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1. Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

Author

deCamp, Allan C., Corcoran, Martin M., Fulp, William J., Willis, Jordan R., Cottrell, Christopher A., Bader, Daniel L. V., Kalyuzhniy, Oleksandr, Leggat, David J., Cohen, Kristen W., Hyrien, Ollivier, Menis, Sergey, Finak, Greg, Ballweber-Fleming, Lamar, Srikanth, Abhinaya, Plyler, Jason R., Rahaman, Farhad, Lombardo, Angela, Philiponis, Vincent, Whaley, Rachael E., Seese, Aaron, Brand, Joshua, Ruppel, Alexis M., Hoyland, Wesley, Mahoney, Celia R., Cagigi, Alberto, Taylor, Alison, Brown, David M., Ambrozak, David R., Sincomb, Troy, Mullen, Tina-Marie, Maenza, Janine, Kolokythas, Orpheus, Khati, Nadia, Bethony, Jeffrey, Roederer, Mario, Diemert, David, Koup, Richard A., Laufer, Dagna S., McElrath, Juliana M., McDermott, Adrian B., Karlsson Hedestam, Gunilla B., and Schief, William R.

Published
2024
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7. A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study

Author

Scott, Jacob G, Berglund, Anders, Schell, Michael J, Mihaylov, Ivaylo, Fulp, William J, Yue, Binglin, Welsh, Eric, Caudell, Jimmy J, Ahmed, Kamran, Strom, Tobin S, Mellon, Eric, Venkat, Puja, Johnstone, Peter, Foekens, John, Lee, Jae, Moros, Eduardo, Dalton, William S, Eschrich, Steven A, McLeod, Howard, Harrison, Louis B, and Torres-Roca, Javier F

Published
2017
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8. A first-in-human germline-targeting HIV nanoparticle vaccine induced broad and publicly targeted helper T cell responses

Author

Cohen, Kristen W., primary, De Rosa, Stephen C., additional, Fulp, William J., additional, deCamp, Allan C., additional, Fiore-Gartland, Andrew, additional, Mahoney, Celia R., additional, Furth, Sarah, additional, Donahue, Josh, additional, Whaley, Rachael E., additional, Ballweber-Fleming, Lamar, additional, Seese, Aaron, additional, Schwedhelm, Katharine, additional, Geraghty, Daniel, additional, Finak, Greg, additional, Menis, Sergey, additional, Leggat, David J., additional, Rahaman, Farhad, additional, Lombardo, Angela, additional, Borate, Bhavesh R., additional, Philiponis, Vincent, additional, Maenza, Janine, additional, Diemert, David, additional, Kolokythas, Orpheus, additional, Khati, Nadia, additional, Bethony, Jeffrey, additional, Hyrien, Ollivier, additional, Laufer, Dagna S., additional, Koup, Richard A., additional, McDermott, Adrian B., additional, Schief, William R., additional, and McElrath, M. Juliana, additional

Published
2023
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9. Supplementary Table S1 from Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas

Author

Permuth-Wey, Jennifer, primary, Chen, Dung-Tsa, primary, Fulp, William J., primary, Yoder, Sean J., primary, Zhang, Yonghong, primary, Georgeades, Christina, primary, Husain, Kazim, primary, Centeno, Barbara Ann, primary, Magliocco, Anthony M., primary, Coppola, Domenico, primary, and Malafa, Mokenge, primary

Published
2023
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11. Supplementary Figure S3 from Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas

Author

Permuth-Wey, Jennifer, primary, Chen, Dung-Tsa, primary, Fulp, William J., primary, Yoder, Sean J., primary, Zhang, Yonghong, primary, Georgeades, Christina, primary, Husain, Kazim, primary, Centeno, Barbara Ann, primary, Magliocco, Anthony M., primary, Coppola, Domenico, primary, and Malafa, Mokenge, primary

