25 results on '"Furlong, Michael T."'
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2. Generic Peptide Strategies for LC-MS/MS Bioanalysis of Human Monoclonal Antibody Drugs and Drug Candidates
3. An exploratory universal LC–MS/MS assay for bioanalysis of hinge region-stabilized human IgG4 mAbs in clinical studies
4. Dual universal peptide approach to bioanalysis of human monoclonal antibody protein drug candidates in animal studies
5. A validated enantioselective LC–MS/MS assay for the simultaneous determination of carvedilol and its pharmacologically active 4′-hydroxyphenyl metabolite in human plasma: Application to a clinical pharmacokinetic study
6. A validated LC–MS/MS assay for the simultaneous determination of the anti-leukemic agent dasatinib and two pharmacologically active metabolites in human plasma: Application to a clinical pharmacokinetic study
7. Pellet digestion: a simple and efficient sample preparation technique for LC–MS/MS quantification of large therapeutic proteins in plasma
8. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
9. Evidence for the Colonic Origin of Ovarian Cancer Cell Line SW626
10. Rare Activation of the TCF/β-Catenin Pathway in Ovarian Cancer
11. A validated HPLC–MS/MS assay for quantifying unstable pharmacologically active metabolites of clopidogrel in human plasma: Application to a clinical pharmacokinetic study
12. Innovative Use of LC-MS/MS for Simultaneous Quantitation of Neutralizing Antibody, Residual Drug, and Human Immunoglobulin G in Immunogenicity Assay Development
13. A universal surrogate peptide to enable LC‐MS/MS bioanalysis of a diversity of human monoclonal antibody and human Fc‐fusion protein drug candidates in pre‐clinical animal studies
14. Identifying and overcoming bioanalytical challenges associated with chlorine-containing dehydrogenation metabolites
15. Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
16. Accuracy and predictability of intraocular lens power calculation after photorefractive keratectomy
17. Innovative Use of LC-MS/MS for Simultaneous Quantitation of Neutralizing Antibody, Residual Drug, and Human Immunoglobulin G in Immunogenicity Assay Development.
18. Phosphorylation- and Activation-independent Association of the Tyrosine Kinase Syk and the Tyrosine Kinase Substrates Cbl and Vav with Tubulin in B-Cells
19. Incidence and management of intraoperative and early postoperative complications in 1000 consecutive laser in situ keratomileusis cases
20. Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk
21. Syk, Activated by Cross-linking the B-cell Antigen Receptor, Localizes to the Cytosol Where It Interacts with and Phosphorylates α-Tubulin on Tyrosine
22. Preparation and reactions of zinc and copper organometallics bearing acidic hydrogens
23. Approach to Animated Anthracyclines via an Intramolecular Marschalk Reaction
24. The γ-Secretase Modulator, BMS-932481, Modulates Aβ Peptides in the Plasma and Cerebrospinal Fluid of Healthy Volunteers.
25. Quantitative interference by cysteine and N-acetylcysteine metabolites during the LC-MS/MS bioanalysis of a small molecule.
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