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2. Clinical presentation of calmodulin mutations: the International Calmodulinopathy Registry

Author

Crotti, L, Spazzolini, C, Nyegaard, M, Overgaard, M, Kotta, M, Dagradi, F, Sala, L, Aiba, T, Ayers, M, Baban, A, Barc, J, Beach, C, Behr, E, Bos, J, Cerrone, M, Covi, P, Cuneo, B, Denjoy, I, Donner, B, Elbert, A, Eliasson, H, Etheridge, S, Fukuyama, M, Girolami, F, Hamilton, R, Horie, M, Iascone, M, Jaimez, J, Jensen, H, Kannankeril, P, Kaski, J, Makita, N, Muñoz-Esparza, C, Odland, H, Ohno, S, Papagiannis, J, Porretta, A, Prandstetter, C, Probst, V, Robyns, T, Rosenthal, E, Rosés-Noguer, F, Sekarski, N, Singh, A, Spentzou, G, Stute, F, Tfelt-Hansen, J, Till, J, Tobert, K, Vinocur, J, Webster, G, Wilde, A, Wolf, C, Ackerman, M, Schwartz, P, Crotti L., Spazzolini C., Nyegaard M., Overgaard M. T., Kotta M. C., Dagradi F., Sala L., Aiba T., Ayers M. D., Baban A., Barc J., Beach C. M., Behr E. R., Bos J. M., Cerrone M., Covi P., Cuneo B., Denjoy I., Donner B., Elbert A., Eliasson H., Etheridge S. P., Fukuyama M., Girolami F., Hamilton R., Horie M., Iascone M., Jaimez J. J., Jensen H. K., Kannankeril P. J., Kaski J. P., Makita N., Muñoz-Esparza C., Odland H. H., Ohno S., Papagiannis J., Porretta A. P., Prandstetter C., Probst V., Robyns T., Rosenthal E., Rosés-Noguer F., Sekarski N., Singh A., Spentzou G., Stute F., Tfelt-Hansen J., Till J., Tobert K. E., Vinocur J. M., Webster G., Wilde A. A. M., Wolf C. M., Ackerman M. J., Schwartz P. J., Crotti, L, Spazzolini, C, Nyegaard, M, Overgaard, M, Kotta, M, Dagradi, F, Sala, L, Aiba, T, Ayers, M, Baban, A, Barc, J, Beach, C, Behr, E, Bos, J, Cerrone, M, Covi, P, Cuneo, B, Denjoy, I, Donner, B, Elbert, A, Eliasson, H, Etheridge, S, Fukuyama, M, Girolami, F, Hamilton, R, Horie, M, Iascone, M, Jaimez, J, Jensen, H, Kannankeril, P, Kaski, J, Makita, N, Muñoz-Esparza, C, Odland, H, Ohno, S, Papagiannis, J, Porretta, A, Prandstetter, C, Probst, V, Robyns, T, Rosenthal, E, Rosés-Noguer, F, Sekarski, N, Singh, A, Spentzou, G, Stute, F, Tfelt-Hansen, J, Till, J, Tobert, K, Vinocur, J, Webster, G, Wilde, A, Wolf, C, Ackerman, M, Schwartz, P, Crotti L., Spazzolini C., Nyegaard M., Overgaard M. T., Kotta M. C., Dagradi F., Sala L., Aiba T., Ayers M. D., Baban A., Barc J., Beach C. M., Behr E. R., Bos J. M., Cerrone M., Covi P., Cuneo B., Denjoy I., Donner B., Elbert A., Eliasson H., Etheridge S. P., Fukuyama M., Girolami F., Hamilton R., Horie M., Iascone M., Jaimez J. J., Jensen H. K., Kannankeril P. J., Kaski J. P., Makita N., Muñoz-Esparza C., Odland H. H., Ohno S., Papagiannis J., Porretta A. P., Prandstetter C., Probst V., Robyns T., Rosenthal E., Rosés-Noguer F., Sekarski N., Singh A., Spentzou G., Stute F., Tfelt-Hansen J., Till J., Tobert K. E., Vinocur J. M., Webster G., Wilde A. A. M., Wolf C. M., Ackerman M. J., and Schwartz P. J.

Abstract

Aims: Calmodulinopathy due to mutations in any of the three CALM genes (CALM1-3) causes life-threatening arrhythmia syndromes, especially in young individuals. The International Calmodulinopathy Registry (ICalmR) aims to define and link the increasing complexity of the clinical presentation to the underlying molecular mechanisms. Methods and results: The ICalmR is an international, collaborative, observational study, assembling and analysing clinical and genetic data on CALM-positive patients. The ICalmR has enrolled 140 subjects (median age 10.8 years [interquartile range 5-19]), 97 index cases and 43 family members. CALM-LQTS and CALM-CPVT are the prevalent phenotypes. Primary neurological manifestations, unrelated to post-anoxic sequelae, manifested in 20 patients. Calmodulinopathy remains associated with a high arrhythmic event rate (symptomatic patients, n = 103, 74%). However, compared with the original 2019 cohort, there was a reduced frequency and severity of all cardiac events (61% vs. 85%; P =. 001) and sudden death (9% vs. 27%; P =. 008). Data on therapy do not allow definitive recommendations. Cardiac structural abnormalities, either cardiomyopathy or congenital heart defects, are present in 30% of patients, mainly CALM-LQTS, and lethal cases of heart failure have occurred. The number of familial cases and of families with strikingly different phenotypes is increasing. Conclusion: Calmodulinopathy has pleiotropic presentations, from channelopathy to syndromic forms. Clinical severity ranges from the early onset of life-threatening arrhythmias to the absence of symptoms, and the percentage of milder and familial forms is increasing. There are no hard data to guide therapy, and current management includes pharmacological and surgical antiadrenergic interventions with sodium channel blockers often accompanied by an implantable cardioverter-defibrillator.

Published
2023

5. 28-GHz ECHCD system with beam focusing launcher on the QUEST spherical tokamak

Author

Idei, H., Onchi, T., Kariya, T., Tsujimura, T.I., Kubo, S., Kobayashi, S., Sakaguchi, M., Imai, T., Hasegawa, M., Nakamura, K., Mishra, K., Fukuyama, M., Yunoki, M., Kojima, S., Watanabe, O., Kuroda, K., Hanada, K., Nagashima, Y., Ejiri, A., Matsumoto, N., Ono, M., Higashijima, A., Nagata, T., Shimabukoro, S., Takase, Y., Fukuyama, A., and Murakami, S.

