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185 results on '"G. Bellinghieri"'

2. Rene e Sport

Author

G. Bellinghieri, P. Monardo, and V. Savica

Subjects
Internal medicine, RC31-1245, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract non disponibile

Published
1993
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4. Restless Leg Syndrome Nel Paziente Uremico

Author

V. Savica, P. De Domenico, R. Musolino, R. Silvestri, C. Labate, and G. Bellinghieri

Subjects
Internal medicine, RC31-1245, Diseases of the genitourinary system. Urology, RC870-923
Abstract

Abstract non disponibile

Published
1991
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5. Clinical nephrology - miscellaneous

Author

C. Bantis, P. Heering, N.-M. Kouri, M. Siekierka-Harreis, M. Stangou, C. Schwandt, G. Efstratiadis, L.-C. Rump, K. Ivens, I. Haddiya, T. Houssaini Squalli, I. Laouad, B. Ramdani, R. Bayahia, G. G. Dimas, T. J. Tegos, S. G. Spiroglou, C. G. Pitsalidis, A. S. Sioulis, I. M. Karamouzis, C. G. Savopoulos, M. I. Karamouzis, A. G. Orologas, A. I. Hatzitolios, D. M. Grekas, D. Maixnerova, E. Jancova, I. Rychlik, R. Rysava, M. Merta, J. Reiterova, A. Kolsky, E. Honsova, J. Skibova, V. Tesar, Z. Kendi Celebi, R. Calayoglu, K. Keven, I. Kurultak, P. Mescigil, B. Erbay, O. Karatan, N. Duman, S. Erturk, G. Nergizoglu, S. Kutlay, S. Sengul, K. Ates, F. Marino, C. Martorano, M. Bellantoni, R. Tripepi, C. Zoccali, K. Ishizuka, Y. Harita, Y. Kajiho, H. Tsurumi, T. Asano, K. Nishiyama, N. Sugawara, H. Chikamoto, Y. Akioka, Y. Yamaguchi, T. Igarashi, M. Hattori, P. J. Heering, M. Sahay, D. V. Monova, S. V. Monov, Y.-y. Wang, H. Cheng, G.-q. Wang, H.-r. Dong, Y.-p. Chen, C.-j. Wang, Y.-l. Tang, E. Buti, E. Dervishi, F. Bergesio, G. Ghiandai, A. Mjeshtri, N. Paudice, A. L. Caldini, C. Nozzoli, E. E. Minetti, L. Sun, J. Feng, L. Yao, Q. Fan, J. Ma, L. Wang, T. Kirsanova, L. Merkusheva, N. Ruinihina, N. Kozlovskaya, G. Elenshleger, K. Turgutalp, U. Karabulut, T. Ozcan, I. Helvaci, A. Kiykim, A. Kaul, D. Bhadhuaria, R. sharma, N. Prasad, A. Gupta, C. Clajus, J. Schmidt, H. Haller, P. Kumpers, S. David, A. M. Sevillano, M. Molina, E. Gutierrez, E. Morales, E. Gonzalez, E. Hernandez, M. Praga, J. L. Conde Olasagasti, C. Vozmediano Poyatos, M. L. Illescas, S. Tallon, J. J. Uson Carrasco, A. Roca Munoz, F. Rivera Hernandez, G. Ismail, R. Jurubita, A. Andronesi, R. Bobeica, D. Zilisteanu, E. Rusu, C. Achim, A. Huerta, J. Caro, E. Gutierrez-Solis, A. Pasquariello, G. Pasquariello, M. Innocenti, G. Grassi, M. F. Egidi, O. Ozturk, A. Yildiz, C. B. Gul, K. Dilek, L. Tylicki, A. Jakubowska, E. Weber, S. Lizakowski, D. Swietlik, B. Rutkowski, A. Postorino, S. Costa, S. Cristadoro, G. Magazzu, G. Bellinghieri, V. Savica, M. Buemi, D. Santoro, Y. Lu, P. Shen, X. Li, Y. Xu, X. Pan, W. Wang, X. Chen, W. Zhang, H. Ren, N. Chen, B. P. Mitic, T. Cvetkovic, P. Vlahovic, R. Velickovic Radovanovic, V. Stefanovic, S. Kostic, V. Djordjevic, Q. Ao, Q. Ma, Q. Cheng, X. Wang, S. Liu, R. Zhang, S. Ozturk, S. Ozmen, D. Akin, R. Danis, M. Yilmaz, S. Hajri, S. Barbouche, H. Okpa, E. Oviasu, L. Ojogwu, N. Fotouhi, A. Ghaffari, F. Hamzavi, H. Nasri, M. Ardalan, A. Stott, A. Ullah, H. Anijeet, S. Ahmed, H. S. Kohli, R. Rajachandran, M. Rathi, V. Jha, V. Sakhuja, E. Yenigun, F. Dede, D. Turgut, E. Koc, H. Akoglu, S. Piskinpasa, R. Ozturk, A. Odabas, D. Bajcsi, G. Abraham, E. Kemeny, S. Sonkodi, P. Legrady, A. Letoha, K. Constantinou, Z. Ondrik, B. Ivanyi, G. Lucisano, N. Comi, P. Cianfrone, C. Summaria, V. Piraina, R. Talarico, C. Camastra, G. Fuiano, I. Proletov, E. Saganova, O. Galkina, E. Bogdanova, I. Zubina, V. Sipovskii, A. Smirnov, E. Bailly, D. Pierre, R. Kerdraon, O. Grezard, E. Gnappi, M. Delsante, M. Galetti, U. Maggiore, L. Manenti, M. J. Hasan, M. A. Muqueet, M. Mostafi, I. Chowdhury, W. Haque, T. Khan, Y.-J. Kang, E. J. Bae, H. S. Cho, S.-H. Chang, D. J. Park, G. Xu, H. Lin, Z. Hu, X. Yu, C. Xing, C. Mei, L. Zuo, Z. Ni, X. Ding, D. Li, Q. Zhang, X. Feng, and L. Lin

Subjects
Transplantation, medicine.medical_specialty, Nephrology, business.industry, medicine, Clinical nephrology, Intensive care medicine, business
Published
2013

6. Parathyroidectomy in Chronic Renal Failure: Short- and Long-Term Results on Parathyroid Function, Blood Pressure and Anemia

Author

F. Pecchini, M.G. Chiappini, Micaela Manni, G. Bellinghieri, Giorgio Coen, Santo Calabria, Franco Taggi, Daniela Sardella, M. DiLuca, F. Conte, A. Mallamace, C. Lagona, and Michele Ferrannini

Subjects
Male, Parathyroidectomy, medicine.medical_specialty, endocrine system diseases, Anemia, medicine.medical_treatment, Urology, Blood Pressure, Parathyroid Glands, Hemoglobins, Renal Dialysis, medicine, Humans, Dialysis, Aged, Retrospective Studies, Hyperparathyroidism, business.industry, Middle Aged, medicine.disease, Surgery, Blood pressure, Parathyroid Hormone, Kidney Failure, Chronic, Female, Hyperparathyroidism, Secondary, Secondary hyperparathyroidism, Hemodialysis, business, Kidney disease
Abstract

