6 results on '"Gülsen, Yılmaz"'
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2. COVID-19 patients with altered steroid hormone levels are more likely to have higher disease severity
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Sevilay, Sezer, Ceylan, Bal, Ayşe Kaya, Kalem, Bircan, Kayaaslan, Fatma, Eser, İmran, Hasanoglu, Esragül, Akıncı, Rahmet, Güner, Özcan, Erel, and Gülsen, Yılmaz
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Hydrocortisone ,Estradiol ,Dehydroepiandrosterone Sulfate ,Estrone ,17-alpha-Hydroxyprogesterone ,Endocrinology, Diabetes and Metabolism ,Cortodoxone ,Androstenedione ,COVID-19 ,Dihydrotestosterone ,17-alpha-Hydroxypregnenolone ,Androsterone ,Severity of Illness Index ,Endocrinology ,Tandem Mass Spectrometry ,Pregnenolone ,Humans ,Corticosterone ,Desoxycorticosterone ,Aldosterone ,Progesterone ,Chromatography, Liquid - Abstract
Purpose: This study aims to evaluate the correlations between the severity of the disease and serum steroid levels by analyzing the serum steroid levels in COVID-19 patients with different levels of disease progression and the control group.Methods: Morning plasma Aldosterone, 11-deoxycortisol, Androstenedione, 17- hydroxyprogesterone, Dihydrotestosterone (DHT), Dihydroepiandrostenedion (DHEA), Corticosterone, Dihydroepiandrostenedion sulfate (DHEAS), Estrone, 11- deoxycorticosterone, Cortisol, Corticosterone, Androsterone, Pregnenolone, 17- hydroxypregnenolone levels were measured in 153 consecutive patients were grouped as mild, moderate, and severe based on the WHO COVID-19 disease severity classification and the control group. Steroid hormone levels were analyzed at once with a liquid chromatography-tandem mass spectrometric method (LC-MS/MS). Results: In our study, all of the steroids except DHT and DHEAS were statistically significantly higher in the patients’ group than in the control group (p>0.001). Also, DHEA was an independent predictor of the disease severity with COVID-19Conclusions: Our study reveals that altered steroid hormone levels have a negative impact on COVID-19 prognosis by simultaneous measurement of steroid hormones levels with LC-MS/MS. Also, adrenal insufficiency due to COVID-19 is an endocrinological pathology that should be followed up.
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- 2022
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3. Predictors of Language Dominance: An Integrated Analysis of First Language Attrition and Second Language Acquisition in Late Bilinguals
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Monika S. Schmid and Gülsen Yılmaz
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bilingual development ,language attrition ,second language development ,late bilinguals ,language dominance ,language balance ,Psychology ,BF1-990 - Abstract
Late bilinguals who spend (part of) their adult lives in an environment where a language other than the one they learned in childhood is spoken typically experience a range of language development phenomena. Most obviously, they will acquire some level of receptive and/or productive knowledge of the new, or second, language (L2). How basic or advanced that level will be is determined by a range of environmental, experiential, attitudinal and individual factors. Secondly, they will most likely find the knowledge of their native language (L1) beginning to diverge from that of monolingual speakers in their country of origin, a process known as language attrition. In the course of this developmental process, some L2 skills may eventually match or even overtake the corresponding skill in the L1. This shift in the balance between L1 and L2 is the focus of investigations of language dominance. The present study explores language dominance in four migrant populations (Germans in the Netherlands and Canada, Turks and Moroccans in the Netherlands). Investigating both the development of formal/controlled skills and more automatic aspects of lexical access and fluency, we aim to attain an understanding of how extralinguistic factors contribute to the development of both languages. We argue that an integrated perspective can contribute more profound insights into the predictors of this complex process of bilingual development. In particular, our findings show that statistical models based on linear relationships fall short of capturing the full picture. We propose an alternative method of analysing data, namely discriminant function analysis, based on a categorisation of the populations, and demonstrate how this can enhance our understanding. Our findings suggest that different aspects of the bilingual experience contribute differently to language development, regardless of language combination and type of skill measured. Contrary to what previous research suggests, measures relating to the intensity of informal use of both the L1 and the L2 in daily life are important in determining whether someone is a good or a poor L1 maintainer, while high vs. low success in acquisition appears to be predominantly associated with personal factors such as educational level.