Published
2019
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7. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., Zsuga L., Pedersen, T, Abramovic, I, Agostinetti, P, Torres, M, Akaslompolo, S, Belloso, J, Aleynikov, P, Aleynikova, K, Alhashimi, M, Ali, A, Allen, N, Alonso, A, Anda, G, Andreeva, T, Angioni, C, Arkhipov, A, Arnold, A, Asad, W, Ascasibar, E, Aumeunier, M, Avramidis, K, Aymerich, E, Baek, S, Bahner, J, Baillod, A, Balden, M, Baldzuhn, J, Ballinger, S, Banduch, M, Bannmann, S, Navarro, A, Barbui, T, Beidler, C, Belafdil, C, Bencze, A, Benndorf, A, Beurskens, M, Biedermann, C, Biletskyi, O, Blackwell, B, Blatzheim, M, Bluhm, T, Bockenhoff, D, Bongiovi, G, Borchardt, M, Borodin, D, Boscary, J, Bosch, H, Bosmann, T, Boswirth, B, Bottger, L, Bottino, A, Bozhenkov, S, Brakel, R, Brandt, C, Brauer, T, Braune, H, Brezinsek, S, Brunner, K, Buller, S, Burhenn, R, Bussiahn, R, Buttenschon, B, Buzas, A, Bykov, V, Calvo, I, Mata, K, Caminal, I, Cannas, B, Cappa, A, Carls, A, Carovani, F, Carr, M, Carralero, D, Carvalho, B, Casas, J, Castano-Bardawil, D, Castejon, F, Chaudhary, N, Chelis, I, Chomiczewska, A, Coenen, J, Cole, M, Cordella, F, Corre, Y, Crombe, K, Cseh, G, Csillag, B, Damm, H, Day, C, de Baar, M, De la Cal, E, Degenkolbe, S, Demby, A, Denk, S, Dhard, C, Di Siena, A, Dinklage, A, Dittmar, T, Dreval, M, Drevlak, M, Drewelow, P, Drews, P, Dunai, D, Edlund, E, Effenberg, F, Ehrke, G, Endler, M, Ennis, D, Escoto, F, Estrada, T, Fable, E, Fahrenkamp, N, Fanni, A, Faustin, J, Fellinger, J, Feng, Y, Figacz, W, Flom, E, Ford, O, Fornal, T, Frerichs, H, Freundt, S, Fuchert, G, Fukuyama, M, Fullenbach, F, Gantenbein, G, Gao, Y, Garcia, K, Regana, J, Garcia-Cortes, I, Gaspar, J, Gates, D, Geiger, J, Geiger, B, Giudicotti, L, Gonzalez, A, Goriaev, A, Gradic, D, Grahl, M, Graves, J, Green, J, Grelier, E, Greuner, H, Gross, S, Grote, H, Groth, M, Gruca, M, Grulke, O, Grun, M, Arnaiz, J, Gunter, S, Haak, V, Haas, M, Hacker, P, Hakola, A, Hallenbert, A, Hammond, K, Han, X, Hansen, S, Harris, J, Hartfuss, H, Hartmann, D, Hathiramani, D, Hatzky, R, Hawke, J, Hegedus, S, Hein, B, Heinemann, B, Helander, P, Henneberg, S, Hergenhahn, U, Hidalgo, C, Hindenlang, F, Hirsch, M, Hofel, U, Hollfeld, K, Holtz, A, Hopf, D, Hoschen, D, Houry, M, Howard, J, Huang, X, Hubeny, M, Hudson, S, Ida, K, Igitkhanov, Y, Igochine, V, Illy, S, Ionita-Schrittwieser, C, Isobe, M, Jablczynska, M, Jablonski, S, Jagielski, B, Jakubowski, M, van Vuuren, A, Jelonnek, J, Jenko, F, Jensen, T, Jenzsch, H, Junghanns, P, Kaczmarczyk, J, Kallmeyer, J, Kamionka, U, Kandler, M, Kasilov, S, Kazakov, Y, Kennedy, D, Kharwandikar, A, Khokhlov, M, Kiefer, C, Killer, C, Kirschner, A, Kleiber, R, Klinger, T, Klose, S, Knauer, J, Knieps, A, Kochl, F, Kocsis, G, Kolesnichenko, Y, Konies, A, Konig, R, Kontula, J, Kornejew, P, Koschinsky, J, Kozulia, M, Kramer-Flecken, A, Krampitz, R, Krause, M, Krawczyk, N, Kremeyer, T, Krier, L, Kriete, D, Krychowiak, M, Ksiazek, I, Kubkowska, M, Kuczynski, M, Kuhner, G, Kumar, A, Kurki-Suonio, T, Kwak, S, Landreman, M, Lang, P, Langenberg, A, Laqua, H, Laube, R, Lazerson, S, Lewerentz, M, Li, C, Liang, Y, Linsmeier, C, Lion, J, Litnovsky, A, Liu, S, Lobsien, J, Loizu, J, Lore, J, Lorenz, A, Losada, U, Louche, F, Lunsford, R, Lutsenko, V, Machielsen, M, Mackel, F, Maisano-Brown, J, Maj, O, Makowski, D, Manduchi, G, Maragkoudakis, E, Marchuk, O, Marsen, S, Martines, E, Martinez-Fernandez, J, Marushchenko, M, Masuzaki, S, Maurer, D, Mayer, M, Mccarthy, K, Mccormack, O, Mcneely, P, Meister, H, Mendelevitch, B, Mendes, S, Merlo, A, Messian, A, Mielczarek, A, Mishchenko, O, Missal, B, Mitteau, R, Moiseenko, V, Mollen, A, Moncada, V, Monnich, T, Morisaki, T, Moseev, D, Motojima, G, Mulas, S, Mulsow, M, Nagel, M, Naujoks, D, Naulin, V, Neelis, T, Neilson, H, Neu, R, Neubauer, O, Neuner, U, Nicolai, D, Nielsen, S, Niemann, H, Nishiza, T, Nishizawa, T, Nuhrenberg, C, Ochoukov, R, Oelmann, J, Offermanns, G, Ogawa, K, Okamura, S, Olmanns, J, Ongena, J, Oosterbeek, J, Otte, M, Pablant, N, Alvarez, N, Pandey, A, Pasch, E, Pavlichenko, R, Pavone, A, Pawelec, E, Pechstein, G, Pelka, G, Perseo, V, Peterson, B, Pilopp, D, Pingel, S, Pisano, F, Plockl, B, Plunk, G, Poloskei, P, Pompe, B, Popov, A, Porkolab, M, Proll, J, Pueschel, M, Puiatti, M, Sitjes, A, Purps, F, Rahbarnia, K, Rasinski, M, Rasmussen, J, Reiman, A, Reimold, F, Reisner, M, Reiter, D, Richou, M, Riedl, R, Riemann, J, Risse, K, Roberg-Clark, G, Rohde, V, Romazanov, J, Rondeshagen, D, Rong, P, Rudischhauser, L, Rummel, T, Rummel, K, Runov, A, Rust, N, Ryc, L, Salembier, P, Salewski, M, Sanchez, E, Satake, S, Satheeswaran, G, Schacht, J, Scharff, E, Schauer, F, Schilling, J, Schlisio, G, Schmid, K, Schmitt, J, Schmitz, O, Schneider, W, Schneider, M, Schneider, P, Schrittwieser, R, Schroder, T, Schroder, M, Schroeder, R, Schweer, B, Schworer, D, Scott, E, Shanahan, B, Sias, G, Sichta, P, Singer, M, Sinha, P, Siplia, S, Slaby, C, Sleczka, M, Smith, H, Smoniewski, J, Sonnendrucker, E, Spolaore, M, Spring, A, Stadler, R, Stanczak, D, Stange, T, Stepanov, I, Stephey, L, Stober, J, Stroth, U, Strumberger, E, Suzuki, C, Suzuki, Y, Svensson, J, Szabolics, T, Szepesi, T, Szucs, M, Tabares, F, Tamura, N, Tancetti, A, Tantos, C, Terry, J, Thienpondt, H, Thomsen, H, Thumm, M, Travere, J, Traverso, P, Tretter, J, Trier, E, Mora, H, Tsujimura, T, Turkin, Y, Tykhyi, A, Unterberg, B, van Eeten, P, van Milligen, B, van Schoor, M, Vano, L, Varoutis, S, Vecsei, M, Vela, L, Velasco, J, Vervier, M, Vianello, N, Viebke, H, Vilbrandt, R, Vogel, G, Vogt, N, Volkhausen, C, von Stechow, A, Wagner, F, Wang, E, Wang, H, Warmer, F, Wauters, T, Wegener, L, Wegner, T, Weir, G, Wenzel, U, White, A, Wilde, F, Wilms, F, Windisch, T, Winkler, M, Winter, A, Winters, V, Wolf, R, Wright, A, Wurden, G, Xanthopoulos, P, Xu, S, Yamada, H, Yamaguchi, H, Yokoyama, M, Yoshinuma, M, Yu, Q, Zamanov, M, Zanini, M, Zarnstorff, M, Zhang, D, Zhou, S, Zhu, J, Zhu, C, Zilker, M, Zocco, A, Zohm, H, Zoletnik, S, Zsuga, L, Pedersen