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18 results on '"G. Daidola"'

1. A Case Report of AA Amyloidosis Associated With Familial Periodic Fever Syndrome Diagnosed After Kidney Transplantation: Never Say Never

Author

Antonio Lavacca, Luigi Biancone, G. Daidola, Giuseppe Paolo Segoloni, M. Messina, G. Restagno, and Andrea Ranghino

Subjects
Pathology, medicine.medical_specialty, Fever, Gastroenterology, Nephropathy, AA amyloidosis, Internal medicine, Biopsy, medicine, Humans, Kidney transplantation, Polycystic Kidney Diseases, Transplantation, Kidney, medicine.diagnostic_test, business.industry, Amyloidosis, medicine.disease, Kidney Transplantation, surgical procedures, operative, medicine.anatomical_structure, Surgery, Periodic fever syndrome, business, Nephrotic syndrome
Abstract

Recurrent or “de novo” AA amyloidosis in the renal allograft is rarely described. We describe a case of severe nephrotic syndrome in a recipient of a kidney graft with a previous diagnosis of polycystic nephropathy caused by AA amyloidosis diagnosed only after the renal transplantation. The disease was possibly a tumor necrosis factor receptor–associated periodic syndrome (TRAPS). TRAPS is a rare hereditary inflammatory disease never reported to the best of our knowledge, as a de novo diagnosis in the transplantation setting. Biopsy of the renal graft, indicated for the onset of heavy proteinuria, and genetic investigation provided the clues for diagnosis.

Published
2013

2. Transplantation: clinical studies - A

Author

T. Yildirim, R. Yilmaz, M. Altindal, E. Turkmen, M. Arici, B. Altun, Y. Erdem, O. Guliyev, M. Erkmen Uyar, E. Tutal, Z. Bal, S. Sezer, U. Bal, B. Say n, B. Erdemir, A. O'Rourke-Potowki, N. Gauge, H. Penny, A. Cronin, S. Frame, D. J. Goldsmith, J. A. Yagan, A. Chandraker, R. M. Velickovic Radovanovic, A. Catic Djordjevic, B. Mitic, N. Stefanovic, T. Cvetkovic, N. Serpieri, F. Grosjean, G. Sileno, M. Torreggiani, V. Esposito, F. Mangione, M. Abelli, F. Castoldi, D. Catucci, C. Esposito, A. Dal Canton, A. V. Vatazin, A. B. Zulkarnaev, C. Borst, Y. Liu, J. Thoning, M. Tepel, C. Libetta, E. Margiotta, I. Borettaz, M. Canevari, C. Martinelli, E. Lainu, F. Meloni, V. Sepe, R. Miguel Costa, E. Vasquez Martul, J. Reboredo, C. Rivera, F. Simonato, G. Tognarelli, G. Daidola, E. Gallo, M. Burdese, V. Cantaluppi, L. Biancone, G. P. Segoloni, M. Priora, M. Messina, M. Tamagnone, A. Linsalata, A. Lavacca, G. Segoloni, W. Zuidema, R. Erdman, J. van de Wetering, F. Dor, J. Roodnat, E. Massey, L. Timmerman, J. IJzermans, W. Weimar, C. Sibley-Allen, R. Hilton, M. Moghul, L. Burnapp, G. Blake, T. Y. Koo, J.-S. Park, H. C. Park, G.-H. Kim, C. H. Lee, I. H. Oh, C. M. Kang, J. K. Hwang, S. C. Park, B. S. Choi, H. J. Chun, J. I. Kim, C. W. Yang, I. S. Moon, S. Van Laecke, W. Van Biesen, E. V. Nagler, Y. Taes, P. Peeters, R. Vanholder, R. Pruthi, R. Ravanan, A. Casula, M. Harber, P. Roderick, D. Fogarty, A. Cho, J.-h. Shin, H. R. Jang, J. E. Lee, W. Huh, D. J. K. Kim, H. Y. Oh, Y.-G. Kim, A. Sancho Calabuig, E. Gavela Martinez, J. Kanter Berga, S. Beltran Catalan, A. I. Avila Bernabeu, L. M. Pallardo Mateu, E. Gonzalez, N. Polanco, M. Molina, E. Gutierrez, L. Garcia Puente, A. Sevillano, E. Morales, M. Praga, A. Andres, M. Banasik, M. Boratynska, K. Koscielska-Kasprzak, D. Bartoszek, M. Myszka, S. Zmonarski, B. Nowakowska, E. Wawrzyniak, A. Halon, P. Chudoba, M. Klinger, J. Rojas-Rivera, J. M. Morales, J. Egido, C. M. Kopecky, M. Haidinger, C. Kaltenecker, M. Antlanger, G. Marsche, M. Holzer, J. Kovarik, J. Werzowa, M. Hecking, M. D. Saemann, J. M. Kim, E. S. Koh, B. H. Chung, Y. S. Kim, M. Krajewska, O. Mazanowska, D. Kaminska, M. Zabinska, B. Malkiewicz, D. Patrzalek, J. Sulowicz, S. Szostek, A. Wojas-Pelc, E. Ignacak, W. Sulowicz, V. Bellizzi, P. Calella, A. Cupisti, A. Capitanini, C. D'Alessandro, D. Giannese, A. Camocardi, G. Conte, M. Barsotti, G. Bilancio, R. Luciani, L. Locsey, I. Seres, D. Kovacs, L. Asztalos, G. Paragh, M. Wohlfahrtova, P. Balaz, S. Rokosny, P. Wohlfahrt, A. Bartonova, O. Viklicky, J. Kers, R. B. Geskus, L. J. Meijer, F. Bemelman, I. J. M. ten Berge, S. Florquin, J.-C. Hwang, M.-Y. Jiang, Y.-H. Lu, S.-F. Weng, A. Testa, G. Porto, M. Sanguedolce, B. Spoto, R. Parlongo, A. Pisano, G. Enia, G. Tripepi, C. Zoccali, N. Mamode, A. Lennerling, F. Citterio, K. Van Assche, S. Sterckx, M. Frunza, H. Jung, A. Pascalev, R. Johnson, C. Loven, T. Soleymanian, H. Keyvani, S. M. Jazayeri, Z. Fazeli, S. Ghamari, M. Mahabadi, V. Chegeni, I. Najafi, M. R. Ganji, K. M. E. Meys, J. W. Groothoff, K. Jager, F. Schaefer, B. Tonshoff, C. Mota, K. Cransberg, K. van Stralen, E. Gurluler, N. Gures, A. Alim, A. Gurkan, U. Cakir, I. Berber, R. Caluwe, E. Nagler, B. Van Vlem, A. Betkowska-Prokop, M. Kuzniewski, M. Krzanowski, I. Masson, M. Flamant, N. Maillard, E. Cavalier, O. Moranne, E. Alamartine, C. Mariat, P. Delanaye, L. L. Canas Sole, E. Iglesias Alvarez, M. C. M. C. Pastor, F. F. Moreno Flores, V. V. Abujder, F. F. Graterol, J. J. Bonet Sol, R. R. Lauzurica Valdemoros, M. Yoshikawa, K. Kitamura, K. Nakai, S. Goto, H. Fujii, T. Ishimura, M. Takeda, M. Fujisawa, S. Nishi, N. Prasad, D. Gurjer, D. Bhadauria, A. Gupta, R. Sharma, A. Kaul, M. Cybulla, M. West, K. Nicholls, J. Torras, G. Sunder-Plassmann, S. Feriozzi, S. Lo, P. Y. H. Wong, D. Ip, C. K. Wong, V. C. C. Chow, S. K. L. Mo, M. Molnar, A. Ujszaszi, M. E. Czira, M. Novak, I. Mucsi, J. M. Cruzado, S. Coelho, N. Porta, O. Bestard, E. Melilli, O. Taco, I. Rivas, J. Grinyo, L.-M. Pouteau, J.-M. N'Guyen, A. Hami, M. Hourmant, N. Ghahramani, Z. Karparvar, S. Shadrou, M. Ghahramani, J. P. Fauvel, A. Hadj-Aissa, F. Buron, E. Morelon, M. Ducher, C. Heine, P. Glander, H.-H. Neumayer, K. Budde, L. Liefeldt, N. Montero, A. C. Webster, A. Royuela, J. Zamora, M. Crespo, J. Pascual, A. Y. Adema, W. T. H. van Dorp, M. J. K. Mallat, H. W. de Fijter, Y. A. Hong, C. W. Park, Y.-S. Kim, G. Suleymanlar, Z. Uzundurukan, A. Kapuagas, I. Sencan, R. Akdag, A. Torio, V. Mas, M. J. Perez-Saez, M. Mir, A. Faura, O. Montes-Ares, M. D. Checa, D. Sawinski, J. Trofe-Clark, T. Sparkes, P. Patel, S. Goral, R. Bloom, H. J. Kim, S. J. Park, T. H. Kim, Y. W. Kim, Y. H. Kim, S. W. Kang, M. Abdel Halim, O. Gheith, T. Al-Otaibi, A. Mosaad, W. Awadeen, T. Said, P. Nair, and M. R. N. Nampoory

