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1. Neoplastic transformation of anal condyloma

Author

P. C. Meinero, S. Ferrando, E. Brignole, G. Accarpio, C. Lapini, C. Carli, T. Ragusa, and S. Zoli

Subjects
Anal condyloma, Local excision, Pathology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Gastroenterology, Disease, medicine.disease, Colorectal surgery, Metastasis, Squamous carcinoma, Radiation therapy, Medicine, Surgery, Neoplastic transformation, business
Abstract

May one speak of precancerous lesion in the presence of perianal condyloma acuminata? In literature there are numerous reports of neoplastic transformation of anal condylomatosis to such an extent as these reports are comparable to extra-mammary Paget’s disease, to the giant condylomatosis of Buschke-Lowenstein and Bowen’s disease. Risk factors for malignant or premalignant change were: sexual orientation (homosexual or bisexual), HIV status and location above the dentate line. In our experience, in cases correlation between anal squamous carcinoma and condylomatosis has been established, it had occurred in 1 case, 18 months after local excision; another following radiotherapy cycle, a development at the same site of the surgical operation with metastasis in an inguinal lymph node. This latter case induces us to deem how necessary a meticulous follow-up in patients submitted to local excision of anal condylomas.

Published
1997

2. Outpatient treatment of hemorrhoids with a combined technique: results in 7850 cases

Author

S. Menoni, G. Accarpio, F. Ballari, A. Cariati, R. Zaffarano, G. Ravera, R. Puglisi, and F.T. Accarpio

Subjects
Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Infrared coagulation, Rubber band ligation, Hemorrhoids, Severity of Illness Index, Postoperative Complications, Outcome Assessment, Health Care, Sclerotherapy, medicine, Ambulatory Care, Outpatient clinic, Humans, Ligation, Aged, Retrospective Studies, Aged, 80 and over, Laser Coagulation, business.industry, Gastroenterology, Middle Aged, medicine.disease, Combined Modality Therapy, Colorectal surgery, Surgery, Anesthesia, Itching, Female, medicine.symptom, business, Abdominal surgery
Abstract

A combination of sclerotherapy, rubber band ligation and infrared coagulation was performed in 7850 patients seen an outpatient clinic over a period of 9 years. The most common symptom was bleeding followed by prolapse, pain and itching. Results were considered satisfactory in 7100 patients (90.5%); 750 (9.5%) required a formal hemorrhoidectomy. Complications were mild to moderate pain in 1777 cases (22.6%), severe pain in 157 cases (2.2%), mild hemorrhage in 199 (2.5%) and hemorrhage requiring transfusion in 10 cases (0.1%). In conclusion, non-surgical outpatient treatment has a great impact on patient's perception of the disease and results in considerable savings for the healthcare system.

Published
2003

3. [Adhesive peritonitis caused by a foreign body. A case report]

Author

E, Brignole, T, Testa, E, Squillario, E, Tonelli, C, Carli, M, Barbanera, G L, Ansaldo, A, Chiappori, T, Ragusa, and G, Accarpio

Subjects
Postoperative Complications, Surgical Staplers, Adolescent, Granuloma, Foreign-Body, Iatrogenic Disease, Humans, Female, Peritonitis, Foreign Bodies
Abstract

After investigation of the international literature on this subject, the authors describe a case report of adhesive-stenotic and retractile peritonitis, very likely caused bt a foreign body reaction (surgical stitches, gloves, rice powder, etc.?). This case-report is interesting both to remember the existence of this pathology and to limit its iatrogenic development. In conclusion, it is advisable to wash surgical gloves with sterile solutions and to limit enlarged bowel resections mostly in young people.

