). With straining, LH lengthened 34% more in the PW than AW group (p
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- 2021
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5. A multicentre, open-label, single-arm phase II trial of the efficacy and safety of sclerotherapy using 3% polidocanol foam to treat second-degree haemorrhoids (SCLEROFOAM)
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G. Gallo, R. Pietroletti, E. Novelli, A. Sturiale, R. Tutino, P. Lobascio, R. Laforgia, E. Moggia, M. Pozzo, M. Roveroni, V. Bianco, A. Realis Luc, A. Giuliani, E. Diaco, G. Naldini, M. Trompetto, R. Perinotti, and G. Sammarco
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Bleeding haemorrhoids ,Haemorrhoidal disease ,Polidocanol foam ,Safety ,Sclerotherapy ,Gastroenterology ,Surgery - Abstract
Background The aim of the present study was to evaluate the efficacy and safety of 3% polidocanol foam for treating 2nd-degree haemorrhoids. Methods A multicentre, open-label, single-arm, phase 2 trial involving 10 tertiary referral centres for haemorrhodal disease (HD) was performed. Between January and June 2019, patients with 2nd-degree haemorrhoids were prospectively included in this study. The primary outcome was to establish the success rate after one sclerotherapy session in terms of complete resolution of bleeding episodes one week after the injection. The Hemorrhoidal Disease Symptom Score (HDSS), the Short Health Scale for HD (SHS-HD) score and the Vaizey incontinence score were used to assess symptoms and their impact on quality of life and continence. Pain after the procedure, subjective symptoms and the amount and type of painkillers used were recorded. Patients were followed up for 1 year. Results There were 183 patients [111 males; 60.7%, mean age 51.3 ± 13.5 (18–75) years]. Complete resolution of bleeding was reached in 125/183 patients (68.3%) at 1 week and the recurrence rate was 12% (15/125). Thirteen patients (7.4%) underwent a second sclerotherapy session, while only 1 patient (1.8%) had to undergo a third session. The overall 1-year success rate was 95.6% (175/183). The HDSS and the SHS score significantly improved from a median preoperative value of 11 and 18 to 0 and 0, respectively (p Conclusions Sclerotherapy with 3% polidocanol foam is a safe, effective, painless, repeatable and low-cost procedure in patients with bleeding haemorrhoids.
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- 2022
6. Geometric analysis of the urethral-vaginal interface curvature in women with and without stress urinary incontinence: A pilot magnetic resonance imaging study
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Christopher X. Hong, John O.L. DeLancey, Anne G. Sammarco, and David Sheyn
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Geometric analysis ,Urology ,Urinary Incontinence, Stress ,Anterior wall ,Urinary incontinence ,Pilot Projects ,Curvature ,Article ,Pelvic Organ Prolapse ,Stress (mechanics) ,Urethra ,medicine ,Humans ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Hymen ,Case-Control Studies ,Female ,Neurology (clinical) ,medicine.symptom ,business ,Nuclear medicine ,Arc length - Abstract
AIMS To evaluate differences in the curvature of the urethral-vaginal interface in women with and without stress urinary incontinence (SUI) using geometric morphometric analysis techniques. METHODS We conducted a pilot case-control study using magnetic resonance imaging (MRI) scans of 18 women with and without SUI. The urethral-vaginal interface at the level of the mid-urethra was fitted with a second-order polynomial regression. The chord length and chord-to-vertex length of the resulting parabolic curve were used to calculate the arc length and radius of a circular arc fitted to the interface curvature. Demographic characteristics and Pelvic Organ Prolapse Quantification (POP-Q) parameters were collected. Subjects were stratified by those with and without SUI, as well as by those with and without anterior wall prolapse beyond 2 cm proximal to the hymen (Aa > -2 cm). RESULTS The radius of the urethral-vaginal interface curvature was not found to be different between subjects with and without SUI (8.8 vs. 9.2 mm, p = 0.53); however, this value was smaller in subjects with Aa > -2 (8.4 vs. 11.9 mm, p = 0.03). The chord length, chord-to-vertex length, and arc length comprising the urethral-vaginal interface curvature were similar between subjects with and without SUI, and between subjects with and without Aa > -2 cm (p > 0.05 for all). CONCLUSIONS In this pilot study population, the radius of the urethral-vaginal interface curvature at the mid-urethra was smaller among women with anterior vaginal wall prolapse beyond 2 cm proximal to the hymen. A difference in the urethral-vaginal interface curvature among women with and without SUI was not found.
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- 2021
7. Historic transvaginal meshes and procedures: what did my patient have done?
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Kristin M Jacobs, Annetta M. Madsen, and Anne G Sammarco
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Surgical repair ,Pelvic organ ,medicine.medical_specialty ,030219 obstetrics & reproductive medicine ,business.industry ,General surgery ,Obstetrics and Gynecology ,Treatment options ,Signs and symptoms ,Prostheses and Implants ,Surgical Mesh ,Pelvic Organ Prolapse ,03 medical and health sciences ,Patient safety ,Gynecologic Surgical Procedures ,Postoperative Complications ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Vagina ,Humans ,Medicine ,Female ,Polygon mesh ,Patient Safety ,business - Abstract
Purpose of review Transvaginal mesh kits were widely used to treat pelvic organ prolapse for over a 10-year period in the early 2000s. Due to safety concerns and FDA regulations, these mesh kits are no longer available for use. Thus, current Obstetricians and Gynecologists are likely to encounter these meshes, but may have no previous experience or exposure to the devices making it difficult to adequately monitor, counsel, and care for patients that underwent these types of procedures. This review highlights the most commonly used transvaginal mesh kit types, provides insight into signs and symptoms related to transvaginal mesh complications, and provides guidance for management of mesh complications. Recent findings Not all transvaginal mesh will give rise to a complication. If complications do occur, treatment options range from conservative observation to total mesh excision. Management must be customized to an individual patient's needs and goals. Summary Transvaginal mesh kits promised increased durability of surgical repair for pelvic organ prolapse. Safety concerns over time caused these kits to no longer be available for use. Practicing Obstetricians and Gynecologists should be aware of the history of transvaginal mesh and the signs and symptoms of mesh complications.
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- 2019
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8. Use of X-ray to Assess Fecal Loading in Patients with Gastrointestinal Symptoms
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Grace Keeney-Bonthrone, Anne G. Sammarco, Sarah Bell, Versha Pleasant, Richard J. Saad, and Mitchell B. Berger
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medicine.medical_specialty ,Past medical history ,Constipation ,Physiology ,business.industry ,Gold standard ,Gastroenterology ,Hepatology ,Logistic regression ,03 medical and health sciences ,Diarrhea ,0302 clinical medicine ,Bloating ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,030211 gastroenterology & hepatology ,medicine.symptom ,business ,Feces - Abstract
There is currently no gold standard for evaluating stool burden in the colon for patients with gastrointestinal symptoms. We aim to examine the relationship between fecal loading on single view abdominal X-ray imaging and gastrointestinal symptoms such as constipation, diarrhea, bloating, and accidental bowel leakage in adult outpatients. This retrospective, cross-sectional study examined patients seen at University of Michigan from 2005 to 2017. Chart review of demographic information, reported gastrointestinal symptoms, past medical history, and abdominal radiographic imaging was performed. Bivariate analysis was performed to assess associations between these characteristics and fecal loading. Factors independently associated with fecal loading were identified using logistic regression. Significance was established at p
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- 2019
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9. Elective cancer surgery in COVID-19–Free surgical pathways during the SARS-cov-2 pandemic: An international, multicenter, comparative cohort study
