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Using known procedures, alkylethers of pyridine-aldoxime not described as yet were prepared and transformed into pyridinium salts. The application of a solution of a,a'-di-iodo-dimethyl-ether proved especially useful in the synthesis of bisquarternary salts with formaldehyde-acetal bridge. All the new substances are ineffective in a paraoxon poisoning. On the other hand, some salts show protective action in soman intoxication.

The monobetaine derived from the AChE-ractivator bis-[4-hydroxyiminomethyl-pyridinium-(1)-methyl]-either dichloride (obidoxim; Toxogonin), was shown to be in solution an intramolecular CT-complex. Some betaines of quaternary salts of pyridine-aldoximes were isolated.