Published
1995

4. [Prognostic significance of cell-mediated immune response in patients with colorectal carcinoma. Preliminary results]

Author

T, Testa, E, Brignole, E, Squillario, E, Galgano, M, Barbanera, and G, Accarpio

Subjects
Male, Immunity, Cellular, Humans, Female, Colorectal Neoplasms, Prognosis, Follow-Up Studies
Abstract

Pre-operative skin test response has been evaluated in 50 cases of colorectal carcinoma. Cellular defense's depression was correlated with tumoral staging (p =0.001). In B2 and C groups, a higher incidence of metastatic and local recurrences was registered in subjects with low response. These last are suitable for a randomized trial including immunotherapy.

Published
1993

15. Possibilities of studying the deep-sub-fascial lymphatic system of the lower limbs

Author

E, Cariati, G, Accarpio, P, Molinello, R, Pellicci, M, Taviani, and F, Doria

Subjects
Adult, Lymphatic System, Male, Leg, Contrast Media, Humans, Lymphography, Female, Middle Aged, Aged, Neoplasm Staging
Abstract

After mentioning the lymphangiographical methods for the study of the lower limb channels, the authors illustrate a new technique which allows, in at least 15% of cases, the simultaneous study of both the superficial and deep lymphatic systems.

Published
1979

16. Experience with local rectal cancer excision in light of two recent preoperative diagnostic methods

Author

F. Claudiani, G. Accarpio, D. Davini, S. Saitta, G. Scopinaro, and G. Mallarini

Subjects
Adult, Male, medicine.medical_specialty, Local excision, Diagnostic methods, Colorectal cancer, Rectum, Scintigraphy, Surgical oncology, medicine, Humans, Neoplasm Invasiveness, Diagnostic Errors, Thallium, Radionuclide Imaging, Aged, Ultrasonography, Radioisotopes, medicine.diagnostic_test, business.industry, Abdominoperineal resection, Rectal Neoplasms, Gastroenterology, Technetium, General Medicine, Middle Aged, medicine.disease, Colorectal surgery, medicine.anatomical_structure, Lymphatic Metastasis, Female, Nuclear medicine, business
Abstract

This study analyzes the usefulness of two diagnostic methods: endorectal echotomography and adenolymphoscintigraphy. Echotomography is an important means for determining the extent of a tumor beyond the rectal wall, whereas lymphoscintigraphy is useful in demonstrating the metastatic locations in lymph nodes. These two modes of evaluation may permit an evaluation of the extent of the tumor and the possible involvement of regional lymph nodes before a surgical operation. Although the case material is limited, the statistical data can lead one to believe that, in the near future, a reasoned choice will be possible between local excision and abdominoperineal resection. The study includes 60 endorectal echotomographies and 26 lymphoscintigraphies (20 with 99mTc colloid and six with 201-Tl colloid).

Published
1987

21. Observations on the deep lymphatic circulation of the limbs and on its function: (the deep lymphatic vessels in the post-phlebitic syndrome of the lower extremities)

Author

E, Tosatti, G, Accarpio, and C, Campisi

Subjects
Adult, Lymphatic System, Male, Leg, Humans, Lymphography, Female, Middle Aged, Phlebitis
Abstract

In 60% of patients with post-phlebitic syndrome lymphography of the lower extremity shows involvement of the deep system. In 77% of the patients there was increase in the number and caliber of the deep lymphatic vessels. They frequently appear elongated, tortuous, and ectatic but usually do not show signs of insufficiency. It appears as if these vessels act as collaterals and compensate for difficiencies of the deep venous circulation. Multiple lympholymphatic and lymphovenous communications have been observed.