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, Medicine, business, Intensive care medicine
Published
2013

3. Renal histopathology

Author

F. Marie-Lucile, N. Laure-Helene, C. Yosr, M. Anne, F. Fadi, C. Levi, V. Meas-Yedid, C. Daniliuc, A. Karras, J. C. Olivo-Marin, L. Mouthon, E. Guiard, M. Roland, L. Guillevin, C. Jacquot, D. Nochy, E. Thervet, Q. Chen, C. Skerka, B. Uzonyi, S. Lindner, C. Licht, B. Hoppe, M. Riedl, M. Kirschfink, S. Habbich, G. Wolf, L. Strain, T. H. Goodship, P. F. Zipfel, H. Kfoury, A. Alsuwaida, K. Alsaad, F. Alhejaili, M. Alghonaim, J. Alwakeel, S. Husain, N. Aloudah, L. Besso, M. Tamagnone, G. Daidola, M. Burdese, L. Repetto, G. Pasquale, L. Colla, L. Biancone, P. Stratta, G. P. Segoloni, J. Bacalja, A. M. Bauer Segvic, S. Bulimbasic, A. Pacic, M. Knotek, M. Sabljar Matovinovic, K. Galesic, D. Galesic Ljubanovic, E. Zakharova, E. Stolyarevich, O. Vorobjova, H. Tamouza, J. M. Chemouny, M. Flamant, L. Raskova Kafkova, M. Demion, M. Laurent, F. Walker, B. A. Julian, E. Tissandie, M. K. Tiwari, J. Novak, N. O. Camara, M. Benhamou, F. Vrtovsnik, R. C. Monteiro, I. C. Moura, S. Samavat, P. Ahmadpoor, P. Torbati, R. Ghaderi, F. Poorrezagholi, F. Samadian, M. Nafar, A. MII, A. Shimizu, T. Kaneko, F. Yasuda, M. Fukui, Y. Masuda, Y. Iino, Y. Katayama, C. Muller, J. Markovic-Lipkovski, S. Simic-Ogrizovic, R. Naumovic, S. Cirovic, D. Mitrovic, G. Muller, A. Wozniak, M. Janicka-Jedynska, J. Zurawski, E. Kaczmarek, J. Zachwieja, S. Khilji, T. Dorman, P. O'kelly, L. Lampty, K. Leung, A. Shadivan, C. Varghese, J. Walshe, T. Saito, M. Kawano, T. Saeki, I. Mizushima, Y. Yamaguchi, N. Imai, H. Nakashima, H. Umehara, M. Shvetsov, O. Popova, N. Chebotareva, A. Ivanov, I. Bobkova, D. Cremasco, M. Ceol, L. Peruzzi, G. Mazzucco, M. Giuseppina, G. Vezzoli, R. Cristofaro, A. D'angelo, F. Anglani, D. Del Prete, G. Coppolino, N. Comi, D. Bolignano, V. Piraina, R. Talarico, A. Colombo, G. Lucisano, G. Fuiano, P. Bernich, A. Lupo, T. R. Of Renal Biopsies, M. P. Rastaldi, O. C. Jercan, P. Messa, D. Alexandru, L. Mogoanta, and V. Uribe Villegas