Published
2023
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12. Supplementary Figure Legends from Plasma MicroRNAs as Novel Biomarkers for Patients with Intraductal Papillary Mucinous Neoplasms of the Pancreas

Author

Permuth-Wey, Jennifer, primary, Chen, Dung-Tsa, primary, Fulp, William J., primary, Yoder, Sean J., primary, Zhang, Yonghong, primary, Georgeades, Christina, primary, Husain, Kazim, primary, Centeno, Barbara Ann, primary, Magliocco, Anthony M., primary, Coppola, Domenico, primary, and Malafa, Mokenge, primary

Published
2023
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13. Data from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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15. Supplementary Figure 1 from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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16. Supplementary Table 2 from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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17. Supplementary Methods from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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20. Supplementary Table 1 from Racial Differences in the Incidence and Clearance of Human Papilloma Virus (HPV): The HPV in Men (HIM) Study

Author

Schabath, Matthew B., primary, Villa, Luisa L., primary, Lin, Hui-Yi, primary, Fulp, William J., primary, Akogbe, Gabriel O., primary, Abrahamsen, Martha E., primary, Papenfuss, Mary R., primary, Lazcano-Ponce, Eduardo, primary, Salmerón, Jorge, primary, Quiterio, Manuel, primary, and Giuliano, Anna R., primary

Published
2023
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21. Supplementary Table 1 from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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22. Supplementary Table 3 from BAD Phosphorylation Determines Ovarian Cancer Chemosensitivity and Patient Survival

Author

Marchion, Douglas C., primary, Cottrill, Hope M., primary, Xiong, Yin, primary, Chen, Ning, primary, Bicaku, Elona, primary, Fulp, William J., primary, Bansal, Nisha, primary, Chon, Hye Sook, primary, Stickles, Xiaomang B., primary, Kamath, Siddharth G., primary, Hakam, Ardeshir, primary, Li, Lihua, primary, Su, Dan, primary, Moreno, Carolina, primary, Judson, Patricia L., primary, Berchuck, Andrew, primary, Wenham, Robert M., primary, Apte, Sachin M., primary, Gonzalez-Bosquet, Jesus, primary, Bloom, Gregory C., primary, Eschrich, Steven A., primary, Sebti, Said, primary, Chen, Dung-Tsa, primary, and Lancaster, Johnathan M., primary

Published
2023
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25. Human immunoglobulin gene allelic variation impacts germline-targeting vaccine priming

Author

deCamp, Allan C., Corcoran, Martin M., Fulp, William J., Willis, Jordan R., Cottrell, Christopher A., Bader, Daniel L.V., Kalyuzhniy, Oleksandr, Leggat, David J., Cohen, Kristen W., Hyrien, Ollivier, Menis, Sergey, Finak, Greg, Ballweber-Fleming, Lamar, Srikanth, Abhinaya, Plyler, Jason R., Rahaman, Farhad, Lombardo, Angela, Philiponis, Vincent, Whaley, Rachael E., Seese, Aaron, Brand, Joshua, Ruppel, Alexis M., Hoyland, Wesley, Mahoney, Celia R., Cagigi, Alberto, Taylor, Alison, Brown, David M., Ambrozak, David R., Sincomb, Troy, Mullen, Tina-Marie, Maenza, Janine, Kolokythas, Orpheus, Khati, Nadia, Bethony, Jeffrey, Roederer, Mario, Diemert, David, Koup, Richard A., Laufer, Dagna S., McElrath, Juliana M., McDermott, Adrian B., Hedestam, Gunilla B. Karlsson, and Schief, William R.