Published
1978

24. [The role of endorectal echography for determining the extent of an operation]

Author

G, Accarpio, G, Scopinaro, F, Claudiani, D, Davini, G, Mallarini, S, Saitta, G V, Tomasi, and A, Fazio

Subjects
Adult, Aged, 80 and over, Male, Rectal Neoplasms, Rectum, Technetium, Middle Aged, Thallium Radioisotopes, Evaluation Studies as Topic, Lymphatic Metastasis, Humans, Female, Lymph Nodes, Thallium, Radionuclide Imaging, Aged, Ultrasonography
Abstract

The paper discusses the usefulness of endorectal echotomography and adenolymphoscintigraphy--two new diagnostic methods which allow surgeons to know preoperatively tumor extension beyond the rectal wall and lymph nodes involvement. Though the statistical data presented are not numerous, it is hoped that, using these two diagnostic methods in cases of rectal tumors, surgeons will be able to choose better between local excision and abdominoperineal resection thus avoiding unnecessary and mutilating operations.

Published
1989

32. Outpatient treatment of hemorrhoids with a combined technique: results in 7850 cases.

Author

Accarpio G, Ballari F, Puglisi R, Menoni S, Ravera G, Accarpio FT, Cariati A, and Zaffarano R

Subjects
Adult, Aged, Aged, 80 and over, Combined Modality Therapy methods, Female, Humans, Ligation methods, Male, Middle Aged, Outcome Assessment, Health Care, Retrospective Studies, Severity of Illness Index, Ambulatory Care methods, Hemorrhoids surgery, Hemorrhoids therapy, Laser Coagulation methods, Postoperative Complications, Sclerotherapy methods
Abstract

A combination of sclerotherapy, rubber band ligation and infrared coagulation was performed in 7850 patients seen an outpatient clinic over a period of 9 years. The most common symptom was bleeding followed by prolapse, pain and itching. Results were considered satisfactory in 7100 patients (90.5%); 750 (9.5%) required a formal hemorrhoidectomy. Complications were mild to moderate pain in 1777 cases (22.6%), severe pain in 157 cases (2.2%), mild hemorrhage in 199 (2.5%) and hemorrhage requiring transfusion in 10 cases (0.1%). In conclusion, non-surgical outpatient treatment has a great impact on patient's perception of the disease and results in considerable savings for the healthcare system.

Published
2002
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33. Prognostic evaluation of stage B colon cancer patients is improved by an adequate lymphadenectomy: results of a secondary analysis of a large scale adjuvant trial.

Author

Prandi M, Lionetto R, Bini A, Francioni G, Accarpio G, Anfossi A, Ballario E, Becchi G, Bonilauri S, Carobbi A, Cavaliere P, Garcea D, Giuliani L, Morziani E, Mosca F, Mussa A, Pasqualini M, Poddie D, Tonetti F, Zardo L, and Rosso R

Subjects
Adenocarcinoma mortality, Aged, Colonic Neoplasms mortality, Female, Follow-Up Studies, Humans, Lymph Nodes pathology, Male, Middle Aged, Neoplasm Staging, Prognosis, Survival Rate, Time Factors, Adenocarcinoma pathology, Adenocarcinoma surgery, Colonic Neoplasms pathology, Colonic Neoplasms surgery, Lymph Node Excision, Outcome Assessment, Health Care
Abstract

Objective: To determine if the extent of lymphadenectomy (number of recovered lymph nodes) was associated with long-term outcome in patients operated on for stage B and C colon cancer., Summary Background Data: Lymphatic spreading is the main prognostic indicator in colon cancer patients, although the optimal extent of lymphadenectomy and its prognostic impact are still unknown., Methods: In 3,648 patients (median follow-up 3.6 years) enrolled in two consecutive INTACC multicentric trials on adjuvant therapy for colon cancer, we studied the association of the number of recovered nodes with overall survival and relapse free survival by means of univariate and Cox regression analysis., Results: The worst overall survival was related to ages > 65 (risk ratio [RR] = 1.30), higher grading (RR = 1.96). Better overall survival was related to female gender (RR = 0.80) and to higher number of recovered nodes (8-12 nodes, RR = 0.46, 13-17 nodes, RR = 0.76, nodes > or = 18, RR = 0.79). The same pattern was observed for relapse free survival. Longer overall and relapse free survival were related to a higher number of recovered nodes with P =.034 and P =.003 respectively (stratified analysis for absence or presence of positive nodes). Stage B patients with fewer than 7 nodes in the specimen had both shorter overall survival (P =.0000) and relapse free survival (P =.0016) than the other B patients. Outcome of stage C patients was not related to the number of recovered nodes (P =.28 and 0.12 respectively). The interaction test between stage of disease and number of recovered nodes was statistically significant (P =.017)., Conclusions: Stage B patients with a small number of examined nodes may be understaged. Thus, these patients might be considered for adjuvant therapy because of their poorer life expectancy than other stage B patients. For stage C patients, the number of recovered nodes does not seem to affect long-term outcome.