T. S., Abramovic I., Agostinetti P., Torres M. A., Akaslompolo S., Belloso J. A., Aleynikov P., Aleynikova K., Alhashimi M., Ali A., Allen N., Alonso A., Anda G., Andreeva T., Angioni C., Arkhipov A., Arnold A., Asad W., Ascasibar E., Aumeunier M. -H., Avramidis K., Aymerich E., Baek S. -G., Bahner J., Baillod A., Balden M., Baldzuhn J., Ballinger S., Banduch M., Bannmann S., Navarro A. B., Barbui T., Beidler C., Belafdil C., Bencze A., Benndorf A., Beurskens M., Biedermann C., Biletskyi O., Blackwell B., Blatzheim M., Bluhm T., Bockenhoff D., Bongiovi G., Borchardt M., Borodin D., Boscary J., Bosch H., Bosmann T., Boswirth B., Bottger L., Bottino A., Bozhenkov S., Brakel R., Brandt C., Brauer T., Braune H., Brezinsek S., Brunner K., Buller S., Burhenn R., Bussiahn R., Buttenschon B., Buzas A., Bykov V., Calvo I., Mata K. C., Caminal I., Cannas B., Cappa A., Carls A., Carovani F., Carr M., Carralero D., Carvalho B., Casas J., Castano-Bardawil D., Castejon F., Chaudhary N., Chelis I., Chomiczewska A., Coenen J. W., Cole M., Cordella F., Corre Y., Crombe K., Cseh G., Csillag B., Damm H., Day C., de Baar M., De la Cal E., Degenkolbe S., Demby A., Denk S., Dhard C., Di Siena A., Dinklage A., Dittmar T., Dreval M., Drevlak M., Drewelow P., Drews P., Dunai D., Edlund E., Effenberg F., Ehrke G., Endler M., Ennis D. A., Escoto F. J., Estrada T., Fable E., Fahrenkamp N., Fanni A., Faustin J., Fellinger J., Feng Y., Figacz W., Flom E., Ford O., Fornal T., Frerichs H., Freundt S., Fuchert G., Fukuyama M., Fullenbach F., Gantenbein G., Gao Y., Garcia K., Regana J. M. G., Garcia-Cortes I., Gaspar J., Gates D. A., Geiger J., Geiger B., Giudicotti L., Gonzalez A., Goriaev A., Gradic D., Grahl M., Graves J. P., Green J., Grelier E., Greuner H., Gross S., Grote H., Groth M., Gruca M., Grulke O., Grun M., Arnaiz J. G., Gunter S., Haak V., Haas M., Hacker P., Hakola A., Hallenbert A., Hammond K., Han X., Hansen S. K., Harris J. H., Hartfuss H., Hartmann D., Hathiramani D., Hatzky R., Hawke J., Hegedus S., Hein B., Heinemann B., Helander P., Henneberg S., Hergenhahn U., Hidalgo C., Hindenlang F., Hirsch M., Hofel U., Hollfeld K. P., Holtz A., Hopf D., Hoschen D., Houry M., Howard J., Huang X., Hubeny M., Hudson S., Ida K., Igitkhanov Y., Igochine V., Illy S., Ionita-Schrittwieser C., Isobe M., Jablczynska M., Jablonski S., Jagielski B., Jakubowski M., van Vuuren A. J., Jelonnek J., Jenko F., Jensen T., Jenzsch H., Junghanns P., Kaczmarczyk J., Kallmeyer J., Kamionka U., Kandler M., Kasilov S., Kazakov Y., Kennedy D., Kharwandikar A., Khokhlov M., Kiefer C., Killer C., Kirschner A., Kleiber R., Klinger T., Klose S., Knauer J., Knieps A., Kochl F., Kocsis G., Kolesnichenko Ya. I., Konies A., Konig R., Kontula J., Kornejew P., Koschinsky J., Kozulia M. M., Kramer-Flecken A., Krampitz R., Krause M., Krawczyk N., Kremeyer T., Krier L., Kriete D. M., Krychowiak M., Ksiazek I., Kubkowska M., Kuczynski M., Kuhner G., Kumar A., Kurki-Suonio T., Kwak S., Landreman M., Lang P. T., Langenberg A., Laqua H. P., Laqua H., Laube R., Lazerson S., Lewerentz M., Li C., Liang Y., Linsmeier Ch., Lion J., Litnovsky A., Liu S., Lobsien J., Loizu J., Lore J., Lorenz A., Losada U., Louche F., Lunsford R., Lutsenko V., Machielsen M., Mackel F., Maisano-Brown J., Maj O., Makowski D., Manduchi G., Maragkoudakis E., Marchuk O., Marsen S., Martines E., Martinez-Fernandez J., Marushchenko M., Masuzaki S., Maurer D., Mayer M., McCarthy K. J., McCormack O., McNeely P., Meister H., Mendelevitch B., Mendes S., Merlo A., Messian A., Mielczarek A., Mishchenko O., Missal B., Mitteau R., Moiseenko V. E., Mollen A., Moncada V., Monnich T., Morisaki T., Moseev D., Motojima G., Mulas S., Mulsow M., Nagel M., Naujoks D., Naulin V., Neelis T., Neilson H., Neu R., Neubauer O., Neuner U., Nicolai D., Nielsen S. K., Niemann H., Nishiza T., Nishizawa T., Nuhrenberg C., Ochoukov R., Oelmann J., Offermanns G., Ogawa K., Okamura S., Olmanns J., Ongena J., Oosterbeek J., Otte M., Pablant N., Alvarez N. P., Pandey A., Pasch E., Pavlichenko R., Pavone A., Pawelec E., Pechstein G., Pelka G., Perseo V., Peterson B., Pilopp D., Pingel S., Pisano F., Plockl B., Plunk G., Poloskei P., Pompe B., Popov A., Porkolab M., Proll J., Pueschel M. J., Puiatti M. -E., Sitjes A. P., Purps F., Rahbarnia K., Rasinski M., Rasmussen J., Reiman A., Reimold F., Reisner M., Reiter D., Richou M., Riedl R., Riemann J., Risse K., Roberg-Clark G., Rohde V., Romazanov J., Rondeshagen D., Rong P., Rudischhauser L., Rummel T., Rummel K., Runov A., Rust N., Ryc L., Salembier P., Salewski M., Sanchez E., Satake S., Satheeswaran G., Schacht J., Scharff E., Schauer F., Schilling J., Schlisio G., Schmid K., Schmitt J., Schmitz O., Schneider W., Schneider M., Schneider P., Schrittwieser R., Schroder T., Schroder M., Schroeder R., Schweer B., Schworer D., Scott E., Shanahan B., Sias G., Sichta P., Singer M., Sinha P., Siplia S., Slaby C., Sleczka M., Smith H., Smoniewski J., Sonnendrucker E., Spolaore M., Spring A., Stadler R., Stanczak D., Stange T., Stepanov I., Stephey L., Stober J., Stroth U., Strumberger E., Suzuki C., Suzuki Y., Svensson J., Szabolics T., Szepesi T., Szucs M., Tabares F. L., Tamura N., Tancetti A., Tantos C., Terry J., Thienpondt H., Thomsen H., Thumm M., Travere J. M., Traverso P., Tretter J., Trier E., Mora H. T., Tsujimura T., Turkin Y., Tykhyi A., Unterberg B., van Eeten P., van Milligen B. Ph., van Schoor M., Vano L., Varoutis S., Vecsei M., Vela L., Velasco J. L., Vervier M., Vianello N., Viebke H., Vilbrandt R., Vogel G., Vogt N., Volkhausen C., von Stechow A., Wagner F., Wang E., Wang H., Warmer F., Wauters T., Wegener L., Wegner T., Weir G., Wenzel U., White A., Wilde F., Wilms F., Windisch T., Winkler M., Winter A., Winters V., Wolf R., Wright A. M., Wurden G. A., Xanthopoulos P., Xu S., Yamada H., Yamaguchi H., Yokoyama M., Yoshinuma M., Yu Q., Zamanov M., Zanini M., Zarnstorff M., Zhang D., Zhou S., Zhu J., Zhu C., Zilker M., Zocco A., Zohm H., Zoletnik S., and Zsuga L.

