1,448 results on '"Gálvez, José"'
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2. Electric field control of the exchange field of a single spin impurity on a surface
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Zhang, Xue, Reina-Gálvez, Jose, Wu, Di'an, Martinek, Jan, Heinrich, Andreas J., Choi, Taeyoung, and Wolf, Christoph
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Electric control of spins offers faster switching and more localized manipulation compared to magnetic fields. In this work, we investigate static electric field effects on electron spin resonance of single molecules and atoms using scanning tunneling microscopy. We observe significant resonance frequency shifts when varying the applied DC voltage. These shifts cannot be adequately explained by g-factor changes or adsorbate displacement. Instead, we propose a model based on the control of the magnetic exchange field exerted to the spin impurity by the static electric field, which accurately reproduces the static electric field dependence of the resonance frequency. Our work provides crucial insights into electric field influence on surface spins, advancing fundamental understanding for many quantum technologies with efficient spin control via electric fields.
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- 2024
3. The Wide Field Monitor (WFM) of the China-Europe eXTP (enhanced X-ray Timing and Polarimetry) mission
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Hernanz, Margarita, Feroci, Marco, Evangelista, Yuri, Meuris, Aline, Schanne, Stéphane, Zampa, Gianluigi, Tenzer, Chris, Bayer, Jörg, Nowosielski, Witold, Michalska, Malgorzata, Kalemci, Emrah, Sungur, Müberra, Brandt, Søren, Kuvvetli, Irfan, Franco, Daniel Alvarez, Carmona, Alex, Gálvez, José-Luis, Patruno, Alessandro, Zand, Jean in' t, Zwart, Frans, Santangelo, Andrea, Bozzo, Enrico, Zhang, Shuang-Nan, Lu, Fangjun, Xu, Yupeng, Campana, Riccardo, Del Monte, Ettore, Ceraudo, Francesco, Nuti, Alessio, Della Casa, Giovanni, Argan, Andrea, Minervini, Gabriele, Antonelli, Matias, Bonvicini, Valter, Boezio, Mirko, Cirrincione, Daniela, Munini, Riccardo, Rachevski, Alexandre, Vacchi, Andrea, Zampa, Nicola, Rashevskaya, Irina, Ficorella, Francesco, Picciotto, Antonino, Zorzi, Nicola, Baudin, David, Bouyjou, Florent, Gevin, Olivier, Limousin, Olivier, Hedderman, Paul, Pliego, Samuel, Xiong, Hao, de la Rie, Rob, Laubert, Phillip, Aitink-Kroes, Gabby, Kuiper, Lucien, Orleanski, Piotr, Skup, Konrad, Tcherniak, Denis, Turhan, Onur, Bozkurt, Ayhan, and Onat, Ahmet
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The eXTP mission is a major project of the Chinese Academy of Sciences (CAS), with a large involvement of Europe. Its scientific payload includes four instruments: SFA, PFA, LAD and WFM. They offer an unprecedented simultaneous wide-band Xray timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study, both for the science and the instrumentation. Europe is expected to provide two of the four instruments: LAD and WFM; the LAD is led by Italy and the WFM by Spain. The WFM for eXTP is based on the design originally proposed for the LOFT ESA M3 mission, that underwent a Phase A feasibility study. It will be a wide field of view X-ray monitor instrument working in the 2-50 keV energy range, achieved with large-area Silicon Drift Detectors (SDDs), similar to the ones used for the LAD but with better spatial resolution. The WFM will consist of 3 pairs of coded mask cameras with a total combined field of view (FoV) of 90x180 degrees at zero response and a source localisation accuracy of ~1 arc min. The main goal of the WFM is to provide triggers for the target of opportunity observations of the SFA, PFA and LAD, in order to perform the core science programme, dedicated to the study of matter under extreme conditions of density, gravity and magnetism. In addition, the unprecedented combination of large field of view and imaging capability, down to 2 keV, of the WFM will allow eXTP to make important discoveries of the variable and transient X-ray sky, and provide X-ray coverage of a broad range of astrophysical objects covered under 'observatory science', such as gamma-ray bursts, fast radio bursts, gravitational wave electromagnetic counterparts. In this paper we provide an overview of the WFM instrument, explaining its design, configuration, and anticipated performance., Comment: 15 pages, 13 figures, Proceedings of SPIE 13093, Space Telescopes and Instrumentation 2024: Ultraviolet to Gamma Ray; Proceedings Volume 13093, Space Telescopes and Instrumentation 2024: Ultraviolet to Gamma Ray; 130931Y (2024); doi: 10.1117/12.3020020
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- 2024
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4. Quantum Spin-Engineering in On-Surface Molecular Ferrimagnets
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Huang, Wantong, Stark, Máté, Greule, Paul, Au-Yeung, Kwan Ho, Sostina, Daria, Gálvez, José Reina, Sürgers, Christoph, Wernsdorfer, Wolfgang, Wolf, Christoph, and Willke, Philip
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
The design and control of atomic-scale spin structures constitute major challenges for spin-based quantum technology platforms, including quantum dots, color centers, and molecular spins. Here, we showcase a strategy for designing the quantum properties of molecular spin qubits by combining tip-assisted on-surface assembly with electron spin resonance scanning tunneling microscopy (ESR-STM): We fabricate magnetic dimer complexes that consist of an iron phthalocyanine (FePc) molecule and an organometallic half-sandwich complex formed by the FePc ligand and an attached iron atom, Fe(C6H6). The total complex forms a mixed-spin (1/2,1) quantum ferrimagnet with a well-separated correlated ground state doublet, which we utilize for coherent control. As a result of the correlation, the quantum ferrimagnet shows an improved spin lifetime (>1.5 ${\mu}$s) as it is partially protected against inelastic electron scattering. Lastly, the ferrimagnet units also enable intermolecular coupling, that can be used to realize both ferromagnetic or antiferromagnetic structures. Thus, quantum ferrimagnets provide a versatile platform to improve coherent control in general and to study complex magnetic interactions., Comment: 17 pages, 4 figures
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- 2024
5. The STROBE-X Wide Field Monitor Instrument
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Remillard, Ronald A., Hernanz, Margarita, Zand, Jean in 't, Ray, Paul S., Bonvicini, Valter, Brandt, Søren, Brandt, Terri, Carmona, Alex, Evangelista, Yuri, Franco, Daniel Alvarez, Froning, Cynthia, Galvez, Jose-Luis, De Geronimo, Gianluigi, Grim, Martin, Kalemci, Emrah, Kuiper, Lucien, Kuvvetli, Irfan, Maccarone, Thomas J., Nowosielski, Witold, Pasham, Dheeraj R. R., Patruno, Alessandro, Persyn, Steven C., Roming, Peter W. A., Santangelo, Andrea, Schanne, Stephane, Tenzer, Christoph, Wilson-Hodge, Colleen A., Zampa, Gianluigi, and Zwart, Frans
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
The Wide Field Monitor (WFM) is one of the three instruments on the Spectroscopic Time-Resolving Observatory for Broadband Energy X-rays (STROBE-X) mission, which was proposed in response to the NASA 2023 call for a probe class mission. The WFM is a coded-mask camera system that would be the most scientifically capable wide-angle monitor ever flown. The field of view covers one third of the sky, to 50 percent mask coding, and the energy sensitivity is 2 to 50 keV. The WFM is designed to identify new X-ray transients and to capture spectral and timing changes in known sources with data of unprecedented quality. Science applications cover diverse classes, in including X-ray bursts that coincide with gravitational wave detections, gamma ray bursts and their transition from prompt emission to afterglow, subluminous GRBs that may signal shock breakout in supernovae, state transitions in accreting compact objects and their jets, bright flares in fast X-ray transients, accretion onset in transitional pulsars, and coronal flares from many types of active stars., Comment: 19 pages, 5 figures, accepted for publication in JATIS
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- 2024
6. Efficient driving of a spin-qubit using single-atom magnets
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Reina-Gálvez, Jose, Le, Hoang-Anh, Bui, Hong Thi, Phark, Soo-hyon, Lorente, Nicolás, and Wolf, Christoph
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Condensed Matter - Mesoscale and Nanoscale Physics ,Quantum Physics - Abstract
The realization of electron-spin resonance at the single-atom level using scanning tunneling microscopy has opened new avenues for coherent quantum sensing and quantum state manipulation at the ultimate size limit. This allows to build many-body Hamiltonians and the study of their complex physical behavior. Recently, a novel qubit platform has emerged from this field, raising questions about the driving mechanism from single-atom magnets. In this work, we demonstrate how single-atom magnets can be used to drive a nearby single spin qubit efficiently, while also addressing critical aspects related to the optimization of experimental parameters.