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James C Glasbey, Dmitri Nepogodiev, Joana Ff Simoes, Omar Omar, Elizabeth Li, Mary L Venn, Mohammad Abou Chaar, Vita Capizzi, Daoud Chaudhry, Anant Desai, Jonathan G Edwards, Jonathan P Evans, Marco Fiore, Jose Flavio Videria, Samuel J Ford, Ian Ganyli, Ewen A Griffiths, Rohan R Gujjuri, Angelos G Kolias, Haytham Ma Kaafarani, Ana Minaya-Bravo, Siobhan C McKay, Helen M Mohan, Keith Roberts, Carlos San Miguel-Méndez, Peter Pockney, Richard Shaw, Neil J Smart, Grant D Stewart, Sudha Sundar, Raghavan Vidya, Aneel A Bhangu, James C Glasbey, Omar Omar, Aneel A Bhangu, Kwabena Siaw-Acheampong, Ruth A Benson, Edward Bywater, Daoud Chaudhry, Brett E Dawson, Jonathan P Evans, James C Glasbey, Rohan R Gujjuri, Emily Heritage, Conor S Jones, Sivesh K Kamarajah, Chetan Khatri, Rachel A Khaw, James M Keatley, Andrew Knight, Samuel Lawday, Elizabeth Li, Harvinder S Mann, Ella J Marson, Kenneth A McLean, Siobhan C McKay, Emily C Mills, Dmitri Nepogodiev, Gianluca Pellino, Maria Picciochi, Elliott H Taylor, Abhinav Tiwari, Joana Ff Simoes, Isobel M Trout, Mary L Venn, Richard Jw Wilkin, Aneel A Bhangu, James C Glasbey, Neil J Smart, Ana Minaya-Bravo, Jonathan P Evans, Gaetano Gallo, Susan Moug, Francesco Pata, Peter Pockney, Salomone Di Saverio, Abigail Vallance, Dale Vimalchandran, Ewen A Griffiths, Sivesh K Kamarajah, Richard Pt Evans, Philip Townend, Keith Roberts, Siobhan McKay, John Isaac, Sohei Satoi, John Edwards, Aman S Coonar, Adrian Marchbank, Edward J Caruana, Georgia R Layton, Akshay Patel, Alessandro Brunelli, Samuel Ford, Anant Desai, Alessandro Gronchi, Marco Fiore, Max Almond, Fabio Tirotta, Sinziana Dumitra, Angelos Kolias, Stephen J Price, Daniel M Fountain, Michael D Jenkinson, Peter Hutchinson, Hani J Marcus, Rory J Piper, Laura Lippa, Franco Servadei, Ignatius Esene, Christian Freyschlag, Iuri Neville, Gail Rosseau, Karl Schaller, Andreas K Demetriades, Faith Robertson, Alex Alamri, Richard Shaw, Andrew G Schache, Stuart C Winter, Michael Ho, Paul Nankivell, Juan Rey Biel, Martin Batstone, Ian Ganly, Raghavan Vidya, Alex Wilkins, Jagdeep K Singh, Dinesh Thekinkattil, Sudha Sundar, Christina Fotopoulou, Elaine Leung, Tabassum Khan, Luis Chiva, Jalid Sehouli, Anna Fagotti, Paul Cohen, Murat Gutelkin, Rahel Ghebre, Thomas Konney, Rene Pareja, Rob Bristow, Sean Dowdy, T S Shylasree, R Kottayasamy Seenivasagam, Joe Ng, Keiiji Fujiwara, Grant D Stewart, Benjamin Lamb, Krishna Narahari, Alan McNeill, Alexandra Colquhoun, John McGrath, Steve Bromage, Ravi Barod, Veeru Kasivisvanathan, Tobias Klatte, Joana Ff Simoes, Tom Ef Abbott, Sadi Abukhalaf, Michel Adamina, Adesoji O Ademuyiwa, Arnav Agarwal, Murat Akkulak, Ehab Alameer, Derek Alderson, Felix Alakaloko, Markus Albertsmeiers, Osaid Alser, Muhammad Alshaar, Sattar Alshryda, Alexis P Arnaud, Knut Magne Augestad, Faris Ayasra, José Azevedo, Brittany K Bankhead-Kendall, Emma Barlow, David Beard, Ruth A Benson, Ruth Blanco-Colino, Amanpreet Brar, Ana Minaya-Bravo, Kerry A Breen, Chris Bretherton, Igor Lima Buarque, Joshua Burke, Edward J Caruana, Mohammad Chaar, Sohini Chakrabortee, Peter Christensen, Daniel Cox, Moises Cukier, Miguel F Cunha, Giana H Davidson, Anant Desai, Salomone Di Saverio, Thomas M Drake, John G Edwards, Muhammed Elhadi, Sameh Emile, Shebani Farik, Marco Fiore, J Edward Fitzgerald, Samuel Ford, Tatiana Garmanova, Gaetano Gallo, Dhruv Ghosh, Gustavo Mendonça Ataíde Gomes, Gustavo Grecinos, Ewen A Griffiths, Madalegna GrÜndl, Constantine Halkias, Ewen M Harrison, Intisar Hisham, Peter J Hutchinson, Shelley Hwang, Arda Isik, Michael D Jenkinson, Pascal Jonker, Haytham Ma Kaafarani, Debby Keller, Angelos Kolias, Schelto Kruijff, Ismail Lawani, Hans Lederhuber, Sezai Leventoglu, Andrey Litvin, Andrew Loehrer, Markus W Löffler, Maria Aguilera Lorena, Maria Marta Modolo, Piotr Major, Janet Martin, Hassan N Mashbari, Dennis Mazingi, Symeon Metallidis, Ana Minaya-Bravo, Helen M Mohan, Rachel Moore, David Moszkowicz, Susan Moug, Joshua S Ng-Kamstra, Mayaba Maimbo, Ionut Negoi, Milagros Niquen, Faustin Ntirenganya, Maricarmen Olivos, Kacimi Oussama, Oumaima Outani, Marie Dione Parreno-Sacdalanm, Francesco Pata, Carlos Jose Perez Rivera, Thomas D Pinkney, Willemijn van der Plas, Peter Pockney, Ahmad Qureshi, Dejan Radenkovic, Antonio Ramos-De la Medina, Keith Roberts, April C Roslani, Martin Rutegård, Juan José Segura-Sampedro, Irène Santos, Sohei Satoi, Raza Sayyed, Andrew Schache, Andreas A Schnitzbauer, Justina O Seyi-Olajide, Neil Sharma, Richard Shaw, Sebastian Shu, Kjetil Soreide, Antonino Spinelli, Grant D Stewart, Malin Sund, Sudha Sundar, Stephen Tabiri, Philip Townend, Georgios Tsoulfas, Gabrielle H van Ramshorst, Raghavan Vidya, Dale Vimalachandran, Oliver J Warren, Duane Wedderburn, Naomi Wright, C Allemand, L Boccalatte, M Figari, M Lamm, J Larrañaga, C Marchitelli, F Noll, D Odetto, M Perrotta, J Saadi, L Zamora, C Alurralde, E L Caram, D Eskinazi, J P Mendoza, M Usandivaras, R Badra, A Esteban, J S García, P M García, J I 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Lewis-Lloyd, O Oyende, J Reilly, D Worku, P Cool, G Cribb, K Shepherd, C Bisset, S Moug, N Elson, G Faulkner, P Saleh, C Underwood, G Brixton, L Findlay, T Klatte, A Majkowska, J Manson, R Potter, A Bhalla, Z Chia, P Daliya, A Goyal, E Grimley, A Hamad, A Kumar, F L Malcolm, E Theophilidou, J Bowden, N Campain, I Daniels, C Evans, G Fowler, J John, L Massey, F McDermott, J McGrath, A McLennan, M Ng, J Pascoe, N Rajaretnam, S Bulathsinhala, B Davidson, G Fusai, C Hidalgo Salinas, N Machairas, T Pissanou, J M Pollok, D A Raptis, F Soggiu, H Tzerbinis, S E Xyda, A Beamish, E Davies, R Foulkes, D Magowan, H Nassa, R Ooi, C Price, L Smith, F Solari, A Tang, G Williams, Y Al-Tamimi, A Bacon, N Beasley, D Chew, M Crank, N Ilenkovan, M Macdonald, B Narice, O Rominiyi, A Thompson, I Varley, T Drake, E Harrison, G Linder, J Mayes, R McGregor, R Skipworth, V Zamvar, E Davies, P Hawkin, T Raymond, O Ryska, R Baron, D Dunne, S Gahunia, C Halloran, N Howes, R McKinney, F McNicol, J Russ, P Szatmary, J R Tan, A Thomas, P Whelan, A Anzak, A Banerjee, O Fuwa, F Hughes, J D Jayasinghe, C Knowles, H Kocher, I Leal Silva, F S Ledesma, A Minicozzi, L Navaratne, R Rahman, R Ramamoorthy, C Sohrabi, M Thaha, B Thakur, M Venn, V Yip, R Baumber, J Parry, S Evans, L Jeys, G Morris, M Parry, J Stevenson, N Ahmadi, G Aresu, Z M Barrett-Brown, A S Coonar, H Durio Yates, D Gearon, J Hogan, M King, A Peryt, I S Pradeep, C Smith, M Adishesh, R Atherton, K Baxter, M Brocklehurst, M Chaudhury, N Krishnamohan, J McAleer, G Owens, E Parkin, P Patkar, I Phang, A Aladeojebi, M Ali, B Barmayehvar, A Gaunt, M Gowda, E Halliday, M Kitchen, F Mansour, M Thomas, D Zakai, N Abbassi-Ghadi, H Assalaarachchi, A Currie, M Flavin, A Frampton, M Hague, C Hammer, J Hopper, J Horsnell, S Humphries, A Kamocka, T K Madhuri, S Preston, P Singh, J Stebbing, A Tailor, D Walker, F Aljanadi, M Jones, P Mhandu, C O'Donnell, R Turkington, Z Al-Ishaq, S Bhasin, A S Bodla, A Burahee, A Crichton, R Fossett, N Pigadas, S Pickford, E Rahman, D Snee, R Vidya, N Yassin, F Colombo, D Fountain, M T Hasan, K Karabatsou, R Laurente, O Pathmanaban, A Al-Mukhtar, S Brown, J Edwards, A Giblin, C Kelty, M Lee, G Lye, T Newman, A Sharkey, C Steele, N Sureshkumar Shah, E Whitehall, R Athwal, A Baker, L Jones, C Konstantinou, S Ramcharan, S Singh, J Vatish, R Wilkin, M Ethunandan, G K Sekhon, H Shields, R Singh, F Wensley, S Lawday, A Lyons, T Abbott, S Anwar, K Ghufoor, C Sohrabi, E Chung, R Hagger, A Hainsworth, A Karim, H Owen, A Ramwell, K Williams, C Baker, A Davies, J Gossage, M Kelly, W Knight, J Hall, G Harris, G James, C Kang, D J Lin, A D Rajgor, T Royle, R Scurrah, B Steel, L J Watson, D Choi, R Hutchison, A Jain, V Luoma, H Marcus, R May, A Menon, B Pramodana, L Webber, I A Aneke, P Asaad, B Brown, J Collis, S Duff, A Khan, F Moura, B Wadham, H Warburton, T Elmoslemany, M Jenkinson, C Millward, R Zakaria, S Mccluney, C Parmar, S Shah, J Allison, M S Babar, B Collard, S Goodrum, K Lau, A Patel, R Scott, E Thomas, H Whitmore, D Balasubramaniam, B Jayasankar, S Kapoor, A Ramachandran, A Elhamshary, Smb Imam, K Kapriniotis, V Kasivisvanathan, J Lindsay, S Rakhshani-Moghadam, N Beech, M Chand, L Green, N Kalavrezos, H Kiconco, R McEwen, C Schilling, D Sinha, J Pereca, J Singh, S Chopra, D Egbeare, R Thomas, T Combellack, Sef Jones, M Kornaszewska, M Mohammed, A Sharma, G Tahhan, V Valtzoglou, J Williams, P Eskander, K Gash, L Gourbault, M Hanna, T Maccabe, C Newton, J Olivier, S Rozwadowski, E Teh, D West, H Al-Omishy, M Baig, H Bates, G Di Taranto, K Dickson, N Dunne, C Gill, D Howe, D Jeevan, A Khajuria, K Martin-Ucar AMcEvoy, P Naredla, V Ng, S Robertson, M Sait, D R Sarma, S Shanbhag, T Shortland, S Simmonds, J Skillman, N Tewari, G Walton, M A Akhtar, A Brunt, J McIntyre, K Milne, M M Rashid, A Sgro, K E Stewart, A Turnbull, M Aguilar Gonzalez, S Talukder, C Boyle, D Fernando, K Gallagher, A Laird, D Tham, M Bath, P Patki, C Sohrabi, C Tanabalan, T Arif, C Magee, T Nambirajan, S Powell, R Vinayagam, I Flindall, A Hanson, V Mahendran, S Green, M Lim, L MacDonald, V Miu, L Onos, K Sheridan, R Young, F Alam, O Griffiths, C Houlden, R Jones, V S Kolli, A K Lala, S Leeson, R Peevor, Z Seymour, L Chen, E Henderson, A Loehrer, K Brown, D Fleming, A Haynes, C Heron, C Hill, H Kay, E Leede, K McElhinney, K Olson, E C Osterberg, C Riley, P Srikanth, M Thornhill, D Blazer, G DiLalla, E S Hwang, W Lee, M Lidsky, J Plichta, L Rosenberger, R Scheri, K Shah, K Turnage, J Visgauss, S Zani, J Farma, J Clark, D Kwon, E Etchill, H E Gabre-Kidan AJenny, A Kent, M Ladd, C Long, H Malapati, A Margalit, S Rapaport, J Rose, K Stevens, L Tsai, D Vervoort, P Yesantharao, A Dehal, D Klaristenfeld, K Huynh, L Brown, I Ganly, J Mullinax, N Gusani, J Hazelton, J Maines, J S Oh, A Ssentongo, P Ssentongo, M Azam, A Choudhry, W Marx, J Fleming, A Fuson, J Gigliotti, A Ovaitt, Y Ying, M K Abel, V Andaya, K Bigay, M A Boeck, L Chen, H Chern, C Corvera, I El-Sayed, A Glencer, P Ha, Bcs Hamilton, C Heaton, K Hirose, D M Jablons, K Kirkwood, L Z Kornblith, J R Kratz, R Lee, P N Miller, E Nakakura, B Nunez-Garcia, R O'Donnell, D Ozgediz, P Park, B Robinson, A Sarin, B Sheu, M Varma, K Wai, R Wustrack, M J Xu, D Beswick, J Goddard, J Manor, J Song, T Fullmer, C Gaskill, N Gross, K Kiong, C L Roland, S N Zafar, M Abdallah, A Abouassi, M Almasri, G Kulkarni, H Marwan, M Mehdi, S Aoun, V S Ban, H H Batjer, J Caruso, D Abbott, A Acher, T Aiken, J Barrett, E Foley, P Schwartz, S N Zafar, A Hawkins, A Maiga, J Laufer, S Scasso
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Aged, 80 and over ,Male ,Critical Care ,SARS-CoV-2 ,International Cooperation ,COVID-19 ,Middle Aged ,Cohort Studies ,Logistic Models ,Postoperative Complications ,Elective Surgical Procedures ,Neoplasms ,Outcome Assessment, Health Care ,Humans ,Female ,Epidemics ,Aged - Abstract
PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks.