Subjects
Transplantation, Nephrology
Published
2012

4. Transplantation - clinical I

Author

M. Bonani, J. Brockmann, C. D. Cohen, T. Fehr, A. Nocito, M. Schiesser, A. L. Serra, M. Blum, M. Struker, D. F. Frey, R. P. Wuthrich, Y. W. Kim, S. J. Park, T. H. Kim, Y.-H. Kim, S. W. Kang, L. Webb, A. Casula, C. Tomson, Y. Ben-Shlomo, H. Mansour, A. Akl, E. Wafa, M. El Shahawy, R. Palma, S. Swaminathan, A. B. Irish, A. Kolonko, J. Chudek, A. Wiecek, Y. Vanrenterghem, D. Kuypers, D. V. Katrien, P. Evenepoel, K. Claes, B. Bammens, B. Meijers, M. Naesens, S. Lo, C.-K. Chan, D. Yong, P.-N. Wong, T.-H. Kwan, Y.-L. Cheng, K.-S. Fung, B.-Y. Choy, K.-F. Chau, C.-B. Leung, J. Ebben, J. Liu, S.-C. Chen, A. Collins, Y.-W. Ho, M. Abelli, A. Ferrario DI Torvajana, E. Ticozzelli, B. Maiga, A. Patane, P. Albrizio, M. Gregorini, C. Libetta, T. Rampino, P. Geraci, A. Dal Canton, M.-T. Rotter, J. Jacobi, K. Pressmar, K. Amann, K.-U. Eckardt, A. Weidemann, K. Muller, M. Stein, C. Diezemann, A. Sefrin, N. Babel, P. Reinke, T. Schachtner, C. Costa, G. A. Touscoz, F. Sidoti, F. Sinesi, S. Mantovani, S. Simeone, C. Balloco, E. Piasentin Alessio, M. Messina, G. Segoloni, R. Cavallo, R. .K. Sharma, D. A. Kaul, R. K. Gupta, A. Gupta, N. Prasad, D. Bhadhuria, K. J. Suresh, S. Benaboud, D. Prie, E. Thervet, S. Urien, C. Legendre, J.-C. Souberbielle, D. Hirt, G. Friedlander, J.-M. Treluyer, M. Courbebaisse, M. Arias, J. Campistol, J. Pascual, J. M. Grinyo, D. Hernandez, J. M. Morales, L. M. Pallardo, D. Seron, L. Senecal, A. Boucher, R. Dandavino, S. Colette, M. Vallee, J.-P. Lafrance, Y. Tung-Min, W. Min-Ju, C. Cheng-Hsu, C. Chi-Hung, S. Kuo-Hsiung, W. Mei-Chin, S. Direkze, M. Khorsavi, S. Stuart, A. Goode, G. Jones, C. Massimetti, I. Napoletano, G. Imperato, M. T. Muratore, S. Fazio, G. Pessina, F. Brescia, S. Feriozzi, K. Tanaka, K. Sakai, A. Futaki, Y. Hyoudo, M. Muramatsu, T. Kawamura, S. Shishido, S. Hara, A. Kushiyama, A. Aikawa, K. Jankowski, J. Gozdowska, D. Lewandowska, A. Kwiatkowski, M. Durlik, P. Pruszczyk, Y. Obi, N. Ichimaru, T. Kato, M. Okumi, J. Kaimori, K. Yazawa, N. Nonomura, Y. Isaka, S. Takahara, M. Aimele, R. Christophe, D. Geraldine, R. Eric, H. Alexandre, I. Masson, M. Nicolas, T. Ivan, J. Acil, T. Lise, H.-A. Aoumeur, D. Laurence, D. Pierre, C. Etienne, R. Lionel, K. Nassim, M. Emmanuel, A. Eric, M. Christophe, K. Alexandre, B. Pierre, H. Jean-Philippe, P. Dominique, L. Christophe, G. Alexei, D. Michel, P. Shah, V. B. Kute, A. Vanikar, M. Gumber, P. Modi, H. Trivedi, J. GoIebiewska, A. Debska-Slizien, B. Rutkowski, L. Domanski, G. Dutkiewicz, K. Kloda, A. Pawlik, A. Ciechanowicz, A. Binczak-Kuleta, J. Rozanski, M. Myslak, K. Safranow, K. Ciechanowski, C. S. Aline, T. Basset, X. Delavenne, E. Alamartine, C. Mariat, K. Bobrek-Lesiakowska, M. Wisniewska, M. Romanowski, M. Kurzawski, M. De Borst, L. Baia, G. Navis, S. Bakker, A. Ranghino, G. Tognarelli, E. Basso, A. M. Manzione, G. Daidola, G. P. Segoloni, T. Kimura, T. Yagisawa, N. Ishikawa, Y. Sakuma, T. Hujiwara, A. Nukui, M. Yashi, J. H. Kim, S.-S. Kim, D. J. Han, S.-K. Park, G. Randhawa, H. Patel, S. Taheri, O. Goker-Alpan, J. Ibrahim, K. Nedd, S. Shankar, H. Lein, B. Barshop, E. Boyd, M. Holida, R. Hillman, R. Mardach, N. Wienreb, B. Rever, R. Forte, A. Desai, A. Wijatyk, P. Chang, and R. Martin

Subjects
Transplantation, Nephrology
Published
2012

5. A newly identified mutation in the complement factor I gene not associated with early post-transplant recurrence of atypical hemolytic-uremic syndrome: a case report

Author

M. Messina, Ana Maria Manzione, G. Daidola, Elisa Basso, Andrea Ranghino, G. Tognarelli, and Segoloni Gp

Subjects
Adult, Male, Basiliximab, Complement factor I, Biology, urologic and male genital diseases, Recurrence, hemic and lymphatic diseases, Atypical hemolytic uremic syndrome, medicine, Humans, Kidney transplantation, Atypical Hemolytic Uremic Syndrome, Transplantation, CD46, medicine.disease, Kidney Transplantation, Tacrolimus, Complement Factor I, Factor H, Immunology, Hemolytic-Uremic Syndrome, Mutation, Surgery, medicine.drug
Abstract

Atypical hemolytic uremic syndrome (aHUS), which can recur after renal transplantation, is associated with poor graft outcomes. The underlying genetic defect, namely, mutations in genes coding for the complement factor H, I (CFI), or membrane cofactor protein, greatly impacts the risk of aHUS recurrence. We report here the case of a patient with chronic renal failure due to aHUS in which screening for complement mutations, performed before wait-listing for kidney transplantation, showed a never described previously heterozygous mutation in the exon II of the CFI gene. Specifically, this mutation leads to a substitution of cytosine for guanosine at nucleotide 148, resulting in the change at amino acid 50 from arginine to proline. Subsequently, he received a renal allograft from deceased donor. Good graft function was established immediately, without clinical features of aHUS. Due to a lack of data on this mutation, we avoided prophylactic treatment for aHUS but closely monitored biochemical markers of aHUS to treat a possible recurrence. Immunosuppressive treatment was based on basiliximab, tacrolimus, steroids, and mycophenolic acid. At the time of discharge the serum creatinine was 1.4 mg/dL. Ten months after transplantation the patient is doing well without evidence of aHUS. Our case suggested that a heterozygous mutation in exon II of the CFI gene was not associated with a risk of early post-transplant aHUs recurrence adding new knowledge on complement mutations implicated in aHUS post-transplant recurrences.