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- 2024
7. The Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology
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Gill, Erin E., Jia, Baofeng, Murall, Carmen Lia, Poujol, Raphaël, Anwar, Muhammad Zohaib, John, Nithu Sara, Richardsson, Justin, Hobb, Ashley, Olabode, Abayomi S., Lepsa, Alexandru, Duggan, Ana T., Tyler, Andrea D., N'Guessan, Arnaud, Kachru, Atul, Chan, Brandon, Yoshida, Catherine, Yung, Christina K., Bujold, David, Andric, Dusan, Su, Edmund, Griffiths, Emma J., Van Domselaar, Gary, Jolly, Gordon W., Ward, Heather K. E., Feher, Henrich, Baker, Jared, Simpson, Jared T., Uddin, Jaser, Ragoussis, Jiannis, Eubank, Jon, Fritz, Jörg H., Gálvez, José Héctor, Fang, Karen, Cullion, Kim, Rivera, Leonardo, Xiang, Linda, Croxen, Matthew A., Shiell, Mitchell, Prystajecky, Natalie, Quirion, Pierre-Olivier, Bajari, Rosita, Rich, Samantha, Mubareka, Samira, Moreira, Sandrine, Cain, Scott, Sutcliffe, Steven G., Kraemer, Susanne A., Joly, Yann, Alturmessov, Yelizar, consortium, CPHLN, consortium, CanCOGeN, Academic, VirusSeq Data Portal, network, Health, Fiume, Marc, Snutch, Terrance P., Bell, Cindy, Lopez-Correa, Catalina, Hussin, Julie G., Joy, Jeffrey B., Colijn, Caroline, Gordon, Paul M. K., Hsiao, William W. L., Poon, Art F. Y., Knox, Natalie C., Courtot, Mélanie, Stein, Lincoln, Otto, Sarah P., Bourque, Guillaume, Shapiro, B. Jesse, and Brinkman, Fiona S. L.
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Quantitative Biology - Genomics - Abstract
The COVID-19 pandemic led to a large global effort to sequence SARS-CoV-2 genomes from patient samples to track viral evolution and inform public health response. Millions of SARS-CoV-2 genome sequences have been deposited in global public repositories. The Canadian COVID-19 Genomics Network (CanCOGeN - VirusSeq), a consortium tasked with coordinating expanded sequencing of SARS-CoV-2 genomes across Canada early in the pandemic, created the Canadian VirusSeq Data Portal, with associated data pipelines and procedures, to support these efforts. The goal of VirusSeq was to allow open access to Canadian SARS-CoV-2 genomic sequences and enhanced, standardized contextual data that were unavailable in other repositories and that meet FAIR standards (Findable, Accessible, Interoperable and Reusable). The Portal data submission pipeline contains data quality checking procedures and appropriate acknowledgement of data generators that encourages collaboration. Here we also highlight Duotang, a web platform that presents genomic epidemiology and modeling analyses on circulating and emerging SARS-CoV-2 variants in Canada. Duotang presents dynamic changes in variant composition of SARS-CoV-2 in Canada and by province, estimates variant growth, and displays complementary interactive visualizations, with a text overview of the current situation. The VirusSeq Data Portal and Duotang resources, alongside additional analyses and resources computed from the Portal (COVID-MVP, CoVizu), are all open-source and freely available. Together, they provide an updated picture of SARS-CoV-2 evolution to spur scientific discussions, inform public discourse, and support communication with and within public health authorities. They also serve as a framework for other jurisdictions interested in open, collaborative sequence data sharing and analyses.
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- 2024
8. Analytic saddle spheres in S3 are equatorial
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Gálvez, José A., Mira, Pablo, and Tassi, Marcos P.
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- 2024
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9. Minimal surfaces and harmonic diffeomorphisms from the complex plane onto certain Hadamard surfaces
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Gálvez, José A. and Rosenberg, Harold
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- 2010
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10. Analytic saddle spheres in $\mathbb{S}^3$ are equatorial
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Galvez, Jose A., Mira, Pablo, and Tassi, Marcos P.
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Mathematics - Differential Geometry ,53A10, 53C42 - Abstract
A theorem by Almgren establishes that any minimal $2$-sphere immersed in $\mathbb{S}^3$ is a totally geodesic equator. In this paper we give a purely geometric extension of Almgren's result, by showing that any immersed, real analytic $2$-sphere in $\mathbb{S}^3$ that is saddle, i.e., of non-positive extrinsic curvature, must be an equator of $\mathbb{S}^3$. We remark that, contrary to Almgren's theorem, no geometric PDE is imposed on the surface. The result is not true for $C^{\infty}$ spheres., Comment: 17 pages, 9 figures
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- 2023
11. Many-body non-equilibrium effects in all-electric electron spin resonance
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Reina-Gálvez, Jose, Wolf, Christoph, and Lorente, Nicolás
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Motivated by recent developments in measurements of electron spin resonances of individual atoms and molecules with the scanning tunneling microscope (ESR-STM), we study electron transport through an impurity under periodic driving as a function of the transport parameters in a model junction. The model consists of a single-orbital quantum impurity connected to two electrodes via time-dependent hopping terms. The hopping terms are treated at the lowest order in perturbation theory to recover a Lindblad-like quantum master equation with electron transport. As in the experiment, the ESR-STM signal is given by the variation of the long-time DC current with the driving frequency. The density-matrix coherences play an important role in the evaluation of the ESR-STM signal. Electron correlation is included in our impurity mode. The charging energy $U$ has significant influence on the spin dynamics depending on the sign and magnitude of the applied DC bias. Our model allows direct insight into the origin of the ESR signal from the many-body dynamics of the impurity.
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- 2023
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12. La experiencia electoral gaditana y su influencia en los albores de la República peruana
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Gálvez, José Francisco
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elecciones ,voto ,soberanía ,legitimidad ,nacionalidad ,Political institutions and public administration (General) ,JF20-2112 - Abstract
La conmemoración del bicentenario de la promulgación de la Constitución de la monarquía española, el 19 de marzo de 1812, ha sido la ocasión propicia para someter al análisis el proceso de génesis de la convocatoria de las Cortes generales y extraordinarias de Cádiz, así como los aportes más significativos de dicha Carta desde diferentes ámbitos. En este contexto decimonónico se puso de manifiesto el discurso de la soberanía del pueblo junto con el carácter representativo del Poder Legislativo, único capaz de redactarla y aprobarla. Este artículo aborda pasajes del funcionamiento de este colegiado a partir de los temas de soberanía, legitimidad y religión para orientarlos con posterioridad al establecimiento de las bases institucionales del Estado peruano durante sus primeros años.