Published
2002
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34. [Adhesive peritonitis caused by a foreign body. A case report].

Author

Brignole E, Testa T, Squillario E, Tonelli E, Carli C, Barbanera M, Ansaldo GL, Chiappori A, Ragusa T, and Accarpio G

Subjects
Adolescent, Female, Foreign Bodies surgery, Granuloma, Foreign-Body complications, Humans, Iatrogenic Disease, Peritonitis surgery, Postoperative Complications, Surgical Staplers, Foreign Bodies complications, Peritonitis etiology
Abstract

After investigation of the international literature on this subject, the authors describe a case report of adhesive-stenotic and retractile peritonitis, very likely caused bt a foreign body reaction (surgical stitches, gloves, rice powder, etc.?). This case-report is interesting both to remember the existence of this pathology and to limit its iatrogenic development. In conclusion, it is advisable to wash surgical gloves with sterile solutions and to limit enlarged bowel resections mostly in young people.

Published
1995

35. [Prognostic significance of cell-mediated immune response in patients with colorectal carcinoma. Preliminary results].

Author

Testa T, Brignole E, Squillario E, Galgano E, Barbanera M, and Accarpio G

Subjects
Female, Follow-Up Studies, Humans, Immunity, Cellular, Male, Prognosis, Colorectal Neoplasms immunology
Abstract

Pre-operative skin test response has been evaluated in 50 cases of colorectal carcinoma. Cellular defense's depression was correlated with tumoral staging (p = < 0.001). In B2 and C groups, a higher incidence of metastatic and local recurrences was registered in subjects with low response. These last are suitable for a randomized trial including immunotherapy.

Published
1993

38. [Ileo-anal canal-ano-stomy. Cases of four school and recent modifications].

Author

Accarpio G, Scordamaglia R, Mignone D, Accarpio V, Papi M, and Larghero GC

Subjects
Adolescent, Adult, Colitis, Ulcerative surgery, Crohn Disease surgery, Female, Humans, Intestinal Polyps surgery, Male, Megacolon, Toxic surgery, Methods, Middle Aged, Anal Canal surgery, Ileum surgery
Published
1984

39. [Use of afferrent loop in re-establishment of the duodenal transport in the management of dumping syndrome following gastric resection].

Author

Cariati E, Accarpio G, and Mallamaci G

Subjects
Adult, Digestion, Dumping Syndrome metabolism, Duodenum metabolism, Duodenum surgery, Female, Humans, Jejunum surgery, Ligation, Male, Osmolar Concentration, Postoperative Complications diagnostic imaging, Radiography, Afferent Loop Syndrome prevention & control, Dumping Syndrome surgery
Published
1974

40. Unusual chylolymphedema of congenital origin.

Author

Accarpio G, Larghero GC, Vigna S, Roccatagliata C, Rocca G, and Nati R

Subjects
Humans, Male, Chyle diagnostic imaging, Lymphedema diagnostic imaging, Lymphography
Published
1984

41. [Extensive surgery for cancer of the colorectum].

