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2. Oesophageal cell collection device and biomarker testing to identify high-risk Barrett's patients requiring endoscopic investigation

Author

Chien, Siobhan, primary, Glen, Paul, additional, Penman, Ian, additional, Cruickshank, Neil, additional, Bryce, Gavin, additional, Crumley, Andrew, additional, Phull, Perminder, additional, Miller, Michael, additional, Fletcher, Jonathan, additional, Gunjaca, Ivan, additional, Apollos, Jeyakumar, additional, Robertson, Kevin, additional, and Fullarton, Grant, additional

Published
2024
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3. Learning curves and the influence of procedural volume for the treatment of dysplastic Barrett’s esophagus

Author

Novelli, Marco, Banks, Matthew, Sehgal, Vinay, Graham, David, Sweis, Rami, Morris, Danielle, Miah, Haroon, Dunn, Jason M., Smart, Howard L., Bhandari, Pradeep, Smith, Lesley, Willert, Robert, Fullarton, Grant, Morris, John, Di Pietro, Massimiliano, Gordon, Charles, Penman, Ian, Barr, Hugh, Patel, Praful, Boger, Philip, Kapoor, Neil, Hoare, Jonathan, Direkze, Natalie, Ang, Yeng, Veitch, Andrew, Ragunath, Krish, Cheong, Edward, Dhar, Anjan, Nylander, David, Mahon, Brinder, Narayanasamy, Ravi, O’Toole, Dermot, Lipman, Gideon, Markar, Sheraz, Gupta, Abhinav, Haidry, Rehan J., and Lovat, Laurence B.

Published
2020
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6. National adoption of an esophageal cell collection device for Barrett's esophagus surveillance: impact on delay to investigation and pathological findings.

Author

Chien, Siobhan, Glen, Paul, Penman, Ian, Bryce, Gavin, Cruickshank, Neil, Miller, Michael, Crumley, Andrew, Fletcher, Jonathan, Phull, Perminder, Gunjaca, Ivan, Robertson, Kevin, Apollos, Jeyakumar, Fullarton, Grant, and group, the CytoSCOT

Subjects
BARRETT'S esophagus, TREATMENT delay (Medicine), HEALTH boards
Abstract

High quality Barrett's esophagus surveillance is crucial to detect early neoplastic changes. An esophageal cell collection device (OCCD) was introduced as a triage tool for Barrett's surveillance. This study aims to evaluate whether the Scottish OCCD program (CytoSCOT) has reduced delays to Barrett's surveillance, and whether delayed surveillance negatively impacts endoscopic pathology. All patients undergoing OCCD testing for Barrett's surveillance across 11 Scottish health boards between 14/9/2020 and 13/9/2022 were identified. Patients were dichotomised into two groups (Year 1 vs. Year 2), with individual records interrogated to record demographics, recommended surveillance interval, time from last endoscopy to OCCD test, and OCCD result. Patients were deemed high-risk if the OCCD demonstrated atypia and/or p53 positivity. Further analysis was performed on patients who underwent endoscopy within 12 months of OCCD testing. A total of 3223 OCCD tests were included in the analysis (1478 in Year 1; 1745 in Year 2). In Year 1 versus Year 2, there was a longer median delay to surveillance (9 vs. 5 months; P  < 0.001), increased proportion of patients with delayed surveillance (72.6% vs. 57.0%; P  < 0.001), and more high-risk patients (12.0% vs. 5.3%; P  < 0.001). 425/3223 patients (13.2%) were further investigated with upper gastrointestinal endoscopy, 57.9% of which were high-risk. As surveillance delay increased beyond 24 months, high-risk patients were significantly more likely to develop dysplasia or malignancy (P  = 0.004). Delayed Barrett's esophagus surveillance beyond 24 months is associated with increased risk of pre-cancerous pathology. The CytoSCOT program has reduced delays in surveillance, promoting earlier detection of dysplasia and reducing burden on endoscopy services. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Management of paraesophageal hiatus hernia