Published
2013

6. Clinical Nephrology: primary and secondary glomerulonephritis

Author

Maria Stangou, Aki Kuroki, Magdalena Silska, Meg Jardine, Rosanna Coppo, Helen Liakou, Alessandra Grosso, Marco Di Girolamo, Masanori Ito, Domingo Hernández, H. Marco, Y. Arce, Kenji Ito, Paolo Lorusso, Cátia Pêgo, Marco Quaglia, Jacek Zachwieja, Heejung Choi, Salvatore Di Paolo, Domniki Ekonomidou, John Feehally, Ladislava Grcevska, Lidia Kozlovskaya, Hirotsugu Iwatani, Libor Vítek, Andrzej Blumczynski, Guido Ricchiuti, Jana Švarcová, Hala Kfoury, Marian Klinger, Rachele Gallo, Manoj R. Gumber, Eleni Rizopoulou, Timothy S. Johnson, Edgar Lorga, B. Laurent, Elisa Colombini, J.M. Llobet, Momir Polenakovic, Marta Kalousová, Elena Shakhnova, Caili Wang, Peter Heering, Rafid Tofik, Kentaro Ohtoshi, Elena Potencz, Nan Chen, Yaowen Xu, Grazia Vocino, N.L. Kozlovskaya, Alina Casian, Patricia Rullier, Sukran Gurses, Afroditi Pantzaki, Adamasco Cupisti, Bernardo Faria, Vladimir Nikolov, Alice C. Smith, Jakub Zavada, Eva Jancova, Anna Musielak, KyungHwan Jeong, Jessica N. Ivany, Adeline Lacraz, Eduardo B. Coelho, Junying Fan, Silvia Velciov, Tatsuya Shoji, Ju-Young Moon, Kazuo Kitamura, Masahiro Yamamoto, A. Jin Cho, Licia Peruzzi, Martina Giorgetti, Maria Svelto, Valentina Daprà, Natalia Meteleva, Katarzyna Lipkowska, Hong Ren, Jung Eun Lee, Christos Bantis, Panagiotis Patinakis, Himanshu V Patel, Noura AlOudah, Corina Vernic, Richard J. Johnson, Hiroyuki Komatsu, Gheorghe Gluhovschi, Young Tai Shin, Carla Lima, Anhar Ullah, Miltiadis Gerolymos, Gianna Mazzucco, Ilaria Cipollini, Stefan H. Jacobson, Katarzyna Koscielska-Kasprzak, Elena Kamyshova, Pavel Avdonin, Atsushi Yamauchi, Yuji Sato, Yasuhiro Date, Wladimir Szpirt, Eva Honsova, Niya Jia, Henrik Braunitzer, Hye Ryoun Jang, Polina Semenovylh, Yasuhiro Abe, Pankaj R Shah, Qianying Zhang, Larisa Bobrova, Josep M. Grinyó, Sérgio Lemos, Yoshimitsu Yamasaki, Hakan Yavas, Oktawia Mazanowska, Yoshitaka Rakugi, Tadao Akizawa, David Launay, Sang-Ho Lee, Grazia Tamma, R. Poveda, Kang Wook Lee, F.N. Vigotti, Pantelitsa Kalliakmani, Gyl Eanes Barros Silva, Ha Young Oh, Ji Yoon Jung, Florica Gadalean, Saori Nishio, Hargovind L Trivedi, Marten Trendelenburg, Nadia Sami, Yukihiro Wada, Christina Schwandt, Michalis Spartalis, Antoine Huart, Aurélie Hummel, Elisa Loiacono, Linghong Huang, Kostas Pliakos, Marios Papasotiriou, Nicoletta-Maria Kouri, Zdenka Hruskova, Jesus Garrido, Domniki Oikonomidou, M. Picazo, Jacek Manitius, Joachim Lundahl, George Efstratiadis, Alfons Segarra, Giovanni Sorbo, Ivan Topchii, Kamal K. Kaswan, Ole Torffvit, G. Daidola, Danuta Ostalska-Nowicka, Dimitrios Memmos, Valentina Panetta, Patrice Cacoub, YangGyoon Kim, Daniel Cioca, Manuela Bianciotto, Massimo Papale, Vladimira Bednarova, Naoto Katakami, Lina Muzi, Osman Z. Sahin, Javeria Peracha, Satoru Ogahara, Katrin Ivens, Shouichi Fujimoto, Ilona Kaszás, Giovanna Pasquariello, Demetris Christou, Jean-Emmanuel Kahn, Magdalena Grajewska, Xiaoxia Pan, Grazyna Odrowaz-Sypniewska, Arata Horii, Hiromi Rakugi, Elena Lazar, Helena Mareckova, Eliska Potlukova, Giuseppe Grandaliano, L. C. Rump, József Arányi, Dinesh Gera, Valeria T. Okino, Xiaonong Chen, Dong Seok Jang, Andrey Nesen, Dilek Gibyeli Genek, M. Diaz, Marcelina Zabinska, Ligia Petrica, Isabelle Marie, Dae Joong Kim, Pingyan Shen, Olivier Hinschberger, Sulra Lee, Virginia Trandafirescu, Ilona Dziemianko, Won Ik Jang, Ying Wang, Hiroshi Ohno, L. Besso, L. Colla, Dae Eun Choi, Natalia Tchebotareva, Gordana Petrusevska, Ryohei Yamamoto, Rifki Ersoy, Aida Afiani, Enyu Imai, Domenica Lasorsa, Paola Mattei, Maurizio Innocenti, Tânia Sousa, Xavier Fulladosa, Weiming Wang, Ágnes Haris, Maho Watanabe, Michael Walsh, Kálmán Polner, Shinji Fukuda, Annamaria D'Apollo, Atilla Uzum, Margherita Conrieri, Martin Lenicek, Valentina Galchinskaya, Yancun Li, Romana Rysava, Young Rok Ham, Joana Vidinha, Dorota Kaminska, Yoshitaka Isaka, Loredana Colla, Orhan Yucel, Irina Bobkova, Elen Almeida Romão, Beata Sulikowska, Jonathan Barratt, Carmen Vozmediano, ChunGyoo Ihm, Joan Torras, Cristiana Rollino, Itziar Navarro, Takao Saito, Funda Alkan Tasli, Kamal Goplani, Hidetoshi Ito, Frank Bridoux, Elisa Caramello, Mustafa Cirit, Alfred Warzywoda, Francesca M. Bosetti, Yoon-Goo Kim, Manuel Praga, Francois Berthoux, Fabrice Bonnet, Maria Teresa Rocchetti, M. Gomà, B. Svobodova, Zoltán Merán, Miguel Moysés Neto, Benjamin Terrier, Wen Zhang, Pinar Yeniay, Takao Koike, Kenichiro Iio, Olga Li, Lisa Mastrofrancesco, Mikhail Shvetsov, Reiko Hayaishi-Okano, Natalia Chebotareva, Francisco Rivera, Wooseong Huh, Giuseppe Paolo Segoloni, Magdalena Krajewska, Laura Morando, Osvaldo Merege Vieira Neto, Vladimir Tesar, Pauline Belenotti, Lise Thibaudin, Juan Manuel Lopez, Satu Sinikka Pesickova, Qiuhua Huang, Sigrid Lundberg, Christophe Mariat, K. Pinar Ozen, Tatiana Rudenko, Gheorghe Bozdog, Yingying Xie, Masao Kikuchi, Giovanna Valenti, Iva Gunnarsson, Abdulkareem Alsuwaida, Jan Penar, Bengt Rippe, Yoshiharu Tsubakihara, Xiao Li, Jolanta Soltysiak, Mohammed Alghonaim, Luc Saint-Martin, G.P. Segoloni, Loreto Gesualdo, Sufia Hussain, Hesham Mohey, Antonio Pasquariello, Sarah Chung, Francesco Quarello, Omran Bakoush, Miho Kimachi, Elena Khafizova, Roberta Camilla, Ida Valentina Suriano, Cristina Gluhovschi, M. Córica, Flaviu Bob, J. Ballarin, Hidenori Inohara, Maria Grazia Chiappini, Karen Molyneux, Eriko Kinugasa, Rosana Gelpi, Dimitrios S. Goumenos, Alessandro Amore, Piero Stratta, Ki Ryang Na, David Jayne, Liliane Ngango, Emmanuelle Plaisier, Anna Bottai, Antai Zheng, Aruna V. Vanikar, Rafał Donderski, Tae-Won Lee, Raffaella Cravero, Márcio Dantas, Yasuyuki Nagasawa, Giuliano Barsotti, Hiroaki Ogata, H. Hakan Yavas, Vaios Sigounas, and Fang Zhong