Abstract

We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.

Published
2022

8. 602 Efficacy of autologous cell-based therapy for male and female pattern hair loss using dermal sheath cup cells: A single arm, multi-center, confirmatory clinical study

Author

Harada, K., primary, Ohyama, M., additional, Niiyama, S., additional, Irisawa, R., additional, Mae, K., additional, Mori, M., additional, Wakimoto, H., additional, Kinoshita-Ise, M., additional, Fukuyama, M., additional, Hayakawa, R., additional, Takagi, M., additional, Yamazaki, M., additional, Miyoshi, M., additional, Nishikawa, S., additional, Sato, S., additional, Nakazawa, Y., additional, Sugimoto, T., additional, Ogo, M., additional, and Tsuboi, R., additional

Published
2023
Full Text
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14. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Pedersen, Thomas Sunn, Abramovic, I., Agostinetti, P., Torres, M. Agredano, Äkäslompolo, S., Belloso, J. Alcuson, Aleynikov, P., Aleynikova, K., Alhashimi, M., Ali, A., Allen, N., Alonso, A., Anda, G., Andreeva, T., Angioni, C., Arkhipov, A., Arnold, A., Asad, W., Ascasibar, E., Aumeunier, M. H., Avramidis, K., Aymerich, E., Baek, S. G., Bähner, J., Baillod, A., Balden, M., Baldzuhn, J., Ballinger, S., Banduch, M., Bannmann, S., Navarro, A. Bañón, Barbui, T., Beidler, C., Belafdil, C., Bencze, A., Benndorf, A., Beurskens, M., Biedermann, C., Biletskyi, O., Blackwell, B., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bongiovi, G., Borchardt, M., Borodin, D., Boscary, J., Bosch, H., Bosmann, T., Böswirth, B., Böttger, L., Bottino, A., Bozhenkov, S., Brakel, R., Brandt, C., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K., Buller, S., Burhenn, R., Bussiahn, R., Buttenschön, B., Buzás, A., Bykov, V., Calvo, I., Mata, K. Camacho, Caminal, I., Cannas, B., Cappa, A., Carls, A., Carovani, F., Carr, M., Carralero, D., Carvalho, B., Casas, J., Castano-Bardawil, D., Castejon, F., Chaudhary, N., Chelis, I., Chomiczewska, A., Coenen, J. W., Cole, M., Cordella, F., Corre, Y., Crombe, K., Cseh, G., Csillag, B., Damm, H., Day, C., de Baar, M., De la Cal, E., Degenkolbe, S., Demby, A., Denk, S., Dhard, C., Di Siena, A., Dinklage, A., Dittmar, T., Dreval, M., Drevlak, M., Drewelow, P., Drews, P., Dunai, D., Edlund, E., Effenberg, F., Ehrke, G., Endler, M., Ennis, D. A., Escoto, F. J., Estrada, T., Fable, E., Fahrenkamp, N., Fanni, A., Faustin, J., Fellinger, J., Feng, Y., Figacz, W., Flom, E., Ford, O., Fornal, T., Frerichs, H., Freundt, S., Fuchert, G., Fukuyama, M., Füllenbach, F., Gantenbein, G., Gao, Y., Garcia, K., Regaña, J. M.García, García-Cortés, I., Gaspar, J., Gates, D. A., Geiger, J., Geiger, B., Giudicotti, L., González, A., Goriaev, A., Gradic, D., Grahl, M., Graves, J. P., Green, J., Grelier, E., Greuner, H., Groß, S., Grote, H., Groth, M., Gruca, M., Grulke, O., Grün, M., Arnaiz, J. Guerrero, Günter, S., Haak, V., Haas, M., Hacker, P., Hakola, A., Hallenbert, A., Hammond, K., Han, X., Hansen, S. K., Harris, J. H., Hartfuß, H., Hartmann, D., Hathiramani, D., Hatzky, R., Hawke, J., Hegedus, S., Hein, B., Heinemann, B., Helander, P., Henneberg, S., Hergenhahn, U., Hidalgo, C., Hindenlang, F., Hirsch, M., Höfel, U., Hollfeld, K. P., Holtz, A., Hopf, D., Höschen, D., Houry, M., Howard, J., Huang, X., Hubeny, M., Hudson, S., Ida, K., Igitkhanov, Y., Igochine, V., Illy, S., Ionita-Schrittwieser, C., Isobe, M., Jabłczynska, M., Jablonski, S., Jagielski, B., Jakubowski, M., van Vuuren, A. Jansen, Jelonnek, J., Jenko, F., Jensen, T., Jenzsch, H., Junghanns, P., Kaczmarczyk, J., Kallmeyer, J., Kamionka, U., Kandler, M., Kasilov, S., Kazakov, Y., Kennedy, D., Kharwandikar, A., Khokhlov, M., Kiefer, C., Killer, C., Kirschner, A., Kleiber, R., Klinger, T., Klose, S., Knauer, J., Knieps, A., Köchl, F., Kocsis, G., Kolesnichenko, Ya I., Könies, A., König, R., Kontula, J., Kornejew, P., Koschinsky, J., Kozulia, M. M., Krämer-Flecken, A., Krampitz, R., Krause, M., Krawczyk, N., Kremeyer, T., Krier, L., Kriete, D. M., Krychowiak, M., Ksiazek, I., Kubkowska, M., Kuczynski, M., Kühner, G., Kumar, A., Kurki-Suonio, T., Kwak, S., Landreman, M., Lang, P. T., Langenberg, A., Laqua, H., Laube, R., Lazerson, S., Lewerentz, M., Li, C., Liang, Y., Linsmeier, Ch, Lion, J., Litnovsky, A., Liu, S., Lobsien, J., Loizu, J., Lore, J., Lorenz, A., Losada, U., Louche, F., Lunsford, R., Lutsenko, V., Machielsen, M., Mackel, F., Maisano-Brown, J., Maj, O., Makowski, D., Manduchi, G., Maragkoudakis, E., Marchuk, O., Marsen, S., Martines, E., Martinez-Fernandez, J., Marushchenko, M., Masuzaki, S., Maurer, D., Mayer, M., McCarthy, K. J., McCormack, O., McNeely, P., Meister, H., Mendelevitch, B., Mendes, S., Merlo, A., Messian, A., Mielczarek, A., Mishchenko, O., Missal, B., Mitteau, R., Moiseenko, V. E., Mollen, A., Moncada, V., Mönnich, T., Morisaki, T., Moseev, D., Motojima, G., Mulas, S., Mulsow, M., Nagel, M., Naujoks, D., Naulin, V., Neelis, T., Neilson, H., Neu, R., Neubauer, O., Neuner, U., Nicolai, D., Nielsen, S. K., Niemann, H., Nishiza, T., Nishizawa, T., Nührenberg, C., Ochoukov, R., Oelmann, J., Offermanns, G., Ogawa, K., Okamura, S., Ölmanns, J., Ongena, J., Oosterbeek, J., Otte, M., Pablant, N., Alvarez, N. Panadero, Pandey, A., Pasch, E., Pavlichenko, R., Pavone, A., Pawelec, E., Pechstein, G., Pelka, G., Perseo, V., Peterson, B., Pilopp, D., Pingel, S., Pisano, F., Plöckl, B., Plunk, G., Pölöskei, P., Pompe, B., Popov, A., Porkolab, M., Proll, J., Pueschel, M. J., Puiatti, M. E., Sitjes, A. Puig, Purps, F., Rahbarnia, K., Rasinski, M., Rasmussen, J., Reiman, A., Reimold, F., Reisner, M., Reiter, D., Richou, M., Riedl, R., Riemann, J., Riße, K., Roberg-Clark, G., Rohde, V., Romazanov, J., Rondeshagen, D., Rong, P., Rudischhauser, L., Rummel, T., Rummel, K., Runov, A., Rust, N., Ryc, L., Salembier, P., Salewski, M., Sanchez, E., Satake, S., Satheeswaran, G., Schacht, J., Scharff, E., Schauer, F., Schilling, J., Schlisio, G., Schmid, K., Schmitt, J., Schmitz, O., Schneider, W., Schneider, M., Schneider, P., Schrittwieser, R., Schröder, T., Schröder, M., Schroeder, R., Schweer, B., Schwörer, D., Scott, E., Shanahan, B., Sias, G., Sichta, P., Singer, M., Sinha, P., Sipliä, S., Slaby, C., Sleczka, M., Smith, H., Smoniewski, J., Sonnendrücker, E., Spolaore, M., Spring, A., Stadler, R., Stanczak, D., Stange, T., Stepanov, I., Stephey, L., Stober, J., Stroth, U., Strumberger, E., Suzuki, C., Suzuki, Y., Svensson, J., Szabolics, T., Szepesi, T., Szücs, M., Tabarés, F. L., Tamura, N., Tancetti, A., Tantos, C., Terry, J., Thienpondt, H., Thomsen, H., Thumm, M., Travere, J. M., Traverso, P., Tretter, J., Trier, E., Mora, H. Trimino, Tsujimura, T., Turkin, Y., Tykhyi, A., Unterberg, B., van Eeten, P., van Milligen, B. Ph, van Schoor, M., Vano, L., Varoutis, S., Vecsei, M., Vela, L., Velasco, J. L., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vogel, G., Vogt, N., Volkhausen, C., von