To evaluate the long-term results of parathyroidectomy (PTX) on parathyroid function, blood pressure and anemia, data of 45 patients with secondary Hyperparathyroidism in dialysis who had undergone PTX were collected retrospectively from 8 different dialysis units. The patients, 25 M and 20 F, mean age 56 ± 11 years, who were followed up for an average period of 3.3 ± 2.3 years, were divided into four groups according to the surgical procedure: 19 patients had had a subtotal PTX; 10 patients had undergone total PTX with autotransplantation (AT); 10 patients had had total PTX without AT, and 6 patients had undergone partial PTX. Taking a reduction in intact PTH >50% as sign of successful PTX, only 5 patients did not attain this result. Considering values of PTH between 20 and 200 pg/ml at the mid-term observation (1–2 years) as the optimal result, values under 20 pg/ml as an expression of permanent hypoparathyroidism, and those above 200 pg/ml as indicating persistent/recurrent hyperparathyroidism, 65.5% of patients operated with subtotal PTX and total PTX + AT had a therapeutic success, versus 31.2% of patients in the other two groups, due to excess permanent hypoparathyroidism and persistent/recurrent hyperparathyroidism; 20 of 45 patients with preoperative hypertension experienced a statistically and clinically significant decrease in blood pressure levels. An increase in serum hemoglobin was also observed, despite a reduction of administered erythropoietin. In conclusion, the results of PTX obtained from this multicenter study are comparable to those reported by single leading centers. Recommended surgical procedures are subtotal PTX and total PTX with AT. The fall in blood pressure in hypertensive patients is clinically significant, and improvement in anemia is also observed with a reduction in erythropoietin dosage.

Published
2001

7. Contents Vol. 79, 2007

Author

Carmen Pérez Romero, María del Puerto López del Amo González, Hamed Jalaeian, Zahran Budair, D.T. Consigliere, Yi Jun Shen, Isao Hara, Erkan Demir, Atsushi Takenaka, A. Blandino, Selahattin Bedir, P. Monardo, Hüseyin Aydemir, Yao Zhu, Takashi Tominaga, Selami Albayrak, Masato Fujisawa, Francesca Vichi, Erik Kouba, Toshifumi Kurahashi, Vedat Köksal, Francis Vacherot, Héctor Pastor-Navarro, Hideaki Miyake, Omer F. Karakas, Julio Escribano-Martínez, María J. Donate-Moreno, Yutaka Matsuyama, Manuel Atienzar-Tobarra, Toshiyuki Un-no, Kimio Fujita, Ali Thwaini, Miguel Segura-Martín, Xu Dong Yao, A.L. Morton, Mehdi Salehipour, T. Tony Cai, Iqbal S. Shergill, Yasuo Ohashi, Makoto Fujime, G. Bellinghieri, P.A. McArdle, Riccardo Bartoletti, H.H. Lim, J. Slade Hubbard, Kerem Inanoglu, D. Santoro, Selcuk Sahin, Bo Dai, Luca Cindolo, Volkan Tugcu, Francisco Sánchez-Sánchez, Eric Wallen, Fatih Zorluoglu, Onder Canguven, Cemal Göktaş, Hai Liang Zhang, Koray Erten, A. Magistro, José M. Giménez-Bachs, Ibrahim Hernández-Millán, K.K. Bhomi, Seijiro Honma, Mete Kilciler, Abdolaziz Khezri, Shi Lin Zhang, Clara Bermúdez-Tamayo, Shunsuke Nobata, Antonio Costanzi, Umberto Farina, Nader Tanideh, Stéphane Terry, F. Ciolino, Ahmet Fuat Peker, Antonio S. Salinas-Sánchez, H.Y. Tiong, Z. Hotiana, Ahmet Namık Kiper, Mohsen Kroup, Valiallah Azizi, Ding Wei Ye, Raj S. Pruthi, Fumitaka Shimizu, C.J. Adams, Wen Zhang, Alexandre de la Taille, José Jesús Martín Martín, Gianluca Giubilei, Seiichiro Ozono, Ali Ihsan Tasci, B. Cagla Ozbakis Akkurt, R.J.T. Alexander, Yılmaz Ordekci, V. Savica, Cenk Kilic, Ahmad Monabbati, Monica Cantile, Juan G. Lorenzo-Romero, Sadık Görür, Manit Arya, B. Vissamsetti, Hiroshi Sudoko, Yasar Candan, and Shinsuke Hayami

Subjects
Traditional medicine, business.industry, Urology, Medicine, business
Published
2007

9. Erectile dysfunction and quality of life in patients with chronic renal failure.]

Author

G, Bellinghieri, D, Santoro, E, Satta, and V, Savica

Subjects
Male, Erectile Dysfunction, Quality of Life, Humans, Kidney Failure, Chronic
Abstract

Erectile dysfunction (ED) is associated with a reduced quality of life; it represents a risk factor for the development of depression. ED may induce depression, loss of self-esteem, poor self-image, anxiety, and tension in the relationship with the partner. These emotional disturbances can create physical conditions that lead to increased difficulty in achieving an erection. Depression can deprive a person of the ability to experience many of life's pleasures. It not only affects the mind but also the body--often in unexpected ways. As a result, many men who have been diagnosed with depression find themselves suffering from another condition: ED. Sexual dysfunction is a big problem also in patients with chronic renal failure and seriously affects their quality of life. About 40% of men on dialysis suffer from ED. Many uremic patients have additional symptoms including reduction of libido and a decreased frequency of sexual intercourse. With the start of dialysis some of these symptoms may improve, without, however, returning to normal.

Published
2008

10. Seminal vesicle cysts with unilateral renal agenesis and contralateral ureteral stenosis in a beta-thalassemic patient: an unknown association by incomplete development of the mesonephric duct

Author

G. Bellinghieri, A. Magistro, Domenico Santoro, A. Blandino, Paolo Monardo, F. Ciolino, and Vincenzo Savica

Subjects
Male, medicine.medical_specialty, Unilateral renal agenesis, Adolescent, Urology, Ureteral stenosis, Kidney, Mesonephric duct, Seminal vesicle, Medicine, Humans, Abnormalities, Multiple, medicine.diagnostic_test, business.industry, Cysts, Ultrasound, beta-Thalassemia, Seminal Vesicles, Magnetic resonance imaging, Ultrasonography, Doppler, Urography, Anatomy, Wolffian Ducts, Magnetic Resonance Imaging, medicine.anatomical_structure, Urogenital Abnormalities, Abdomen, Laparoscopy, business, Tomography, X-Ray Computed, Follow-Up Studies, Ureteral Obstruction
Abstract

We report the case of a 13-year-old male patient with β-thalassemic trait who presented for a colic pain. An ultrasound of the abdomen revealed absence of the right kidney with a complex hypoechogenic pelvic mass causing mild pressure on the posterior bladder wall. Urography showed hypertrophy of the left kidney with moderate ureteral enlargement of the distal third due to an insertion defect in the bladder suggestive of a primary segmental nonobstructing megaureter. MR studies showed right multilocular seminal vesicle cysts. One year later an MR examination of the pelvis showed an increase in size of seminal vesicle cysts and open surgery was performed to remove the cystic retrovesical mass. Our case represents a very rare association of seminal vesicle cysts, unilateral renal agenesis and alteration in contralateral ureteral insertion in a patient with β-thalassemic trait.