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- 2012
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13. Electric-field-driven spin resonance by on-surface exchange coupling to a single-atom magnet
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Phark, Soo-hyon, Bui, Hong T., Ferrón, Alejandro, Fernández-Rossier, Joaquin, Reina-Gálvez, Jose, Wolf, Christoph, Wang, Yu, Yang, Kai, Heinrich, Andreas J., and Lutz, Christopher P.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Coherent control of individual atomic and molecular spins on surfaces has recently been demonstrated by using electron spin resonance (ESR) in a scanning tunneling microscope (STM). Here we present a combined experimental and modeling study of the ESR of a single hydrogenated Ti atom that is exchange-coupled to a Fe adatom located in 0.6-0.8 nm away. Continuous wave and pulsed ESR of the Ti spin showed a Rabi rate with two contributions, one from the tip and the other from the Fe, whose spin interactions with Ti were modulated by the radio-frequency electric field. The Fe contribution is comparable to the tip, as revealed from its dominance when the tip was retracted, and tunable using a vector magnetic field. Our new ESR scheme allows on-surface individual spins to be addressed and coherently controlled without the need for magnetic interaction with a tip. This study establishes a feasible implementation of spin-based multi-qubit systems on surfaces.
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- 2022
14. Effectiveness of a UV Treatment Using Light Emitting Diodes (LED) for the Inactivation of Phytoplanktonic Organisms Present in Two Reservoirs of Cádiz (Spain)
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Gento-Arazola, Pablo, Romero-Martínez, Leonardo, Nebot, Enrique, Acevedo-Merino, Asunción, Gálvez, Jóse Ángel, Moreno-Andrés, Javier, Bezaeva, Natalia S., Series Editor, Gomes Coe, Heloisa Helena, Series Editor, Nawaz, Muhammad Farrakh, Series Editor, Galvão, João Rafael da Costa Sanches, editor, Brito, Paulo, editor, Neves, Filipe dos Santos, editor, Almeida, Henrique de Amorim, editor, Mourato, Sandra de Jesus Martins, editor, and Nobre, Catarina, editor
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- 2024
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15. La instrucción violinística en la España Ilustrada: aportación ibérica al legado pedagógico del instrumento
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Gil de Gálvez, José Manuel
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violín ,Siglo XVIII ,música española ,educación musical ,instituciones educativas musicales ,métodos - Abstract
El papel del violín en la historiografía musical española y en la teoría e historia de la educación, han tenido hasta la fecha una escasa presencia a diferencia de las referencias bibliográficas que encontramos sobre el instrumento en otras historias nacionales que le han procurado una trascendencia, al menos, lo suficientemente amplia como para pertenecer a la historia universal de la música. La constatación bibliográfica de tales carencias nos lleva al planteamiento de la presente investigación sustanciando una hipótesis que pone en cuestión tal situación y delimita el objeto de estudio a “La dimensión violinística en la España dieciochesca”.Este objeto de estudio se concreta en la finalidad de “clarificar y exponer la historia del violín en España durante el siglo XVIII”. Adaptándose parcialmente en este artículo al objetivo específico de “estudiar las diferentes vías de transmisión del conocimiento violinístico en España y su aportación pedagógica a la historia universal del violín”. Una investigación que se mueve de forma transversal entre las humanidades y su área de conocimiento musicológico y las ciencias sociales en el área de teoría e historia de la educación. Todo ello visto desde el prisma violinístico, que tanta literatura ha generado para la historia universal pero que no ha sido profusa en nuestras historias nacionales de origen ibérico y latinoamericano, siendo una investigación de un área absolutamente deficitaria y que tanta falta nos hace rescatar, máxime escrita en español.A modo conclusivo, cabe decir que si efectivamente la enseñanza musical a lo largo del siglo XVIII se imparte principalmente en las capillas musicales, existió también un ámbito de enseñanza más civil o privado, así como en las casas nobiliarias que de forma incipiente y hacia finales de siglo se apertura con las academias ilustradas. Igualmente, debemos señalar que si el material pedagógico legado es escaso si lo comparamos con los países a la vanguardia y empleo del instrumento, no deja por ello de ser relevante no solo para el violín sino para la historia de la música instrumental española.
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- 2023
16. Linearity of homogeneous solutions to degenerate elliptic equations in dimension three
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Galvez, Jose A. and Mira, Pablo
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Mathematics - Analysis of PDEs ,Mathematics - Differential Geometry ,35J70, 35R05, 53A05, 53C42 - Abstract
Given a linear elliptic equation $\sum a_{ij} u_{ij} =0$ in $\mathbb{R}^3$, it is a classical problem to determine if its degree-one homogeneous solutions $u$ are linear. The answer is negative in general, by a construction of Martinez-Maure. In contrast, the answer is affirmative in the uniformly elliptic case, by a theorem of Han, Nadirashvili and Yuan, and it is a known open problem to determine the degenerate ellipticity condition on $(a_{ij})$ under which this theorem still holds. In this paper we solve this problem. We prove the linearity of $u$ under the following degenerate ellipticity condition for $(a_{ij})$, which is sharp by Martinez-Maure example: if $\mathcal{K}$ denotes the ratio between the largest and smallest eigenvalues of $(a_{ij})$, we assume $\mathcal{K}|_{\mathcal{O}}$ lies in $L_{\rm loc}^1$ for some connected open set $\mathcal{O}\subset \mathbb{S}^2$ that intersects any configuration of four disjoint closed geodesic arcs of length $\pi$ in $\mathbb{S}^2$. Our results also give the sharpest possible version under which an old conjecture by Alexandrov, Koutroufiotis and Nirenberg (disproved by Martinez-Maure's example) holds., Comment: 21 pages, 7 figures. Minor wording changes with respect to the initial version
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- 2021
17. Static elastic modulus prediction at early ages using a modified resonant test for concrete cylinders using mems microphones
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Lara, Cristóbal A., De la Mora Gálvez, José-Francisco, Cascante, Giovanni, and Pandey, Mahesh D.
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- 2024
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18. A study of all-electric electron spin resonance using Floquet quantum master equations
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Reina-Gálvez, Jose, Lorente, Nicolás, Delgado, Fernando, and Arrachea, Liliana
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Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science - Abstract
We present a theoretical framework to describe experiments directed to controlling single-atom spin dynamics by electrical means using a scanning tunneling microscope. We propose a simple model consisting of a quantum impurity connected to electrodes where an electrical time-dependent bias is applied. We solve the problem in the limit of weak coupling between the impurity and the electrodes by means of a quantum master equation that is derived by the non-equilibrium Green's function formalism. We show results in two cases. The first case is just a single atomic orbital subjected to a time-dependent electric field, and the second case consists of a single atomic orbital coupled to a second spin-1/2. The first case reproduces the main experimental features Ti atoms on MgO/Ag (100) while the second one directly addresses the experiments on two Ti atoms. These calculations permit us to explore the effect of different parameters on the driving of the atomic spins as well as to reproduce experimental fingerprints., Comment: This article is a resubmitted version that will be sent to publish soon
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- 2021
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19. A quasiconformal Hopf soap bubble theorem
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Galvez, Jose A., Mira, Pablo, and Tassi, Marcos P.