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- 2018
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4. The effect of acid use as a preservative on the results of biochemical tests measured in 24-h urine
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Ceylan Bal, Canan Topcuoğlu, Ahmet Rıfat Balık, Fatma Meriç Yılmaz, Özcan Erel, and Gülsen Yılmaz
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Norepinephrine ,Chlorides ,Epinephrine ,Dopamine ,Clinical Biochemistry ,Amylases ,Humans ,General Medicine ,Metanephrine ,Normetanephrine - Abstract
Twenty-four-hour urine measurements play a crucial role in the diagnosis, follow-up and treatment of various diseases. There are different approaches to the collection of urine in patients who need to collect multiple urine samples at a time, especially in hospitals with heavy workloads. In this study, we compared the sodium, potassium, chloride, amylase, calcium, creatinine, phosphorus, microalbumin, protein, magnesium, urea, uric acid, adrenaline, noradrenaline, dopamine, metanephrine, normetanephrine, vanillylmandelic acid, 5-hydroxyindoleacetic acid and homovanillic acid results of 24-h urine samples analyzed immediately without acid addition, which we accepted as the reference and baseline measurement, with the results of the samples analyzed after waiting for 24 h without acid addition, analyzed immediately with acid addition and analyzed after waiting for 24 h with acid addition. Chloride, microalbumin, amylase and protein tests, which are recommended to be measured in the sample without preservatives, are affected by acid addition. Adrenaline, noradrenaline and dopamine, which are the tests recommended to be measured in acid-added urine are degraded in the samples without acid, and the levels of metanephrine and normetanephrine were not significantly degraded in the absence of preservatives.
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- 2022
5. D Vitamini Düzeylerinin Aylara, Cinsiyete ve Yaşa Göre Değerlendirilmesi
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Elmas Öğüş, Hatice Sürer, Aytün Kılınç, Vildan Fidancı, Gülsen Yılmaz, Nermin Dindar, and Alpaslan Karakaş
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vitamin d ,variations ,age ,sex ,d vitamini ,varyasyon ,cinsiyet ,yaş ,Medicine ,Medicine (General) ,R5-920 - Abstract
Amaç: D vitamini, kalsiyum absorbsiyonu ve kemik metabolizmasında etkilidir. Ayrıca düşük D vitamini düzeyleri DM, HT, kanser ve otoimmun hastalıkların yer aldığı çoğu kronik hastalık ile de ilişkilidir. Bu çalışmada laboratuvarımızda 2012 yılı Ocak-Aralık ayları arasında çalışılan D vitamini düzeylerinin incelenmesi amaçlandı.Materyal ve Metod: 2012 yılında Ocak-Aralık ayları arasındaki 4168 hasta değerlendirildi ve yaş, cinsiyet ve D vitamini düzeyleri aylara göre gruplara ayrıldı.Bulgular: Çalışmamızda 3242 (% 77,8) kadın ve 926 (%22,2) erkek yer aldı. Hastaların D vitamini düzeyleri ortalaması 22,80±13,27 ng/mL, kadınlarda 22,49±13,88 ng/mL, erkeklerde 23,75±10,57 ng/mL idi. Hastaların % 47’inde (kadınlarda % 50, erkeklerde %38) < 20 ng/mL D vitamini seviyeleri vardı (D vitamin yetersizliği için cut-off). D vitamini yetersizliğinde mevsimsel değişiklikleri incelemek için ortalama D vitamini düzeyleri karşılaştırıldığında tüm gruplar arasında istatiksel olarak anlamlı fark bulundu ( p
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- 2015
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6. Chapter 11. First language attrition and bilingualism
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Monika S. Schmid and Gülsen Yılmaz
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060201 languages & linguistics ,First language ,0602 languages and literature ,05 social sciences ,medicine ,0501 psychology and cognitive sciences ,Attrition ,06 humanities and the arts ,medicine.disease ,Psychology ,Neuroscience of multilingualism ,050105 experimental psychology ,Linguistics - Published
- 2018
- Full Text
- View/download PDF
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