Author

Gerdes, Stephan, Schoppmann, Sebastian F, Bonavina, Luigi, Boyle, Nicholas, Mueller-Stich, Beat P, Gutschow, Christian A, Gisbertz, Suzanne Sarah, Kockerling, Ferdinand, Lehmann, Thorsten G, Lorenz, Dietmar, Granderath, Frank Alexander, Rosati, Riccardo, Wullstein, Christoph, Lundell, Lars, Cheong, Edward, Nafteux, Philippe, Olmi, Stefano, Monig, Stefan, Biebl, Matthias, Leers, Jessica, Zehetner, Joerg, Kristo, Ivan, Berrisford, Richard George, Skrobic, Ognjan M, Simic, Aleksandar P, Pera, Manuel, Grimminger, Peter Philipp, Gockel, Ines, Zarras, Konstantinos, Nieuwenhuijs, Vincent Bernard, Gossage, James A, Henegouwen, Mark I van Berge, Stein, Hubert J, Markar, Sheraz R, Hueting, Willem Eduard, Targarona, Eduardo M, Johansson, Jan, Macaulay, Graeme D, Wijnhoven, Bas PL, Benedix, Frank, Attwood, Stephen E, Hoelscher, Arnulf Heinrich, Priego, Pablo, Fuchs, Karl-Hermann, Luyer, Misha DP, Griffiths, Ewen A, Sovik, Torgeir Thorson, Theodorou, Dimitrios, Sgromo, Bruno, Salo, Jarmo A, Singhal, Rishi, Thorell, Anders, Zaninotto, Giovanni, Itenc, Marko, D'journo, Xavier Benoit, Fullarton, Grant M, Horbach, Thomas, Surgery, CCA - Cancer Treatment and Quality of Life, CCA - Cancer biology and immunology, CCA - Imaging and biomarkers, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, and CCA - Cancer Treatment and quality of life

Subjects
REPAIR, MESH, Hiatus hernia, Mesh, Science & Technology, Fundoplication, Surgical technique, GUIDELINES, Paraesophageal hernia, REFLUX, Surgery, Delphi survey, RECURRENCE, Life Sciences & Biomedicine
Abstract

Aims There is considerable controversy regarding optimal management of patients with paraesophageal hiatus hernia (pHH). This survey aims at identifying recommended strategies for work-up, surgical therapy, and postoperative follow-up using Delphi methodology. Methods We conducted a 2-round, 33-question, web-based Delphi survey on perioperative management (preoperative work-up, surgical procedure and follow-up) of non-revisional, elective pHH among European surgeons with expertise in upper-GI. Responses were graded on a 5-point Likert scale and analyzed using descriptive statistics. Items from the questionnaire were defined as “recommended” or “discouraged” if positive or negative concordance among participants was > 75%. Items with lower concordance levels were labelled “acceptable” (neither recommended nor discouraged). Results Seventy-two surgeons with a median (IQR) experience of 23 (14–30) years from 17 European countries participated (response rate 60%). The annual median (IQR) individual and institutional caseload was 25 (15–36) and 40 (28–60) pHH-surgeries, respectively. After Delphi round 2, “recommended” strategies were defined for preoperative work-up (endoscopy), indication for surgery (typical symptoms and/or chronic anemia), surgical dissection (hernia sac dissection and resection, preservation of the vagal nerves, crural fascia and pleura, resection of retrocardial lipoma) and reconstruction (posterior crurorrhaphy with single stitches, lower esophageal sphincter augmentation (Nissen or Toupet), and postoperative follow-up (contrast radiography). In addition, we identified “discouraged” strategies for preoperative work-up (endosonography), and surgical reconstruction (crurorrhaphy with running sutures, tension-free hiatus repair with mesh only). In contrast, many items from the questionnaire including most details of mesh augmentation (indication, material, shape, placement, and fixation technique) were “acceptable”. Conclusions This multinational European Delphi survey represents the first expert-led process to identify recommended strategies for the management of pHH. Our work may be useful in clinical practice to guide the diagnostic process, increase procedural consistency and standardization, and to foster collaborative research.

Published
2023
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8. Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial