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,53A10, 53C42, 35J60 - Abstract
We show that any compact surface of genus zero in Euclidean 3-space that satisfies a quasiconformal inequality between its principal curvatures is a round sphere. This solves an old open problem by H. Hopf, and gives a spherical version of Simon's quasiconformal Bernstein theorem. The result generalizes, among others, Hopf's theorem for constant mean curvature spheres, the classification of round spheres as the only compact elliptic Weingarten surfaces of genus zero, and the uniqueness theorem for ovaloids by Han, Nadirashvili and Yuan. The proof relies on the Bers-Nirenberg representation of solutions to linear elliptic equations with discontinuous coefficients., Comment: 19 pages, 3 figures
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- 2021
20. Quasiconformal Gauss maps and the Bernstein problem for Weingarten multigraphs
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Fernandez, Isabel, Galvez, Jose A., and Mira, Pablo
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,53A10, 53C42, 35J15, 35J60 - Abstract
We prove that any complete, uniformly elliptic Weingarten surface in Euclidean $3$-space whose Gauss map image omits an open hemisphere is a cylinder or a plane. This generalizes a classical theorem by Hoffman, Osserman and Schoen for constant mean curvature surfaces. In particular, this proves that planes are the only complete, uniformly elliptic Weingarten multigraphs. We also show that this result holds for a large class of non-uniformly elliptic Weingarten equations. In particular, this solves in the affirmative the Bernstein problem for entire graphs for that class of elliptic equations. To obtain these results, we prove that planes are the only complete multigraphs with quasiconformal Gauss map and bounded second fundamental form., Comment: 29 pages, 10 figures
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- 2020
21. Metabolomic markers of electrolytes, gases and internal environment of the content of chronic subdural hematomas
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Lacerda-Gallardo, Angel Jesús, Abreu-Pérez, Daisy, de Jesús Mazorra Pazo, Miguel, and Antonio Galvez, Jose
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- 2024
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22. Desert truffle genomes reveal their reproductive modes and new insights into plant–fungal interaction and ectendomycorrhizal lifestyle
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Marqués‐Gálvez, José Eduardo, Miyauchi, Shingo, Paolocci, Francesco, Navarro‐Ródenas, Alfonso, Arenas, Francisco, Pérez‐Gilabert, Manuela, Morin, Emmanuelle, Auer, Lucas, Barry, Kerrie W, Kuo, Alan, Grigoriev, Igor V, Martin, Francis M, Kohler, Annegret, and Morte, Asunción
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Microbiology ,Plant Biology ,Biological Sciences ,Ecology ,Genetics ,Ascomycota ,Cistaceae ,Life Style ,Mycorrhizae ,Reproduction ,Symbiosis ,arid environment ,desert truffles ,drought stress ,ectendomycorrhizal symbiosis ,MAT genes ,mycorrhiza ,plant– ,microbe interactions ,plant-microbe interactions ,Agricultural and Veterinary Sciences ,Plant Biology & Botany ,Plant biology ,Climate change impacts and adaptation ,Ecological applications - Abstract
Desert truffles are edible hypogeous fungi forming ectendomycorrhizal symbiosis with plants of Cistaceae family. Knowledge about the reproductive modes of these fungi and the molecular mechanisms driving the ectendomycorrhizal interaction is lacking. Genomes of the highly appreciated edible desert truffles Terfezia claveryi Chatin and Tirmania nivea Trappe have been sequenced and compared with other Pezizomycetes. Transcriptomes of T. claveryi × Helianthemum almeriense mycorrhiza from well-watered and drought-stressed plants, when intracellular colonizations is promoted, were investigated. We have identified the fungal genes related to sexual reproduction in desert truffles and desert-truffles-specific genomic and secretomic features with respect to other Pezizomycetes, such as the expansion of a large set of gene families with unknown Pfam domains and a number of species or desert-truffle-specific small secreted proteins differentially regulated in symbiosis. A core set of plant genes, including carbohydrate, lipid-metabolism, and defence-related genes, differentially expressed in mycorrhiza under both conditions was found. Our results highlight the singularities of desert truffles with respect to other mycorrhizal fungi while providing a first glimpse on plant and fungal determinants involved in ecto to endo symbiotic switch that occurs in desert truffle under dry conditions.
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- 2021
23. Klangliche Materialität(en) von Musik — Versuch einer So(u)ndierung in den Popular Music Studies. Ein Forum
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Delle, Anne, primary, Fabian, Alan, additional, Gálvez, José, additional, Gilli, Lorenz, additional, Just, Steffen, additional, Klauke, Christopher, additional, and Muchitsch, Veronika, additional
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- 2023
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24. Complete surfaces of constant anisotropic mean curvature
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Gálvez, José A., Mira, Pablo, and Tassi, Marcos P.
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- 2023
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25. Complete surfaces of constant anisotropic mean curvature
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Galvez, Jose A., Mira, Pablo, and Tassi, Marcos P.
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,53A10, 53C42 - Abstract
We study the geometry of complete immersed surfaces in $\mathbb{R}^3$ with constant anisotropic mean curvature (CAMC). Assuming that the anisotropic functional is uniformly elliptic, we prove that: (1) planes and CAMC cylinders are the only complete surfaces with CAMC whose Gauss map image is contained in a closed hemisphere of $\mathbb{S}^2$; (2) Any complete surface with non-zero CAMC and whose Gaussian curvature does not change sign is either a CAMC cylinder or the Wulff shape, up to a homothety of $\mathbb{R}^3$; and (3) if the Wulff shape $W$ of the anisotropic functional is invariant with respect to three linearly independent reflections in $\mathbb{R}^3$, then any properly embedded surface of non-zero CAMC, finite topology and at most one end is homothetic to $W$., Comment: 22 pages, 3 figures
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- 2019
26. Forecasting tropical cyclone rainfall and flooding hazards and impacts
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Lamers, Alex, Devi. S, Sunitha, Sharma, Monica, Berg, Robbie, Gálvez, José Manuel, Yu, Zifeng, Kriat, Tarik, Cardos, Sareti, Grant, David, and Moron, Lorenzo A.