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- 2021
10. Pelvic cross-sectional area at the level of the levator ani and prolapse
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John O L DeLancey, Anne G. Sammarco, Christopher X. Hong, Emily K. Kobernik, David Sheyn, and Carolyn W. Swenson
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medicine.medical_specialty ,Urology ,030232 urology & nephrology ,Pilot Projects ,Logistic regression ,Pelvic Organ Prolapse ,Article ,Obturator Internus Muscle ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,Medicine ,Humans ,Interspinous diameter ,Measurement plane ,Pelvis ,030219 obstetrics & reproductive medicine ,Pelvic floor ,business.industry ,Obstetrics and Gynecology ,Pelvic Floor ,Magnetic Resonance Imaging ,Levator ani ,medicine.anatomical_structure ,Case-Control Studies ,Intraabdominal pressure ,Female ,business - Abstract
INTRODUCTION AND HYPOTHESIS: Intraabdominal pressure acts on the pelvic floor through an aperture surrounded by bony and muscular structures of the pelvis. A small pilot study showed the area of the anterior portion of this plane is larger in pelvic organ prolapse. We hypothesize that there is a relationship between prolapse and anterior (APA) and posterior (PPA) pelvic cross-sectional area in a larger, more diverse population. STUDY DESIGN: MRIs from 30 prolapse subjects and 66 controls were analyzed in this case-control study. The measurement plane was tilted to approximate the level of the levator ani attachments. Three evaluators made measurements. Patient demographic characteristics were compared using Wilcoxon Rank-Sum and Fisher’s exact tests. A multivariable logistic regression model identified factors independently associated with prolapse. RESULTS: Controls were 3.7 years younger and had lower parity, but groups were similar in terms of race, height, and BMI. Cases had a larger APA (p
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- 2020
11. Documenting pessary offer prior to hysterectomy for management of pelvic organ prolapse
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Carolyn W. Swenson, Daniel M. Morgan, Neil Kamdar, and Anne G. Sammarco
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Pessary ,medicine.medical_specialty ,Urology ,Urinary system ,medicine.medical_treatment ,030232 urology & nephrology ,Conservative Treatment ,Hysterectomy ,Logistic regression ,Pelvic Organ Prolapse ,Article ,Colporrhaphy ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Preoperative Care ,Humans ,Medicine ,Medical history ,Aged ,Retrospective Studies ,Pelvic organ ,030219 obstetrics & reproductive medicine ,business.industry ,General surgery ,Obstetrics and Gynecology ,Middle Aged ,Pessaries ,Quality Improvement ,Case-Control Studies ,Concomitant ,Urinary Tract Infections ,Female ,business - Abstract
OBJECTIVES: To: 1) determine the proportion of hysterectomy cases with documentation of pessary counseling prior to prolapse surgery, and 2) identify variables associated with women offered a pessary. STUDY DESIGN: The Michigan Surgical Quality Collaborative (MSQC) is a hysterectomy improvement initiative. Hysterectomies from 2013-2015 in which prolapse was the principal diagnosis were included. "Pessary offer” was defined as documentation showing the patient declined, could not tolerate, or failed a pessary trial. Bivariate analyses were used to compare demographics, medical history, surgical route, concomitant procedures (colpopexy or colporrhaphy), as well as intra- and postoperative complications between women with and without pessary offer. Hierarchical logistic regression was used to determine factors independently associated with pessary offer. Risk-adjusted pessary offer rates by hospital were calculated. RESULTS: The adjusted rate of pessary offer was 25.2%, ranging from 3-76% per hospital. Bivariate comparisons showed differences between women with and without pessary offer in age, tobacco use, prior pelvic surgery, insurance status, surgical approach, secondary indication for surgery, concomitant prolapse procedure, teaching hospital status, and hospital bed size. In logistic regression, odds of pessary offer increased with age >55 (OR 1.45, 95% CI 1.12-1.88, p=.006), Medicare insurance (OR 1.65, 95% CI 1.30-2.10, p
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- 2018
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12. 08: The effect of age on pelvic diamond area in women with and without prolapse
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Cedric K. Olivera, Tessa E. Krantz, John O.L. DeLancey, David Sheyn, Antonio Antunes Rodrigues, Mariana Masteling, Anne G. Sammarco, and Emily K. Kobernik
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business.industry ,engineering ,Obstetrics and Gynecology ,Diamond ,Medicine ,Dentistry ,engineering.material ,business - Published
- 2019
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13. 21 Geometric analysis of the urethral-vaginal interface in women with and without stress urinary incontinence
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Anne G. Sammarco, David Sheyn, John O.L. DeLancey, and C.X. Hong
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Stress (mechanics) ,medicine.medical_specialty ,Geometric analysis ,business.industry ,Interface (computing) ,medicine ,Urology ,Obstetrics and Gynecology ,Urinary incontinence ,medicine.symptom ,business - Published
- 2021
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14. First Report of Bud Rot of Canary Island Date Palm Caused by Phytophthora palmivora in Italy
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Antonella Pane, C. Allatta, Santa Olga Cacciola, G. Sammarco, A PANE, C ALLATTA, G SAMMARCO, and CACCIOLA SO
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biology ,Phoenix canariensis ,Zoospore ,Sporangium ,Phytophthora palmivora ,Botany ,Ornamental plant ,Plant Science ,Phytophthora ,Palm ,biology.organism_classification ,Agronomy and Crop Science ,Petiole (botany) - Abstract
Canary Island date palm (Phoenix canariensis hort. ex Chabaud) is planted as an ornamental in Mediterranean climatic regions of the world. From 2004 to 2006, withering of the spear leaf was observed on screenhouse-grown potted plants of this palm in Sicily (Italy). The first symptom was a dark brown rot that extended from the petiole base of the spear to the adjacent youngest leaves and killed the bud. Dissection of plants revealed a foul-smelling internal rot. After the bud died, external older leaves remained green for months. As much as 10% of plants in a single nursery were affected. A Phytophthora species was consistently isolated from symptomatic plants on BNPRAH selective medium (4). Single zoospore isolates were obtained from the colonies. The species isolated was identified as Phytophthora palmivora (E. J. Butler) E. J. Butler on the basis of morphological and cultural characteristics (3). On V8 juice agar, the isolates produced elliptical to ovoid, papillate sporangia (33 to 77 × 22 to 38 μm) with a mean length/breadth ratio of 1.8. Sporangia were caducous with a short pedicel (mean pedicel length = 5 μm) and had a conspicuous basal plug. All isolates were heterothallic and produced amphigynous antheridia, oogonia, and oospores when paired with reference isolates of P. nicotianae and P. palmivora of the A2 mating type. The oogonium wall was smooth. Identification was confirmed by electrophoresis of mycelial proteins in polyacrylamide slab gels (1). The electrophoretic patterns of total mycelial proteins and four isozymes (alkaline phosphatase, esterase, glucose-6-phosphate dehydrogenase, and malate dehydrogenase of the isolates) from Phoenix canariensis were identical to those of P. palmivora reference isolates, including four Italian ones, two from pittosporum and olive, respectively, and two (IMI 390579 and 390580) from Grevillea spp. Phoenix canariensis isolates were clearly distinct from those of other heterothallic papillate species including P. capsici, P. citrophthora, P. katsurae, P. nicotianae, and P. tropicalis. Pathogenicity of one isolate from Phoenix canariensis (IMI 395345) was tested on 10 2-year-old potted Canary Island date palm plants. An aqueous 105 zoospores per ml suspension (200 μl) was pipetted onto unwounded petiole bases of the three youngest central leaves of each plant. Sterile water was pipetted onto 10 control plants. All plants were incubated in 100% humidity at 24°C for 48 h and maintained in a greenhouse at 20 to 28°C. Within 3 weeks after inoculation, inoculated plants developed symptoms identical to those observed on plants with natural infections. Control plants remained healthy. P. palmivora was reisolated from symptomatic plants. Phytophthora bud rot is a common palm disease worldwide and Phoenix canariensis is reported as a host (2). To our knowledge, this is the first report of Phytophthora bud rot on Phoenix canariensis in Italy. References: (1) S. O. Cacciola et al. EPPO Bull. 20:47, 1990. (2) M. L. Elliot et al., eds. Compendium of Ornamental Palm Diseases and Disorders. The American Phytopathological Society, St. Paul, MN, 2004. (3) D. C. Erwin and O. K. Ribeiro. Phytophthora Diseases Worldwide. The American Phytopathological Society, St. Paul, MN, 1996. (4) H. Masago et al. Phytopathology, 67:425, 1977.