Published
2005

11. Twice versus thrice weekly administration of intravenous calcitriol in dialysis patients: a randomized prospective trial. Gruppo Italiano di Studio dell'Osteodistrofia Renale

Author

M, Gallieni, D, Brancaccio, F, Antonucci, G, Bellinghieri, P, Carpani, M, Cozzolino, F, D'Agostino, G, Del Mastro, A, Mallamace, B, Memoli, Gallieni, M, Brancaccio, D, Antonucci, F, Bellinghieri, G, Carpani, P, Cozzolino, M, D'Agostino, F, Del Mastro, G, Mallamace, A, and Memoli, Bruno

Subjects
Adult, Aged, 80 and over, Chronic Kidney Disease-Mineral and Bone Disorder, Male, Calcium Channel Agonists, Calcitriol, Renal Dialysis, Humans, Female, Prospective Studies, Middle Aged, Drug Administration Schedule, Aged
Abstract

Administration of intravenous (i.v.) calcitriol three times weekly effectively controls the synthesis and secretion of PTH in most uremic patients. Administration of a single dose of 1.25(OH)2D3 reduces synthesis of PTH-mRNA for 6 days in rats. Moreover, it can lower PTH levels for up to 4 days in chronic hemodialysis patients. Therefore, a good response to the administration of i.v. calcitriol two times weekly can be expected. We studied - in a multicenter randomized study in patients with moderate to severe secondary hyperparathyroidism - the effects of the same doses of intravenous calcitriol, administered two or three times weekly.Twenty-two hemodialysis patients were randomized into two frequencies of treatment groups: two times (G-2/w) and three times weekly (G-3/w). Both groups were treated with increasing doses of intravenous calcitriol for 3 months (first month 3 microg, second month 4 microg, third month 6 microg weekly).After 12 weeks of therapy with intravenous calcitriol the G-2/w group showed a significant reduction in serum PTH levels (from 821 +/- 392 to 350 +/- 246 pg/ml; mean reduction = 57.4%) comparable to the decrease observed in the G-3/w group (from 632 +/- 116 to 246 +/- 190 pg/ml; mean reduction = 61.2%). Ionized calcium (G-2/w from 1.13 +/-0.10 to 1.14 +/- 0.08 and G-3/w 1.21 +/- 0.13 to 1.26 +/- 0.18 mmol/l) and phosphate levels (G-2/w from 4.99 +/- 1.01 to 5.99 +/- 1.78 and G-3/w 5.31 +/- 0.73 to 5.81 +/- 1.18 mg/dl) did not change significantly and phosphate binders were not modified during the study.This study confirms that intravenous calcitriol is an effective therapy for moderate to severe secondary hyperparathyroidism. The administration of two doses per week of intravenous calcitriol is as efficacious as three doses per week in suppressing PTH secretion.

Published
2000

12. Subject Index Vol. 79, 2007

Author

K.K. Bhomi, Bo Dai, A. Blandino, Cemal Göktaş, Francesca Vichi, F. Ciolino, Francis Vacherot, Manit Arya, Valiallah Azizi, Ali Thwaini, A.L. Morton, Omer F. Karakas, Mehdi Salehipour, P.A. McArdle, Riccardo Bartoletti, J. Slade Hubbard, Isao Hara, Ding Wei Ye, Volkan Tugcu, Iqbal S. Shergill, Kerem Inanoglu, Erkan Demir, Selcuk Sahin, Selahattin Bedir, Antonio S. Salinas-Sánchez, Sadık Görür, D. Santoro, Masato Fujisawa, José M. Giménez-Bachs, Erik Kouba, Carmen Pérez Romero, Toshifumi Kurahashi, Yasar Candan, Shunsuke Nobata, Z. Hotiana, Ahmet Namık Kiper, G. Bellinghieri, Shi Lin Zhang, H.H. Lim, Seiichiro Ozono, María J. Donate-Moreno, Selami Albayrak, Shinsuke Hayami, Yutaka Matsuyama, Luca Cindolo, Vedat Köksal, Miguel Segura-Martín, Ali Ihsan Tasci, María del Puerto López del Amo González, Francisco Sánchez-Sánchez, Hideaki Miyake, Umberto Farina, Yi Jun Shen, Onder Canguven, Yılmaz Ordekci, Clara Bermúdez-Tamayo, Héctor Pastor-Navarro, Mohsen Kroup, B. Cagla Ozbakis Akkurt, Toshiyuki Un-no, Kimio Fujita, Atsushi Takenaka, Fatih Zorluoglu, R.J.T. Alexander, Ibrahim Hernández-Millán, Takashi Tominaga, Raj S. Pruthi, Gianluca Giubilei, Abdolaziz Khezri, José Jesús Martín Martín, Monica Cantile, Nader Tanideh, V. Savica, C.J. Adams, Eric Wallen, Hai Liang Zhang, Koray Erten, Cenk Kilic, Xu Dong Yao, Ahmad Monabbati, Seijiro Honma, Stéphane Terry, Hamed Jalaeian, Zahran Budair, Hüseyin Aydemir, Yao Zhu, Yasuo Ohashi, Makoto Fujime, Alexandre de la Taille, Manuel Atienzar-Tobarra, Fumitaka Shimizu, D.T. Consigliere, Julio Escribano-Martínez, Wen Zhang, A. Magistro, Mete Kilciler, Antonio Costanzi, Ahmet Fuat Peker, H.Y. Tiong, P. Monardo, Juan G. Lorenzo-Romero, B. Vissamsetti, Hiroshi Sudoko, and T. Tony Cai

Subjects
Index (economics), business.industry, Urology, Statistics, Medicine, Subject (documents), business
Published
2007

13. Carnitine and lipid profile in uremia

Author

V, Savica and G, Bellinghieri

Subjects
Lipoproteins, LDL, Male, Renal Dialysis, Carnitine, Lipoproteins, Humans, Female, Lipoproteins, HDL, Uremia
Abstract

Several authors have supplemented patients submitted to the hemodialytic treatment with L-carnitine, with the aim to affect the lipid profile often unfavourably altered in these patients. Different doses of the compound have been employed and the outcome in plasma lipid changes is very dissimilar. Some authors have reported favourable changes, some have not observed any effect, some have reported a worsening of the lipids profile. A review of the data so far available may allow some considerations on the suitability of using L-carnitine in order to affect favourably the progress of accelerated atherosclerosis.

Published
1997

14. Uremic autonomic neuropathy: recovery following bicarbonate hemodialysis

Author

G, Vita, V, Savica, S, Milone, A, Trusso, G, Bellinghieri, and C, Messina

Subjects
Adult, Male, Time Factors, Bayes Theorem, Acetates, Middle Aged, Hemodialysis Solutions, Bicarbonates, Autonomic Nervous System Diseases, Renal Dialysis, Multivariate Analysis, Humans, Female, Hypoxia, Aged, Follow-Up Studies, Uremia
Abstract

Autonomic function was followed in 8 chronic uremic patients on periodic hemodialysis over a period of almost eight years. The cardiovascular autonomic testing included R-R interval variation test, deep breathing, Valsalva manoeuvre, heart rate and blood pressure responses to standing, sustained handgrip. The patients were investigated on entry into the study and after 18, 56, and 92 months. Six months after the study at time 56 months, they switched from acetate to bicarbonate dialysis. The response to deep breathing test was significantly reduced at time 18 months versus baseline (P = 0.014), but significantly increased at time 92 months versus 56 months (P = 0.042). A significant decrease was found in the systolic blood pressure response to standing between baseline and 18 months (P = 0.014) and in the response to handgrip test between 18 and 56 months (P = 0.014). Multivariate analysis of the autonomic tests by a pattern recognition method (Bayesian analysis) showed that, at the time of entry into the study, two out of eight patients had autonomic damage. At 18 and 56 months, 6/8 patients had autonomic dysfunction. At the last time of investigation, 30 months after the onset of bicarbonate dialysis, all the patients showed a reversal of autonomic damage. Age and duration of dialysis on entry did not affect autonomic function. The present study is the first demonstration that autonomic neuropathy can recover after long-term dialysis. Since chronic hypoxemia is a cause of polyneuropathy, we postulate that: 1) hypoxemia in dialysis patients may have a role in the pathogenesis of uremic polyneuropathy, and particularly of autonomic dysfunction; 2) in patients on bicarbonate dialysis, a greater hemodynamic stability with less hypoxemia may lead to a recovery of autonomic function.