Author

Ragunath, Krish, Rameh, Bashir, Fullarton, Grant, Tucker, Art, Penman, Ian, Rodgers, Colin, Neale, James, Edwards, Cathryn, Wise, Adelyn, Jones, Stephen, Church, Nicholas, Vaidya, Kishor, Balata, Sherzad, Todd, John, Gibbons, Michael, Johnston, David, Anderson, Mark, Davies, Gareth, Dickey, William, Murdock, Andrew, Turner, Graham, Goddard, Andrew, Gore, Stephen, Haigh, Chris, Harding, Timothy, Jackson, Lucina, Murray, Iain, Worthingon, Joy, Lee, Thomas, Lim, Peik Loon, McLoughlin, James, Macdonald, Christopher, Mairs, Philip, Monk, David, Preston, Sean, Pugh, Stirling, Smart, Howard, Soliman, Ashraf, Isaacs, Peter, Aldulaimi, David, Trudgill, Nigel, Teare, Julian, Benhamida, Abduljalil, Bell, Andrew, Boulton-Jones, Robert, Daneshmend, Tawfique, Suzuki, Hisaharu, Cullen, Sue, Fitzgerald, Rebecca, Ransford, Rupert, Rahman, Mohammad Mesbahur, Tebala, Giovanni Domenico, Hallissey, Michael, Kelly, Carrie, Hickish, Tamas, Taha, Ali, Rademaker, Johan, Whitehead, Mark, Kelly, Sean, Phull, Perminder, Sharma, Naveen, Perry, Ian, Sankara-Raman, Vankatraman, Ali, Haythem, Khan, Iqbal, Curtis, Howard, Wadley, Martin, Stone, Adam, Sukumaran, Sumesh, Higham, Andrew, Lewis, Stephen, Haycock, Adam, Usselmann, Bernhard, Johnston, Simon Douglas, Tham, Tony, Campbell, Stewart, Douds, Andrew, Dunn, Jason, Sargeant, Ian, Narain, Mark, Maynard, Nick, Chilton, Andrew, Green, Susi, Loft, Duncan, Decadt, Bart, Mendall, Michael, Heydtmann, Mathis, Fisher, Neil, Jankowski, Janusz A Z, de Caestecker, John, Love, Sharon B, Reilly, Gavin, Watson, Peter, Sanders, Scott, Ang, Yeng, Morris, Danielle, Bhandari, Pradeep, Brooks, Claire, Attwood, Stephen, Harrison, Rebecca, Barr, Hugh, and Moayyedi, Paul

Published
2018
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9. Radiofrequency Ablation and Endoscopic Mucosal Resection for Dysplastic Barrett's Esophagus and Early Esophageal Adenocarcinoma: Outcomes of the UK National Halo RFA Registry

Author

Haidry, Rehan J., Dunn, Jason M., Butt, Mohammed A., Burnell, Matthew G., Gupta, Abhinav, Green, Sarah, Miah, Haroon, Smart, Howard L., Bhandari, Pradeep, Smith, Lesley Ann, Willert, Robert, Fullarton, Grant, Morris, John, Di Pietro, Massimo, Gordon, Charles, Penman, Ian, Barr, Hugh, Patel, Praful, Boger, Philip, Kapoor, Neel, Mahon, Brinder, Hoare, Jonathon, Narayanasamy, Ravi, O'Toole, Dermot, Cheong, Edward, Direkze, Natalie C., Ang, Yeng, Novelli, Marco, Banks, Matthew R., and Lovat, Laurence Bruce

Published
2013
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11. Consensus Statements for Management of Barrett's Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process

Author

Bennett, Cathy, Vakil, Nimish, Bergman, Jacques, Harrison, Rebecca, Odze, Robert, Vieth, Michael, Sanders, Scott, Gay, Laura, Pech, Oliver, Longcroft–Wheaton, Gaius, Romero, Yvonne, Inadomi, John, Tack, Jan, Corley, Douglas A., Manner, Hendrik, Green, Susi, Al Dulaimi, David, Ali, Haythem, Allum, Bill, Anderson, Mark, Curtis, Howard, Falk, Gary, Fennerty, M. Brian, Fullarton, Grant, Krishnadath, Kausilia, Meltzer, Stephen J., Armstrong, David, Ganz, Robert, Cengia, Gianpaolo, Going, James J., Goldblum, John, Gordon, Charles, Grabsch, Heike, Haigh, Chris, Hongo, Michio, Johnston, David, Forbes–Young, Ricky, Kay, Elaine, Kaye, Philip, Lerut, Toni, Lovat, Laurence B., Lundell, Lars, Mairs, Philip, Shimoda, Tadakuza, Spechler, Stuart, Sontag, Stephen, Malfertheiner, Peter, Murray, Iain, Nanji, Manoj, Poller, David, Ragunath, Krish, Regula, Jaroslaw, Cestari, Renzo, Shepherd, Neil, Singh, Rajvinder, Stein, Hubert J., Talley, Nicholas J., Galmiche, Jean–Paul, Tham, Tony C.K., Watson, Peter, Yerian, Lisa, Rugge, Massimo, Rice, Thomas W., Hart, John, Gittens, Stuart, Hewin, David, Hochberger, Juergen, Kahrilas, Peter, Preston, Sean, Sampliner, Richard, Sharma, Prateek, Stuart, Robert, Wang, Kenneth, Waxman, Irving, Abley, Chris, Loft, Duncan, Penman, Ian, Shaheen, Nicholas J., Chak, Amitabh, Davies, Gareth, Dunn, Lorna, Falck–Ytter, Yngve, Decaestecker, John, Bhandari, Pradeep, Ell, Christian, Griffin, S. Michael, Attwood, Stephen, Barr, Hugh, Allen, John, Ferguson, Mark K., Moayyedi, Paul, and Jankowski, Janusz A.Z.