Subjects
Transplantation, medicine.medical_specialty, Primary (chemistry), Nephrology, business.industry, Internal medicine, medicine, Glomerulonephritis, Clinical nephrology, medicine.disease, business
Published
2011

7. POSITRON EMISSION TOMOGRAPHY AS A CLINICAL TOOL FOR THE 'TAILORED' MANAGEMENT OF RETROPERITONEAL FIBROSIS

Author

A. Volpe, V. Arena, G. Daidola, R.M. Scarpa, Cecilia Maria Cracco, Susanna Grande, E. Pelosi, F. Ragni, G.B. Piccoli, Cesare Marco Scoffone, E. Castellani, E. Gallo, and F. Porpiglia

Subjects
medicine.medical_specialty, medicine.diagnostic_test, business.industry, Positron emission tomography, Urology, Medicine, Radiology, medicine.symptom, Nuclear medicine, business, Retroperitoneal fibrosis, Preclinical imaging
Published
2008

8. [Efficacy of SUPRA HFR in the treatment of acute renal damage during multiple myeloma].

Author

Daidola G, Guarena C, Brustia M, Leonardi G, Vigotti FN, Marciello A, Bianco S, Chiarinotti D, Saltarelli M, Besso L, and Biancone L

Subjects
Acute Kidney Injury etiology, Aged, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Combined Modality Therapy, Female, Humans, Immunoglobulin Light Chains metabolism, Male, Middle Aged, Multiple Myeloma drug therapy, Myeloma Proteins metabolism, Plasmapheresis, Treatment Outcome, Acute Kidney Injury therapy, Hemodiafiltration methods, Multiple Myeloma complications
Abstract

Acute Kidney Injury (AKI) is a frequent complication of multiple myeloma (MM) with unfavorable prognostic significance. Light chains removal, combined with hematological therapy (CT) seems to offer significant benefits to renal function recovery (RFR). The SUPRA HFR, through the combination of high cut-off membrane without albumin loss and adsorbent cartridge, represents one of the "emerging" light chain removal methods. We report our multicentric retrospective experience with SUPRA HFR in 7 MM patients. At the end of the treatment with SUPRA HFR a significant reduction in serum free light chains compared to baseline was observed (min 24%; max 90%; median 74%). Despite a not always early start of the treatment, all patients recovered renal function with withdrawal from dialysis in 6/7 cases. Our preliminary experience of a combination of SUPRA HFR treatment with CT in 7 MM patients with AKI showed a significative renale functional recovery, with favourable cost/benefit ratio and a simple treatment schedule. These encouraging data suggest to further extend such treatment option, waiting for larger studies in this field., (Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.)

Published
2018

9. [Severe lactic acidosis requiring continuos haemodiafiltration in a young patient with unrecognized metabolic abnormality. Case report].