Published
1996

15. [Blood aluminum in a population of hemodialyzed patients. 1981-1991: a comparison of a decade]

Author

V, Savica, R, Musolino, A, Mallamace, B, Ricciardi, F, Torre, G, Costantino, and G, Bellinghieri

Subjects
Male, Renal Dialysis, Humans, Female, Middle Aged, Aged, Aluminum, Retrospective Studies
Abstract

The authors report their data on the behaviour of serum aluminium registered at a 10 year interval among a population of haemodialyzed patients. Improved knowledge of the toxic role of aluminium and of the sources of pollution in dialyzed patients seems to relegate the neurologic toxicity of aluminium to a historical aspect.

Published
1994

16. Extracorporeal dialysis: techniques and adequacy

Author

C. Donadio, A. Kanaki, A. Martin-Gomez, S. Garcia, M. Palacios-Gomez, D. Calia, E. Colombini, F. DI Francesco, S. Ghimenti, M. Onor, D. Tognotti, R. Fuoco, E. Marka-Castro, M. I. Torres Zamora, J. Giron-Mino, M. A. Jaime-Solis, L. M. Arteaga, H. Romero, A. Akonur, K. Leypoldt, M. Asola, B. Culleton, S. Eloot, G. Glorieux, N. Nathalie, R. Vanholder, A. Perez de Jose, U. Verdalles Guzman, S. Abad Esttebanez, A. Vega Martinez, D. Barraca, C. Yuste, L. Bucalo, A. Rincon, J. M. Lopez-Gomez, P. Bataille, P. Celine, A. Raymond, G. Francois, L. Herve, D. Michel, R. Jean Louis, F. Zhu, P. Kotanko, S. Thijssen, N. W. Levin, N. Papamichail, M. Bougiakli, C. Gouva, S. Antoniou, S. Gianitsi, A. Vlachopanou, S. Chachalos, K. Naka, D. Kaarsavvidou, K. Katopodis, L. Michalis, K. Sasaki, K. Yasuda, M. Yamato, A. Surace, P. Rovatti, D. Steckiph, R. Bandini, S. Severi, A. Dellacasa Bellingegni, A. Santoro, M. Arias, A. Sentis, N. Perez, N. Fontsere, M. Vera, N. Rodriguez, C. Arcal, N. Ortega, F. Uriza, A. Cases, F. Maduell, S. R. Abbas, P. Georgianos, P. Sarafidis, P. Nikolaidis, A. Lasaridis, A. Ahmed, H. Kaoutar, B. Mohammed, O. Zouhir, P. Balter, N. Ginsberg, P. Taylor, T. Sullivan, L. A. Usvyat, P. Zabetakis, U. Moissl, M. Ferrario, F. Garzotto, P. Wabel, D. Cruz, C. Tetta, M. G. Signorini, S. Cerutti, A. Brendolan, C. Ronco, J. Heaf, M. Axelsen, R. S. Pedersen, H. Amine, Z. Oualim, A. L. Ammirati, N. K. Guimaraes de Souza, T. Nemoto Matsui, M. Luiz Vieira, W. A. Alves de Oliveira, C. H. Fischer, F. Dias Carneiro, I. J. Iizuka, M. Aparecida de Souza, A. C. Mallet, M. C. Cruz Andreoli, B. F. Cardoso Dos Santos, L. Rosales, Y. Dou, M. Carter, A. Testa, L. Sottini, B. Giacon, E. Prati, C. Loschiavo, M. Brognoli, C. Marseglia, A. Tommasi, L. Sereni, G. Palladino, S. Bove, G. Bosticardo, E. Schillaci, P. Detoma, R. Bergia, J. W. Park, S. J. Moon, H. Y. Choi, S. K. Ha, H.-C. Park, Y. Liao, L. Zhang, P. Fu, H. Igarashi, N. Suzuki, S. Esashi, I. Masakane, V. Panichi, G. De Ferrari, S. Saffiotti, A. Sidoti, M. Biagioli, S. Bianchi, P. Imperiali, C. Gabrielli, P. Conti, P. Patrone, G. Rombola, V. Falqui, C. Mura, A. Icardi, A. Rosati, F. Santori, A. Mannarino, A. Bertucci, J. Jeong, O. K. Kim, N. H. Kim, M. Bots, C. Den Hoedt, M. P. Grooteman, N. C. Van der Weerd, A. H. A. Mazairac, R. Levesque, P. M. Ter Wee, M. J. Nube, P. Blankestijn, M. A. Van den Dorpel, Y. Park, J. Jeon, N. Tessitore, V. Bedogna, D. Girelli, L. Corazza, P. Jacky, Q. Guillaume, B. Julien, W. Marcinkowski, M. Drozdz, A. Milkowski, T. Rydzynska, T. Prystacki, R. August, E. Benedyk-Lorens, K. Bladek, J. Cina, G. Janiszewska, A. Kaczmarek, T. Lewinska, M. Mendel, M. Paszkot, E. Trafidlo, M. Trzciniecka-Kloczkowska, A. Vasilevsky, G. Konoplev, O. Lopatenko, A. Komashnya, K. Visnevsky, R. Gerasimchuk, I. Neivelt, A. Frorip, M. Vostry, J. Racek, D. Rajdl, J. Eiselt, L. Malanova, U. Pechter, A. Selart, M. Ots-Rosenberg, D. H. Krieter, S. Seidel, K. Merget, H.-D. Lemke, C. Wanner, B. Canaud, A. Rodriguez, A. Morgenroth, K. Von Appen, G.-P. Dragoun, R. Fluck, D. Fouque, R. Lockridge, Y. Motomiya, Y. Uji, T. Hiramatsu, Y. Ando, M. Furuta, T. Kuragano, A. Kida, M. Yahiro, Y. Otaki, Y. Hasuike, H. Nonoguchi, T. Nakanishi, M. Sain, V. Kovacic, D. Ljutic, J. Radic, I. Jelicic, S. F. Yalin, S. Trabulus, A. S. Yalin, M. R. Altiparmak, K. Serdengecti, A. Ohtsuka, K. Fukami, K. Ishikawa, R. Ando, Y. Kaida, T. Adachi, K. Sugi, S. Okuda, O. B. Nesterova, E. D. Suglobova, R. V. Golubev, A. N. Vasiliev, V. A. Lazeba, A. V. Smirnov, K. Arita, E. Kihara, K. Maeda, H. Oda, S. Doi, T. Masaki, S. Hidaka, K. Ishioka, M. Oka, H. Moriya, T. Ohtake, S. Nomura, S. Kobayashi, S. Wagner, A. Gmerek, J. Wagner, V. Wizemann, N. Eftimovska - Otovic, K. Spaseska-Gjurovska, S. Bogdanovska, E. Babalj - Banskolieva, M. Milovanceva, R. Grozdanovski, A. Pisani, E. Riccio, A. Mancini, P. Ambuhl, S. Astrid, P. Ivana, H. Martin, K. Thomas, R. Hans-Rudolf, A. Daniel, K. Denes, M. Marco, R. P. Wuthrich, S. Andreas, S. Andrulli, P. Altieri, G. Sau, P. Bolasco, L. A. Pedrini, C. Basile, S. David, M. Feriani, P. E. Nebiolo, R. Ferrara, D. Casu, F. Logias, R. Tarchini, F. Cadinu, M. Passaghe, G. Fundoni, G. Villa, B. R. DI Iorio, C. Zoccali, F. Locatelli, M. Hamamoto, D.-Y. Lee, B. Kim, K. H. Moon, Z. LI, P. Ahrenholz, R. E. Winkler, G. Waitz, H. Wolf, G. Grundstrom, M. Alquist, M. Holmquist, A. Christensson, P. Bjork, M. Abdgawad, L. Ekholm, M. Segelmark, C. Corsi, J. De Bie, E. Mambelli, D. Mortara, D. Arroyo, N. Panizo, B. Quiroga, J. Reque, R. Melero, M. Rodriguez-Ferrero, P. Rodriguez-Benitez, F. Anaya, J. Luno, A. Ragon, A. James, P. Brunet, S. Ribeiro, M. S. Faria, S. Rocha, S. Rodrigues, C. Catarino, F. Reis, H. Nascimento, J. Fernandes, V. Miranda, A. Quintanilha, L. Belo, E. Costa, A. Santos-Silva, J. Arund, R. Tanner, I. Fridolin, M. Luman, C. Clajus, J. T. Kielstein, H. Haller, P. Libutti, P. Lisi, L. Vernaglione, F. Casucci, N. Losurdo, A. Teutonico, C. Lomonte, C. Krisp, D. A. Wolters, M. Matsuyama, T. Tomo, K. Ishida, K. Matsuyama, T. Nakata, J. Kadota, M. Caiazzo, E. Monari, A. Cuoghi, E. Bellei, S. Bergamini, A. Tomasi, T. Baranger, P. Seniuta, F. Berge, V. Drouillat, C. Frangie, E. Rosier, W. Labonia, A. Lescano, D. Rubio, N. Von der Lippe, J. A. Jorgensen, T. B. Osthus, B. Waldum, I. Os, M. Bossola, E. DI Stasio, M. Antocicco, L. Tazza, I. Griveas, A. Karameris, P. Pasadakis, V. Savica, D. Santoro, S. Saitta, V. Tigano, G. Bellinghieri, S. Gangemi, R. Daniela, I. A. Checherita, A. Ciocalteu, I. A. Vacaroiu, A. Niculae, E. Stefaniak, I. Pietrzak, D. Krupa, L. Garred, E. Mancini, L. Corrazza, M. Atti, B. Afsar, D. Stamopoulos, N. Mpakirtzi, B. Gogola, M. Zeibekis, D. Stivarou, M. Panagiotou, E. Grapsa, O. Vega Vega, D. Barraca Nunez, M. Fernandez-Lucas, A. Gomis, J. L. Teruel, S. Elias, C. Quereda, L. Hignell, S. Humphrey, N. Pacy, and N. Afentakis