Published
2012
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16. Radiofrequency Ablation vs Endoscopic Surveillance for Patients With Barrett Esophagus and Low-Grade Dysplasia: A Randomized Clinical Trial

Author

Phoa, Nadine K., van Vilsteren, Frederike G. I., Weusten, Bas L. A. M., Bisschops, Raf, Schoon, Erik J., Ragunath, Krish, Fullarton, Grant, Di Pietro, Massimiliano, Ravi, Narayanasamy, Visser, Mike, Offerhaus, Johan G., Seldenrijk, Cees A., Meijer, Sybren L., ten Kate, Fiebo J. W., Tijssen, Jan G. P., and Bergman, Jacques J. G. H. M.

Published
2014
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22. Learning curves and the influence of procedural volume for the treatment of dysplastic Barrett’s esophagus

Author

Lipman, Gideon, primary, Markar, Sheraz, additional, Gupta, Abhinav, additional, Haidry, Rehan J., additional, Lovat, Laurence B., additional, Novelli, Marco, additional, Banks, Matthew, additional, Sehgal, Vinay, additional, Graham, David, additional, Sweis, Rami, additional, Morris, Danielle, additional, Miah, Haroon, additional, Dunn, Jason M., additional, Smart, Howard L., additional, Bhandari, Pradeep, additional, Smith, Lesley, additional, Willert, Robert, additional, Fullarton, Grant, additional, Morris, John, additional, Di Pietro, Massimiliano, additional, Gordon, Charles, additional, Penman, Ian, additional, Barr, Hugh, additional, Patel, Praful, additional, Boger, Philip, additional, Kapoor, Neil, additional, Hoare, Jonathan, additional, Direkze, Natalie, additional, Ang, Yeng, additional, Veitch, Andrew, additional, Ragunath, Krish, additional, Cheong, Edward, additional, Dhar, Anjan, additional, Nylander, David, additional, Mahon, Brinder, additional, Narayanasamy, Ravi, additional, and O’Toole, Dermot, additional

Published
2020
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29. Esomeprazole and aspirin in Barrett's oesophagus (AspECT): a randomised factorial trial

Author

Jankowski, Janusz A Z, primary, de Caestecker, John, additional, Love, Sharon B, additional, Reilly, Gavin, additional, Watson, Peter, additional, Sanders, Scott, additional, Ang, Yeng, additional, Morris, Danielle, additional, Bhandari, Pradeep, additional, Brooks, Claire, additional, Attwood, Stephen, additional, Harrison, Rebecca, additional, Barr, Hugh, additional, Moayyedi, Paul, additional, Ragunath, Krish, additional, Rameh, Bashir, additional, Fullarton, Grant, additional, Tucker, Art, additional, Penman, Ian, additional, Rodgers, Colin, additional, Neale, James, additional, Edwards, Cathryn, additional, Wise, Adelyn, additional, Jones, Stephen, additional, Church, Nicholas, additional, Vaidya, Kishor, additional, Balata, Sherzad, additional, Todd, John, additional, Gibbons, Michael, additional, Johnston, David, additional, Anderson, Mark, additional, Davies, Gareth, additional, Dickey, William, additional, Murdock, Andrew, additional, Turner, Graham, additional, Goddard, Andrew, additional, Gore, Stephen, additional, Haigh, Chris, additional, Harding, Timothy, additional, Jackson, Lucina, additional, Murray, Iain, additional, Worthingon, Joy, additional, Lee, Thomas, additional, Lim, Peik Loon, additional, McLoughlin, James, additional, Macdonald, Christopher, additional, Mairs, Philip, additional, Monk, David, additional, Preston, Sean, additional, Pugh, Stirling, additional, Smart, Howard, additional, Soliman, Ashraf, additional, Isaacs, Peter, additional, Aldulaimi, David, additional, Trudgill, Nigel, additional, Teare, Julian, additional, Benhamida, Abduljalil, additional, Bell, Andrew, additional, Boulton-Jones, Robert, additional, Daneshmend, Tawfique, additional, Suzuki, Hisaharu, additional, Cullen, Sue, additional, Fitzgerald, Rebecca, additional, Ransford, Rupert, additional, Rahman, Mohammad Mesbahur, additional, Tebala, Giovanni Domenico, additional, Hallissey, Michael, additional, Kelly, Carrie, additional, Hickish, Tamas, additional, Taha, Ali, additional, Rademaker, Johan, additional, Whitehead, Mark, additional, Kelly, Sean, additional, Phull, Perminder, additional, Sharma, Naveen, additional, Perry, Ian, additional, Sankara-Raman, Vankatraman, additional, Ali, Haythem, additional, Khan, Iqbal, additional, Curtis, Howard, additional, Wadley, Martin, additional, Stone, Adam, additional, Sukumaran, Sumesh, additional, Higham, Andrew, additional, Lewis, Stephen, additional, Haycock, Adam, additional, Usselmann, Bernhard, additional, Johnston, Simon Douglas, additional, Tham, Tony, additional, Campbell, Stewart, additional, Douds, Andrew, additional, Dunn, Jason, additional, Sargeant, Ian, additional, Narain, Mark, additional, Maynard, Nick, additional, Chilton, Andrew, additional, Green, Susi, additional, Loft, Duncan, additional, Decadt, Bart, additional, Mendall, Michael, additional, Heydtmann, Mathis, additional, and Fisher, Neil, additional