Stechow, A., Wagner, F., Wang, E., Wang, H., Warmer, F., Wauters, T., Wegener, L., Wegner, T., Weir, G., Wenzel, U., White, A., Wilde, F., Wilms, F., Windisch, T., Winkler, M., Winter, A., Winters, V., Wolf, R., Wright, A. M., Wurden, G. A., Xanthopoulos, P., Xu, S., Yamada, H., Yamaguchi, H., Yokoyama, M., Yoshinuma, M., Yu, Q., Zamanov, M., Zanini, M., Zarnstorff, M., Zhang, D., Zhou, S., Zhu, J., Zhu, C., Zilker, M., Zocco, A., Zohm, H., Zoletnik, S., Zsuga, L., Pedersen, Thomas Sunn, Abramovic, I., Agostinetti, P., Torres, M. Agredano, Äkäslompolo, S., Belloso, J. Alcuson, Aleynikov, P., Aleynikova, K., Alhashimi, M., Ali, A., Allen, N., Alonso, A., Anda, G., Andreeva, T., Angioni, C., Arkhipov, A., Arnold, A., Asad, W., Ascasibar, E., Aumeunier, M. H., Avramidis, K., Aymerich, E., Baek, S. G., Bähner, J., Baillod, A., Balden, M., Baldzuhn, J., Ballinger, S., Banduch, M., Bannmann, S., Navarro, A. Bañón, Barbui, T., Beidler, C., Belafdil, C., Bencze, A., Benndorf, A., Beurskens, M., Biedermann, C., Biletskyi, O., Blackwell, B., Blatzheim, M., Bluhm, T., Böckenhoff, D., Bongiovi, G., Borchardt, M., Borodin, D., Boscary, J., Bosch, H., Bosmann, T., Böswirth, B., Böttger, L., Bottino, A., Bozhenkov, S., Brakel, R., Brandt, C., Bräuer, T., Braune, H., Brezinsek, S., Brunner, K., Buller, S., Burhenn, R., Bussiahn, R., Buttenschön, B., Buzás, A., Bykov, V., Calvo, I., Mata, K. Camacho, Caminal, I., Cannas, B., Cappa, A., Carls, A., Carovani, F., Carr, M., Carralero, D., Carvalho, B., Casas, J., Castano-Bardawil, D., Castejon, F., Chaudhary, N., Chelis, I., Chomiczewska, A., Coenen, J. W., Cole, M., Cordella, F., Corre, Y., Crombe, K., Cseh, G., Csillag, B., Damm, H., Day, C., de Baar, M., De la Cal, E., Degenkolbe, S., Demby, A., Denk, S., Dhard, C., Di Siena, A., Dinklage, A., Dittmar, T., Dreval, M., Drevlak, M., Drewelow, P., Drews, P., Dunai, D., Edlund, E., Effenberg, F., Ehrke, G., Endler, M., Ennis, D. A., Escoto, F. J., Estrada, T., Fable, E., Fahrenkamp, N., Fanni, A., Faustin, J., Fellinger, J., Feng, Y., Figacz, W., Flom, E., Ford, O., Fornal, T., Frerichs, H., Freundt, S., Fuchert, G., Fukuyama, M., Füllenbach, F., Gantenbein, G., Gao, Y., Garcia, K., Regaña, J. M.García, García-Cortés, I., Gaspar, J., Gates, D. A., Geiger, J., Geiger, B., Giudicotti, L., González, A., Goriaev, A., Gradic, D., Grahl, M., Graves, J. P., Green, J., Grelier, E., Greuner, H., Groß, S., Grote, H., Groth, M., Gruca, M., Grulke, O., Grün, M., Arnaiz, J. Guerrero, Günter, S., Haak, V., Haas, M., Hacker, P., Hakola, A., Hallenbert, A., Hammond, K., Han, X., Hansen, S. K., Harris, J. H., Hartfuß, H., Hartmann, D., Hathiramani, D., Hatzky, R., Hawke, J., Hegedus, S., Hein, B., Heinemann, B., Helander, P., Henneberg, S., Hergenhahn, U., Hidalgo, C., Hindenlang, F., Hirsch, M., Höfel, U., Hollfeld, K. P., Holtz, A., Hopf, D., Höschen, D., Houry, M., Howard, J., Huang, X., Hubeny, M., Hudson, S., Ida, K., Igitkhanov, Y., Igochine, V., Illy, S., Ionita-Schrittwieser, C., Isobe, M., Jabłczynska, M., Jablonski, S., Jagielski, B., Jakubowski, M., van Vuuren, A. Jansen, Jelonnek, J., Jenko, F., Jensen, T., Jenzsch, H., Junghanns, P., Kaczmarczyk, J., Kallmeyer, J., Kamionka, U., Kandler, M., Kasilov, S., Kazakov, Y., Kennedy, D., Kharwandikar, A., Khokhlov, M., Kiefer, C., Killer, C., Kirschner, A., Kleiber, R., Klinger, T., Klose, S., Knauer, J., Knieps, A., Köchl, F., Kocsis, G., Kolesnichenko, Ya I., Könies, A., König, R., Kontula, J., Kornejew, P., Koschinsky, J., Kozulia, M. M., Krämer-Flecken, A., Krampitz, R., Krause, M., Krawczyk, N., Kremeyer, T., Krier, L., Kriete, D. M., Krychowiak, M., Ksiazek, I., Kubkowska, M., Kuczynski, M., Kühner, G., Kumar, A., Kurki-Suonio, T., Kwak, S., Landreman, M., Lang, P. T., Langenberg, A., Laqua, H., Laube, R., Lazerson, S., Lewerentz, M., Li, C., Liang, Y., Linsmeier, Ch, Lion, J., Litnovsky, A., Liu, S., Lobsien, J., Loizu, J., Lore, J., Lorenz, A., Losada, U., Louche, F., Lunsford, R., Lutsenko, V., Machielsen, M., Mackel, F., Maisano-Brown, J., Maj, O., Makowski, D., Manduchi, G., Maragkoudakis, E., Marchuk, O., Marsen, S., Martines, E., Martinez-Fernandez, J., Marushchenko, M., Masuzaki, S., Maurer, D., Mayer, M., McCarthy, K. J., McCormack, O., McNeely, P., Meister, H., Mendelevitch, B., Mendes, S., Merlo, A., Messian, A., Mielczarek, A., Mishchenko, O., Missal, B., Mitteau, R., Moiseenko, V. E., Mollen, A., Moncada, V., Mönnich, T., Morisaki, T., Moseev, D., Motojima, G., Mulas, S., Mulsow, M., Nagel, M., Naujoks, D., Naulin, V., Neelis, T., Neilson, H., Neu, R., Neubauer, O., Neuner, U., Nicolai, D., Nielsen, S. K., Niemann, H., Nishiza, T., Nishizawa, T., Nührenberg, C., Ochoukov, R., Oelmann, J., Offermanns, G., Ogawa, K., Okamura, S., Ölmanns, J., Ongena, J., Oosterbeek, J., Otte, M., Pablant, N., Alvarez, N. Panadero, Pandey, A., Pasch, E., Pavlichenko, R., Pavone, A., Pawelec, E., Pechstein, G., Pelka, G., Perseo, V., Peterson, B., Pilopp, D., Pingel, S., Pisano, F., Plöckl, B., Plunk, G., Pölöskei, P., Pompe, B., Popov, A., Porkolab, M., Proll, J., Pueschel, M. J., Puiatti, M. E., Sitjes, A. Puig, Purps, F., Rahbarnia, K., Rasinski, M., Rasmussen, J., Reiman, A., Reimold, F., Reisner, M., Reiter, D., Richou, M., Riedl, R., Riemann, J., Riße, K., Roberg-Clark, G., Rohde, V., Romazanov, J., Rondeshagen, D., Rong, P., Rudischhauser, L., Rummel, T., Rummel, K., Runov, A., Rust, N., Ryc, L., Salembier, P., Salewski, M., Sanchez, E., Satake, S., Satheeswaran, G., Schacht, J., Scharff, E., Schauer, F., Schilling, J., Schlisio, G., Schmid, K., Schmitt, J., Schmitz, O., Schneider, W., Schneider, M., Schneider, P., Schrittwieser, R., Schröder, T., Schröder, M., Schroeder, R., Schweer, B., Schwörer, D., Scott, E., Shanahan, B., Sias, G., Sichta, P., Singer, M., Sinha, P., Sipliä, S., Slaby, C., Sleczka, M., Smith, H., Smoniewski, J., Sonnendrücker, E., Spolaore, M., Spring, A., Stadler, R., Stanczak, D., Stange, T., Stepanov, I., Stephey, L., Stober, J., Stroth, U., Strumberger, E., Suzuki, C., Suzuki, Y., Svensson, J., Szabolics, T., Szepesi, T., Szücs, M., Tabarés, F. L., Tamura, N., Tancetti, A., Tantos, C., Terry, J., Thienpondt, H., Thomsen, H., Thumm, M., Travere, J. M., Traverso, P., Tretter, J., Trier, E., Mora, H. Trimino, Tsujimura, T., Turkin, Y., Tykhyi, A., Unterberg, B., van Eeten, P., van Milligen, B. Ph, van Schoor, M., Vano, L., Varoutis, S., Vecsei, M., Vela, L., Velasco, J. L., Vervier, M., Vianello, N., Viebke, H., Vilbrandt, R., Vogel, G., Vogt, N., Volkhausen, C., von Stechow, A., Wagner, F., Wang, E., Wang, H., Warmer, F., Wauters, T., Wegener, L., Wegner, T., Weir, G., Wenzel, U., White, A., Wilde, F., Wilms, F., Windisch, T., Winkler, M., Winter, A., Winters, V., Wolf, R., Wright, A. M., Wurden, G. A., Xanthopoulos, P., Xu, S., Yamada, H., Yamaguchi, H., Yokoyama, M., Yoshinuma, M., Yu, Q., Zamanov, M., Zanini, M., Zarnstorff, M., Zhang, D., Zhou, S., Zhu, J., Zhu, C., Zilker, M., Zocco, A., Zohm, H., Zoletnik, S., and Zsuga, L.