Subjects
Transplantation, medicine.medical_specialty, Extracorporeal Dialysis, Nephrology, business.industry, Uremic toxins, Medicine, Identification (biology), business, Intensive care medicine, Microbiology
Published
2011

17. Protein-energy wasting, inflammation and oxidative stress in CKD 5D

Author

L. Rosales, O. Vega, L. Usvyat, S. Thijssen, N. Levin, P. Kotanko, T. Miyamoto, A. Witasp, A. Rashid Qureshi, O. Heimburger, P. Barany, L. Nordfors, B. Lindholm, P. Stenvinkel, J. Jesus Carrero, M. Kalousova, H. Benakova, A. A. Kubena, S. Dusilova-Sulkova, V. Tesar, T. Zima, Y. J. Lee, M. S. Kim, B. G. Song, S. Cho, S. R. Kim, M. Stockler-Pinto, J. Lobo, C. Moraes, A. Barros, N. Farage, G. Boaventura, D. Mafra, O. Malm, S. Matsuda, N. Akaike, K. Kajiwara, D. Tovbin, S. Kesari, D. Sola-Del Valle, J. Barasch, A. Douvdevani, M. Zlotnik, A. Abd Elkadir, S. Storch, M. Sarikaya, F. Sari, J. Gunes, M. Eren, R. Cetinkaya, J.-C. Hwang, T.-L. Ma, C.-T. Wang, H. Ogawa, T. Nagaya, Y. Ota, M. Sarai, O. Oda, B. Biavo, C. Uezima, M. E. Costa, C. Barros, J. P. Martins, E. Ribeiro Jr, C. Tzanno-Martins, H. Honda, N. Kimata, K. Wakai, T. Akizawa, J. Droulias, V. Filliponi, C. Argyropoulos, R. Fischer, C. Papakonstantinou, C. Papadopoulos, A. Kouvelis, G. Zervas, E. Dampolia, N. Zerefos, D. Valis, C. Sarcina, I. Baragetti, P. Uboldi, L. Buzzi, K. Garlaschelli, F. Ferrario, V. Terraneo, G. D. Norata, A. L. Catapano, C. Pozzi, G. Conti, D. Santoro, D. Caccamo, S. Condello, D. Pazzano, V. Savica, R. Jentile, C. Fede, G. Bellinghieri, R. Zortcheva, V. Ikonomov, B. Galunska, D. Paskalev, D. Dobreva, D. Ivanova, M. Tsunoda, R. Ikee, N. Sasaki, N. Sato, N. Hashimoto, L. Korol, I. Dudar, L. Migal, Y. Gonchar, I. Seleznova, V. Ischenko, M. Erkmen Uyar, E. Tutal, Z. Bal, N. Ahmed, S. Sezer, D. Fedak, M. Kuzniewski, D. Pawlica, B. Kusnierz-Cabala, B. Solnica, M. Drozdz, K. Janda, W. Sulowicz, J. Kopec, M. Banach, and V. Leal

Subjects
Transplantation, medicine.medical_specialty, Endocrinology, Nephrology, business.industry, Internal medicine, medicine, Inflammation, Protein energy wasting, medicine.symptom, medicine.disease_cause, business, Oxidative stress
Published
2011

18. The coagulative system in haemodialyzed patients: the relationship between the elderly and hypertrygliceridaemia

Author

V, Savica, G, Bellinghieri, C M, Barbera, M, Egitto, and F, Consolo

Subjects
Hypertriglyceridemia, Epinephrine, Platelet Aggregation, Arteriosclerosis, Age Factors, Thrombin, Blood Coagulation Disorders, Middle Aged, beta-Thromboglobulin, Adenosine Diphosphate, Renal Dialysis, Humans, Collagen, Aged, Fibrinopeptide A, Uremia
Abstract

The coagulative system has an important role on haemodialysis and on atherosclerosis genesis; in particular the platelets are key elements of the coagulation and of atherosclerosis phenomena. Alterations of the coagulative system and increase risk of developing atherosclerosis are reported in the aging. We in this paper, report the results obtained studying the influence of the interaction between the elderly and dyslipidemia on the coagulative system in haemodialyzed patients. The obtained data showed that the hypertriglyceridaemia in interaction with the elderly accelerates and increases platelet aggregation after stimulation by ADP, Epinephrine and Collagen. So, it is important to consider hypertriglyceridaemia and age as thrombogenic factors and atherosclerosis accelerating factors in haemodialyzed patients.