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- 2023
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27. A mycorrhizal helper bacterium alleviates drought stress in mycorrhizal Helianthemum almeriense plants by regulating water relations and plant hormones
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Guarnizo, Ángel Luigi, Navarro-Ródenas, Alfonso, Calvo-Polanco, Mónica, Marqués-Gálvez, José Eduardo, and Morte, Asunción
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- 2023
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28. Stratification strength and light climate explain variation in chlorophyll a at the continental scale in a European multilake survey in a heatwave summer
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Donis, Daphne, Mantzouki, Evanthia, McGinnis, Daniel F., Vachon, Dominic, Gallego, Irene, Grossart, Hans-Peter, de Senerpont Domis, Lisette N., Teurlincx, Sven, Seelen, Laura, Lürling, Miquel, Verstijnen, Yvon, Maliaka, Valentini, Fonvielle, Jeremy, Visser, Petra M., Verspagen, Jolanda, van Herk, Maria, Antoniou, Maria G., Tsiarta, Nikoletta, McCarthy, Valerie, Perello, Victor C., Machado-Vieira, Danielle, de Oliveira, Alinne Gurjão, Maronić, Dubravka Špoljarić, Stević, Filip, Pfeiffer, Tanja Žuna, Vucelić, Itana Bokan, Žutinić, Petar, Udovič, Marija Gligora, Plenković-Moraj, Anđelka, Bláha, Luděk, Geriš, Rodan, Fránková, Markéta, Christoffersen, Kirsten Seestern, Warming, Trine Perlt, Feldmann, Tõnu, Laas, Alo, Panksep, Kristel, Tuvikene, Lea, Kangro, Kersti, Koreivienė, Judita, Karosienė, Jūratė, Kasperovičienė, Jūratė, Savadova-Ratkus, Ksenija, Vitonytė, Irma, Häggqvist, Kerstin, Salmi, Pauliina, Arvola, Lauri, Rothhaupt, Karl, Avagianos, Christos, Kaloudis, Triantafyllos, Gkelis, Spyros, Panou, Manthos, Triantis, Theodoros, Zervou, Sevasti-Kiriaki, Hiskia, Anastasia, Obertegger, Ulrike, Boscaini, Adriano, Flaim, Giovanna, Salmaso, Nico, Cerasino, Leonardo, Haande, Sigrid, Skjelbred, Birger, Grabowska, Magdalena, Karpowicz, Maciej, Chmura, Damian, Nawrocka, Lidia, Kobos, Justyna, Mazur-Marzec, Hanna, Alcaraz-Párraga, Pablo, Wilk-Woźniak, Elżbieta, Krztoń, Wojciech, Walusiak, Edward, Gagala-Borowska, Ilona, Mankiewicz-Boczek, Joana, Toporowska, Magdalena, Pawlik-Skowronska, Barbara, Niedźwiecki, Michał, Pęczuła, Wojciech, Napiórkowska-Krzebietke, Agnieszka, Dunalska, Julita, Sieńska, Justyna, Szymański, Daniel, Kruk, Marek, Budzyńska, Agnieszka, Goldyn, Ryszard, Kozak, Anna, Rosińska, Joanna, Szeląg-Wasielewska, Elżbieta, Domek, Piotr, Jakubowska-Krepska, Natalia, Kwasizur, Kinga, Messyasz, Beata, Pełechata, Aleksandra, Pełechaty, Mariusz, Kokocinski, Mikolaj, Madrecka-Witkowska, Beata, Kostrzewska-Szlakowska, Iwona, Frąk, Magdalena, Bańkowska-Sobczak, Agnieszka, Wasilewicz, Michał, Ochocka, Agnieszka, Pasztaleniec, Agnieszka, Jasser, Iwona, Antão-Geraldes, Ana M., Leira, Manel, Vasconcelos, Vitor, Morais, Joao, Vale, Micaela, Raposeiro, Pedro M., Gonçalves, Vítor, Aleksovski, Boris, Krstić, Svetislav, Nemova, Hana, Drastichova, Iveta, Chomova, Lucia, Remec-Rekar, Spela, Elersek, Tina, Hansson, Lars-Anders, Urrutia-Cordero, Pablo, Bravo, Andrea G., Buck, Moritz, Colom-Montero, William, Mustonen, Kristiina, Pierson, Don, Yang, Yang, Richardson, Jessica, Edwards, Christine, Cromie, Hannah, Delgado-Martín, Jordi, García, David, Cereijo, Jose Luís, Gomà, Joan, Trapote, Mari Carmen, Vegas-Vilarrúbia, Teresa, Obrador, Biel, García-Murcia, Ana, Real, Monserrat, Romans, Elvira, Noguero-Ribes, Jordi, Duque, David Parreño, Fernández-Morán, Elísabeth, Úbeda, Bárbara, Gálvez, José Ángel, Catalán, Núria, Pérez-Martínez, Carmen, Ramos-Rodríguez, Eloísa, Cillero-Castro, Carmen, Moreno-Ostos, Enrique, Blanco, José María, Rodríguez, Valeriano, Montes-Pérez, Jorge Juan, Palomino, Roberto L., Rodríguez-Pérez, Estela, Hernández, Armand, Carballeira, Rafael, Camacho, Antonio, Picazo, Antonio, Rochera, Carlos, Santamans, Anna C., Ferriol, Carmen, Romo, Susana, Soria, Juan Miguel, Özen, Arda, Karan, Tünay, Demir, Nilsun, Beklioğlu, Meryem, Filiz, Nur, Levi, Eti, Iskin, Uğur, Bezirci, Gizem, Tavşanoğlu, Ülkü Nihan, Çelik, Kemal, Ozhan, Koray, Karakaya, Nusret, Koçer, Mehmet Ali Turan, Yilmaz, Mete, Maraşlıoğlu, Faruk, Fakioglu, Özden, Soylu, Elif Neyran, Yağcı, Meral Apaydın, Çınar, Şakir, Çapkın, Kadir, Yağcı, Abdulkadir, Cesur, Mehmet, Bilgin, Fuat, Bulut, Cafer, Uysal, Rahmi, Latife, Köker, Akçaalan, Reyhan, Albay, Meriç, Alp, Mehmet Tahir, Özkan, Korhan, Sevindik, Tuğba Ongun, Tunca, Hatice, Önem, Burçin, Paerl, Hans, Carey, Cayelan C., and Ibelings, Bastiaan W.
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- 2021
29. Rotational hypersurfaces of prescribed mean curvature
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Bueno, Antonio, Galvez, Jose A., and Mira, Pablo
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Mathematics - Differential Geometry ,Mathematics - Classical Analysis and ODEs ,53A10, 53C42, 34C05, 34C40 - Abstract
We use a phase space analysis to give some classification results for rotational hypersurfaces in $\mathbb{R}^{n+1}$ whose mean curvature is given as a prescribed function of its Gauss map. For the case where the prescribed function is an even function in $\mathbb{S}^n$, we show that a Delaunay-type classification holds for this class of hypersurfaces. We also exhibit examples showing that the behavior of rotational hypersurfaces of prescribed (non-constant) mean curvature is much richer than in the constant mean curvature case., Comment: 23 pages, 30 figures. The results of this paper were originally contained in our previous posting arXiv:1802.08146 which, because of its length and following the editor's suggestion, has now been divided into two papers; the present paper is one of them
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- 2019
30. Serrin's overdetermined problem for fully nonlinear non-elliptic equations
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Gálvez, José A. and Mira, Pablo
- Subjects
Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs - Abstract
Let $u$ denote a solution to a rotationally invariant Hessian equation $F(D^2u)=0$ on a bounded simply connected domain $\Omega\subset R^2$, with constant Dirichlet and Neumann data on $\partial \Omega$. In this paper we prove that if $u$ is real analytic and not identically zero, then $u$ is radial and $\Omega$ is a disk. The fully nonlinear operator $F\not\equiv 0$ is of general type, and in particular, not assumed to be elliptic. We also show that the result is sharp, in the sense that it is not true if $\Omega$ is not simply connected, or if $u$ is $C^{\infty}$ but not real analytic.