Abstract

We present recent highlights from the most recent operation phases of Wendelstein 7-X, the most advanced stellarator in the world. Stable detachment with good particle exhaust, low impurity content, and energy confinement times exceeding 100 ms, have been maintained for tens of seconds. Pellet fueling allows for plasma phases with reduced ion-temperature-gradient turbulence, and during such phases, the overall confinement is so good (energy confinement times often exceeding 200 ms) that the attained density and temperature profiles would not have been possible in less optimized devices, since they would have had neoclassical transport losses exceeding the heating applied in W7-X. This provides proof that the reduction of neoclassical transport through magnetic field optimization is successful. W7-X plasmas generally show good impurity screening and high plasma purity, but there is evidence of longer impurity confinement times during turbulence-suppressed phases.

Published
2022

15. Experimental confirmation of efficient island divertor operation and successful neoclassical transport optimization in Wendelstein 7-X

Author

Sunn Pedersen, Thomas, primary, Abramovic, I., additional, Agostinetti, P., additional, Agredano Torres, M., additional, Äkäslompolo, S., additional, Alcuson Belloso, J., additional, Aleynikov, P., additional, Aleynikova, K., additional, Alhashimi, M., additional, Ali, A., additional, Allen, N., additional, Alonso, A., additional, Anda, G., additional, Andreeva, T., additional, Angioni, C., additional, Arkhipov, A., additional, Arnold, A., additional, Asad, W., additional, Ascasibar, E., additional, Aumeunier, M.-H., additional, Avramidis, K., additional, Aymerich, E., additional, Baek, S.-G., additional, Bähner, J., additional, Baillod, A., additional, Balden, M., additional, Baldzuhn, J., additional, Ballinger, S., additional, Banduch, M., additional, Bannmann, S., additional, Banon Navarro, A., additional, Bañón Navarro, A., additional, Barbui, T., additional, Beidler, C., additional, Belafdil, C., additional, Bencze, A., additional, Benndorf, A., additional, Beurskens, M., additional, Biedermann, C., additional, Biletskyi, O., additional, Blackwell, B., additional, Blatzheim, M., additional, Bluhm, T., additional, Böckenhoff, D., additional, Bongiovi, G., additional, Borchardt, M., additional, Borodin, D., additional, Boscary, J., additional, Bosch, H., additional, Bosmann, T., additional, Böswirth, B., additional, Böttger, L., additional, Bottino, A., additional, Bozhenkov, S., additional, Brakel, R., additional, Brandt, C., additional, Bräuer, T., additional, Braune, H., additional, Brezinsek, S., additional, Brunner, K., additional, Buller, S., additional, Burhenn, R., additional, Bussiahn, R., additional, Buttenschön, B., additional, Buzás, A., additional, Bykov, V., additional, Calvo, I., additional, Camacho Mata, K., additional, Caminal, I., additional, Cannas, B., additional, Cappa, A., additional, Carls, A., additional, Carovani, F., additional, Carr, M., additional, Carralero, D., additional, Carvalho, B., additional, Casas, J., additional, Castano-Bardawil, D., additional, Castejon, F., additional, Chaudhary, N., additional, Chelis, I., additional, Chomiczewska, A., additional, Coenen, J.W., additional, Cole, M., additional, Cordella, F., additional, Corre, Y., additional, Crombe, K., additional, Cseh, G., additional, Csillag, B., additional, Damm, H., additional, Day, C., additional, de Baar, M., additional, De la Cal, E., additional, Degenkolbe, S., additional, Demby, A., additional, Denk, S., additional, Dhard, C., additional, Di Siena, A., additional, Dinklage, A., additional, Dittmar, T., additional, Dreval, M., additional, Drevlak, M., additional, Drewelow, P., additional, Drews, P., additional, Dunai, D., additional, Edlund, E., additional, Effenberg, F., additional, Ehrke, G., additional, Endler, M., additional, Ennis, D.A., additional, Escoto, F.J., additional, Estrada, T., additional, Fable, E., additional, Fahrenkamp, N., additional, Fanni, A., additional, Faustin, J., additional, Fellinger, J., additional, Feng, Y., additional, Figacz, W., additional, Flom, E., additional, Ford, O., additional, Fornal, T., additional, Frerichs, H., additional, Freundt, S., additional, Fuchert, G., additional, Fukuyama, M., additional, Füllenbach, F., additional, Gantenbein, G., additional, Gao, Y., additional, Garcia, K., additional, García Regaña, J.M., additional, García-Cortés, I., additional, Gaspar, J., additional, Gates, D.A., additional, Geiger, J., additional, Geiger, B., additional, Giudicotti, L., additional, González, A., additional, Goriaev, A., additional, Gradic, D., additional, Grahl, M., additional, Graves, J.P., additional, Green, J., additional, Grelier, E., additional, Greuner, H., additional, Groß, S., additional, Grote, H., additional, Groth, M., additional, Gruca, M., additional, Grulke, O., additional, Grün, M., additional, Guerrero Arnaiz, J., additional, Günter, S., additional, Haak, V., additional, Haas, M., additional, Hacker, P., additional, Hakola, A., additional, Hallenbert, A., additional, Hammond, K., additional, Han, X., additional, Hansen, S.K., additional, Harris, J.H., additional, Hartfuß, H., additional, Hartmann, D., additional, Hathiramani, D., additional, Hatzky, R., additional, Hawke, J., additional, Hegedus, S., additional, Hein, B., additional, Heinemann, B., additional, Helander, P., additional, Henneberg, S., additional, Hergenhahn, U., additional, Hidalgo, C., additional, Hindenlang, F., additional, Hirsch, M., additional, Höfel, U., additional, Hollfeld, K.P., additional, Holtz, A., additional, Hopf, D., additional, Höschen, D., additional, Houry, M., additional, Howard, J., additional, Huang, X., additional, Hubeny, M., additional, Hudson, S., additional, Ida, K., additional, Igitkhanov, Y., additional, Igochine, V., additional, Illy, S., additional, Ionita-Schrittwieser, C., additional, Isobe, M., additional, Jabłczyńska, M., additional, Jablonski, S., additional, Jagielski, B., additional, Jakubowski, M., additional, Jansen van