Author

Vigotti FN, Daidola G, Marciello A, Berruto F, Rizzuto A, Reina E, Perosa PM, and Saltarelli M

Subjects
Acidosis, Lactic etiology, Adult, Fructose adverse effects, Fructose-1,6-Diphosphatase Deficiency blood, Fructose-1,6-Diphosphatase Deficiency complications, Fructose-1,6-Diphosphatase Deficiency diet therapy, Fructose-Bisphosphatase blood, Genes, Recessive, Gluconeogenesis, Humans, Hypoglycemia complications, Male, Acidosis, Lactic therapy, Fructose-1,6-Diphosphatase Deficiency diagnosis, Hemodiafiltration
Abstract

Background: Lactic acidosis (LA) is the most common form of metabolic acidosis, defined by lactate values greater than 5 mmol/L and pH<7.34. The pathogenesis of LA involves hypoxic causes (type A) and non-hypoxic (type B), often coexisting. Identification and removal of the trigger are mandatory in the therapeutic management of LA. The case: A 38 years-old male patient entered the Emergency Ward for dyspnea, fever, vomiting and hyporexia. An important respiratory distress with hyperventilation due to severe LA was found, together with severe hypoglicemia, without renal impairment. Past medical history unremarkable, except for reported episodic hypoglicemia in the childhood, with fructose "intolerance", without any other data. No evidence of intoxications, septic shock or significant cytolysis. No drugs causing LA. The patient underwent orotracheal intubation, glucose infusion, and continuous haemodiafiltration for 36-hrs. A rapid general improvement was obtained with stabilization of acid-base balance. A diagnosis of fructose-1,6-diphosphatase deficiency was made. It is an autosomical recessive gluconeogenesis abnormality, with recurrent episodes of hypoglicemia and lactic acidosis after fasting, potentially lethal. The therapy is based on avoiding prolonged fasts, glucose infusion, and a specific diet, rich in glucose without fructose intake., Conclusions: The presence of not-otherwise-explained lactic acidosis in young patients has to place the suspect of an underlying and unknown metabolic derangement; in these cases, the involvement of the nephrologist appears to be pivotal for the differential diagnosis of the abnormalities of the acid-base balance, and for setting the best treatment., (Copyright by Società Italiana di Nefrologia SIN, Rome, Italy.)

Published
2018

10. Mitochondrial neurogastrointestinal encephalomyopathy treated with peritoneal dialysis and bone marrow transplantation.

Author

Ariaudo C, Daidola G, Ferrero B, Guarena C, Burdese M, Segoloni GP, and Biancone L

Subjects
Fatal Outcome, Female, Humans, Intestinal Pseudo-Obstruction diagnosis, Mitochondrial Encephalomyopathies diagnosis, Muscular Dystrophy, Oculopharyngeal, Ophthalmoplegia congenital, Young Adult, Bone Marrow Transplantation, Intestinal Pseudo-Obstruction therapy, Mitochondrial Encephalomyopathies therapy, Peritoneal Dialysis
Abstract

Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare disease caused by thymidine phosphorylase deficiency which leads to toxic accumulations of thymidine (dThd) and deoxyuridine (dUrd). It lacks an established treatment and the prognosis is traditionally poor. We report a case of a young female patient with normal renal function and MNGIE treated by peritoneal dialysis (PD) and allogeneic bone marrow transplantation (BMT). PD was effective in reducing dThd and dUrd plasma levels and in improving clinical symptoms. To our knowledge, this is the first report on the beneficial effects of PD regarding MNGIE neurological symptoms. PD, therefore, should be considered especially in medically compromised patients as a supportive treatment to improve clinical conditions before BMT.

Published
2015
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11. Low-protein diets in CKD: how can we achieve them? A narrative, pragmatic review.

Author

Piccoli GB, Vigotti FN, Leone F, Capizzi I, Daidola G, Cabiddu G, and Avagnina P

Abstract

Low-protein diets (LPDs) have encountered various fortunes, and several questions remain open. No single study, including the famous Modification of Diet in Renal Disease, was conclusive and even if systematic reviews are in favour of protein restriction, at least in non-diabetic adults, implementation is lagging. LPDs are considered difficult, malnutrition is a threat and compliance is poor. LPDs have been reappraised in this era of reconsideration of dialysis indications and timing. The definition of a normal-adequate protein diet has shifted in the overall population from 1 to 1.2 to 0.8 g/kg/day. Vegan-vegetarian diets are increasingly widespread, thus setting the groundwork for easier integration of moderate protein restriction in Chronic Kidney Disease. There are four main moderately restricted LPDs (0.6 g/kg/day). Two of them require careful planning of quantity and quality of food: a 'traditional' one, with mixed proteins that works on the quantity and quality of food and a vegan one, which integrates grains and legumes. Two further options may be seen as a way to simplify LPDs while being on the safe side for malnutrition: adding supplements of essential amino and keto acids (various doses) allows an easier shift from omnivorous to vegan diets, while protein-free food intake allows for an increase in calories. Very-low-protein diets (vLPDs: 0.3 g/kg/day) combine both approaches and usually require higher doses of supplements. Moderately restricted LPDs may be adapted to virtually any cuisine and should be tailored to the patients' preferences, while vLPDs usually require trained, compliant patients; a broader offer of diet options may lead to more widespread use of LPDs, without competition among the various schemas.

Published
2015
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12. A case report of AA amyloidosis associated with familial periodic fever syndrome diagnosed after kidney transplantation: never say never.

Author

Messina M, Daidola G, Restagno G, Lavacca A, Ranghino A, Biancone L, and Segoloni GP

Subjects
Fever diagnosis, Humans, Polycystic Kidney Diseases surgery, Amyloidosis complications, Fever complications, Kidney Transplantation
Abstract

Recurrent or "de novo" AA amyloidosis in the renal allograft is rarely described. We describe a case of severe nephrotic syndrome in a recipient of a kidney graft with a previous diagnosis of polycystic nephropathy caused by AA amyloidosis diagnosed only after the renal transplantation. The disease was possibly a tumor necrosis factor receptor-associated periodic syndrome (TRAPS). TRAPS is a rare hereditary inflammatory disease never reported to the best of our knowledge, as a de novo diagnosis in the transplantation setting. Biopsy of the renal graft, indicated for the onset of heavy proteinuria, and genetic investigation provided the clues for diagnosis., (Copyright © 2013 Elsevier Inc. All rights reserved.)

Published
2013
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13. A newly identified mutation in the complement factor I gene not associated with early post-transplant recurrence of atypical hemolytic-uremic syndrome: a case report.