Published
1992

19. [Dyslipidemia in the uremic patient: the therapeutic role played by simvastatin]

Author

G, Bellinghieri, B, Angelé, and V, Savica

Subjects
Hypertriglyceridemia, Male, Simvastatin, Anticholesteremic Agents, Hyperlipidemias, Middle Aged, Combined Modality Therapy, Renal Dialysis, Drug Evaluation, Humans, Kidney Failure, Chronic, Female, Lovastatin, Aged, Uremia
Abstract

Simvastatin is a pharmacological molecule belonging to the family of HMG-CoA reductase inhibitors, recently included in plasma cholesterol lowering therapy. The authors carried out a study on the possible triglyceride lowering activity of simvastatin in dialyzed patients with chronic uremia considering its particular mechanism of action. The subjects selected for the study were suffering from uremia either complied with dosage prescribed or not. The obtained data showed the substance's triglyceride lowering effect, but no simvastatin-related side effect in the dialysed patients with uremia. For these reasons and for the substance's well-known cholesterol-lowering effect, simvastatin seems to deserve the definition of choice drug in the treatment of altered lipidemia in patients with uremia.

Published
1992

20. [The hypotriglyceridemic action of the combination of L-carnitine + simvastatin vs. L-carnitine and vs. simvastatin]

Author

V, Savica, G, Bellinghieri, and F, Lamanna

Subjects
Hypertriglyceridemia, Male, Simvastatin, Anticholesteremic Agents, Middle Aged, Combined Modality Therapy, Renal Dialysis, Carnitine, Drug Evaluation, Humans, Kidney Failure, Chronic, Drug Therapy, Combination, Female, Lovastatin, Aged
Abstract

Previous studies had determined the role played by L-carnitine and simvastatin in the treatment of altered lipidemia in dialyzed patients with chronic uremia. The authors carried out a study on the above substances either singly or together administered to the same patients with chronic uremia in hemodialysis. This study was aimed at demonstrating the possible synergic normolipidemic action of both substances in comparison with their single administration, because their different mechanism of action could be metabolically enhanced. The obtained results demonstrated that the therapeutic association proposed is preferable to the use of the single substances. Moreover, a higher and more rapid normolipidemic effect was obtained after using L-carnitina associated with simvastatin with respect to the separated substances.

Published
1992

21. Uremic autonomic dysfunction evaluated by pattern recognition analysis

Author

G, Vita, P, Princi, V, Savica, G, Bellinghieri, R M, Puglisi, L, Marabello, and C, Messina

Subjects
Male, Autonomic Nervous System Diseases, Reflex, Humans, Computer Simulation, Female, Diagnosis, Computer-Assisted, Middle Aged, Sensitivity and Specificity, Pattern Recognition, Automated, Uremia
Abstract

A pattern recognition analysis of six cardiovascular reflex tests was performed with the aim to increase their diagnostic efficiency. A normal model was defined by SIMCA method using log-transformed values of 85 healthy subjects. The model was tested with data from 60 patients with chronic renal failure. Specificity resulted 94% and sensitivity 96%. 55% of the uremics were recognized affected by autonomic damage. The method allowed a better definition of autonomic function in those patients defined as "borderline" on conventional evaluation of the tests. Pattern recognition analysis of autonomic tests provides a global assessment of all the tests performed. Its use should be encouraged as a diagnostic tool.

Published
1991

22. Perdite Ematiche Nel Circuito Extracorporeo

Author

V. Savica and G. Bellinghieri

Subjects
lcsh:Internal medicine, business.industry, Medicine, General Medicine, business, lcsh:RC31-1245, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923
Abstract

non disponibile

Published
1991

23. L-carnitine and platelet aggregation in uremic patients subjected to hemodialysis

Author

G, Bellinghieri, V, Savica, C M, Barbera, B, Ricciardi, M, Egitto, F, Torre, G, Valentini, S, D'Iddio, E, Bagiella, and A, Mallamace

Subjects
Adult, Male, Platelet Aggregation, Middle Aged, beta-Thromboglobulin, Lipids, Double-Blind Method, Renal Dialysis, Carnitine, Thromboembolism, Humans, Female, Randomized Controlled Trials as Topic, Uremia
Abstract

It has been reported that treatment with L-carnitine at a daily dose of 3 g orally may cause a rise in platelet aggregation and serum triglyceride concentration in hemodialyzed patients. The present double-blind cross-over study has been performed to evaluate the influence of L-carnitine when compared with placebo on platelet aggregation and plasma concentrations of various factors involved in platelet activation. In addition, the concentration of triglycerides, cholesterol and HDL-cholesterol has been evaluated. 18 uremic patients on maintenance hemodialysis for at least 1 year were randomly allocated either to a control group receiving placebo or to a group treated with L-carnitine. Statistical analysis performed by means of ANOVA did not show any significant change in the serum concentration of cholesterol, HDL-cholesterol and triglycerides. Furthermore, platelet aggregation tests (performed with adenosine 5'-diphosphate, epinephrine, thrombin and collagen) and plasma beta-thromboglobulin concentration did not show any statistically significant difference. In addition, the plasma concentration of several coagulation markers, such as factor VIIIc, antithrombin III, alpha 2-antiplasmin, and fibrinopeptide A, did not show any significant variation. The results suggest that under our experimental conditions L-carnitine neither increases the risk of thromboembolism nor alters the serum lipid content in uremic patients on chronic hemodialysis.

Published
1990

24. Contents, Vol. 28, 1988

Author

S. Gentile, Teresa Alonso-Marné, Apolinar Rodriguez-Albariño, C. Venuto, R. Mutani, G. Fritsch, G.G. Brune, J.M. Leger, M. Lukić, H.-P. Schlake, J.J.M. Askenasy, Pablo Barreiro-Tella, R. Dattola, G. Schneider, Ferdinando Maggioni, R. Calabrò, Gianfranco Denes, M. Gianelli, Exuperio Díez-Tejedor, P. Castaigne, G. Bellinghieri, R. Giordano, Vladimir S. Kostic, H.P. Cathala, Jack Ten Ten Holter, A.C. Ludolph, Marija Mostarica-Stojkovic, Zorica Ramić, M. Baruchello, U. Dimanico, A. Toscano, P. Bouche, Federico Micheli, Cees Tijssen, L. Manna, K.-H. Grotemeyer, Miroslav Kovăcević, I.W. Husstedt, Sergio E. Starkstein, Lisa Cipolotti, G. Vita, Giorgio Zanchin, Guillermo Amer-Ferrer, F. Ebner, Raffaele De Caro, F. Monaco, Antonia Gallo, Ignacio Casas Parera, Luciano De Zanche, V. Savica, Ana Frank, Patrizia Bisiacchi, P. Brune, Martín Nogues, L. Verzè, and F. Lafont

Subjects
Neurology, Neurology (clinical)
Published
1988

25. Subject Index Vol. 28, 1988

Author

G. Bellinghieri, Guillermo Amer-Ferrer, R. Giordano, Vladimir S. Kostic, Marija Mostarica-Stojković, P. Castaigne, Apolinar Rodriguez-Albariño, L. Verzè, G. Schneider, Exuperio Díez-Tejedor, S. Gentile, J.M. Leger, Pablo Barreiro-Tella, R. Dattola, Jack Ten Ten Holter, M. Baruchello, M. Gianelli, P. Brune, U. Dimanico, A.C. Ludolph, Luciano De Zanche, Antonia Gallo, V. Savica, K.-H. Grotemeyer, Zorica Ramić, G.G. Brune, F. Lafont, P. Bouche, Sergio E. Starkstein, Federico Micheli, H.-P. Schlake, L. Manna, I.W. Husstedt, F. Ebner, A. Toscano, Martín Nogues, J.J.M. Askenasy, Giorgio Zanchin, Raffaele De Caro, G. Vita, Cees Tijssen, Teresa Alonso-Marné, Ignacio Casas Parera, R. Calabrò, Ferdinando Maggioni, M. Lukić, H.P. Cathala, Gianfranco Denes, C. Venuto, R. Mutani, G. Fritsch, Miroslav Kovăcević, Lisa Cipolotti, F. Monaco, Ana Frank, and Patrizia Bisiacchi