Vuuren, A., additional, Jelonnek, J., additional, Jenko, F., additional, Jensen, T., additional, Jenzsch, H., additional, Junghanns, P., additional, Kaczmarczyk, J., additional, Kallmeyer, J., additional, Kamionka, U., additional, Kandler, M., additional, Kasilov, S., additional, Kazakov, Y., additional, Kennedy, D., additional, Kharwandikar, A., additional, Khokhlov, M., additional, Kiefer, C., additional, Killer, C., additional, Kirschner, A., additional, Kleiber, R., additional, Klinger, T., additional, Klose, S., additional, Knauer, J., additional, Knieps, A., additional, Köchl, F., additional, Kocsis, G., additional, Kolesnichenko, Ya.I., additional, Könies, A., additional, König, R., additional, Kontula, J., additional, Kornejew, P., additional, Koschinsky, J., additional, Kozulia, M.M., additional, Krämer-Flecken, A., additional, Krampitz, R., additional, Krause, M., additional, Krawczyk, N., additional, Kremeyer, T., additional, Krier, L., additional, Kriete, D.M., additional, Krychowiak, M., additional, Ksiazek, I., additional, Kubkowska, M., additional, Kuczynski, M., additional, Kühner, G., additional, Kumar, A., additional, Kurki-Suonio, T., additional, Kwak, S., additional, Landreman, M., additional, Lang, P.T., additional, Langenberg, A., additional, Laqua, H.P., additional, Laqua, H., additional, Laube, R., additional, Lazerson, S., additional, Lewerentz, M., additional, Li, C., additional, Liang, Y., additional, Linsmeier, Ch., additional, Lion, J., additional, Litnovsky, A., additional, Liu, S., additional, Lobsien, J., additional, Loizu, J., additional, Lore, J., additional, Lorenz, A., additional, Losada, U., additional, Louche, F., additional, Lunsford, R., additional, Lutsenko, V., additional, Machielsen, M., additional, Mackel, F., additional, Maisano-Brown, J., additional, Maj, O., additional, Makowski, D., additional, Manduchi, G., additional, Maragkoudakis, E., additional, Marchuk, O., additional, Marsen, S., additional, Martines, E., additional, Martinez-Fernandez, J., additional, Marushchenko, M., additional, Masuzaki, S., additional, Maurer, D., additional, Mayer, M., additional, McCarthy, K.J., additional, Mccormack, O., additional, McNeely, P., additional, Meister, H., additional, Mendelevitch, B., additional, Mendes, S., additional, Merlo, A., additional, Messian, A., additional, Mielczarek, A., additional, Mishchenko, O., additional, Missal, B., additional, Mitteau, R., additional, Moiseenko, V.E., additional, Mollen, A., additional, Moncada, V., additional, Mönnich, T., additional, Morisaki, T., additional, Moseev, D., additional, Motojima, G., additional, Mulas, S., additional, Mulsow, M., additional, Nagel, M., additional, Naujoks, D., additional, Naulin, V., additional, Neelis, T., additional, Neilson, H., additional, Neu, R., additional, Neubauer, O., additional, Neuner, U., additional, Nicolai, D., additional, Nielsen, S.K., additional, Niemann, H., additional, Nishiza, T., additional, Nishizawa, T., additional, Nührenberg, C., additional, Ochoukov, R., additional, Oelmann, J., additional, Offermanns, G., additional, Ogawa, K., additional, Okamura, S., additional, Ölmanns, J., additional, Ongena, J., additional, Oosterbeek, J., additional, Otte, M., additional, Pablant, N., additional, Panadero Alvarez, N., additional, Pandey, A., additional, Pasch, E., additional, Pavlichenko, R., additional, Pavone, A., additional, Pawelec, E., additional, Pechstein, G., additional, Pelka, G., additional, Perseo, V., additional, Peterson, B., additional, Pilopp, D., additional, Pingel, S., additional, Pisano, F., additional, Plöckl, B., additional, Plunk, G., additional, Pölöskei, P., additional, Pompe, B., additional, Popov, A., additional, Porkolab, M., additional, Proll, J., additional, Pueschel, M.J., additional, Puiatti, M.-E., additional, Puig Sitjes, A., additional, Purps, F., additional, Rahbarnia, K., additional, Rasiński, M., additional, Rasmussen, J., additional, Reiman, A., additional, Reimold, F., additional, Reisner, M., additional, Reiter, D., additional, Richou, M., additional, Riedl, R., additional, Riemann, J., additional, Riße, K., additional, Roberg-Clark, G., additional, Rohde, V., additional, Romazanov, J., additional, Rondeshagen, D., additional, Rong, P., additional, Rudischhauser, L., additional, Rummel, T., additional, Rummel, K., additional, Runov, A., additional, Rust, N., additional, Ryc, L., additional, Salembier, P., additional, Salewski, M., additional, Sanchez, E., additional, Satake, S., additional, Satheeswaran, G., additional, Schacht, J., additional, Scharff, E., additional, Schauer, F., additional, Schilling, J., additional, Schlisio, G., additional, Schmid, K., additional, Schmitt, J., additional, Schmitz, O., additional, Schneider, W., additional, Schneider, M., additional, Schneider, P., additional, Schrittwieser, R., additional, Schröder, T., additional, Schröder, M., additional, Schroeder, R., additional, Schweer, B., additional, Schwörer, D., additional, Scott, E., additional, Shanahan, B., additional, Sias, G., additional, Sichta, P., additional, Singer, M., additional, Sinha, P., additional, Sipliä, S., additional, Slaby, C., additional, Sleczka, M., additional, Smith, H., additional, Smoniewski, J., additional, Sonnendrücker, E., additional, Spolaore, M., additional, Spring, A., additional, Stadler, R., additional, Stańczak, D., additional, Stange, T., additional, Stepanov, I., additional, Stephey, L., additional, Stober, J., additional, Stroth, U., additional, Strumberger, E., additional, Suzuki, C., additional, Suzuki, Y., additional, Svensson, J., additional, Szabolics, T., additional, Szepesi, T., additional, Szücs, M., additional, Tabarés, F.L., additional, Tamura, N., additional, Tancetti, A., additional, Tantos, C., additional, Terry, J., additional, Thienpondt, H., additional, Thomsen, H., additional, Thumm, M., additional, Travere, J.M., additional, Traverso, P., additional, Tretter, J., additional, Trier, E., additional, Trimino Mora, H., additional, Tsujimura, T., additional, Turkin, Y., additional, Tykhyi, A., additional, Unterberg, B., additional, van Eeten, P., additional, van Milligen, B.Ph., additional, van Schoor, M., additional, Vano, L., additional, Varoutis, S., additional, Vecsei, M., additional, Vela, L., additional, Velasco, J.L., additional, Vervier, M., additional, Vianello, N., additional, Viebke, H., additional, Vilbrandt, R., additional, Vogel, G., additional, Vogt, N., additional, Volkhausen, C., additional, von Stechow, A., additional, Wagner, F., additional, Wang, E., additional, Wang, H., additional, Warmer, F., additional, Wauters, T., additional, Wegener, L., additional, Wegner, T., additional, Weir, G., additional, Wenzel, U., additional, White, A., additional, Wilde, F., additional, Wilms, F., additional, Windisch, T., additional, Winkler, M., additional, Winter, A., additional, Winters, V., additional, Wolf, R., additional, Wright, A.M., additional, Wurden, G.A., additional, Xanthopoulos, P., additional, Xu, S., additional, Yamada, H., additional, Yamaguchi, H., additional, Yokoyama, M., additional, Yoshinuma, M., additional, Yu, Q., additional, Zamanov, M., additional, Zanini, M., additional, Zarnstorff, M., additional, Zhang, D., additional, Zhou, S., additional, Zhu, J., additional, Zhu, C., additional, Zilker, M., additional, Zocco, A., additional, Zohm, H., additional, Zoletnik, S., additional, and Zsuga, L., additional