Author

Ranghino A, Tognarelli G, Basso E, Messina M, Manzione AM, Daidola G, and Segoloni GP

Subjects
Adult, Atypical Hemolytic Uremic Syndrome, Humans, Male, Recurrence, Complement Factor I genetics, Hemolytic-Uremic Syndrome genetics, Kidney Transplantation, Mutation
Abstract

Atypical hemolytic uremic syndrome (aHUS), which can recur after renal transplantation, is associated with poor graft outcomes. The underlying genetic defect, namely, mutations in genes coding for the complement factor H, I (CFI), or membrane cofactor protein, greatly impacts the risk of aHUS recurrence. We report here the case of a patient with chronic renal failure due to aHUS in which screening for complement mutations, performed before wait-listing for kidney transplantation, showed a never described previously heterozygous mutation in the exon II of the CFI gene. Specifically, this mutation leads to a substitution of cytosine for guanosine at nucleotide 148, resulting in the change at amino acid 50 from arginine to proline. Subsequently, he received a renal allograft from deceased donor. Good graft function was established immediately, without clinical features of aHUS. Due to a lack of data on this mutation, we avoided prophylactic treatment for aHUS but closely monitored biochemical markers of aHUS to treat a possible recurrence. Immunosuppressive treatment was based on basiliximab, tacrolimus, steroids, and mycophenolic acid. At the time of discharge the serum creatinine was 1.4 mg/dL. Ten months after transplantation the patient is doing well without evidence of aHUS. Our case suggested that a heterozygous mutation in exon II of the CFI gene was not associated with a risk of early post-transplant aHUs recurrence adding new knowledge on complement mutations implicated in aHUS post-transplant recurrences., (Copyright © 2013 Elsevier Inc. All rights reserved.)

Published
2013
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14. Kidney biopsy in pregnancy: evidence for counselling? A systematic narrative review.

Author

Piccoli GB, Daidola G, Attini R, Parisi S, Fassio F, Naretto C, Deagostini MC, Castelluccia N, Ferraresi M, Roccatello D, and Todros T

Subjects
Biopsy adverse effects, Biopsy methods, Female, Humans, Pre-Eclampsia pathology, Pregnancy, Pregnancy Trimesters, Risk Assessment, Counseling, Kidney pathology, Kidney Diseases pathology, Pregnancy Complications pathology, Prenatal Diagnosis methods
Abstract

Background: Kidney diseases, which have a prevalence of 3% in women of childbearing age, are increasingly encountered in pregnancy. Glomerulonephritis may develop or flare up in pregnancy, and a differential diagnosis with pre-eclampsia may be impossible on clinical grounds. Use of kidney biopsy is controversial, but a systematic review has not been carried out to date., Objectives: To review the literature on kidney biopsy in pregnancy, with a focus on indications, risks and timing., Search Strategy: Medline, Embase, CHINAL and the Cochrane Library were searched in September 2012, with 'pregnancy' and 'kidney biopsy' used as MESH and free terms, for the period 1980-2012. Results were filtered for 'human' if this option was available., Selection Criteria: Biopsies during pregnancy and within 2 months after delivery. Case reports (fewer than five cases) and kidney grafts were excluded. Paper selection was performed in duplicate., Data Collection and Analysis: Data were extracted in duplicate. The high heterogeneity in study design necessitated that the review be narrative, except for data on adverse events, which were analysed with regard to the timing of kidney biopsy., Main Results: Of 949 references, 39 were selected, providing data on 243 biopsies in pregnancy and 1236 after delivery (timing was unclear in 106 women). The main aims of the studies were to define morphology in pre-eclampsia (23 studies), to carry out a risk-benefit analysis of kidney biopsy (11 studies), and to investigate pregnancy-related acute kidney injury (five studies). Four cases of major bleeding complications occurred at 23-26 weeks of gestation. Relevant complications were observed in 7% of women during pregnancy and 1% after delivery (P = 0.001). Kidney biopsy performed for the diagnosis of glomerulonephritis or pre-eclampsia led to therapeutic changes in 66% of cases., Authors' Conclusions: The evidence on kidney biopsy in pregnancy is heterogeneous, but a significantly higher risk of complications (relative to postpartum biopsy) was found, with a possible peak at around 25 gestational weeks., (© 2013 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2013 RCOG.)

Published
2013
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15. Excessive urinary tract dilatation and proteinuria in pregnancy: a common and overlooked association?

Author

Piccoli GB, Attini R, Parisi S, Vigotti FN, Daidola G, Deagostini MC, Ferraresi M, De Pascale A, Porpiglia F, Veltri A, and Todros T

Subjects
Adolescent, Adult, Comorbidity, Dilatation, Pathologic epidemiology, Female, Humans, Incidence, Italy epidemiology, Pregnancy, Risk Assessment, Young Adult, Pregnancy Complications epidemiology, Proteinuria epidemiology, Urinary Tract pathology, Urologic Diseases pathology
Abstract

Background: Proteinuria and dilatation of the urinary tract are both relatively common in pregnancy, the latter with a spectrum of symptoms, from none to severe pain and infection. Proteinuria is a rare occurrence in acute obstructive nephropathy; it has been reported in pregnancy, where it may pose a challenging differential diagnosis with pre-eclampsia.The aim of the present study is to report on the incidence of proteinuria (≥ 0.3; ≥ 0.5 g/day) in association with symptomatic-severe urinary tract dilatation in pregnancy., Methods: Case series., Setting: Nephrological-Obstetric Unit dedicated to pregnancy and kidney diseases (January 2000-April 2011)., Source: database prospectively updated since the start of the Unit. Retrospective review of clinical charts identified as relevant on the database, by a nephrologist and an obstetrician., Results: From January 2000 to April 2011, 262 pregnancies were referred. Urinary tract dilatation with or without infection was the main cause of referral in 26 cases (predominantly monolateral in 19 cases): 23 singletons, 1 lost to follow-up, 1 twin and 1 triplet. Patients were referred for urinary tract infection (15 cases) and/or renal pain (10 cases); 6 patients were treated by urologic interventions ("JJ" stenting). Among them, 11 singletons and 1 triple pregnancy developed proteinuria ≥ 0.3 g/day (46.1%). Proteinuria was ≥ 0.5 g/day in 6 singletons (23.1%). Proteinuria resolved after delivery in all cases. No patient developed hypertension; in none was an alternative cause of proteinuria evident. No significant demographic difference was observed in patients with renal dilatation who developed proteinuria versus those who did not. An association with the presence of "JJ" stenting was present (5/6 cases with proteinuria ≥ 0.5 g/day), which may reflect both severer obstruction and a role for vescico-ureteral reflux, induced by the stent., Conclusions: Symptomatic urinary tract dilatation may be associated with proteinuria in pregnancy. This association should be kept in mind in the differential diagnosis with other causes of proteinuria in pregnancy, including pre-eclampsia.