Subjects
Article
Abstract

Vaccine priming immunogens that activate germline precursors for broadly neutralizing antibodies (bnAbs) have promise for development of precision vaccines against major human pathogens. In a clinical trial of the eOD-GT8 60mer germline-targeting immunogen, higher frequencies of vaccine-induced VRC01-class bnAb-precursor B cells were observed in the high dose compared to the low dose group. Through immunoglobulin heavy chain variable (IGHV) genotyping, statistical modeling, quantification of IGHV1-2 allele usage and B cell frequencies in the naive repertoire for each trial participant, and antibody affinity analyses, we found that the difference between dose groups in VRC01-class response frequency was best explained by IGHV1-2 genotype rather than dose and was most likely due to differences in IGHV1-2 B cell frequencies for different genotypes. The results demonstrate the need to define population-level immunoglobulin allelic variations when designing germline-targeting immunogens and evaluating them in clinical trials.One-Sentence SummaryHuman genetic variation can modulate the strength of vaccine-induced broadly neutralizing antibody precursor B cell responses.

Published
2023
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26. Human Papillomavirus Virus (HPV) Genotype- and Age-Specific Analyses of External Genital Lesions Among Men in the HPV Infection in Men (HIM) Study

Author

Ingles, Donna J., Campbell, Christine M. Pierce, Messina, Jane A., Stoler, Mark H., Lin, Hui-Yi, Fulp, William J., Abrahamsen, Martha, Sirak, Bradley A., O'Keefe, Michael T., Papenfuss, Mary, Gage, Christine, da Silva, Roberto Carvalho, Sosa, Rossana Gonzalez, Juarez, Oscar Rojas, Villa, Luisa L., Ponce, Eduardo Lazcano, and Giuliano, Anna R.

Published
2015

27. Vaccination induces HIV broadly neutralizing antibody precursors in humans

Author

Leggat, David J., primary, Cohen, Kristen W., additional, Willis, Jordan R., additional, Fulp, William J., additional, deCamp, Allan C., additional, Kalyuzhniy, Oleksandr, additional, Cottrell, Christopher A., additional, Menis, Sergey, additional, Finak, Greg, additional, Ballweber-Fleming, Lamar, additional, Srikanth, Abhinaya, additional, Plyler, Jason R., additional, Schiffner, Torben, additional, Liguori, Alessia, additional, Rahaman, Farhad, additional, Lombardo, Angela, additional, Philiponis, Vincent, additional, Whaley, Rachael E., additional, Seese, Aaron, additional, Brand, Joshua, additional, Ruppel, Alexis M., additional, Hoyland, Wesley, additional, Yates, Nicole L., additional, Williams, LaTonya D., additional, Greene, Kelli, additional, Gao, Hongmei, additional, Mahoney, Celia R., additional, Corcoran, Martin M., additional, Cagigi, Alberto, additional, Taylor, Alison, additional, Brown, David M., additional, Ambrozak, David R., additional, Sincomb, Troy, additional, Hu, Xiaozhen, additional, Tingle, Ryan, additional, Georgeson, Erik, additional, Eskandarzadeh, Saman, additional, Alavi, Nushin, additional, Lu, Danny, additional, Mullen, Tina-Marie, additional, Kubitz, Michael, additional, Groschel, Bettina, additional, Maenza, Janine, additional, Kolokythas, Orpheus, additional, Khati, Nadia, additional, Bethony, Jeffrey, additional, Crotty, Shane, additional, Roederer, Mario, additional, Karlsson Hedestam, Gunilla B., additional, Tomaras, Georgia D., additional, Montefiori, David, additional, Diemert, David, additional, Koup, Richard A., additional, Laufer, Dagna S., additional, McElrath, M. Juliana, additional, McDermott, Adrian B., additional, and Schief, William R., additional

Published
2022
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28. Florida Initiative for Quality Cancer Care: Improvements in Breast Cancer Quality Indicators During a 3-Year Interval

Author

Laronga, Christine, Gray, Jhanelle E., Siegel, Erin M., Lee, Ji-Hyun, Fulp, William J., Fletcher, Michelle, Schreiber, Fred, Brown, Richard, Levine, Richard, Cartwright, Thomas, Abesada-Terk, Guillermo, Jr., Kim, George, Alemany, Carlos, Faig, Douglas, Sharp, Phillip, Markham, Merry-Jennifer, Shibata, David, Malafa, Mokenge, and Jacobsen, Paul B.