Published
2022
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24. Gastrointestinal tissue‐based molecular biomarkers: A practical categorization based on the 2019 WHO Classification of Epithelial Digestive Tumours

Author

Quezada‐marín, J., Lam, Ak., Ochiai, A., Odze, R., Washington, Mk., Fukuyama, M., Rugge, M., Kimstra, Ds., Nagtegaal, Id., Tan, Ph., Arends, Mark J, Goldblum, Jr., Cree, Ia., and Salto‐tellez, M.

Subjects
WHO, Gastro intestinal Neoplasms, Genomics, Molecular Pathology, Biomarkers
Abstract

Molecular biomarkers have become one of the cornerstones of oncological pathology. The method of classification not only directly affects the manner in which patients are diagnosed and treated, but also guide the development of drugs and of artificial intelligence tools. This work aims to organize and update gastrointestinal molecular biomarkers in order to produce an easy-to-use guide for routine diagnostics. For this purpose, we have extracted and re-organized the molecular information of epithelial neoplasms included in the new “WHO Classification of Tumours of the Digestive System” book (5th Edition 2019).

Published
2020

27. Non-inductive plasma current ramp-up through oblique injection of harmonic electron cyclotron waves on the QUEST spherical tokamak

Author

Onchi, T., primary, Idei, H., additional, Fukuyama, M., additional, Ogata, D., additional, Ashida, R., additional, Kariya, T., additional, Ejiri, A., additional, Matsuzaki, K., additional, Osawa, Y., additional, Peng, Y., additional, Kojima, S., additional, Watanabe, O., additional, Hasegawa, M., additional, Nakamura, K., additional, Kuroda, K., additional, Ikezoe, R., additional, Ido, T., additional, Hanada, K., additional, Bertelli, N., additional, Ono, M., additional, and Fukuyama, A., additional

Published
2021
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32. P2865Mutation specific clinical characteristics in long QT syndrome type 8; severe phenotype in Timothy syndrome patients

Author

Ohno, S, primary, Yoshinaga, M, additional, Ozawa, J, additional, Fukuyama, M, additional, Seiichi, S, additional, Kashiwa, A, additional, Yasuda, K, additional, Kaneko, S, additional, Nakau, K, additional, Inukai, S, additional, Sakazaki, H, additional, Makiyama, T, additional, Aiba, T, additional, Suzuki, H, additional, and Horie, M, additional

Published
2019
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35. Time-resolved electrochemical measurement device for microscopic liquid interfaces during droplet formation

Author

Fukuyama, M., Yoshida, Y., Eijkel, J. C. T., van den Berg, A., and Hibara, Akihide

Subjects
ion transfer, liquid/liquid interface, IR-87137, Microfluidics, Micro-fluidics, Analytical chemistry, microfluidics, Ionic bonding, Electrolyte, Electrochemistry, channels, Ion, chemistry.chemical_compound, Materials Chemistry, Molecule, Aqueous solution, Tetraphenylborate, liquid/liquid interfaces, Condensed Matter Physics, EWI-23635, Electronic, Optical and Magnetic Materials, electrochemical measurement, METIS-297801, chemistry, adsorption, flow, microdroplet formation, systems, microdroplets, nitrobenzene, microchannel emulsification
Abstract

An electrochemical measurement system with a high-speed camera for observation of dynamic behavior of ionic molecules at a water-in-oil interface during microfluidic droplet formation is described. In order to demonstrate the usefulness of the system, a liquid interface between 1 M sodium chloride aqueous solution and 0.02 M tetrabutylammonium tetraphenylborate 1,2-dichloroethane solution was investigated. During aqueous droplet formation in a microfluidic device, averaged and dynamic currents between the two phases were measured under potential control. The measured current corresponded to the transport of electrolyte ions to form the electrical double layer at the liquid interface. When an 18-mu m-sized droplet was formed in each 1.2 ms, the amount of charge on each droplet was measured to be 20 pC at 0.4 V and negligible at the potential of zero charge (0.19 V). In addition, the high-speed camera observations revealed that the charge affects the stability of the droplet during and/or just after the generation process. This measurement system is expected to facilitate a fuller understanding of the droplet formation process.

Published
2013

42. Early Oligocene partial melting via biotite dehydration melting and prolonged low-pressure–low-temperature metamorphism of the upper High Himalaya Crystalline Sequence in the far east of Nepal

Author

Imayama, T., Takeshita, T., Yi, K., and Fukuyama, M.

Abstract

Early Oligocene partial melting and prolonged low-pressure–low-temperature (low-P/T) metamorphism were investigated in migmatites and orthogneisses from the upper High Himalaya Crystalline Sequence (HHCS) in the far east of Nepal. The migmatites were formed by biotite dehydration melting at c.800°C from 33 to 25 Ma. Cordierite was only produced at shallow crustal levels at pressures <6 kbar. After Early Oligocene partial melting, the low-P/T metamorphism continued until 17 Ma during exhumation of the cordierite-bearing migmatites. Early Oligocene biotite dehydration melting in the upper HHCS occurred at different times and locations from the Early Miocene muscovite dehydration melting in the underlying HHCS and the metamorphic discontinuity was accompanied by thrusting of the High Himalayan Discontinuity at c.27–19 Ma. Pervasive partial melting and prolonged low-P/T metamorphism in the upper HHCS is more compatible with a lateral southwards channel flow of the upper HHCS along the High Himalayan Discontinuity, whereas current channel flow models explaining the exhumation of the HHCS as driven only by the coupled activity of the Main Central Thrust and South Tibetan Detachment have faced difficulties in explaining the timing of the low-P/T metamorphism observed in the upper HHCS.Supplementary material:The representative cordierite compositions from the cordierite migmatites, the far east of Nepal are available at https://doi.org/10.6084/m9.figshare.c.4068815

Published
2019
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44. Electrochemical analysis of microdroplet formation

Author

Fukuyama, M., Yoshida, Y., Eijkel, Jan C.T., van den Berg, Albert, Hibara, A., Fujii, T., Takeuchi, S., and Fukuba, T.

Subjects
EWI-22754, METIS-293271, IR-83547
Abstract

This paper reports an electrochemical measurement system with a high-speed camera for observation of molecular transport phenomena at a water-oil (W/O) interface during microfluidic droplet formation. For demonstration of the system, currents corresponding to the transport of electrolyte ions to form the electrical double layer at the liquid interface were measured. Additionally, the high-speed camera observation revealed charge-effect on droplet stability during and/or just after the formation. This measurement system is expected to facilitate a full understanding of the droplet formation process.

Published
2012

47. The formation of rodingite in the Nagasaki metamorphic rocks at Nomo Peninsula, Kyushu, Japan – Zircon U–Pb and Hf isotopes and trace element evidence

Author

Fukuyama, M., Ogasawara, M., Dunkley, Daniel, Wang, K., Lee, D., Hokada, T., Maki, K., Hirata, T., Kon, Y., Fukuyama, M., Ogasawara, M., Dunkley, Daniel, Wang, K., Lee, D., Hokada, T., Maki, K., Hirata, T., and Kon, Y.

Abstract

Rodingites occur in serpentine-matrix mélange of the Nagasaki metamorphic rocks in Japan. Two types of rodingites can be distinguished on the basis of their mode of occurrence and mineralogical composition. One occurs as dikes, which contain a mineral assemblage of grossular, vesuvianite, diopside, apatite, titanite, and zircon. The other occurs as a block, which consists of zoisite, clinozoisite, diopside, chlorite, apatite, titanite, and zircon. The former type of rodingites posses two types of zircons: prismatic and porous. The prismatic zircons contain primary fluid inclusions indicating their crystallization in the presence of fluids. The porous zircons have extensive fractures filled by zircon, which are indicative of a hydrothermal origin. Both zircon types were thought to have formed under the influence of fluids. U–Pb ion probe analyses of prismatic zircons from the rodingites yield a weighted mean age of 108–105 Ma, suggesting the Early Cretaceous as the time of rodingitization in the subduction zone. Hafnium isotopic compositions of prismatic zircons are close to or overlap with the mid ocean ridge basalt (MORB) Hf isotopic ratio. This indicates that the fluid composition may have been reflected by the MORB composition during rodingitization. On the other hand, the low εHf values (11.8–18.9) of porous zircons suggest that they incorporate a small amount of Hf from fluid contaminated by subducted sediments. The rodingites are significantly enriched in Sr and depleted in large ion lithophile elements (LILE) (Cs, Rb, Ba). The fluid during rodingitization is able to extracts LILEs from the protolith of rodingites and adds Sr to the protolith of rodingites. The high field strength elements (HFSE) (Zr, Th, U, Nb, Ta) concentrations in the rodingites are similar to those of MORB, thus indicate their relatively immobile nature during rodingitization.

Published
2014

48. Brugada syndrome in spinal and bulbar muscular atrophy

Author

Araki, A., primary, Katsuno, M., additional, Suzuki, K., additional, Banno, H., additional, Suga, N., additional, Hashizume, A., additional, Mano, T., additional, Hijikata, Y., additional, Nakatsuji, H., additional, Watanabe, H., additional, Yamamoto, M., additional, Makiyama, T., additional, Ohno, S., additional, Fukuyama, M., additional, Morimoto, S.-i., additional, Horie, M., additional, and Sobue, G., additional

Published
2014
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50. Characteristics of fluid coexisting with granitoids associated with Miocene iron-copper-lead-zinc mineralisation of the Chichibu skarn deposit, Japan.

Author

Ishiyama D., PACRIM congress 2008 Gold Coast, Queensland, Australia 24-Nov-0826-Nov-08, Fukuyama M., Miyata M., Mizuta T., Ogasawara M., Satoh H., Ishiyama D., PACRIM congress 2008 Gold Coast, Queensland, Australia 24-Nov-0826-Nov-08, Fukuyama M., Miyata M., Mizuta T., Ogasawara M., and Satoh H.

Abstract

The Miocene Chichibu iron-copper-lead-zinc skarn deposit is located 100 km north west of Tokyo, Japan. Cathodoluminescence studies on fluid inclusions in quartz within the granitoids associated with the deposit showed that the composition of the fluids changed from low to high salinity as the crystals were formed. It is possible that the high- salinity fluids were associated with the mineralisation of the deposit., The Miocene Chichibu iron-copper-lead-zinc skarn deposit is located 100 km north west of Tokyo, Japan. Cathodoluminescence studies on fluid inclusions in quartz within the granitoids associated with the deposit showed that the composition of the fluids changed from low to high salinity as the crystals were formed. It is possible that the high- salinity fluids were associated with the mineralisation of the deposit.

Published
2008

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