Published
2013
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16. Multiple pregnancies in CKD patients: an explosive mix.

Author

Piccoli GB, Arduino S, Attini R, Parisi S, Fassio F, Biolcati M, Pagano A, Bossotti C, Vasario E, Borgarello V, Daidola G, Ferraresi M, Gaglioti P, and Todros T

Subjects
Adult, Female, Humans, Hypertension, Pregnancy-Induced epidemiology, Italy epidemiology, Logistic Models, Multivariate Analysis, Pre-Eclampsia epidemiology, Pregnancy, Premature Birth epidemiology, Prevalence, Risk Factors, Pregnancy Complications epidemiology, Pregnancy Outcome epidemiology, Pregnancy, Multiple statistics & numerical data, Pregnancy, Twin statistics & numerical data, Renal Insufficiency, Chronic epidemiology
Abstract

Background and Objectives: CKD and multiple pregnancies bear important risks for pregnancy outcomes. The aim of the study was to define the risk for adverse pregnancy-related outcomes in multiple pregnancies in CKD patients in comparison with a control group of "low-risk" multiple pregnancies., Design, Setting, Participants, & Measurements: The study was performed in the Maternal Hospital of the University of Turin, Italy. Of 314 pregnancies referred in CKD (2000-2011), 20 were multiple (15 twin deliveries). Control groups consisted of 379 low-risk multiple pregnancies (314 twin deliveries) and 19 (15 twin deliveries) cases with hypertension-collagen diseases. Baseline data and outcomes were compared by univariate and logistic regression analyses., Results: The prevalence of multiple pregnancies was relatively high in the CKD population (6.4%); all referred cases were in early CKD stages (I-II); both creatinine (0.68 to 0.79 mg/dl; P=0.010) and proteinuria (0.81 to 3.42 g/d; P=0.041) significantly increased from referral to delivery. No significant difference in demographic data at baseline was found between cases and low-risk controls. CKD was associated with higher risk of adverse pregnancy outcomes versus low-risk twin pregnancies. Statistical significance was reached for preterm delivery (<34 weeks: 60% vs 26.4%; P=0.005; <32 weeks: 53.3% vs 12.7%; P<0.001), small for gestational age babies (28.6% vs 8.1%; P<0.001), need for Neonatal Intensive Care Unit (60% vs 12.7%; P<0.001), weight discordance between twins (40% vs 17.8%; P=0.032), and neonatal and perinatal mortality (6.6% vs 0.8%; P=0.032)., Conclusion: This study suggests that maternal-fetal risks are increased in multiple pregnancies in the early CKD stages.

Published
2013
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17. Pregnancy in CKD: whom should we follow and why?

Author

Piccoli GB, Fassio F, Attini R, Parisi S, Biolcati M, Ferraresi M, Pagano A, Daidola G, Deagostini MC, Gaglioti P, and Todros T

Subjects
Adult, Disease Progression, Female, Follow-Up Studies, Glomerular Filtration Rate, Humans, Italy epidemiology, Pregnancy, Pregnancy Outcome, Prevalence, Prospective Studies, Renal Dialysis, Renal Insufficiency, Chronic epidemiology, Risk Factors, Pregnancy Complications etiology, Pregnancy, High-Risk, Renal Insufficiency, Chronic complications
Abstract

Background: Chronic kidney disease (CKD) has a high prevalence in pregnancy. In a period of cost constraints, there is the need for identification of the risk pattern and for follow-up., Methods: Patients were staged according to K-DOQI guidelines. The analysis was prospective, January 2000-June 2011. Two hundred and forty-nine pregnancies were observed in 225 CKD patients; 176 singleton deliveries were recorded. The largest group encompasses stage 1 CKD patients, with normal renal function, in which 127 singleton deliveries were recorded. No hard outcomes occurred (death; dialysis); therefore, surrogate outcomes were analysed [caesarean section, prematurity, need for neonatal intensive care unit (NICU)]. Stage 1 patients were compared with normal controls (267 low-risk pregnancies followed in the same setting) and with patients with CKD stages 2-4 (49 singleton deliveries); two referral patterns were also analysed (known diagnoses; new diagnoses)., Results: The risk for adverse pregnancy rises significantly in stage 1 CKD, when compared with controls: odds ratios were caesarean section 2.73 (1.72-4.33); preterm delivery 8.50 (4.11-17.57); NICU 16.10 (4.42-58.66). The risks rise in later stages. There is a high prevalence of new CKD diagnosis (overall: 38.6%; stage 1: 43.3%); no significant outcome difference was found across the referral patterns. Hypertension and proteinuria are confirmed as independent risk factors., Conclusions: CKD is a risk factor in pregnancy; all patients should be followed within dedicated programmes from stage 1. There is need for dedicated interventions and educational programmes for maximizing the diagnostic and therapeutic potentials in early CKD stages.

Published
2012
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18. [Lymphomatous renal involvement].

Author

Besso L, Quercia AD, Daidola G, Burdese M, Colla L, Basso E, Karvela E, Marcuccio C, Tarella C, and Segoloni GP

Subjects
Glomerulonephritis etiology, Humans, Kidney Diseases etiology, Lymphoma complications
Abstract

The incidence of lymphomas, especially non-Hodgkin's lymphoma (NHL), has shown a steady increase over the last decades. At the same time, the prognosis has improved. Given the longer survival of lymphoma patients, pathological manifestations related to malignancy might become more frequent. In this setting, the kidney is one of the most important solid organs affected by direct or indirect lymphomatous involvement. Kidney involvement can be related to obstruction or treatment-induced toxicity, but more intriguing are 1) direct infiltration (NHL); 2) renal malignancies in patients affected by Hodgkin's disease or NHL; 3) associated glomerular diseases. Primary infiltration is rarely seen, while secondary infiltration is described most frequently in autopsy series, even in the absence of renal failure. These alterations may mimic glomerular and/or interstitial disease. The association with kidney malignancies, mostly renal cell carcinoma but also urothelial tumors in Hodgkin''s disease, is higher in lymphoma patients than in the general population: the relative risk at 10 years is about 1.5. Glomerulonephritis is described in patients with Hodgkin's disease or NHL; in the former minimal change disease is most frequent, in the latter the glomerular pattern varies widely. Glomerulonephritis can precede, be concurrent with, or follow lymphoma manifestations. Renal biopsy is often needed in this setting.

Published
2010

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