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- 2019
15. 40: Pelvic cross sectional area at the level of the levator ani is associated with prolapse
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Emily K. Kobernik, Carolyn W. Swenson, David Sheyn, C.X. Hong, Anne G. Sammarco, and John O.L. DeLancey
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Gynecology ,medicine.medical_specialty ,Levator ani ,business.industry ,medicine ,Obstetrics and Gynecology ,business - Published
- 2020
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16. A novel measurement of pelvic floor cross-sectional area in older and younger women with and without prolapse
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Mariana Masteling, Antonio Antunes Rodrigues, Tessa E. Krantz, David Sheyn, John O.L. DeLancey, Cedric K. Olivera, Emily K. Kobernik, and Anne G. Sammarco
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Adult ,medicine.medical_specialty ,Aging ,Adolescent ,Pilot Projects ,Pelvic Organ Prolapse ,Article ,Obturator Internus Muscle ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Imaging, Three-Dimensional ,medicine ,Humans ,030212 general & internal medicine ,Stage (cooking) ,Pelvis ,030219 obstetrics & reproductive medicine ,Pelvic floor ,medicine.diagnostic_test ,business.industry ,Obstetrics and Gynecology ,Magnetic resonance imaging ,Pelvic Floor ,Middle Aged ,Magnetic Resonance Imaging ,Surgery ,Exact test ,Levator ani ,medicine.anatomical_structure ,Case-Control Studies ,Female ,business ,Body mass index - Abstract
Background An increase in size of the aperture of the pelvis that must be spanned by pelvic floor support structures translates to an increase in the force on these structures. Prior studies have measured the bony dimensions of the pelvis, but the effect of changes in muscle bulk that may affect the size of this area are unknown. Objectives To develop a technique to evaluate the aperture size in the anterior pelvis at the level of the levator ani muscle attachments, and identify age-related changes in women with and without prolapse. Study Design This was a technique development and pilot case-control study evaluating pelvic magnetic resonance imaging (MRI) from 30 primiparous women from the Michigan Pelvic Floor Research Group MRI Data Base: 10 younger women with normal support, 10 older women with, and 10 older menopausal women without prolapse. Anterior pelvic area measurements were made in a plane that included the bilateral ischial spines and the inferior pubic point, approximating the level of the arcus tendineus fascia pelvis. Measurements of the anterior pelvic area, obturator internus muscles, and interspinous diameter were made by five independent raters from the Society of Gynecologic Surgeons Pelvic Anatomy Group that focused on developing pelvic imaging techniques, and evaluating inter-rater reliability. Demographic characteristics were compared across groups of interest using Wilcoxon rank sum test, Chi-square, or Fisher’s exact test where appropriate. Multiple linear regression models were created to identify independent predictors of anterior pelvic area. Results Per the study design, groups differed in age and prolapse stage. There were no differences in race, height, body mass index, gravidity or parity. Patients with prolapse had a significantly longer interspinous diameter, and more major (>50% of the muscle) levator ani defects when compared to both older and younger women without prolapse. Inter-rater reliability was high for all measurements (ICC=.96). The anterior pelvic area (cm2) was significantly larger in older women with prolapse compared to older (60±5.1 vs. 53±4.9, p=.004) and younger (60±5.1 vs. 52±4.6, p=.001) women with normal support. The young and older normal support women did not differ in anterior pelvic area (52±4.6 vs 53±4.9, p= 0.99). After adjusting for race and BMI, increased anterior pelvic area was significantly associated with the following: 1) being an older woman with prolapse (β = 6.61cm2, p=.004), and 2) IS distance (β = 4.52cm2, p=.004). Conclusions Older women with prolapse had the largest anterior area, suggesting that the anterior pelvic area is a novel measure to consider when evaluating women with prolapse. Interspinous diameter, and being an older woman with prolapse, was associated with a larger anterior pelvic area. This suggests that reduced obturator internus muscle size with age may not be the primary factor in determining anterior pelvic area, but pelvic dimensions such as interspinous diameter could play a role. The measurements were highly repeatable. The high ICC indicates that all raters were able to successfully learn the imaging software and perform measurements with high reproducibility.
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- 2019
17. Levator bowl volume during straining and its relationship to other levator measures
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Luyun Chen, Anne G. Sammarco, Lahari Nandikanti, John O.L. DeLancey, and James A. Ashton-Miller
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Adult ,Urology ,030232 urology & nephrology ,Anal Canal ,3d model ,Pelvic Organ Prolapse ,Article ,Levator hiatus ,03 medical and health sciences ,0302 clinical medicine ,Imaging, Three-Dimensional ,Urogenital hiatus ,Medicine ,Humans ,Two sample ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Anatomy ,Organ Size ,Pelvic Floor ,Middle Aged ,Control subjects ,Magnetic Resonance Imaging ,Sagittal plane ,medicine.anatomical_structure ,Levator ani ,Case-Control Studies ,Female ,business ,human activities ,Volume (compression) - Abstract
INTRODUCTION AND HYPOTHESIS: This study aimed to: 1) measure levator ani bowl volume at rest and while straining, 2) compare women with and without prolapse (controls), and 3) assess the ability of measures of mid-sagittal bowl area, levator hiatus (LH), and urogenital hiatus (UGH) to predict bowl volume. METHODS: Forty MRI scans previously acquired in case-control prolapse studies including 20 women with prolapse and 20 women without prolapse, of similar age and parity, were selected. 3D models of rest and strain bowl volumes were made using sagittal scans and 3D Slicer®. Mid-sagittal bowl area, UGH, and LH were measured with ImageJ. Data were analyzed using two sample t-tests, effect sizes, and Pearson’s correlation coefficients at the 0.05 significance level. RESULTS: Data were acquired in a total of 40 total women. Levator bowl volume at strain had a correlation coefficient of 0.5 with bowl volume at rest. During straining, prolapse subjects had a 53% larger bowl volume than control subjects (254 ± 86 cm(3) vs. 166 ± 44 cm(3), p0.75). The strongest correlation with straining bowl volume was straining bowl area (r=0.86), followed by LH strain (r=0.80), then UGH strain (r=0.76). CONCLUSIONS: Straining levator bowl volume is substantially different than measures made at rest, with only a quarter of straining values explained by resting measurements. The bowl area at strain is the best 2D measurement estimating bowl volume and explains 74% of straining bowl volume.
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- 2019
18. The Latzko: A high-value, versatile vesicovaginal fistula repair
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Caroline, Kieserman-Shmokler, Anne G, Sammarco, Emily M, English, Carolyn W, Swenson, and John O, DeLancey
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Gynecologic Surgical Procedures ,Vesicovaginal Fistula ,Humans ,Urologic Surgical Procedures ,Female ,Article - Abstract
The Latzko transvaginal vesicovaginal fistula repair is a highly effective treatment for even complex fistulae. Our video demonstrates the Latzko technique and its application in a variety of circumstances including fistula management concurrent with treatment of uterovaginal prolapse, following complex urologic surgery, and in the postpartum setting after urologic injury. The technique of the procedure varies only slightly in these diverse conditions. The basic steps begin with hydro-dissecting the epithelium from the underlying fascia surrounding the fistula tract, followed by denuding the epithelium within a circumscribing incision around the fistula (Figure 1A). The fistula is then closed with a purse-string suture placed just outside the epithelialized tract. Next, several layers of imbricating sutures are placed to close the defect (Figure 1B). Finally, the vaginal epithelium is closed (Figure 1C).
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- 2019
19. S1pr2 is a key mediator of endoplasmic reticulum stress in NAFLD/ NASH pathogenesis
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A. Lleo, A. Aghemo, G. Sammarco, S. Vetrano, G. Rizzo, Matteo Donadon, L. Petti, S. Restelli, P. Corsetto, V. Arena, A.M. Rizzo, R. Ceriani, and G. Carpino
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Pathogenesis ,Mediator ,Hepatology ,Endoplasmic reticulum ,Key (cryptography) ,Biology ,S1PR2 ,Cell biology - Published
- 2020
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20. Lower Urinary Tract Symptoms in a Chronic Pelvic Pain Population
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Anne G. Sammarco, Mitchell B. Berger, Sara R. Till, Emily K. Kobernik, and Hope K. Haefner
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Adult ,medicine.medical_specialty ,Urology ,Population ,030232 urology & nephrology ,Pelvic Pain ,Severity of Illness Index ,03 medical and health sciences ,0302 clinical medicine ,Lower Urinary Tract Symptoms ,Lower urinary tract symptoms ,Interquartile range ,Internal medicine ,Surveys and Questionnaires ,medicine ,Prevalence ,Humans ,education ,Depression (differential diagnoses) ,Pain Measurement ,Retrospective Studies ,education.field_of_study ,030219 obstetrics & reproductive medicine ,business.industry ,Pelvic pain ,Chronic pain ,Obstetrics and Gynecology ,Interstitial cystitis ,Middle Aged ,medicine.disease ,Neuropathic pain ,Surgery ,Female ,medicine.symptom ,Chronic Pain ,business - Abstract
OBJECTIVES This study aimed to characterize the prevalence of lower urinary tract symptoms in a chronic pain population. METHODS In this observational cohort study, patients referred to a female pelvic pain clinic completed several validated questionnaires assessing bladder symptoms, central sensitization, pain symptoms, depression, anxiety, and neuropathic pain. Patients diagnosed as having interstitial cystitis were excluded. Patient demographic characteristics and survey responses were compared across American Urological Association Symptom Index (AUA-SI) severity categories. Multivariable logistic regression was performed to identify independent predictors of moderate-to-severe AUA-SI scores. RESULTS A total of 177 patients were included in the analysis. American Urological Association Symptom Index data showed that 48.8% of patients had mild, 31.2% had moderate, and 20.0% had severe symptoms. Patients reporting moderate or severe AUA-SI scores had higher mean Central Sensitization Inventory (CSI) scores (46.7 ± 16.0 vs 32.9 ± 13.8, P < 0.0001), McGill scores (median, 25 [interquartile range, 16-38] vs 13 [5-27]; P = 0.0003), Patient-Reported Outcomes Measurement Information System depression T-scores (median, 53.9 [interquartile range, 46.2-61.6] vs 51.2 [37.1-55.3]; P = 0.009), Pelvic Pain and Urgency/Frequency Symptoms Scale scores (18.4 ± 6.2 vs 12.5 ± 5.4, P < 0.0001), and Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs scores (median, 10.5 [interquartile range, 3.0-16.5] vs 6.0 [1.0-12.0]; P = 0.02). The odds of moderate-to-severe AUA-SI symptoms were higher with a positive PUF and CSI score and were lower with a diagnosis of vestibular pain. CONCLUSIONS There is a high prevalence of lower urinary tract symptoms among patients with chronic pelvic pain. Vestibulodynia was associated with lower odds of bladder symptoms. High PUF and CSI scores were significantly associated with moderate-to-severe bladder symptoms.
