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Your search keyword '"Furberg, C D"' showing total 361 results
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361 results on '"Furberg, C D"'

5. Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten-country panel

Author

BARTER, P. J., BALLANTYNE, C. M., CARMENA, R., CABEZAS, M. CASTRO, CHAPMAN, M. JOHN, COUTURE, P., DE GRAAF, J., DURRINGTON, P. N., FAERGEMAN, O., FROHLICH, J., FURBERG, C. D., GAGNE, C., HAFFNER, S. M., HUMPHRIES, S. E., JUNGNER, I., KRAUSS, R. M., KWITEROVICH, P., MARCOVINA, S., PACKARD, C. J., PEARSON, T. A., REDDY, K. SRINATH, ROSENSON, R., SARRAFZADEGAN, N., SNIDERMAN, A. D., STALENHOEF, A. F., STEIN, E., TALMUD, P. J., TONKIN, A. M., WALLDIUS, G., and WILLIAMS, K. M. S.

Published
2006

21. Antihypertensive Drug Therapies and the Risk of Ischemic Stroke

Author

Klungel, O H, Heckbert, S R, Longstreth, W T, Furberg, C D, Kaplan, R C, Smith, N L, Lemaitre, R N, Leufkens, H G, de Boer, A, Psaty, B M, Dep Farmaceutische wetenschappen, Sub Pharmacotherapy, Theoretical, and Sub Pharmacoepidemiology

Subjects
Adult, Male, Sodium Chloride Symporter Inhibitors, Adrenergic beta-Antagonists, Angiotensin-Converting Enzyme Inhibitors, Middle Aged, Benzothiadiazines, Calcium Channel Blockers, Brain Ischemia, Risk Factors, Case-Control Studies, Hypertension, Humans, Female, Diuretics, Antihypertensive Agents, Aged
Abstract

BACKGROUND: The relative effectiveness of various antihypertensive drugs with regard to the reduction of stroke incidence remains uncertain. OBJECTIVE: To assess the association between first ischemic stroke and use of antihypertensive drugs. METHODS: A population-based case-control study was performed among enrollees of the Group Health Cooperative of Puget Sound. Case patients included pharmacologically treated hypertensive patients who sustained a first ischemic stroke (fatal or nonfatal; n = 380) between July 1, 1989, and December 31, 1996. Control subjects were a random sample of treated hypertensive enrollees without a history of a stroke (n = 2790). Medical record review and a telephone interview of consenting survivors were used to collect information on risk factors for stroke. Computerized pharmacy records were used to assess antihypertensive drug use. RESULTS: Among 1237 single-drug users with no history of cardiovascular disease, the adjusted risk of ischemic stroke was higher among users of a beta-blocker (risk ratio [RR], 2.03; 95% confidence interval [CI], 1.05-3.94), calcium channel blocker (RR, 2.30; 95% CI, 1.16-4.56), or angiotensin-converting enzyme inhibitor (RR, 2.79; 95% CI, 1.47-5. 27) than among users of a thiazide diuretic alone. Among 673 single-drug users with a history of cardiovascular disease, the RRs were 1.22 (95% CI, 0.63-2.35), 1.18 (95% CI, 0.59-2.33), and 1.45 (95% CI, 0.70-3.02) among users of a beta-blocker, calcium channel blocker, and angiotensin-converting enzyme inhibitor, respectively, compared with users of a thiazide diuretic alone. CONCLUSIONS: In this study of pharmacologically treated hypertensive patients, antihypertensive drug regimens that did not include a thiazide diuretic were associated with an increased risk of ischemic stroke compared with regimens that did include a thiazide. These results support the use of thiazide diuretics as first-line antihypertensive agents.

Published
2001

27. Authors' response

Author

Singh, S., primary, Loke, Y. K., additional, Spangler, J. G., additional, and Furberg, C. D., additional

Published
2011
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33. Myocardial infarction and stroke associated with diuretic based two drug antihypertensive regimens: population based case-control study

Author

Boger-Megiddo, I., primary, Heckbert, S. R, additional, Weiss, N. S, additional, McKnight, B., additional, Furberg, C. D, additional, Wiggins, K. L, additional, Delaney, J. A C, additional, Siscovick, D. S, additional, Larson, E. B, additional, Lemaitre, R. N, additional, Smith, N. L, additional, Rice, K. M, additional, Glazer, N. L, additional, and Psaty, B. M, additional

Published
2010
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38. Antihypertensive Drug Therapies and the Risk of Ischemic Stroke

Author

Dep Farmaceutische wetenschappen, Sub Pharmacotherapy, Theoretical, Sub Pharmacoepidemiology, Klungel, O H, Heckbert, S R, Longstreth, W T, Furberg, C D, Kaplan, R C, Smith, N L, Lemaitre, R N, Leufkens, H G, de Boer, A, Psaty, B M, Dep Farmaceutische wetenschappen, Sub Pharmacotherapy, Theoretical, Sub Pharmacoepidemiology, Klungel, O H, Heckbert, S R, Longstreth, W T, Furberg, C D, Kaplan, R C, Smith, N L, Lemaitre, R N, Leufkens, H G, de Boer, A, and Psaty, B M

Published
2001

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