Published
2018
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30. 481 LONG-TERM FOLLOW-UP RESULTS OF A RANDOMIZED TRIAL COMPARING RADIOFREQUENCY ABLATION VERSUS ENDOSCOPIC SURVEILLANCE IN BARRETT'S ESOPHAGUS PATIENTS WITH LOW-GRADE DYSPLASIA

Author

Klaver, Esther, primary, Phoa, K. Nadine, additional, van Vilsteren, Frederike G., additional, Weusten, Bas L., additional, Bisschops, Raf, additional, Schoon, Erik. J., additional, Pech, Oliver, additional, Manner, Hendrik, additional, Ragunath, Krish, additional, Fernández-Sordo, Jacobo Ortiz, additional, Fullarton, Grant, additional, Di Pietro, Massimiliano, additional, Januszewicz, Wladyslaw, additional, Narayanasamy, Ravi, additional, O'Toole, Dermot, additional, Bergman, Jacques, additional, and Pouw, Roos E., additional

Published
2018
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32. 841 Residual Intestinal Metaplasia After Successful Endoscopic Therapy for Barrett's Related Neoplasia Confers Higher Long Term Risk for Disease Recurrence, on Behalf of the UK RFA Registry

Author

Lipman, Gideon, primary, Gupta, Abhinav, additional, Banks, Matthew, additional, Sweis, Rami, additional, Dunn, Jason M., additional, Miah, Haroon, additional, Morris, Danielle, additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Willert, Robert P., additional, Fullarton, Grant, additional, Morris, Allan J., additional, Pietro, Massimiliano Di, additional, Mundre, Pradeep, additional, Gordon, Charles, additional, Penman, Ian, additional, Barr, Hugh, additional, Patel, Praful, additional, Boger, Philip, additional, Kapoor, Neil, additional, Mahon, Brinder S., additional, Hoare, Jonathan, additional, Narayanasamy, Ravi, additional, O'Toole, Dermot, additional, Direkze, Natalie, additional, Ang, Yeng, additional, Veitch, Andrew, additional, Nylander, David, additional, Dhar, Anjan, additional, Ragunath, Krish, additional, Leahy, Anthony, additional, Fullard, Mark, additional, Haidry, Rehan, additional, and Lovat, Laurence, additional

Published
2016
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33. Reply to Kristo et al.

Author

Haidry, Rehan, additional, Lipman, Gideon, additional, Banks, Matthew, additional, Butt, Mohammed, additional, Sehgal, Vinay, additional, Graham, David, additional, Dunn, Jason, additional, Gupta, Abhinav, additional, Sweis, Rami, additional, Miah, Haroon, additional, Morris, Danielle, additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Willert, Robert, additional, Fullarton, Grant, additional, Morris, Jonathon, additional, Di Pietro, Massimo, additional, Gordon, Charles, additional, Penman, Ian, additional, Barr, High, additional, Patel, Praful, additional, Boger, Philip, additional, Kapoor, Neil, additional, Mahon, Brinder, additional, Hoare, Jonathon, additional, Narayanasamy, Ravi, additional, O’Toole, Dermot, additional, Cheong, Edward, additional, Direkze, Natalie, additional, Ang, Yeng, additional, Veitch, Andrew, additional, Dhar, Anjan, additional, Nyalender, David, additional, Ragunath, Krish, additional, Leahy, Anthony, additional, Fullard, Mark, additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2015
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34. Comparing outcome of radiofrequency ablation in Barrett’s with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry

Author

Haidry, Rehan, additional, Lipman, Gideon, additional, Banks, Matthew, additional, Butt, Mohammed, additional, Sehgal, Vinay, additional, Graham, David, additional, Dunn, Jason, additional, Gupta, Abhinav, additional, Sweis, Rami, additional, Miah, Haroon, additional, Morris, Danielle, additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Willert, Robert, additional, Fullarton, Grant, additional, Morris, Jonathon, additional, Di Pietro, Massimo, additional, Gordon, Charles, additional, Penman, Ian, additional, Barr, High, additional, Patel, Praful, additional, Boger, Philip, additional, Kapoor, Neil, additional, Mahon, Brinder, additional, Hoare, Jonathon, additional, Narayanasamy, Ravi, additional, O’Toole, Dermot, additional, Cheong, Edward, additional, Direkze, Natalie, additional, Ang, Yeng, additional, Veitch, Andrew, additional, Dhar, Anjan, additional, Nyalender, David, additional, Ragunath, Krish, additional, Leahy, Anthony, additional, Fullard, Mark, additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2015
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36. Sa1081 Outcomes of Patients Who Fail Initial Endoscopic Therapy for Barrett's Related Neoplasia

Author

Haidry, Rehan J., primary, Lipman, Gideon, additional, Butt, Mohammed A., additional, Gupta, Abhinav, additional, Sweis, Rami, additional, Dunn, Jason M., additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Willert, Robert P., additional, Fullarton, Grant, additional, Morris, Jonathon, additional, di Pietro, Massimiliano, additional, Gordon, Charles, additional, Penman, Ian D., additional, Barr, Hugh, additional, Boger, Philip C., additional, Kapoor, Neil, additional, Mahon, Brinder S., additional, Hoare, Jonathan M., additional, Ravi, Narayanasamy, additional, O'Toole, Dermot, additional, Ang, Yeng, additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, Banks, Matthew R., additional, and Lovat, Laurence, additional

Published
2015
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37. 53 Six Year Disease Durability Outcomes on Patients Treated With Endoscopic Therapy for Barrett's Related Neoplasia From the UK Registry

Author

Haidry, Rehan J., primary, Lipman, Gideon, additional, Butt, Mohammed A., additional, Gupta, Abhinav, additional, Sweis, Rami, additional, Dunn, Jason M., additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Willert, Robert P., additional, Fullarton, Grant, additional, Morris, Jonathon, additional, di Pietro, Massimiliano, additional, Gordon, Charles, additional, Penman, Ian D., additional, Barr, Hugh, additional, Boger, Philip C., additional, Kapoor, Neil, additional, Mahon, Brinder S., additional, Hoare, Jonathan M., additional, Ravi, Narayanasamy, additional, O'Toole, Dermot, additional, Ang, Yeng, additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, Banks, Matthew R., additional, and Lovat, Laurence, additional

Published
2015
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39. Tu1340 Recurrence After Successful Radiofrequency Ablation for Barrett's Related Neoplasia Is More Likely in Males: Data From the United Kingdom Patient Registry

Author

Haidry, Rehan J., primary, Banks, Matthew R., additional, Gupta, Abhinav, additional, Butt, Mohammed a., additional, Fullarton, Grant, additional, Smart, Howard, additional, Morris, Allan J., additional, Willert, Robert P., additional, Ravi, Narayanasamy, additional, Rodriguez-Justo, Manuel, additional, Di Pietro, Massimiliano, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2014
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40. Tu1333 Long Term Follow up After Successful Radiofrequency Ablation for Barrett's Related Neoplasia Is Essential to Diagnose Recurrent Disease: Data From the United Kingdom Patient Registry

Author

Haidry, Rehan J., primary, Banks, Matthew R., additional, Butt, Mohammed a., additional, Gupta, Abhinav, additional, Fullarton, Grant, additional, Morris, Allan J., additional, Di Pietro, Massimiliano, additional, Willert, Robert P., additional, Ravi, Narayanasamy, additional, Smart, Howard, additional, Penman, Ian D., additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2014
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41. Mo1108 Cost-Effectiveness Analysis of Radiofrequency Ablation for Barrett's Esophagus With Low-Grade Dysplasia: Results From a Randomized Controlled Trial (SURF)