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- 2019
21. Traumatic Dislocation of Three Major Joints in the Lower Limb: Management and Outcome
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L. Scialpi, Giuseppe Maccagnano, Angela Notarnicola, B. Scialpi, and G. Sammarco
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medicine.medical_specialty ,Physical medicine and rehabilitation ,business.industry ,medicine ,Orthopedics and Sports Medicine ,Traumatic dislocation ,business ,Outcome (game theory) ,Lower limb - Published
- 2020
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22. Rate of Pelvic Organ Prolapse Surgery Among Privately Insured Women in the United States, 2010–2013
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Daniel M. Morgan, Neil Kamdar, John O.L. DeLancey, Emily K. Kobernik, Brahmajee K. Nallamothu, Carolyn W. Swenson, and Anne G. Sammarco
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Adult ,medicine.medical_specialty ,030232 urology & nephrology ,Article ,Pelvic Organ Prolapse ,Food and drug administration ,03 medical and health sciences ,Outpatient procedures ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Medicine ,Humans ,Practice Patterns, Physicians' ,Aged ,Retrospective Studies ,Aged, 80 and over ,Pelvic organ ,030219 obstetrics & reproductive medicine ,Insurance, Health ,business.industry ,United States Food and Drug Administration ,Prolapse surgery ,Obstetrics and Gynecology ,Retrospective cohort study ,Inpatient utilization ,Middle Aged ,Surgical Mesh ,United States ,Surgical mesh ,Emergency medicine ,Health care cost ,Linear Models ,Female ,business ,Procedures and Techniques Utilization - Abstract
Objective To analyze utilization of, and payments for, pelvic organ prolapse procedures after the 2011 U.S. Food and Drug Administration (FDA) communication regarding transvaginal mesh. Methods This is a retrospective cohort study examining private claims from three insurance providers for inpatient and outpatient prolapse procedures from 2010 to 2013 in the Health Care Cost Institute. Primary outcomes were the change in utilization of prolapse procedures, with and without mesh, before and after the July 2011 FDA communication. Secondary outcomes were the changes in payments and reimbursements for these procedures. Utilization rates and payments were compared using generalized linear models and interrupted time-series analysis. Results Utilization of prolapse procedures decreased from 12.3 to 9.7 per 10,000 woman-years (P=.027) with a decrease of 30.7% (3.9 in 2010 to 2.7 in 2013, P=.05) in number of mesh procedures and 16.6% (8.4 in 2010 to 7.0 in 2013, P=.011) for nonmesh procedures. Quarterly utilization of mesh procedures was increasing before the FDA communication and then significantly declined after its release (slope=0.024 vs -0.025, P=.002). Nonmesh procedures, however, were already slightly decreasing before July 2011 and continued to decline at a more rapid pace after that time, although not significantly (slope=-0.004 vs -0.022, P=.47). Inpatient utilization decreased 52.2% (P=.002), whereas outpatient utilization increased 18.5% (P=.132). Payments for individual inpatient procedures, with and without mesh, increased by 12.0% ($8,315 in 2010 to $9,315 in 2013, P=.001) and 15.6% ($7,826 in 2010 to $9,048 in 2013, P=.005), respectively, whereas those for outpatient procedures increased by 41% ($4,961 in 2010 to $6,981 in 2013, P=.006) and 30% ($3,955 in 2010 to $5,149 in 2013, P=.004), respectively. Conclusion Use of prolapse surgery declined during the study period. After the 2011 FDA communication regarding transvaginal mesh, there was a significant decrease in the utilization of procedures with mesh but not for those without mesh. A shift toward outpatient surgeries was observed, and payments for both individual inpatient and outpatient cases increased.
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- 2018
23. Levator ani defect severity and its association with enlarged hiatus size, levator bowl depth, and prolapse size
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Anne G. Sammarco, Emily K. Kobernik, Lahari Nandikanti, and John O.L. DeLancey
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030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,Obstetrics and Gynecology ,Magnetic resonance imaging ,Organ Size ,Anatomy ,Pelvic Floor ,Hiatus ,Magnetic Resonance Imaging ,Pelvic Organ Prolapse ,03 medical and health sciences ,0302 clinical medicine ,Levator ani ,Medicine ,Humans ,Female ,030212 general & internal medicine ,business - Published
- 2017
24. Nationwide trends in the utilization of and payments for hysterectomy in the United States among commercially insured women
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Anne G. Sammarco, Brahmajee K. Nallamothu, Daniel M. Morgan, Neil Kamdar, Emily K. Kobernik, and Carolyn W. Swenson
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Adult ,medicine.medical_specialty ,Uterine fibroids ,medicine.medical_treatment ,Outpatient surgery ,Endometriosis ,Datasets as Topic ,Hysterectomy ,Article ,Reimbursement Mechanisms ,03 medical and health sciences ,0302 clinical medicine ,Laparotomy ,Medicine ,Humans ,030212 general & internal medicine ,Laparoscopy ,Reimbursement ,Aged ,030219 obstetrics & reproductive medicine ,Insurance, Health ,medicine.diagnostic_test ,business.industry ,General surgery ,Obstetrics and Gynecology ,General Medicine ,Ambulatory Surgical Procedure ,Middle Aged ,medicine.disease ,United States ,Hospitalization ,Ambulatory Surgical Procedures ,Concomitant ,Female ,business - Abstract
Background Laparotomy followed by inpatient hospitalization has traditionally been the most common surgical care for hysterectomy. The financial implications of the increased use of laparoscopy and outpatient hysterectomy are unknown. Objectives The objective of the study was to quantify the increasing use of laparoscopy and outpatient hysterectomy and to describe the financial implications among women with commercially based insurance in the United States. Study Design Hysterectomies between 2010 and 2013 were identified in the Health Care Cost Institute, a national data set with inpatient and outpatient private insurance claims for more than 25 million women. Surgical approach was categorized with procedure codes as abdominal, laparoscopic, laparoscopic assisted vaginal, or vaginal. Payments were adjusted to 2013 US dollars to account for change because of inflation. Results Between 2010 and 2013, there were 386,226 women who underwent hysterectomy. The rate of utilization decreased 12.4%, from 39.9 to 35.0 hysterectomies per 10,000 women. The largest absolute decreases were observed among women younger than 55 years and among those with uterine fibroids, abnormal uterine bleeding, and endometriosis. The proportion of laparoscopic hysterectomies increased from 26.1% to 43.4%, with concomitant decreases in abdominal (38.6% to 28.3%), laparoscopic assisted vaginal (20.2 to 16.7%), and vaginal (15.1% to 11.5%) hysterectomies. There was also a shift from inpatient to outpatient surgery. In 2010, the inpatient and outpatient rates of hysterectomy were 26.6 and 13.3 per 10,000 women, respectively. By 2013, the rates were 15.4 and 19.6 per 10,000 women. In each year of analysis, the average reimbursement for outpatient procedures was 44-46% less than for similar inpatient procedures. Offsetting the lower utilization of hysterectomy and lower reimbursement for outpatient surgery were increases in average inpatient and outpatient hysterectomy reimbursement of 19.4% and 19.8%, respectively. Total payments for hysterectomy decreased 6.3%, from $823.4 million to $771.3 million. Conclusion Between 2010 and 2013, laparoscopy emerged as the most common surgical approach for hysterectomy, and outpatient hysterectomy became more common than inpatient among women with commercially based insurance. While average reimbursement per case increased, overall payments for hysterectomy are decreasing because of decreased utilization and dramatic differences in how hysterectomy is performed.
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- 2017
25. The Latzko
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Emily M English, Caroline Kieserman-Shmokler, John O L DeLancey, Anne G. Sammarco, and Carolyn W. Swenson
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medicine.medical_specialty ,030219 obstetrics & reproductive medicine ,business.industry ,Fistula ,Obstetrics and Gynecology ,Fascia ,Uterovaginal prolapse ,medicine.disease ,Vesicovaginal fistula ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Suture (anatomy) ,medicine ,Effective treatment ,Urologic surgery ,030212 general & internal medicine ,Vaginal epithelium ,business - Abstract
The Latzko transvaginal vesicovaginal fistula repair is a highly effective treatment for even complex fistulae. Our video demonstrates the Latzko repair technique and its application in a variety of circumstances that include fistula management concurrent with treatment of uterovaginal prolapse, after complex urologic surgery, and in the postpartum setting after urologic injury. The technique of the procedure varies only slightly in these diverse conditions. The basic steps begin with hydro-dissecting the epithelium from the underlying fascia surrounding the fistula tract, followed by denuding the epithelium within a circumscribing incision around the fistula. The fistula is then closed with a purse-string suture placed just outside the epithelialized tract. Next, several layers of imbricating sutures are placed to close the defect. Finally, the vaginal epithelium is closed.