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- 2019
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31. Ectomycorrhizal Symbiosis: From Genomics to Trans-Kingdom Molecular Communication and Signaling
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Marqués-Gálvez, José Eduardo, Veneault-Fourrey, Claire, Kohler, Annegret, Sharma, Anil Kumar, Series Editor, Horwitz, Benjamin A., editor, and Mukherjee, Prasun K., editor
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- 2022
- Full Text
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32. The enhanced X-ray Timing and Polarimetry mission - eXTP
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Zhang, ShuangNan, Santangelo, Andrea, Feroci, Marco, Xu, YuPeng, Lu, FangJun, Chen, Yong, Feng, Hua, Zhang, Shu, Brandt, Søren, Hernanz, Margarita, Baldini, Luca, Bozzo, Enrico, Campana, Riccardo, De Rosa, Alessandra, Dong, YongWei, Evangelista, Yuri, Karas, Vladimir, Meidinger, Norbert, Meuris, Aline, Nandra, Kirpal, Pan, Teng, Pareschi, Giovanni, Orleanski, Piotr, Huang, QiuShi, Schanne, Stephane, Sironi, Giorgia, Spiga, Daniele, Svoboda, Jiri, Tagliaferri, Gianpiero, Tenzer, Christoph, Vacchi, Andrea, Zane, Silvia, Walton, Dave, Wang, ZhanShan, Winter, Berend, Wu, Xin, Zand, Jean J. M. in 't, Ahangarianabhari, Mahdi, Ambrosi, Giovanni, Ambrosino, Filippo, Barbera, Marco, Basso, Stefano, Bayer, Jörg, Bellazzini, Ronaldo, Bellutti, Pierluigi, Bertucci, Bruna, Bertuccio, Giuseppe, Borghi, Giacomo, Cao, XueLei, Cadoux, Franck, Ceraudo, Francesco, Chen, TianXiang, Chen, YuPeng, Chevenez, Jerome, Civitani, Marta, Cui, Wei, Cui, WeiWei, Dauser, Thomas, Del Monte, Ettore, Di Cosimo, Sergio, Diebold, Sebastian, Doroshenko, Victor, Dovciak, Michal, Du, YuanYuan, Ducci, Lorenzo, Fan, QingMei, Favre, Yannick, Fuschino, Fabio, Gálvez, José Luis, Gao, Min, Ge, MingYu, Gevin, Olivier, Grassi, Marco, Gu, QuanYing, Gu, YuDong, Han, DaWei, Hong, Bin, Hu, Wei, Ji, Long, Jia, ShuMei, Jiang, WeiChun, Kennedy, Thomas, Kreykenbohm, Ingo, Kuvvetli, Irfan, Labanti, Claudio, Latronico, Luca, Li, Gang, Li, MaoShun, Li, Xian, Li, Wei, Li, ZhengWei, Limousin, Olivier, Liu, HongWei, Liu, XiaoJing, Lu, Bo, Luo, Tao, Macera, Daniele, Malcovati, Piero, Martindale, Adrian, Michalska, Malgorzata, Meng, Bin, Minuti, Massimo, Morbidini, Alfredo, Muleri, Fabio, Paltani, Stephane, Perinati, Emanuele, Picciotto, Antonino, Piemonte, Claudio, Qu, JinLu, Rachevski, Alexandre, Rashevskaya, Irina, Rodriguez, Jerome, Schanz, Thomas, Shen, ZhengXiang, Sheng, LiZhi, Song, JiangBo, Song, LiMing, Sgro, Carmelo, Sun, Liang, Tan, Ying, Uttley, Phil, Wang, Juan, Wang, LangPing, Wang, YuSa, Watts, Anna L., Wen, XiangYang, Wilms, Jörn, Xiong, ShaoLin, Yang, JiaWei, Yang, Sheng, Yang, YanJi, Yu, Nian, Zhang, WenDa, Zampa, Gianluigi, Zampa, Nicola, Zdziarski, Andrzej A., Zhang, AiMei, Zhang, ChengMo, Zhang, Fan, Zhang, Long, Zhang, Tong, Zhang, Yi, Zhang, XiaoLi, Zhang, ZiLiang, Zhao, BaoSheng, Zheng, ShiJie, Zhou, YuPeng, Zorzi, Nicola, and Zwart, J. Frans
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
In this paper we present the enhanced X-ray Timing and Polarimetry mission - eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources. The paper provides a detailed description of: (1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload; (2) the elements and functions of the mission, from the spacecraft to the ground segment., Comment: Accepted for publication on Sci. China Phys. Mech. Astron. (2019)
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- 2018
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33. Rotational symmetry of Weingarten spheres in homogeneous three-manifolds
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Galvez, Jose A. and Mira, Pablo
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,53A10, 53C42, 49Q05 - Abstract
Let $M$ be a simply connected homogeneous three-manifold with isometry group of dimension $4$, and let $\Sigma$ be any compact surface of genus zero immersed in $M$ whose mean, extrinsic and Gauss curvatures satisfy a smooth elliptic relation $\Phi(H,K_e,K)=0$. In this paper we prove that $\Sigma$ is a sphere of revolution, provided that the unique inextendible rotational surface $S$ in $M$ that satisfies this equation and touches its rotation axis orthogonally has bounded second fundamental form. In particular, we prove that: (i) any elliptic Weingarten sphere immersed in $\mathbb{H}^2\times \mathbb{R}$ is a rotational sphere. (ii) Any sphere of constant positive extrinsic curvature immersed in $M$ is a rotational sphere, and (iii) Any immersed sphere in $M$ that satisfies an elliptic Weingarten equation $H=\phi(H^2-K_e)\geq a>0$ with $\phi$ bounded, is a rotational sphere. As a very particular case of this last result, we recover the Abresch-Rosenberg classification of constant mean curvature spheres in $M$., Comment: 43 pages
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- 2018
34. The global geometry of surfaces with prescribed mean curvature in $\mathbb{R}^3$
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Bueno, Antonio, Galvez, Jose A., and Mira, Pablo
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Mathematics - Differential Geometry ,53A10, 53C42 - Abstract
We develop a global theory for complete hypersurfaces in $\mathbb{R}^{n+1}$ whose mean curvature is given as a prescribed function of its Gauss map. This theory extends the usual one of constant mean curvature hypersurfaces in $\mathbb{R}^{n+1}$, and also that of self-translating solitons of the mean curvature flow. For the particular case $n=2$, we will obtain results regarding a priori height and curvature estimates, non-existence of complete stable surfaces, and classification of properly embedded surfaces with at most one end., Comment: 35 pages. We have substantially shortened the paper with respect to version 1, following the editor's suggestion
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- 2018
35. Isolated singularities of the prescribed mean curvature equation in Minkowski $3$-space
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Gálvez, José A., Jiménez, Asun, and Mira, Pablo
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Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,35J62, 53C42 - Abstract
We give a classification of non-removable isolated singularities for real analytic solutions of the prescribed mean curvature equation in Minkowski $3$-space.
