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1. Relationship between IGF-1 and body weight in inflammatory bowel diseases: Cellular and molecular mechanisms involved

Author

Guijarro, Luis G., Cano-Martínez, David, Toledo-Lobo, M.Val, Salinas, Patricia Sanmartín, Chaparro, María, Gómez-Lahoz, Ana M., Zoullas, Sofía, Rodríguez-Torres, Rosa, Román, Irene D., Monasor, Laura Sebastián, Ruiz-Llorente, Lidia, del Carmen Boyano-Adánez, María, Guerra, Iván, Iborra, Marisa, Cabriada, José Luis, Bujanda, Luis, Taxonera, Carlos, García-Sánchez, Valle, Marín-Jiménez, Ignacio, Acosta, Manuel Barreiro-de, Vera, Isabel, Martín-Arranz, María Dolores, Mesonero, Francisco, Sempere, Laura, Gomollón, Fernando, Hinojosa, Joaquín, Alvarez-Mon, Melchor, Gisbert, Javier P., Ortega, Miguel A., Hernández-Breijo, Borja, and on behalf of the PREDICROHN study group from GETECCU

Published
2021
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2. Abnormal Characterization and Distribution of Circulating Regulatory T Cells in Patients with Chronic Spinal Cord Injury According to the Period of Evolution

Author

Gómez-Lahoz, Ana M., primary, Girón, Sergio Haro, additional, Sanz, Jorge Monserrat, additional, Fraile-Martínez, Oscar, additional, Garcia-Montero, Cielo, additional, Jiménez, Diego J., additional, de Leon-Oliva, Diego, additional, Ortega, Miguel A., additional, Atienza-Perez, Mar, additional, Diaz, David, additional, Lopez-Dolado, Elisa, additional, and Álvarez-Mon, Melchor, additional

Published
2023
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3. Patients with Chronic Spinal Cord Injury and a Long Period of Evolution Exhibit an Altered Cytokine Production by CD4 and CD8 T Cell Populations

Author

Girón, Sergio Haro, primary, Gómez-Lahoz, Ana M., additional, Sanz, Jorge Monserrat, additional, Fraile-Martínez, Oscar, additional, Jiménez, Diego J., additional, Garcia-Montero, Cielo, additional, de Leon-Oliva, Diego, additional, Ortega, Miguel A., additional, Atienza-Perez, Mar, additional, Diaz, David, additional, Lopez-Dolado, Elisa, additional, and Álvarez-Mon, Melchor, additional

Published
2023
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4. Updated Views in Targeted Therapy in the Patient with Non-Small Cell Lung Cancer

Author

Ortega, Miguel A., primary, Pekarek, Leonel, additional, Navarro, Fátima, additional, Fraile-Martínez, Oscar, additional, García-Montero, Cielo, additional, Álvarez-Mon, Miguel Ángel, additional, Diez-Pedrero, Raúl, additional, Boyano-Adánez, María del Carmen, additional, Guijarro, Luis G., additional, Barrena-Blázquez, Silvestra, additional, Gómez-Lahoz, Ana M., additional, Haro, Sergio, additional, Arroyo, Mónica, additional, Monserrat, Jorge, additional, Saez, Miguel A., additional, and Alvarez-Mon, Melchor, additional

Published
2023
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5. Chronic Venous Disease during Pregnancy Causes a Systematic Increase in Maternal and Fetal Proinflammatory Markers

Author

Ortega, Miguel A., primary, Gómez-Lahoz, Ana M., additional, Sánchez-Trujillo, Lara, additional, Fraile-Martinez, Oscar, additional, García-Montero, Cielo, additional, Guijarro, Luis G., additional, Bravo, Coral, additional, De Leon-Luis, Juan A., additional, Saz, Jose V., additional, Bujan, Julia, additional, García-Honduvilla, Natalio, additional, Monserrat, Jorge, additional, and Alvarez-Mon, Melchor, additional

Published
2022
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6. Prognostic Value of Malondialdehyde (MDA) in the Temporal Progression of Chronic Spinal Cord Injury.