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- 2019
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26. Severe Labial Agglutination Release in a Postmenopausal Woman
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Sangeeta T. Mahajan, Rebecca L. James, David Sheyn, and Anne G. Sammarco
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medicine.medical_specialty ,business.industry ,media_common.quotation_subject ,medicine.disease ,Urination ,Introitus ,Surgery ,medicine.anatomical_structure ,Blunt dissection ,Uterine cancer ,Labia minora ,Dilator ,medicine ,Enlarged Uterus ,business ,Screening procedures ,media_common - Abstract
Labial agglutination occurs when the labia minora have become fused in the midline through either filmy or dense adhesions, forming a raphe. This condition is typically seen in pre-pubertal girls; however, there have been cases reported in the literature of labial agglutination in postmenopausal and reproductive aged women. Labial agglutination has been associated with local irritation and inflammation in the setting of a hypoestrogenic state. Topical treatment is usually recommended prior to manual separation. However, some postmenopausal women have been refractory to conservative management, and surgery may then be required. We present a case of a 79-year-old Caucasian gravida 3 para 3 who was referred for treatment refractory labial agglutination for 3 years. The patient’s complaints included a small trickle escaping from the introitus during urination and the sensation of little urinary control. The patient underwent an exam under anesthesia. Gentle blunt dissection with a lacrimal dilator easily separated the labia minora down the visible midline fusion line (raphe). Bimanual exam then revealed a 12-week-sized enlarged uterus confirmed on ultrasound to be an 8 × 8 × 7 cm irregular mass concerning for uterine cancer. Proceeding to an operative release of severe labial agglutination can relieve patient discomfort and frustration when estradiol therapy has failed. In addition to alleviating symptoms, releasing labial agglutination can also provide the gynecologist access to critical screening procedures such as cervical cytology or a bimanual exam, all of which could lead to a diagnosis or pre-cancerous or cancerous lesions.
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- 2014
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27. Are perioperative bundles associated with reduced postoperative morbidity in women undergoing benign hysterectomy? Retrospective cohort analysis of 16,286 cases in Michigan
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Neil Kamdar, John A. Harris, Sarah Evilsizer, D.A. Campbell, Anne G. Sammarco, Daniel M. Morgan, John O.L. DeLancey, Shitanshu Uppal, and Carolyn W. Swenson
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medicine.medical_specialty ,Michigan ,medicine.medical_treatment ,Operative Time ,Hysterectomy ,Patient Readmission ,Article ,Hemostatics ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,medicine ,Humans ,030212 general & internal medicine ,Antibiotic prophylaxis ,Prospective cohort study ,Aged ,Retrospective Studies ,030219 obstetrics & reproductive medicine ,business.industry ,General surgery ,Contraindications ,Obstetrics and Gynecology ,Retrospective cohort study ,General Medicine ,Perioperative ,Antibiotic Prophylaxis ,Surgery ,Quartile ,Female ,Laparoscopy ,Complication ,business ,Patient Care Bundles ,Cohort study - Abstract
Healthcare teams that frequently follow a bundle of evidence-based processes provide care with lower rates of morbidity. Few process bundles to improve surgical outcomes in hysterectomy have been identified.The purpose of this study was to investigate whether a bundle of 4 perioperative care processes is associated with fewer postoperative complications and readmissions for hysterectomies in the Michigan Surgical Quality Collaborative.A bundle of perioperative care process goals was developed retrospectively with 30-day peri- and postoperative outcome data from the Hysterectomy Initiative in Michigan Surgical Quality Collaborative. All benign hysterectomies that had been performed between January 2013 and January 2015 were included. Based on evidence of lower complication rates after benign hysterectomy, the following processes were considered to be the "bundle": use of guideline-appropriate preoperative antibiotics, a minimally invasive surgical approach, operative duration120 minutes, and avoidance of intraoperative hemostatic agent use. Each process was considered present or absent, and the number of processes was summed for a bundle score that ranged from 0-4. Cases with a score of zero were excluded. Outcomes measured were rates of complications (any and major) and hospital readmissions, all within 30 days of surgery. Postoperative events that were considered a "major complication" included acute renal failure, cardiac arrest that required cardiopulmonary resuscitation, central line infection, cerebral vascular accident, death, deep vein thrombosis, intestinal obstruction, myocardial infarction, pelvic abscess, pulmonary embolism, rectovaginal fistula, sepsis, surgical site infection (deep and organ-space), unplanned intubation, ureteral obstruction, and ureterovaginal and vesicovaginal fistula. The outcome "any complication" included all those events already described in addition to blood transfusion within 72 hours of surgery, urinary tract infection, and superficial surgical site infection. Outcomes were adjusted for patient demographics, surgical factors, and hospital-level clustering effects.There were 16,286 benign hysterectomies available for analysis. Among all hysterectomies that were reviewed, 33.6% met criteria for all bundle processes; however, there was wide variation in the rate among the 56 hospitals in the study sample with 9.1% of cases at the lowest quartile and 60.4% at the highest quartile of hospitals that met criteria for all bundle processes. Overall, the rate of any complication was 6.8% and of any major complication was 2.3%. The rate of hospital readmissions was 3.6%. After adjustment for confounders, in cases in which all bundle criterion were met compared with cases in which all bundle criterion were not met, the rate of any complications increased from 4.3-7.8% (P.001); major complications increased from 1.7-2.6% (P.001), and readmissions increased from 2.6-4.1% (P.001). After adjustment for confounders, hospitals with greater rates of meeting all 4 criteria were associated significantly with lower hospital-level rates of postoperative complications (P.001) and readmissions (P.001).This multiinstitutional evaluation reveals that reduced morbidity and readmission are associated with rates of bundle compliance. The proposed bundle is a surgical goal, which is not possible in every case, and there is significant variation in the proportion of cases meeting all 4 bundle processes in Michigan hospitals. Implementation of evidence-based process bundles at a healthcare system level are worthy of prospective study to determine whether improvements in patient outcomes are possible.
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- 2017
28. Interactions among pelvic organ protrusion, levator ani descent, and hiatal enlargement in women with and without prolapse
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John O.L. DeLancey, Lahari Nandikanti, Anne G. Sammarco, Emily K. Kobernik, Carolyn W. Swenson, Alexandra Jankowski, and Bing Xie
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medicine.medical_specialty ,Valsalva Maneuver ,Vaginal wall ,Pelvic Organ Prolapse ,Article ,Levator hiatus ,03 medical and health sciences ,0302 clinical medicine ,Urogenital hiatus ,medicine ,Humans ,030212 general & internal medicine ,Aged ,Pelvic organ ,030219 obstetrics & reproductive medicine ,medicine.diagnostic_test ,business.industry ,Obstetrics and Gynecology ,Magnetic resonance imaging ,Anatomy ,Organ Size ,Pelvic Floor ,Middle Aged ,Magnetic Resonance Imaging ,Surgery ,stomatognathic diseases ,medicine.anatomical_structure ,Levator ani ,Logistic Models ,Hymen ,Case-Control Studies ,Female ,business - Abstract
Background Pelvic organ prolapse has 2 components: (1) protrusion of the pelvic organs beyond the hymen; and (2) descent of the levator ani. The Pelvic Organ Prolapse Quantification system measures the first component, however, there remains no standard measurement protocol for the second mechanism. Objective We sought to test the hypotheses that: (1) difference in the protrusion area is greater than the area created by levator descent in prolapse patients compared with controls; and (2) prolapse is more strongly associated with levator hiatus compared to urogenital hiatus. Study Design Midsagittal magnetic resonance imaging scans from 30 controls, 30 anterior predominant, and 30 posterior predominant prolapse patients were assessed. Levator area was defined as the area above the levator ani and below the sacrococcygeal inferior pubic point line. Protrusion area was defined as the protruding vaginal walls below the levator area. The levator hiatus and urogenital hiatus were measured. Bivariate analysis and multiple comparisons were performed. Bivariate logistic regression was performed to assess prolapse as a function of levator hiatus, urogenital hiatus, levator area, and protrusion. Pearson correlation coefficients were calculated. Results The levator area for the anterior (34.0 ± 6.5 cm 2 ) and posterior (35.7 ± 8.0 cm 2 ) prolapse groups were larger during Valsalva compared to controls (20.9 ± 7.8 cm 2 , P 2 ) and posterior (14.4 ± 5.7 cm 2 ) prolapse groups were both larger compared to controls (5.0 ± 1.8 cm 2 , P P P 2 vs 9.4 ± 5.9 cm 2 , P P ≤ .001, for all comparisons). Conclusion In prolapse, the levator area increases more than the protrusion area and both the urogenital hiatus and levator hiatus are larger. The odds of prolapse for an increase in the urogenital hiatus are 3 times larger than for the levator hiatus, which leads us to reject both the original hypotheses.
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- 2016
29. Plexiform schwannoma: an unusual clitoral mass
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Paige V. Tracy, Noor M. Abualnadi, Mitchell B. Berger, Anne G. Sammarco, Elizabeth Andraska, and Hope K. Haefner
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Adult ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Clitoromegaly ,Schwannoma ,Clitoris ,Benign tumor ,03 medical and health sciences ,0302 clinical medicine ,Gynecologic Surgical Procedures ,Medicine ,Humans ,In patient ,Neurofibromatosis ,Peripheral Nerve Sheath ,Vulvar Neoplasms ,business.industry ,Obstetrics and Gynecology ,Partial Vulvectomy ,medicine.disease ,Surgery ,Plexiform Schwannoma ,030220 oncology & carcinogenesis ,Female ,medicine.symptom ,business ,Neurilemmoma - Abstract
Acquired clitoral enlargement is a rare condition resulting from a variety of etiologies, including tumors and excess androgens. Few cases of nonmalignant schwannoma, a benign tumor of the peripheral nerve sheath, have been reported in the literature as causes of clitoral enlargement in patients without known neurofibromatosis. These painless, slow-growing tumors rarely recur once excised. We present the initial investigation of a patient with a large clitoral schwannoma and subsequent treatment with partial vulvectomy. The workup, including advanced pelvic imaging for diagnosis and surgical planning, as well as removal of the clitoral tumor with preservation of functional tissue and restoration of normal vulvar anatomy despite a large excision, is demonstrated.
