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Aim: The present study aims to establish the role of serum CGRP and SP levels in the disease pathophysiology in patients with dialysis headache not accompanied by primary or secondary headaches, and also whether there is a correlation between these vasoactive peptides and the severity of headache. Method: This study was designed as prospective and multicenter. A total of 30 dialysis headache patients and 30 patients without headache as the control group in the Nephrology outpatient clinics which implement similar dialysis procedures were included in the study. Blood samples were taken from all the patients before hemodialysis, and post‐hemodialysis samples were collected. CGRP and SP contents in serum samples were measured using the ELISA method with detection kits. Results: A total of 60 patients were included in the study with 17 female and 13 male patients in the dialysis headache group and 18 female and 12 male patients in the control group, and there were no significant differences in sex and age between the groups. CGRP levels in the headache group were found to be significantly higher compared with the control group both before and after hemodialysis. Furthermore, pre‐hemodialysis CGRP levels were significantly higher than post‐hemodialysis CGRP levels in both the headache and control groups. Serum SP levels in the headache group were found to be higher compared with the control group both before and after hemodialysis, there was no significant difference between the groups. Even though SP levels in both groups decreased after hemodialysis, there was again no significant difference between the groups. No correlation was found between the patients' severity of headache and serum CGRP and SP levels. Conclusion: This study concludes that CGRP and SP, even though the latter is not statistically significant, play a role in the pathophysiology of the dialysis headache, and further studies with a larger and more specific patient population may reveal the relationship between the neuropeptides and dialysis headache more clearly. [ABSTRACT FROM AUTHOR]

Introduction: The most common finding in comparative electroencephalography (EEG) exams in patients with Parkinson's disease and healthy individuals in similar age groups is the increased generalized or localized slow-wave activity. The present study aims to investigate the EEG findings in patients with Parkinson's disease and to determine their possible contribution to diagnosis. Methods: The study included patients followed up by the Movement Disorders Outpatient Clinic for diagnosed Parkinson's disease. The Unified Parkinson's Disease Rating Scale (UPDRS) was used to rate the clinical disability in patients with Parkinson's disease with and without dementia based on DSM-V criteria. Patients were also evaluated using the Standardised Mini-Mental State Examination (SMME), the Geriatric Depression Scale (GDS), and the Neuropsychiatric Inventory (NPI). EEG recordings were performed according to the 10-20 system in both the patient group and healthy individuals in similar age groups with no metabolic/organic diseases. Results: 60 patients (16F, 44M, mean age: 69.23±11.56 years) diagnosed with Parkinson's disease were compared with a control group of 25 individuals (17F, 8M, mean age: 70.12±8.18 years). In the patient group, 19 patients (31.7%) showed EEG pathology in the form of 4-8 Hz theta wave activity interpreted as mild disorganization, while 2 patients (3.33%) showed nonspecific slow-wave activity on both hemispheres. In the control group, only 1 patient (4%) had pathological EEG findings. 47.6% of the patients with Parkinson's disease dementia showed EEG pathology. 2 patients with nonspecific slow-wave activity on both hemispheres were found to be from the Parkinson's disease dementia group. Patients with EEG pathology had higher UPDRS scores (p=0.011), lower SMME scores (p=0.002), and higher NPI scores (p=0.004). Discussion and Conclusion: The present study points out that there is a parallel between the development of dementia and EEG pathology in Parkinson's disease and thus EEG may be important in the diagnosis and follow-up of cognitive decline. [ABSTRACT FROM AUTHOR]

Ross syndrome is a rare syndrome consisting of areflexia, tonic pupil and segmental anhidrosis. It has been shown to accompany neuropsychiatric diseases such as psychiatric disorders, headache, and epilepsy. We report here a 19-year-old female who was the first case in which cyclic vomiting syndrome plus was shown to accompany Ross syndrome. [ABSTRACT FROM AUTHOR]

Copyright of Clinical Neuroscience / Ideggyógyászati Szemle is the property of LifeTime Media Kft. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Agri: Journal of the Turkish Society of Algology / Türk Algoloji (Ağrı) Derneği'nin Yayın Organıdır is the property of KARE Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objectives: Headache is one of the most common health problems, and it severely reduces the quality of life. The present study examines the efficacy of greater occipital nerve (GON) block in patients monitored for primary headaches., Methods: The present study includes 53 patients monitored by the headache outpatient clinic from March 2017 to June 2018, evaluates them for headache type, attack duration, attack frequency, severity of pain, and analgesic intake and compares the initial values with the follow-up values at months 1, 3, and 6., Results: The study group comprises 36 episodic migraine cases, 12 tension-type headache (TTH) cases, 4 chronic migraine cases, and 1 cluster headache case. In migraine group, VAS scores, attack durations, and the mean value of monthly number of attacks and analgesics taken significantly decrease compared to initial values at the end of the 6-month follow-up period. In TTH group, VAS scores, attack durations, and the mean value of monthly number of attacks and analgesics taken significantly decrease compared to initial values at the end of the 3-month follow-up period. Since only 2 of 12 patients completed the 6-month follow-up, although there was a decrease in the 6-month data, it was found to be statistically insignificant., Conclusion: Repetitive GON block is an effective treatment method for migraine and TTH.