Author

Prior C and Accarpio G

Subjects
Adult, Aged, Colonic Neoplasms pathology, Female, Humans, Male, Middle Aged, Neoplasm Invasiveness, Rectal Neoplasms pathology, Colonic Neoplasms surgery, Rectal Neoplasms surgery
Published
1985

45. Experience with local rectal cancer excision in light of two recent preoperative diagnostic methods.

Author

Accarpio G, Scopinaro G, Claudiani F, Davini D, Mallarini G, and Saitta S

Subjects
Adult, Aged, Diagnostic Errors, Female, Humans, Lymphatic Metastasis, Male, Middle Aged, Radioisotopes, Radionuclide Imaging, Rectal Neoplasms diagnostic imaging, Rectal Neoplasms pathology, Technetium, Thallium, Ultrasonography methods, Neoplasm Invasiveness diagnosis, Rectal Neoplasms surgery
Abstract

This study analyzes the usefulness of two diagnostic methods: endorectal echotomography and adenolymphoscintigraphy. Echotomography is an important means for determining the extent of a tumor beyond the rectal wall, whereas lymphoscintigraphy is useful in demonstrating the metastatic locations in lymph nodes. These two modes of evaluation may permit an evaluation of the extent of the tumor and the possible involvement of regional lymph nodes before a surgical operation. Although the case material is limited, the statistical data can lead one to believe that, in the near future, a reasoned choice will be possible between local excision and abdominoperineal resection. The study includes 60 endorectal echotomographies and 26 lymphoscintigraphies (20 with 99mTc colloid and six with 201-Tl colloid).

Published
1987
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46. Pilonidal sinus with an anal canal fistula. Report of a case.

Author

Accarpio G, Davini MD, Fazio A, Senussi OH, and Yakubovich A

Subjects
Adult, Humans, Male, Pilonidal Sinus surgery, Rectal Fistula surgery, Pilonidal Sinus complications, Rectal Fistula complications
Abstract

A rare case of a pilonidal cyst with the fistulous tract situated inside the anal canal is described. This is the sixth such case in the medical literature.

Published
1988
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48. [Possible relation between cholecystectomy and cancer of the colon].

Author

Beatini M, Davini MD, Fazio A, Vigna S, Cantello C, and Accarpio G

Subjects
Adult, Aged, Aged, 80 and over, Feces, Female, Food, Humans, Male, Middle Aged, Adenocarcinoma etiology, Cholecystectomy adverse effects, Colonic Neoplasms etiology, Rectal Neoplasms etiology
Published
1987

49. [Description of a case of gastric carcinoid tumor].

Author

Accarpio G, Arcuri V, Pozzati A, Saccomanni G, and Scordamaglia R

Subjects
Carcinoid Tumor pathology, Humans, Male, Middle Aged, Stomach Neoplasms pathology, Carcinoid Tumor diagnosis, Stomach Neoplasms diagnosis
Published
1978

50. [The role of endorectal echography for determining the extent of an operation].

Author

Accarpio G, Scopinaro G, Claudiani F, Davini D, Mallarini G, Saitta S, Tomasi GV, and Fazio A

Subjects
Adult, Aged, Aged, 80 and over, Evaluation Studies as Topic, Female, Humans, Lymph Nodes diagnostic imaging, Lymphatic Metastasis, Male, Middle Aged, Radionuclide Imaging, Rectal Neoplasms diagnosis, Rectal Neoplasms surgery, Rectum diagnostic imaging, Rectum surgery, Technetium, Thallium, Thallium Radioisotopes, Rectum pathology, Ultrasonography instrumentation, Ultrasonography methods
Abstract

The paper discusses the usefulness of endorectal echotomography and adenolymphoscintigraphy--two new diagnostic methods which allow surgeons to know preoperatively tumor extension beyond the rectal wall and lymph nodes involvement. Though the statistical data presented are not numerous, it is hoped that, using these two diagnostic methods in cases of rectal tumors, surgeons will be able to choose better between local excision and abdominoperineal resection thus avoiding unnecessary and mutilating operations.

Published
1989

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