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- 2016
30. A pilot observational study on magnesium and calcium imbalance in elderly patients with acute aortic dissection
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Elena Dozio, Santi Trimarchi, M.M. Corsi Romanelli, Lorenza Tacchini, G. Sammarco, Massimiliano M. Marrocco-Trischitta, Elena Vianello, and Alessandra Barassi
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0301 basic medicine ,Aging ,medicine.medical_specialty ,Immunology ,Vasodilation ,Clinical nutrition ,Acute aortic dissection (AAD) ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine.artery ,Magnesium (Mg) ,Calcium (Ca) ,medicine ,Endothelial dysfunction ,Aortic dissection ,Aorta ,business.industry ,Research ,medicine.disease ,Pathophysiology ,Endothelial stem cell ,Ageing ,030104 developmental biology ,Endocrinology ,Cardiology ,business ,Homeostasis - Abstract
Background Magnesium (Mg) and calcium (Ca) are the principal essential elements involved in endothelial cell homeostasis. Extracellular changes in the levels of either alter endothelial contraction and dilatation. Consequently Mg and Ca imbalance is associated with a high risk of endothelial dysfunction, the main process observed during acute aortic dissection (AAD); in this clinical condition, which mainly affects elderly men, smooth muscle cell alterations lead to intimal tears, creating a false new lumen in the media of the aorta. AAD patients have a high risk of mortality as a result of late diagnosis because often it is not distinguished from other cardiovascular diseases. We investigated Mg and Ca total circulating levels and the associated pro-inflammatory mediators in elderly AAD patients, to gain further information on the pathophysiology of this disorder, with a view to suggesting newer and earlier potential biomarkers of AAD. Results Total circulating Mg and Ca levels were both lower in AAD patients than controls (p 0.05) The levels of both ICAM-1 and EN-1 were lower in AAD than in a control group (p
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- 2016
31. PD27-05 THE USE OF ONABOTULINUMTOXINA FOR TREATMENT OF OVERACTIVE BLADDER IN OLDER PATIENTS
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Adonis Hijaz, Anne G. Sammarco, Penny Benchek, Sangeeta T. Mahajan, Elizabeth Kate Ferry, Dhruti Patel, and Elias Kikano
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medicine.medical_specialty ,Overactive bladder ,Older patients ,business.industry ,Urology ,medicine ,medicine.disease ,business - Published
- 2015
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32. A VIRTUAL REALITY BASED TELELABORATORY FOR THE REMOTE LEARNING OF ROBOTICS
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Maria Letizia Corradini and G. Sammarco
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Engineering ,Multimedia ,Active learning (machine learning) ,business.industry ,Remote learning ,Robotics ,Virtual reality ,computer.software_genre ,Artificial intelligence ,MATLAB ,business ,computer ,Remote laboratory ,computer.programming_language ,Instructional simulation - Abstract
In the present work, a virtual reality system, used in the framework of a web-based educational tool, is presented. Such tool, called VRL , can be used as a support for active learning of robotics in a web-learning environment. VRL guarantees forms of flexible learning, and couples virtual reality experiments, obtained through the integration of Matlab and Shockwave technology, and remote lab experiments, in order to allow a preliminary verification of theoretical concepts without the risks of damaging the remote experimental device.
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- 2006
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33. Effect of Inter-Professional Labor Management Guidelines on Adverse Outcomes in an Academic Labor and Delivery Unit [21D]
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Natalie Tapaskar, Kimberly S. Gecsi, Anne G. Sammarco, and David Hackney
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Labor management ,Nursing ,Adverse outcomes ,business.industry ,Obstetrics and Gynecology ,Medicine ,business ,Unit (housing) - Published
- 2016
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34. Tobacco use as a risk factor for reoperation in patients with stress urinary incontinence: a multi-institutional electronic medical record database analysis
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Anne G. Sammarco, Rebecca L. James, Sangeeta T. Mahajan, Aisha K. Taylor, Penny Benchek, and David Sheyn
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Reoperation ,medicine.medical_specialty ,Urology ,Urinary Incontinence, Stress ,Specific risk ,MEDLINE ,Urinary incontinence ,Article ,Tobacco Use ,Gynecologic Surgical Procedures ,Risk Factors ,Internal medicine ,Diabetes mellitus ,medicine ,Electronic Health Records ,Humans ,Risk factor ,Asthma ,Retrospective Studies ,business.industry ,Obstetrics and Gynecology ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Obesity ,Surgery ,Female ,medicine.symptom ,business - Abstract
Recurrence rates of stress urinary incontinence after surgery are reported to be between 8 to 15%. Both surgical technique and non-surgical risk factors have been shown to affect post-operative outcomes. Tobacco use is a possible risk factor that may increase the surgical failure rate, however, there are currently conflicting reports in the literature regarding the affect of tobacco use on surgical outcomes. Our objective is to evaluate the effect of tobacco use on the risk of repeat surgery for stress urinary incontinence (SUI).We performed a retrospective cohort analysis using a de-identified clinical database from a large multi-institution electronic health records data web application EPM:ExploreTM (Explorys Inc, Cleveland, Ohio) to identify women with and without a history of tobacco use who underwent reoperation for stress urinary incontinence within 2 years of the first surgery. We then evaluated previously described risk factors for reoperation: diabetes mellitus (DM), pelvic organ prolapse (POP), anti-muscarinic (AM) use at initial surgery, obesity, and advanced age on rate of reoperation and the impact of tobacco use on these risk factors.Tobacco use was associated with an increased rate of a second surgery for SUI (OR=1.43, p0.001), as was anti-muscarinic use (OR = 1.68, p0.001), DM (OR = 1.21, p = 0.005), age50 years (OR= 1.16, p = 0.040), and BMI30 kg/m2 (OR = 2.97 p0.001). The odds of a second surgery for SUI in patients who used tobacco and anti-muscarinic medications or had pelvic organ prolapse were lower when compared to non-users. The odds of a second surgery for SUI were higher in patients who used tobacco and had asthma when compared to non-users who had asthma.Tobacco increases the overall risk of second surgery for SUI, however, in patients with specific risk factors, tobacco use is associated with a decrease risk of reoperation.
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- 2015
35. 13: The changing practice of hysterectomy and its effect on payments to hospitals among privately insured women in the United States
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Brahmajee K. Nallamothu, Anne G. Sammarco, E.K. Kobernick, Neil Kamdar, Daniel M. Morgan, Carolyn W. Swenson, and Helen Levy
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Gynecology ,medicine.medical_specialty ,Hysterectomy ,business.industry ,Family medicine ,media_common.quotation_subject ,medicine.medical_treatment ,medicine ,Obstetrics and Gynecology ,Payment ,business ,media_common - Published
- 2017
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36. 5A: Comparison of midsagittal cross sectional areas above and below the levators in women with and without prolapse
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A. Jankowski, Anne G. Sammarco, Carolyn W. Swenson, and John O.L. DeLancey
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Orthodontics ,business.industry ,Obstetrics and Gynecology ,Medicine ,business - Published
- 2017
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37. VRL, a Novel Environment for Control Engineering Practicing: An Application to a Fault Tolerant Control System
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Maria Letizia Corradini, Gianfranco Parlangeli, Andrea Manni, G. Sammarco, M. L., Corradini, G., Sammarco, A., Manni, and Parlangeli, Gianfranco
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Engineering ,business.industry ,Active learning (machine learning) ,Control engineering ,Fault tolerance ,Virtual reality ,computer.software_genre ,Inverted pendulum ,Fault tolerant control system ,Virtual machine ,business ,computer ,Computer animation ,Remote laboratory - Abstract
Virtual Remote Laboratory (VRL) is a powerful tool for an effective active learning in Control Engineering formation because it gives the opportunity of testing remotely control laws both by simulations within a virtual reality framework and by remote experiments. In this paper the virtual environment VRL is described and an application of a fault tolerant control law on an inverted pendulum is shown.
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- 2006
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38. The Bladder in MS: A Review
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Bogdan Orasanu, Sangeeta T. Mahajan, and Anne G. Sammarco
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medicine.medical_specialty ,Neurology ,Urinary symptoms ,business.industry ,Multiple sclerosis ,Urinary system ,Alternative medicine ,Urinary incontinence ,medicine.disease ,Omics ,Work-up ,medicine ,medicine.symptom ,Intensive care medicine ,business - Abstract
Urinary complaints are common in Multiple Sclerosis (MS), representing a large source of morbidity and financial burden for these patients. These issues can be complex and difficult to manage for the care provider. As new treatments develop, it is important to have a structured but flexible approach to the diagnosis and treatment of urinary symptoms. In this article we review the pathophysiology, symptoms, work up, and management options for the bladder in MS.
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- 2014
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39. Partnering with public schools: a resident-driven reproductive health education initiative
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Karen Ashby, Tao Y. Zhu, Anne G. Sammarco, Kelly Kuo, Shandhini Raidoo, and Lulu X. Zhao
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Male ,Safe Sex ,Health Knowledge, Attitudes, Practice ,Adolescent ,Attitude of Health Personnel ,media_common.quotation_subject ,education ,Population ,Psychological intervention ,Sexually Transmitted Diseases ,Sex Education ,Public-Private Sector Partnerships ,Birth control ,Nursing ,Pregnancy ,Medicine ,Humans ,Prospective Studies ,Cities ,Students ,Curriculum ,Socioeconomic status ,media_common ,Reproductive health ,Ohio ,education.field_of_study ,Schools ,business.industry ,Obstetrics and Gynecology ,Internship and Residency ,General Medicine ,Abstinence ,Self Efficacy ,Contraception ,Policy ,Pediatrics, Perinatology and Child Health ,Health education ,Female ,business - Abstract
To assess the impact of a resident-driven sexual health educational initiative in an inner-city Cleveland middle school.10 resident physicians and 57 students in 7(th) and 8(th) grade participated in this prospective cohort study.Residents taught 3 sessions on the topics of basic anatomy and physiology, pregnancy, sexually transmitted infections (STI), contraception, and safe relationships. Outcome measures included the percentages of students able to name at least 3 different STIs and contraceptive methods; to name potential complications of STIs; and to correctly identify condoms and abstinence as the only contraceptive methods also protective against STI transmission.Significant improvements were noted in students' baseline knowledge of human anatomy, contraception, and safe sex practices after completion of the curriculum. The percentage of students able to name at least 3 forms of birth control increased from 1.7% to 70.7% (P .0001). The percentage able to name at least 3 different STIs increased from 5.3% to 72.4% (P.0001). Follow-up testing 4 months after completion of the curriculum demonstrated significant knowledge retention. All residents and medical students surveyed described a perceived need for comprehensive-rather than abstinence-based-reproductive health education in schools.The socioeconomic burden of teen pregnancy justifies comprehensive efforts to improve reproductive health education.