Subjects
Index (economics), Neurology, Statistics, Subject (documents), Neurology (clinical), Mathematics
Published
1988

27. Age-dependent occurrence of autonomic dysfunction in chronic uraemia

Author

G, Vita, V, Savica, L, Marabello, R M, Puglisi, S, Serra, R, Musolino, G, Bellinghieri, and C, Messina

Subjects
Adult, Aging, Sympathetic Nervous System, Parasympathetic Nervous System, Renal Dialysis, Chronic Disease, Humans, Kidney Failure, Chronic, Regression Analysis, Middle Aged, Autonomic Nervous System, Aged, Uremia
Abstract

A battery of cardiovascular reflex tests were performed in twenty patients with chronic renal failure on intermittent haemodialysis. Using age-adjusted confidence limits, old-aged uraemics showed more extensive parasympathetic and sympathetic dysfunction than middle-aged patients. The results suggest that autonomic nervous system in the elderly is more susceptible to uraemic toxins than in the middle age. This should lead to better preventive and therapeutic strategies in older uraemics.

Published
1987

30. [Glucagon and renal function]

Author

G, Squadrito, D, Ceruso, N, Frisina, L, D'Andrea-Petrelli, and G, Bellinghieri

Subjects
Adult, Heart Failure, Natriuresis, Middle Aged, Water-Electrolyte Balance, Glucagon, Kidney, Kidney Function Tests, Diuresis, Chlorides, Creatinine, Potassium, Humans, Urea, Calcium, Aged
Published
1973

32. Trichomonas tenax in haemodyalized patients--serologic research

Author

A, Ioli, M, Ferlazzo, M T, Fossari, C, Gembillo, B, Skotarczak, A, Vasi, A, Verzera, F, Torre, A, Mallamace, and G, Bellinghieri

Subjects
Renal Dialysis, Chronic Disease, Trichomonas, Animals, Antibodies, Protozoan, Humans, Trichomonas Infections, Uremia
Published
1987

37. [Influence of various dialyzers on acid-base balance in hemodialysis]

Author

G, Bellinghieri, V, Savica, A, Mallamace, E, Corvaja, C, di Stefano, P, Martinez, A, Granata, and F, Consolo

Subjects
Acid-Base Equilibrium, Adult, Male, Renal Dialysis, Humans, Female, Blood Gas Analysis, Middle Aged
Abstract

Various dialyzers and acid-base balance in haemodialysis: 12 patients aged 32 to 52 years in periodic haemodialysis (4hx3) with residue diuresis absent, were examined during four trimestrial cycles with four different dialyzers (Nephross 16 F I60, Gambro Lundia Optima I3,5 micron, RP 5I0, Vita 2). The acid-base balance was examined 30 days after starting of each cycle. The results are reported and discussed.

Published
1980

38. [Regulation of the renin-angiotensin-aldosterone system. Role of the prostaglandins]

Author

N, Frisina, M, Buemi, A, Lasco, G, Bellinghieri, F, Lo Schiavo, and D, Ceruso

Subjects
Adult, Angiotensin II, Indomethacin, Posture, Renin, Adrenal Cortex, Prostaglandins, Humans, Natriuresis, Middle Aged, Kidney, Aldosterone
Abstract

PRA (in the supine and erect subject) and urinary sodium before and after acute treatment (100 mg i.m.) and chronic treatment (100 mg per os for 8 days) were examined in two groups of subjects with no signs of cardiovascular or renal disease. It was found that indomethacin, which is a well-known inhibitor of prostaglandin synthesis, reduced PRA levels in basal conditions and as a result of postural stimulation, without causing any appreciable change in urinary sodium. Regulation of the PRA on the part of the renal prostaglandins is postulated and its probable mechanisms discussed.

Published
1978

39. Mixing evaluation of biocarbon prosthesis by radioactive tracer

Author

G, Bellinghieri, M G, Tripepi, A, Mallamace, S, Rotondo, and V, Savica

Subjects
Bioprosthesis, Arteriovenous Shunt, Surgical, Renal Dialysis, Humans, Kidney Failure, Chronic, Female, Middle Aged, Prosthesis Design, Carbon, Blood Vessel Prosthesis
Published
1983

40. [Toxic adenoma and thyroid diseases. Scintigraphic and clinical observations]

Author

G, Squadrito, N, Frisina, M, Emanuele, G, Bellinghieri, and M, Quartarone

Subjects
Adenoma, Adult, Male, Middle Aged, Thyroid Function Tests, Iodoproteins, Hyperthyroidism, Diagnosis, Differential, Humans, Triiodothyronine, Female, Basal Metabolism, Thyroid Neoplasms, Radionuclide Imaging
Published
1973

41. [Uric acid and kidney function in osteoarthrosis]

Author

G, Squadrito, D, Ceruso, M, Quartarone, and G, Bellinghieri

Subjects
Adult, Cholesterol, Osteoarthropathy, Primary Hypertrophic, Humans, Middle Aged, Kidney, Lipids, Aged, Uric Acid
Published
1970

42. New pharmacoeconomic option in uremic anemia management

Author

Guido Bellinghieri, Biagio Ricciardi, Vincenzo Savica, Domenico Santoro, L. Mantovani, V. Savica, L. Mantovani, D. Santoro, B. Ricciardi, and G. Bellinghieri

Subjects
Male, medicine.medical_specialty, business.industry, Cost-Benefit Analysis, Anemia, General Medicine, medicine.disease, Anemia management, Drug Costs, Recombinant Proteins, Nephropathy, Nephrology, Hematinics, medicine, Humans, Darbepoetin alfa, Female, Intensive care medicine, business, Erythropoietin, Aged, Uremia
Published
2007

43. Horseshoe Kidney: 500 Years From the First Report in the Literature.

Author

Gembillo G, Bellinghieri G, Savica V, and Santoro D

Subjects
Humans, Male, Female, Kidney diagnostic imaging, Kidney blood supply, Arteries, Veins, Fused Kidney complications, Fused Kidney diagnostic imaging, Renal Insufficiency, Chronic
Abstract

Horseshoe kidney or ren arcuatus is the most common renal fusion anomaly, with an incidence of 1:500 in the normal population and a male predominance of 2:1. In >90% of cases, the fusion occurs along the inferior pole. It may vary in location, orientation, and arterial and venous anatomy. In 1522, Berengario da Carpi described this renal malformation for the first time in his masterpiece "Isagogae breves" (Introduction to Anatomy). He reported the results of a postmortem examination in the public autopsy room of the University of Bologna, describing "kidneys that are continuous as if they were a kidney, with two emulsifying veins, two emulsifying arteries, two ureteral outlets." In 1564, Leonardo Botallo described and illustrated the features of this atypical anatomical representation, and later, in 1602, Leonard Doldius added further details by examining this anatomical feature during an autopsy. In 1761, Giovanni Battista Morgagni discussed this condition not only as a rare anatomical curiosity found only in necroscopy but also discussed its physiological aspect. In the nineteenth century, with the advent of renal surgery, the horseshoe kidney played a more important role in urological diagnosis and treatment, and its identification became more frequent. With the advent of pyelography, imaging reports of the horseshoe kidney allowed a more accurate representation of the anatomical variants, which was particularly useful in preoperative assessment and outcomes. Berengario da Carpi laid the foundation for a better knowledge of this anatomical anomaly. Five hundred years after the first report in the literature, relevant advances have been made in the management of complications associated with horseshoe kidney and in diagnosis, confirming the need to monitor individuals with this condition who are at higher risk of developing chronic kidney disease.