- Published
- 2017
36. Normativität ohne Normen – Geschichte ohne Vergangenheit : Ästhetische Paradoxa populärer Musik
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Gálvez, José and Schwarz, Marina, editor
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- 2021
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37. Desert Truffles (Terfezia spp.) Breeding
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Morte, Asunción, Arenas, Francisco, Marqués-Gálvez, José E., Andrino, Alberto, Guarnizo, Ángel L., Gutiérrez, Almudena, Berná, Luis Miguel, Pérez-Gilabert, Manuela, Rodríguez, Antonio, Navarro-Ródenas, Alfonso, Al-Khayri, Jameel M., editor, Jain, S. Mohan, editor, and Johnson, Dennis V., editor
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- 2021
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38. Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability
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Mahía, Alejandro, Peña-Díaz, Samuel, Navarro, Susanna, José Galano-Frutos, Juan, Pallarés, Irantzu, Pujols, Jordi, Díaz-de-Villegas, María D., Gálvez, José A., Ventura, Salvador, and Sancho, Javier
- Published
- 2021
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39. What supports the deep chlorophyll maximum in acidic lakes? The role of the bacterial CO₂ production in the hypolimnion
- Author
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Soria-Píriz, Sara, Lara, Miguel, Jiménez-Arias, Juan Luis, Papaspyrou, Sokratis, Úbeda, Bárbara, García-Robledo, Emilio, Bohórquez, Julio, Gálvez, José Ángel, Revsbech, Niels Peter, and Corzo, Alfonso
- Published
- 2020
40. Uniqueness of immersed spheres in three-manifolds
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Galvez, Jose A. and Mira, Pablo
- Subjects
Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,53A10 - Abstract
Let $\mathcal{A}$ be a class of immersed surfaces in a three-manifold $M$, and assume that $\mathcal{A}$ is modeled by an elliptic PDE over each tangent plane. In this paper we solve the so-called Hopf uniqueness problem for the class $\mathcal{A}$ under the only mild assumption of the existence of a transitive family of candidate surfaces $\mathcal{S}\subset \mathcal{A}$. Specifically, we prove that any compact immersed surface of genus zero in the class $\mathcal{A}$ is a candidate sphere. This theorem unifies and extends many previous uniqueness results of different contexts. As an application, we settle in the affirmative a 1956 conjecture by A.D. Alexandrov on the uniqueness of immersed spheres with prescribed curvatures in $\mathbb{R}^3$., Comment: 13 pages, 1 figure
- Published
- 2016
41. El violín ibérico en el siglo de las luces: Una encrucijada marcada por una disputa estética
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Gil de Gálvez, José Manuel and Picazo Gutiérrez, Marina
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Violin ,instrumental music ,eighteenth century ,Spain ,Corominas ,Corelli. - Abstract
This article addresses the development of the violin in eighteenth-century Spain from an esthetic point of view. This was a complex history, full of nuances and dramatic turns, until the instrument finally opened up to the Italian way. First we analyze its Iberian background in parallel with contemporaneous developments in other countries. Likewise, we analyze the reasons for the slow acceptance of purely instrumental music and the continued use of the instrument in Church services. These discussions are based on aesthetic controversies between theorists, composers and instrumentalists. We consider in more detail, the Aposento Anticrítico, by Francisco Corominas, as an aesthetic reference book in the defense of the use of the violin in the cathedrals and churches of eighteenth-century Spanish. Parallel to this, we engage on a discursive controversy emanating from the contrariety of underestimating the instrument, and in turn, accepting the music of Corelli and the Italian masters. An aesthetic diatribe that persists in the Iberian Peninsula until the end of the century of lights.
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- 2018
42. Entire solutions of the degenerateMonge-Ampere equation with a finite number of singularities
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Galvez, Jose' Antonio and Nelli, Barbara
- Subjects
Mathematics - Differential Geometry ,Mathematics - Analysis of PDEs ,35K10, 53C21, 53A05 - Abstract
We determine the global behavior of every C^2-solution to the two-dimensional degenerate Monge-Ampere equation, u_{xx}u_{yy}-u_{xy}^2=0, over the finitely punctured plane. With this, we classify every solution in the once or twice punctured plane. Moreover, when we have more than two singularities, if the solution u is not linear in a half-strip, we obtain that the singularities are placed at the vertices of a convex polyhedron P and the graph of u is made by pieces of cones outside of P which are suitably glued along the sides of the polyhedron. Finally, if we look for analytic solutions, then there is at most one singularity and the graph of $u$ is either a cylinder (no singularity) or a cone (one singularity)., Comment: 20 pages, 10 figures
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- 2016
43. A Hopf theorem for non-constant mean curvature and a conjecture of A.D. Alexandrov
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Galvez, Jose A. and Mira, Pablo
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Mathematics - Differential Geometry ,53A10, 49Q05, 53C42 - Abstract
We prove a uniqueness theorem for immersed spheres of prescribed (non-constant) mean curvature in homogeneous three-manifolds. In particular, this uniqueness theorem proves a conjecture by A.D. Alexandrov about immersed spheres of prescribed Weingarten curvature in R3 for the special but important case of prescribed mean curvature. As a consequence, we extend the classical Hopf uniqueness theorem for constant mean curvature spheres to the case of immersed spheres of prescribed antipodally symmetric mean curvature in R3., Comment: 14 pages
- Published
- 2015
44. Ectomycorrhizal Symbiosis: From Genomics to Trans-Kingdom Molecular Communication and Signaling
- Author
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Marqués-Gálvez, José Eduardo, primary, Veneault-Fourrey, Claire, additional, and Kohler, Annegret, additional
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- 2022
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45. An inshore–offshore sorting system revealed from global classification of ocean litter
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Morales-Caselles, Carmen, Viejo, Josué, Martí, Elisa, González-Fernández, Daniel, Pragnell-Raasch, Hannah, González-Gordillo, J. Ignacio, Montero, Enrique, Arroyo, Gonzalo M., Hanke, Georg, Salvo, Vanessa S., Basurko, Oihane C., Mallos, Nicholas, Lebreton, Laurent, Echevarría, Fidel, van Emmerik, Tim, Duarte, Carlos M., Gálvez, José A., van Sebille, Erik, Galgani, François, García, Carlos M., Ross, Peter S., Bartual, Ana, Ioakeimidis, Christos, Markalain, Gorka, Isobe, Atsuhiko, and Cózar, Andrés
- Published
- 2021
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46. Genomic analysis defines distinct pancreatic and neuronal subtypes of lung carcinoid.
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Domingo‐Sabugo, Clara, Willis‐Owen, Saffron AG, Mandal, Amit, Nastase, Anca, Dwyer, Sarah, Brambilla, Cecilia, Gálvez, José Héctor, Zhuang, Qinwei, Popat, Sanjay, Eveleigh, Robert, Munter, Markus, Lim, Eric, Nicholson, Andrew G, Lathrop, G Mark, Cookson, William OC, and Moffatt, Miriam F
- Subjects
GENETIC load ,NEUROENDOCRINE tumors ,SINGLE nucleotide polymorphisms ,APOLIPOPROTEIN B ,GENOMICS ,CARCINOID - Abstract
Lung carcinoids (L‐CDs) are rare, poorly characterised neuroendocrine tumours (NETs). L‐CDs are more common in women and are not the consequence of cigarette smoking. They are classified histologically as typical carcinoids (TCs) or atypical carcinoids (ACs). ACs confer a worse survival. Histological classification is imperfect, and there is increasing interest in molecular markers. We therefore investigated global transcriptomic and epigenomic profiles of 15 L‐CDs resected with curative intent at Royal Brompton Hospital. We identified underlying mutations and structural abnormalities through whole‐exome sequencing (WES) and single nucleotide polymorphism (SNP) genotyping. Transcriptomic clustering algorithms identified two distinct L‐CD subtypes. These showed similarities either to pancreatic or neuroendocrine tumours at other sites and so were named respectively L‐CD‐PanC and L‐CD‐NeU. L‐CD‐PanC tumours featured upregulation of pancreatic and metabolic pathway genes matched by promoter hypomethylation of genes for beta cells and insulin secretion (p < 1 × 10−6). These tumours were centrally located and showed mutational signatures of activation‐induced deaminase/apolipoprotein B editing complex activity, together with genome‐wide DNA methylation loss enriched in repetitive elements (p = 2.2 × 10−16). By contrast, the L‐CD‐NeU group exhibited upregulation of neuronal markers (adjusted p < 0.01) and was characterised by focal spindle cell morphology (p = 0.04), peripheral location (p = 0.01), high mutational load (p = 2.17 × 10−4), recurrent copy number alterations, and enrichment for ACs. Mutations affected chromatin remodelling and SWI/SNF complex pathways. L‐CD‐NeU tumours carried a mutational signature attributable to aflatoxin and aristolochic acid (p = 0.05), suggesting a possible environmental exposure in their pathogenesis. Immunologically, myeloid and T‐cell markers were enriched in L‐CD‐PanC and B‐cell markers in L‐CD‐NeU tumours. The substantial epigenetic and non‐coding differences between L‐CD‐PanC and L‐CD‐NeU open new possibilities for biomarker selection and targeted treatment of L‐CD. © 2024 The Author(s). The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland. [ABSTRACT FROM AUTHOR]
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- 2024
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47. A quasiconformal Hopf soap bubble theorem
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Gálvez, José A., Mira, Pablo, and Tassi, Marcos P.