Author

Haro Girón, Sergio, Monserrat Sanz, Jorge, Ortega, Miguel A., Garcia-Montero, Cielo, Fraile-Martínez, Oscar, Gómez-Lahoz, Ana M., Boaru, Diego Liviu, de Leon-Oliva, Diego, Guijarro, Luis G., Atienza-Perez, Mar, Diaz, David, Lopez-Dolado, Elisa, and Álvarez-Mon, Melchor

Subjects
SPINAL cord injuries, PROGNOSIS, RECEIVER operating characteristic curves, MALONDIALDEHYDE, OXIDATIVE stress
Abstract

Background: Oxidative stress is a major signature of spinal cord injury (SCI). The altered levels of various oxidative stress markers have been demonstrated in acute and chronic SCI. However, the variation of these markers in patients with chronic SCI depending on the time since the initial injury has not been explored yet. Objective: Our aim was to measure plasma levels of malondialdehyde (MDA), a marker of lipid peroxidation in patients with SCI stratified in different periods of suffering the injury (0–5 years, 5–10 years, and more than 10 years). Patients and methods: This cross-sectional study enrolled patients with SCI (N = 105) from different periods of the lesion and healthy control (HC) subjects (N = 38): short period (SCI SP, N = 31, time of evolution less than 5 years); early chronic (SCI ECP, N = 32, time of evolution 5–15 years); and late chronic (SCI LCP, N = 42, time of evolution more than 15 years). The plasma levels of MDA were measured using a commercially available colorimetric assay. Results: Patients with SCI had significantly higher plasma levels of MDA than HC subjects. Receiver operating characteristic (ROC) curve analysis for plasma MDA levels in patients with SCI demonstrated areas under the curve (AUC) of 1 (HC vs. SCI-SP); 0.998 (HC vs. SCI-ECP); and 0.964 (HC vs. SCI-LCP). Additionally, three ROC curves were used to compare the different concentrations of MDA between the subgroups of patients with SCI, and the resulting AUCs were: 0.896 (SCI-SP vs. SCI-ECP); 0.840 (SCI-ECP vs. SCI-LCP); and 0.979 (SCI-SP vs. SCI-LCP). Conclusion: Plasma concentration of MDA can be considered as an oxidative stress biomarker to assess the prognosis of SCI in chronic stages. [ABSTRACT FROM AUTHOR]

Published
2023
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7. Applications of Polymeric Composites in Bone Tissue Engineering and Jawbone Regeneration

Author

Fraile-Martínez, Oscar, primary, García-Montero, Cielo, additional, Coca, Alejandro, additional, Álvarez-Mon, Miguel Angel, additional, Monserrat, Jorge, additional, Gómez-Lahoz, Ana M., additional, Coca, Santiago, additional, Álvarez-Mon, Melchor, additional, Acero, Julio, additional, Bujan, Julia, additional, García-Honduvilla, Natalio, additional, Asúnsolo, Ángel, additional, and Ortega, Miguel A., additional

Published
2021
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8. An Updated Review of SARS-CoV-2 Vaccines and the Importance of Effective Vaccination Programs in Pandemic Times

Author

García-Montero, Cielo, primary, Fraile-Martínez, Oscar, additional, Bravo, Coral, additional, Torres-Carranza, Diego, additional, Sanchez-Trujillo, Lara, additional, Gómez-Lahoz, Ana M., additional, Guijarro, Luis G., additional, García-Honduvilla, Natalio, additional, Asúnsolo, Angel, additional, Bujan, Julia, additional, Monserrat, Jorge, additional, Serrano, Encarnación, additional, Álvarez-Mon, Melchor, additional, De León-Luis, Juan A, additional, Álvarez-Mon, Miguel A., additional, and Ortega, Miguel A., additional

Published
2021
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9. Nutritional Components in Western Diet Versus Mediterranean Diet at the Gut Microbiota–Immune System Interplay. Implications for Health and Disease

Author

García-Montero, Cielo, primary, Fraile-Martínez, Oscar, additional, Gómez-Lahoz, Ana M., additional, Pekarek, Leonel, additional, Castellanos, Alejandro J., additional, Noguerales-Fraguas, Fernando, additional, Coca, Santiago, additional, Guijarro, Luis G., additional, García-Honduvilla, Natalio, additional, Asúnsolo, Angel, additional, Sanchez-Trujillo, Lara, additional, Lahera, Guillermo, additional, Bujan, Julia, additional, Monserrat, Jorge, additional, Álvarez-Mon, Melchor, additional, Álvarez-Mon, Miguel A., additional, and Ortega, Miguel A., additional

Published
2021
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10. Abnormal proinflammatory and stressor environmental with increased the regulatory cellular IGF-1/PAPP-A/STC and Wnt-1/β-Catenin canonical pathway in placenta of women with Chronic venous Disease during Pregnancy

Author

Ortega, Miguel A, primary, Fraile-Martínez, Oscar, additional, Saez, Miguel A, additional, Álvarez-Mon, Miguel A, additional, Gómez-Lahoz, Ana M, additional, Bravo, Coral, additional, Luis, Juan A De León, additional, Sainz, Felipe, additional, Coca, Santiago, additional, Asúnsolo, Ángel, additional, Monserrat, Jorge, additional, Guijarro, Luis G, additional, Álvarez-Mon, Melchor, additional, Bujan, Julia, additional, and García-Honduvilla, Natalio, additional

Published
2021
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