Published
2023
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44. Franz Volhard: 150th Birth Anniversary of a Father of Nephrology and Hypertension.

Author

Santoro D, Bellinghieri G, Savica V, and Gembillo G

Subjects
Humans, History, 20th Century, History, 19th Century, Anniversaries and Special Events, Kidney, Nephrology, Hypertension diagnosis, Hypertension, Renovascular, Glomerulonephritis
Abstract

Franz Volhard (May 2, 1872, to May 24, 1950) was a German clinician and researcher who made outstanding contributions to the field of nephrology and hyper-tension. His studies led to important developments in knowledge about the pathophysiology of the kidney and its relationship to cardiovascular disease. He contributed to a better understanding of the mechanisms underlying renovascular hypertension by explaining the crucial relationship between the decrease in renal blood flow and the increase in blood pressure. He also introduced a precise classification of the different types of hypertension and the associated renal involvement. In collaboration with Karl Theodor Fahr (1877-1945), he developed a new classification of Bright's disease (nephritis), which was published in the book Die Brightsche Nierenkrankheit. Klinik, Pathologie und Atlas, and revolutionized the concepts behind the mechanisms of glomerulonephritis. During his distinguished career, Volhard headed departments of internal medicine at the Luisenhospital in Dortmund (1905-1910) and in Mannheim (1910-1918). In 1918, he became chairman of the Department of Internal Medicine at the University of Halle, his alma mater, until 1928, the same year he became chairman of the Department of Internal Medicine at the University of Frankfurt until 1938. Volhard continued his successful career until 1950, when he died of complications from a car accident. The worldwide medical com-munity greatly appreciated Franz Volhard's scientific contribution. The International Society of Hypertension posthumously presented him with the "Franz Volhard Award." The aim of this article is to commemorate the importance of this giant of nephrology 150 years after his birth.

Published
2023
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45. The Mysterious Life of Jeronimus Ruscelli and His Contribution to Nephrology (1504-1566).

Author

Bellinghieri G, Gembillo G, Savica V, and Santoro D

Subjects
Humans, History, 16th Century, Nephrology history
Abstract

Jeronimo Ruscelli was a mysterious humanist of great fame. He was born in Viterbo between 1504 and 1518 and died in Venice in 1566. Very little is known about Ruscelli's life, but based on his extensive literary output we can assume that he was endowed with remarkable intellectual abilities and a propensity for varied interests. At a young age, he developed a strong interest in classical studies and attended the court of Cardinal Marini Grimani in Utini. After completing his studies at the University of Padua, he participated in the founding of a humanist academy, the Accademia degli Sdegnati (the Scornful Academy). After his fruitful experience in Rome, he moved to the Neapolitan residence of Marquis Alfonso D'Avalos. Here, Ruscelli founded an "Academy of Secrets", composed of a group of humanists and nobles who had an extensive culture and had different experiences but similar interests. During these productive years, under the pseudonym Alexius Pedemontanus, he wrote one of his masterpieces, The Secreti, an important historical documentary manual of great value. In this book, the author proposes therapies for a wide variety of diseases, claiming in most cases that they have been experimentally and successfully tested in the presence of witnesses in at least 3 clinical cases. Ruscelli composed an extensive version of The Secreti, the Secreti Novi. In this book he reported more than a thousand recipes, the substances used were of a great variety and sometimes curious. According to Ruscelli, the recipes in this updated version of the book were "easy for anyone to make, of little effort, and useful for all kinds of people." The topics of this masterpiece range from general medical suggestions to more specific indications, with a wide variety of recipes and treatments of nephrological and urological interest.

Published
2023
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49. Cystic Fibrosis: A Risk Condition for Renal Disease.

Author

Santoro D, Postorino A, Lucanto C, Costa S, Cristadoro S, Pellegrino S, Conti G, Buemi M, Magazzù G, and Bellinghieri G

Subjects
Adult, Female, Follow-Up Studies, Humans, Italy, Male, Pilot Projects, Prevalence, Retrospective Studies, Risk Factors, Cystic Fibrosis epidemiology, Kidney Failure, Chronic epidemiology, Proteinuria epidemiology
Abstract

Objective: Cystic fibrosis (CF) is the most common autosomal recessive disease affecting the Caucasian population, with a birth incidence ranging between 1:2,500 and 1:1,800. It is caused by mutations in the CF transmembrane regulator gene which is localized on 7 chromosomes. Renal disease is reported as a relatively rare complication in adult patient with CF. We evaluated proteinuria and chronic renal failure (CRF) in a population of patients with CF., Methods: A retrospective study was carried out in a referral center for CF at University of Messina in Italy. We identified all patients with renal disease, characterized by proteinuria and/or CRF, during the period 2007 to 2012 and reviewed their medical records to assess influence on renal disease of genotype, number of pulmonary exacerbation, pancreatic insufficiency, pulmonary function, CF-related diabetes, and antibiotics courses., Results: From a population of 77 adult patients with CF, we identified 9 patients with proteinuria (11.7%), and 11 patients (14.28%) with CRF. Mean age was 35.6 (+5.1 standard deviation) years, 55% were female and 33% had diabetes mellitus. Renal biopsy was performed in 3 patients because of nephrotic syndrome in 1 patient and proteinuria with renal failure in the other 2 patients. Renal amyloidosis was disclosed in 2, whereas IgA nephropathy in 1 patient. The ΔF508 mutation in homozygosis was present in 44% of patients with proteinuria (vs. 27% of our CF population, relative risk 2.07), whereas genotype ΔF508/N1303K in 22%. ΔF508 allele mutation was present in 77.7% of proteinuric patients., Conclusions: Our study shows a higher prevalence of renal disease in patients with CF, than was previously described. The main reason may be related to increased life expectancy because of better management. Moreover, patients with ΔF508 homozygosis had higher risk of proteinuria., (Copyright © 2017 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.)

Published
2017
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50. The management of kidney stones as suggested by Goeury-Duvivier.

Author

Bellinghieri G, Satta E, Savica V, Gembillo G, Salvo A, Buemi M, and Santoro D

Subjects
Equipment Design, France, History, 19th Century, Kidney Calculi therapy, Nephrology instrumentation, Kidney Calculi history, Nephrology history
Abstract

The management of kidney stones has always been a big problem for doctors of all time. Goeury Duvivier in his masterpiece "Guide des malades atteints daffections de voie urinaires ou des organes de la gnration chez lhomme et chez la femme shows us the different kind of diseases which affects the urinary tract and in particular highlights the list of the main methods that during the history characterized the treatment of renal calculi. Duvivier gives us the descriptions of invasive innovative techniques of the time, the Taille, the Lithotripsy and Lithotomy and their negative effects or limits for each technique. He also describes the different kind of palliative methods used in the 19th century to treat renal lithiasis and the clinical case reports of the time.

Published
2016

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