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- 2013
40. Gastrectomia totale allargata. Quali indicazioni nel III millennio
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SANTANGELO, MICHELE, G. Vescio, L. Sommella, M. Battaglia, A. Valente, G. Sammarco, F. Bossa, E. T.r.i.g.g.i.a.n.i., Santangelo, Michele, G., Vescio, L., Sommella, M., Battaglia, A., Valente, G., Sammarco, F., Bossa, and E. T. r. i. g. g. i. a. n., I.
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Gastrectomia totale allargata - Abstract
BACKGROUND: Total extended gastrectomy (TEG) is indicated in the treatment of gastric cancer for necessity or to achieve an oncologic radicality. By this surgical treatment the stomach and other organs or a part of them involved by primitive tumor are removed. METHODS: The authors report a study about 15 patients, out of 116 cases of gastric cancer, operated by TEG between 1990-1998. The middle-age of this patients was 63 years (range 45-76) and their general conditions were good in 9 cases and not-good in 6. The postoperative total parenteral nutrition (TPN) was carried out in all the patients, while preoperatively only in the most compromised patients. The surgical treatments were: 2 TG (total gastrectomy)+splenecomy; 3 TG+splenectomy+pancreatic resection; 4 TG+splenectomy+pancreatic resection+distal esophageal resection; 1 TG+distal esophageal resection; 2 TG+atypic hepatic resection; 1 TG+ atypic hepatic resection+duodenum resection; 2 TG+large intestine resection. While 10 patients were operated on to obtain radicality, 5 patients had a palliative treatment. RESULTS: There was not perioperative mortality, but we have observed: one dehiscence of the duodenal stump and one pancreatic fistula treated with conservative therapy; one left subfrenic abscess treated with surgical therapy. The survival has been higher in the patients treated with radicality. On the basis of these cases, the authors consider: 1) the possibility to obtain radicality by TEG; 2) the gastric localizations more often associated to extravisceral neoplastic localization; 3) the role of extensive lymph node resection (III and IV level) to obtain oncological radicality or neoplastic reduction. CONCLUSIONS. On the basis of their personal experience and related literature, the authors conclude that TEG is indicated to: 1) obtain a better lymphadenectomy; 2) obtain an oncologic radicality; 3) reduce the neoplastic mass in order to facilitate adjuvant therapy; 4) avoid or treat neoplastic complications; 5) improve the quality of life.
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- 2001
41. Le cisti da echinococco primitive a localizzazione rara. Presentazione di due casi e revisione della letteratura
- Author
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SANTANGELO, MICHELE, G. Vescio, G. Sammarco, D. Cafaro, D. Gerbasi, E. T.r.i.g.g.i.a.n.i., Santangelo, Michele, G., Vescio, G., Sammarco, D., Cafaro, D., Gerbasi, and E. T. r. i. g. g. i. a. n., I.
- Subjects
surrene ,miza ,cisti da echinococco - Abstract
Hydatidosis is a parasitic disease. It's generally localized in the liver and in the lung even if any other organ can be potentially affected. From 92 to 98 our group observed two cases of rare primitive localisation of echinococcosis (one mediastinal and one retroperitoneal cyst). The patients performed serologic and instrumental exams to establish the right therapeutic strategy. Both of them were operated (it was carried out a pericystectomy with open cyst in one of them and an exeresis of the right adrenal gland including hydatid cyst in the other one). A patient underwent to Albendazole prophylaxis. During the follow-up the patients performed echography, CT and MRI. Considering the literature's data and their experience the authors emphasize: 1. The diagnosis of rare primitive localization of hydatidosis is very difficult. 2. The diagnostic iter requires a correct relationship between the laboratory and imaging data. 3. Only the exclusion of other localizations of the cyst (liver, lung or other organs) give us the possibility to diagnose a rare primitive localization of hydatidosis. 4. The treatment of hydatidosis is specifically surgical. 5. The surgeon can use several different approaches in relationship to the place and the anatomopathologic characters of the cyst.
- Published
- 1999
42. Another case of cystic fibrosis complicated by meconium ileus associated with Hirschsprung's disease: a rare and important association
- Author
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C. Esposito, C. De Fazio, A. Settimi, G. Sammarco, Francesca Alicchio, Esposito, Ciro, Sammarco, Giorgio, De Fazio, C., Alicchio, Francesca, and Settimi, Alessandro
- Subjects
Male ,Meconium ,congenital, hereditary, and neonatal diseases and abnormalities ,medicine.medical_specialty ,Cystic Fibrosis ,Day of life ,Meconium Ileus ,Disease ,digestive system ,Cystic fibrosis ,Gastroenterology ,Colonic Diseases ,Fatal Outcome ,Ileus ,Internal medicine ,Pediatric surgery ,medicine ,Humans ,Hirschsprung Disease ,Hirschsprung's disease ,business.industry ,Ileal Diseases ,Infant, Newborn ,General Medicine ,medicine.disease ,digestive system diseases ,Pediatrics, Perinatology and Child Health ,Surgery ,business - Abstract
We are reporting the case of a neonate which died on 16th day of life due to a fatal evolution of a rare association of cystic fibrosis and Hirschsprung's disease.
- Published
- 2008
43. Characterization of Cryphonectria parasitica populations in Southern Italy
- Author
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A. M. Pennisi, Santa Olga Cacciola, D. Spica, G. Sammarco, PENNISI AM, SAMMARCO G, SPICA D, and CACCIOLA SO
- Subjects
Genetic drift ,Ecology ,Chestnut blight ,Botany ,Cryphonectria ,Horticulture ,Biology ,biology.organism_classification ,Gene flow - Published
- 2005
44. The Bladder in MS: A Review
- Author
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G Sammarco, Anne, primary
- Published
- 2014
- Full Text
- View/download PDF
45. Environmental Accounting as a Communication and Management Tool
- Author
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M. Molinari, S. Ratti, and G. Sammarco
- Subjects
Engineering ,business.industry ,Environmental resource management ,Environmental economics ,Environmental data ,Environmental accounting ,Environmental Sustainability Index ,Environmental full-cost accounting ,media_common.cataloged_instance ,Balance sheet ,European union ,Environmental scanning ,business ,media_common ,Waste disposal - Abstract
International organisations such as United Nations and Euro-pean Union are developing methodologies that should be the starting point tor company environmental halanee sheet to draw up national environmental accounts.Fondazione ENI Enrico Mattei is working with ISTAT (Italian national statis-tical office) on a scheme of accounts for physical and mone-tary environmental data, finalised to integrate them with na-tional economic accounts, gathering information about the flows of inputs, products, waste streams and monetary values related to environmental issues. This methodology has been applied to hydrocarbons exploration and production activities and a software has been implemented in order to organise quantitative environmental data and current and capital envi-ronmental expenditures. The degree of data disaggregation is such as to fulfil complete balance sheets for each drilling site and for each gas and oil gathering centre: data can be also consolidated at a corporate level and used for environmental performance indicators. This detail increases the effectiveness of the company environmental accounting especially for planning and goal selling, as well as for external communi-cation.
- Published
- 1996
- Full Text
- View/download PDF
46. [Carcinoma of the gastroesophageal junction. General principles of surgical therapy]
- Author
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E, Triggiani, G, Liguori, G, Sammarco, V, Aloi, B S, Cavalcanti, M G, Cristofaro, S, Triggiani, and G, Vescio
- Subjects
Esophageal Neoplasms ,Gastrectomy ,Stomach Neoplasms ,Humans ,Neoplasm Invasiveness ,Esophagogastric Junction ,Gastric Fundus ,Adenocarcinoma ,Retrospective Studies - Abstract
On the basis of histo-pathological examinations of postoperative samples following gastrectomy for adenocarcinomas of the esophageal gastric junction, the usefulness of the abdominal approach for this kind of surgical treatment is questioned. Assessment is expressed with other authors about the need for an anatomo-surgical classification of the cardial region, and the need to standardise the different surgical approaches in relation to exeresis location and extent as well as for reconstructive procedures is stressed.
- Published
- 1990
47. [The use of Mersilene mesh in the treatment of giant laparoceles]
- Author
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G, Liguori, G, Sammarco, V, Aloi, B S, Cavalcanti, E, Peluso, S, Triggiani, C, Tomasello, G, Vescio, and E, Triggiani
- Subjects
Adult ,Male ,Postoperative Complications ,Polyethylene Terephthalates ,Phthalic Acids ,Humans ,Biocompatible Materials ,Female ,Middle Aged ,Surgical Mesh ,Hernia, Ventral ,Aged ,Polyethylene Glycols - Abstract
The paper reports on experience with the use of Mersilene mesh in 6 patients with giant laparoceles. Besides being physiologically compatible, Mersilene mesh is recommended when traditional techniques fail. The Rives technique was used, placing the prostheses between the posterior sheath and the rectus muscle; in one case it was inserted under the peritoneum. A good local and general preparation for the operation is recommended. Even though the introduction of prosthetic materials into the body is not always non-injurious, the use of Mersilene mesh is advised because of its easy positioning and the low incidence of complications.
- Published
- 1990
48. [Fistula following emergency total colectomy: an efficient method of treatment]
- Author
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G, Sammarco, V, Iaccarino, G, Liguori, V, Aloi, B S, Cavalcanti, M G, Cristofaro, S, Triggiani, V, Paletta, C, Tomasello, and G, Vescio
- Subjects
Adult ,Male ,Megacolon, Toxic ,Ethanol ,Ileal Diseases ,Hypertonic Solutions ,Intestinal Fistula ,Contrast Media ,Humans ,Colitis, Ulcerative ,Skin Diseases ,Colectomy - Abstract
A personal case of enterocutaneous fistula secondary to total emergency colectomy is reported with particular emphasis on an effective form of radiological management, based on the percutaneous sclerosing of the fistulous tract using absolute ethanol and a hyperosmotic contrast medium (Angioconray 80%). By this approach a rapid closure of the fistulous tract was obtained. Moreover the procedure was easy to perform, well tolerated by the patient and devoid of untoward side effects.
- Published
- 1990
49. The Foot in Diabetes
- Author
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James G. Sammarco
- Subjects
Surgery - Published
- 1992
- Full Text
- View/download PDF
50. [Diagnosis and follow-up of sclerodermatous esophagopathy by electromanometry]
- Author
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M, Delfino, F, Suppa, A, Tricarico, G, Sammarco, and E, Triggiani
- Subjects
Male ,Esophagus ,Scleroderma, Systemic ,Manometry ,Humans ,Female ,Esophageal Diseases ,Follow-Up Studies - Published
- 1984
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