Author

Phoa, Kai Yi N., primary, Rosmolen, Wilda, additional, Weusten, Bas L., additional, Bisschops, Raf, additional, Schoon, Erik J., additional, Ragunath, Krish, additional, Fullarton, Grant, additional, Pietro, Massimiliano di, additional, Ravi, Narayanasamy, additional, Visser, Mike, additional, Offerhaus, Johan, additional, Seldenrijk, Cees A., additional, Meijer, Sybren L., additional, Ten Kate, Fiebo T., additional, Tijssen, Jan, additional, Dijkgraaf, Marcel G., additional, and Bergman, Jacques J., additional

Published
2014
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42. Tu1334 Treatment Outcomes for Barrett's Esophagus Related Neoplasia Have Improved Over Time With Changes in Endoscopic Practice: Five Year Experience From the First Five Hundred Patients in the United Kingdom Registry

Author

Haidry, Rehan J., primary, Banks, Matthew R., additional, Gupta, Abhinav, additional, Butt, Mohammed a., additional, Fullarton, Grant, additional, Morris, Allan J., additional, Penman, Ian D., additional, Di Pietro, Massimiliano, additional, Smart, Howard, additional, Willert, Robert P., additional, Rodriguez-Justo, Manuel, additional, Ravi, Narayanasamy, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2014
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43. 353 Patients Treated With Radiofrequency Ablation for Intramucosal Carcinoma Arising in Barrett's Eosophagus Have Similar Outcomes to Those With High Grade Dysplasia: Data From the United Kingdom Registry

Author

Haidry, Rehan J., primary, Banks, Matthew R., additional, Gupta, Abhinav, additional, Butt, Mohammed a., additional, Fullarton, Grant, additional, Morris, Allan J., additional, Penman, Ian D., additional, Di Pietro, Massimiliano, additional, Willert, Robert P., additional, Rodriguez-Justo, Manuel, additional, Novelli, Marco, additional, Ravi, Narayanasamy, additional, Smart, Howard, additional, and Lovat, Laurence, additional

Published
2014
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44. Increased prevalence of precancerous changes in relatives of gastric cancer patients: critical role of H. pylori

Author

El–Omar, Emad M., Oien, Karin, Murray, Lilian S., El–Nujumi, Adil, Wirz, Angela, Gillen, Derek, Williams, Craig, Fullarton, Grant, and McColl, Kenneth E.L.

Subjects
digestive, oral, and skin physiology, digestive system diseases
Abstract

Background & Aims:Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of patients with gastric cancer have an increased risk of developing gastric cancer. The aim of this study was to determine the prevalence of atrophy and hypochlorhydria and their association with H. pylori infection in first-degree relatives of patients with gastric cancer. Methods:H. pylori status, gastric secretory function, and gastric histology were studied in 100 first-degree relatives of patients with noncardia gastric cancer and compared with those of controls with no family history of this cancer. Results: Compared with healthy controls, relatives of patients with gastric cancer had a higher prevalence of hypochlorhydria (27% vs. 3%) but a similar prevalence of H. pylori infection (63% vs. 64%). Relatives of cancer patients also had a higher prevalence of atrophy (34%) than patients with nonulcer dyspepsia (5%) matched for H. pylori prevalence. Among the relatives of cancer patients, the prevalence of atrophy and hypochlorhydria was increased only in those with evidence of H. pylori infection, was greater in relatives of patients with familial cancer than in relatives of sporadic cancer index patients, and increased with age. Eradication of H. pylori infection produced resolution of the gastric inflammation in each subject and resolution of hypochlorhydria and atrophy in 50% of the subjects. Conclusions: Relatives of patients with gastric cancer have an increased prevalence of precancerous gastric abnormalities, but this increase is confined to those with H. pylori infection. Consequently, prophylactic eradication of the infection should be offered to such subjects.