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- 2022
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48. Vascular Reactivity Profile of Novel KCa3.1‐Selective Positive‐Gating Modulators in the Coronary Vascular Bed
- Author
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Oliván-Viguera, Aida, Valero, Marta Sofía, Pinilla, Estéfano, Amor, Sara, García-Villalón, Ángel Luis, Coleman, Nichole, Laría, Celia, Calvín-Tienza, Víctor, García-Otín, Ángel-Luis, Fernández-Fernández, José M, Murillo, M Divina, Gálvez, José A, Díaz-de-Villegas, María D, Badorrey, Ramón, Simonsen, Ulf, Rivera, Luis, Wulff, Heike, and Köhler, Ralf
- Subjects
Medical Physiology ,Biomedical and Clinical Sciences ,Cardiovascular ,Heart Disease - Coronary Heart Disease ,Heart Disease ,1.1 Normal biological development and functioning ,Animals ,Bradykinin ,Cells ,Cultured ,Coronary Circulation ,Coronary Vessels ,Endothelial Cells ,Endothelium ,Vascular ,Gene Expression Regulation ,Heart ,Intermediate-Conductance Calcium-Activated Potassium Channels ,Male ,Nitric Oxide Synthase Type III ,Oxazoles ,Patch-Clamp Techniques ,Pyrazoles ,RNA ,Messenger ,Rats ,Rats ,Sprague-Dawley ,Swine ,Vasodilation ,Vasodilator Agents ,Pharmacology and Pharmaceutical Sciences ,Pharmacology & Pharmacy ,Pharmacology and pharmaceutical sciences - Abstract
Opening of intermediate-conductance calcium-activated potassium channels (KC a 3.1) produces membrane hyperpolarization in the vascular endothelium. Here, we studied the ability of two new KC a 3.1-selective positive-gating modulators, SKA-111 and SKA-121, to (1) evoke porcine endothelial cell KC a 3.1 membrane hyperpolarization, (2) induce endothelium-dependent and, particularly, endothelium-derived hyperpolarization (EDH)-type relaxation in porcine coronary arteries (PCA) and (3) influence coronary artery tone in isolated rat hearts. In whole-cell patch-clamp experiments on endothelial cells of PCA (PCAEC), KC a currents evoked by bradykinin (BK) were potentiated ≈7-fold by either SKA-111 or SKA-121 (both at 1 μM) and were blocked by a KC a 3.1 blocker, TRAM-34. In membrane potential measurements, SKA-111 and SKA-121 augmented bradykinin-induced hyperpolarization. Isometric tension measurements in large- and small-calibre PCA showed that SKA-111 and SKA-121 potentiated endothelium-dependent relaxation with intact NO synthesis and EDH-type relaxation to BK by ≈2-fold. Potentiation of the BK response was prevented by KC a 3.1 inhibition. In Langendorff-perfused rat hearts, SKA-111 potentiated coronary vasodilation elicited by BK. In conclusion, our data show that positive-gating modulation of KC a 3.1 channels improves BK-induced membrane hyperpolarization and endothelium-dependent relaxation in small and large PCA as well as in the coronary circulation of rats. Positive-gating modulators of KC a 3.1 could be therapeutically useful to improve coronary blood flow and counteract impaired coronary endothelial dysfunction in cardiovascular disease.
- Published
- 2016
49. Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
- Author
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Oliván-Viguera, Aida, Valero, Marta Sofía, Pinilla, Estéfano, Amor, Sara, García-Villalón, Ángel Luis, Coleman, Nichole, Laría, Celia, Calvín-Tienza, Víctor, García-Otín, Ángel-Luis, Fernández-Fernández, José M, Murillo, M Divina, Gálvez, José A, Díaz-de-Villegas, María D, Badorrey, Ramón, Simonsen, Ulf, Rivera, Luis, Wulff, Heike, and Köhler, Ralf
- Subjects
Coronary Vessels ,Endothelium ,Vascular ,Heart ,Cells ,Cultured ,Endothelial Cells ,Animals ,Swine ,Rats ,Rats ,Sprague-Dawley ,Oxazoles ,Pyrazoles ,Bradykinin ,RNA ,Messenger ,Vasodilator Agents ,Patch-Clamp Techniques ,Gene Expression Regulation ,Coronary Circulation ,Vasodilation ,Male ,Intermediate-Conductance Calcium-Activated Potassium Channels ,Nitric Oxide Synthase Type III ,Pharmacology & Pharmacy ,Pharmacology and Pharmaceutical Sciences - Abstract
Opening of intermediate-conductance calcium-activated potassium channels (KC a 3.1) produces membrane hyperpolarization in the vascular endothelium. Here, we studied the ability of two new KC a 3.1-selective positive-gating modulators, SKA-111 and SKA-121, to (1) evoke porcine endothelial cell KC a 3.1 membrane hyperpolarization, (2) induce endothelium-dependent and, particularly, endothelium-derived hyperpolarization (EDH)-type relaxation in porcine coronary arteries (PCA) and (3) influence coronary artery tone in isolated rat hearts. In whole-cell patch-clamp experiments on endothelial cells of PCA (PCAEC), KC a currents evoked by bradykinin (BK) were potentiated ≈7-fold by either SKA-111 or SKA-121 (both at 1 μM) and were blocked by a KC a 3.1 blocker, TRAM-34. In membrane potential measurements, SKA-111 and SKA-121 augmented bradykinin-induced hyperpolarization. Isometric tension measurements in large- and small-calibre PCA showed that SKA-111 and SKA-121 potentiated endothelium-dependent relaxation with intact NO synthesis and EDH-type relaxation to BK by ≈2-fold. Potentiation of the BK response was prevented by KC a 3.1 inhibition. In Langendorff-perfused rat hearts, SKA-111 potentiated coronary vasodilation elicited by BK. In conclusion, our data show that positive-gating modulation of KC a 3.1 channels improves BK-induced membrane hyperpolarization and endothelium-dependent relaxation in small and large PCA as well as in the coronary circulation of rats. Positive-gating modulators of KC a 3.1 could be therapeutically useful to improve coronary blood flow and counteract impaired coronary endothelial dysfunction in cardiovascular disease.
- Published
- 2016
50. Isolated singularities of graphs in warped products and Monge-Amp\`ere equations
- Author
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Gálvez, José A., Jiménez, Asun, and Mira, Pablo
- Subjects
Mathematics - Differential Geometry ,35J96, 53C42 - Abstract
We study graphs of positive extrinsic curvature with a non-removable isolated singularity in 3-dimensional warped product spaces, and describe their behavior at the singularity in several natural situations. We use Monge-Amp\`ere equations to give a classification of the surfaces in 3-dimensional space forms which are embedded around a non-removable isolated singularity and have a prescribed, real analytic, positive extrinsic curvature function at every point. Specifically, we prove that this space is in one-to-one correspondence with the space of regular, analytic, strictly convex Jordan curves in the 2-dimensional sphere $\mathbb{S^2}$.
- Published
- 2014
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