Published
2014
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31. 'Secure' Log-Linear and Logistic Regression Analysis of Distributed Databases

Author

Fienberg, Stephen E., Fulp, William J., Slavkovic, Aleksandra B., Wrobel, Tracey A., Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Domingo-Ferrer, Josep, editor, and Franconi, Luisa, editor

Published
2006
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33. Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study

Author

Perdiguero, Beatriz, primary, Asbach, Benedikt, additional, Gómez, Carmen E., additional, Köstler, Josef, additional, Barnett, Susan W., additional, Koutsoukos, Marguerite, additional, Weiss, Deborah E., additional, Cristillo, Anthony D., additional, Foulds, Kathryn E., additional, Roederer, Mario, additional, Montefiori, David C., additional, Yates, Nicole L., additional, Ferrari, Guido, additional, Shen, Xiaoying, additional, Sawant, Sheetal, additional, Tomaras, Georgia D., additional, Sato, Alicia, additional, Fulp, William J., additional, Gottardo, Raphael, additional, Ding, Song, additional, Heeney, Jonathan L., additional, Pantaleo, Giuseppe, additional, Esteban, Mariano, additional, and Wagner, Ralf, additional

Published
2022
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35. TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

Author

Caceres, Gisela, McGraw, Kathy, Yip, Bon Ham, Pellagatti, Andrea, Johnson, Joseph, Zhang, Ling, Liu, Kenian, Zhang, Lan Min, Fulp, William J., Lee, Ji-Hyun, Al Ali, Najla H., Basiorka, Ashley, Smith, Larry J., Daugherty, F. Joseph, Littleton, Neil, Wells, Richard A., Sokol, Lubomir, Wei, Sheng, Komrokji, Rami S., Boultwood, Jacqueline, and List, Alan F.

Published
2013

44. Genomic identification of sarcoma radiosensitivity and the clinical implications for radiation dose personalization

Author

Yang, George, primary, Yuan, Zhigang, additional, Ahmed, Kamran, additional, Welsh, Eric A., additional, Fulp, William J., additional, Gonzalez, Ricardo J., additional, Mullinax, John E., additional, Letson, Douglas, additional, Bui, Marilyn, additional, Harrison, Louis B., additional, Scott, Jacob G., additional, Torres-Roca, Javier F., additional, and Naghavi, Arash O., additional

Published
2021
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46. Lung tumor NF-κB signaling promotes T cell--mediated immune surveillance

Author

Hopewell, Emily L., Zhao, Weipeng, Fulp, William J., Bronk, Crystina C., Lopez, Alexis S., Massengill, Michael, Antonia, Scott, Celis, Esteban, Haura, Eric B., Enkemann, Steven A., Chen, Dung-Tsa, and Beg, Amer A.

Subjects
T cells -- Genetic aspects -- Research, Tumors -- Development and progression -- Genetic aspects -- Research, Cellular signal transduction -- Physiological aspects -- Genetic aspects -- Research, Transcription factors -- Physiological aspects -- Research, Health care industry
Abstract

NF-κB is constitutively activated in many cancer types and is a potential key mediator of tumor-associated inflammation, tumor growth, and metastasis. We investigated the role of cancer cell NF-κB activity [...]

Published
2013
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47. Cutaneous Angiosarcoma: A Single-Institution Experience

Author

Perez, Matthew C., Padhya, Tapan A., Messina, Jane L., Jackson, Ryan S., Gonzalez, Ricardo J., Bui, Marilyn M., Letson, G. Douglas, Cruse, C. W., Lavey, Robert S., Cheong, David, Forster, Meghan R., Fulp, William J., Sondak, Vernon K., and Zager, Jonathan S.

Published
2013
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