Published
2000

45. Su1500 Radiofrequency Ablation (RRA) Confers Sustained Benefit for Squamous High Grade Dysplasia (HGD) and Early Squamous Cell Carcinoma (SCC) in Patients WHO Do Not Progress Following the First Treatment

Author

Haidry, Rehan J., primary, Banks, Matthew R., additional, Butt, Mohammed A., additional, Gupta, Abhinav, additional, Louis-Auguste, John R., additional, Dunn, Jason M., additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Smith, Lesley Ann, additional, Willert, Robert P., additional, Fullarton, Grant, additional, Di Pietro, Massimiliano, additional, Penman, Ian D., additional, Narayanasamy, Ravi, additional, Gordon, Charles, additional, O'Toole, Dermot, additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2013
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46. 283 Patients Undergoing Radiofrequency Ablation (RFA) for Barrett's Related Neoplasia Have Improved Outcomes With Decreasing Length's of Baseline Barrett's Eosophagus (BE) and Increasing Number of RFA Sessions

Author

Haidry, Rehan J., primary, Butt, Mohammed a., additional, Gupta, Abhinav, additional, Louis-Auguste, John R., additional, Dunn, Jason M., additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Smith, Lesley Ann, additional, Willert, Robert P., additional, Fullarton, Grant, additional, Di Pietro, Massimiliano, additional, Gordon, Charles, additional, Penman, Ian D., additional, Barr, Hugh, additional, Patel, Praful, additional, Boger, Philip C., additional, Kapoor, Neil, additional, Mahon, Brinder S., additional, Hoare, Jonathan M., additional, Burnell, Matthew, additional, Narayanasamy, Ravi, additional, O'Toole, Dermot, additional, Cheong, Edward, additional, Direkze, Natalie, additional, Ang, Yeng S., additional, Novelli, Marco, additional, Banks, Matthew R., additional, and Lovat, Laurence, additional

Published
2013
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47. 1004 Radiofrequency Ablation in Barrett's Esophagus With Confirmed Low-Grade Dysplasia: Interim Results of a European Multicenter Randomized Controlled Trial (SURF)

Author

Phoa, Kai Yi N., primary, van Vilsteren, Frederike G., additional, Pouw, Roos E., additional, Weusten, Bas L., additional, Schoon, Erik J., additional, Bisschops, Raf, additional, Ragunath, Krish, additional, Fullarton, Grant, additional, di Pietro, Massimiliano, additional, Fitzgerald, Rebecca, additional, O'Toole, Dermot, additional, Narayanasamy, Ravi, additional, Pech, Oliver, additional, Tanck, Michael, additional, Visser, Mike, additional, Offerhaus, Johan, additional, Seldenrijk, Cees A., additional, Meijer, Sybren L., additional, ten Kate, Fiebo J., additional, and Bergman, Jacques J., additional

Published
2013
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48. Su1110 HALO Radiofrequency Ablation for Squamous High Grade Dysplasia and Early Squamous Cell Carcinoma: Outcomes Form the UK HALO Radiofrequency Ablation Registry

Author

Haidry, Rehan J., primary, Dunn, Jason M., additional, Banks, Matthew R., additional, Gupta, Abhinav, additional, Butt, Mohammed A., additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Smith, Lesley Ann, additional, Willert, Robert P., additional, Fullarton, Grant, additional, di Pietro, Massimiliano, additional, Penman, Ian D., additional, Novelli, Marco, additional, and Lovat, Laurence, additional

Published
2012
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49. Tu1097 HALO Radiofrequency Ablation for High Grade Dysplasia and Early Mucosal Neoplasia Arising in Barrett's Oesophagus: Interim Results Form the UK HALO Radiofrequency Ablation Registry

Author

Haidry, Rehan J., primary, Dunn, Jason M., additional, Banks, Matthew R., additional, Butt, Mohammed A., additional, Gupta, Abhinav, additional, Fullarton, Grant, additional, Smart, Howard, additional, Penman, Ian D., additional, di Pietro, Massimiliano, additional, Willert, Robert P., additional, Barr, Hugh, additional, Bhandari, Pradeep, additional, Gordon, Charles, additional, Patel, Praful, additional, Boger, Philip C., additional, Kapoor, Neil, additional, Smith, Lesley Ann, additional, Mahon, Brinder S., additional, Novelli, Marco, additional, Burnell, Matthew, additional, and Lovat, Laurence, additional

Published
2012
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50. Radio Frequency Ablation is More Effective in Shorter Segments of Barrett's Oesophagus for Eradication of High Grade Dysplasia/ Intramucosal Cancer – Results From the UK RFA HALO Registry

Author

Haidry, Rehan J., primary, Dunn, Jason M., additional, Thorpe, Sally, additional, Fullarton, Grant, additional, Smart, Howard, additional, Bhandari, Pradeep, additional, Kapoor, Neil, additional, Patel, Praful, additional, Willert, Robert P., additional, Penman, Ian D., additional, Banks, Matthew R., additional, and Lovat, Laurence B., additional

Published
2011
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