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133 results on '"Fukushima, Kenichi"'

2. Dual antithrombotic therapy with oral anticoagulant and P2Y12 inhibitors in patients with atrial fibrillation after percutaneous coronary intervention

Author

Kitahara, Hideki, Yamashita, Daichi, Sato, Takanori, Suzuki, Sakuramaru, Hiraga, Takashi, Yamazaki, Tatsuro, Matsumoto, Tadahiro, Kobayashi, Takahiro, Ohno, Yuji, Harada, Junya, Fukushima, Kenichi, Asano, Tatsuhiko, Ishio, Naoki, Uchiyama, Raita, Miyahara, Hirofumi, Okino, Shinichi, Sano, Masanori, Kuriyama, Nehiro, Yamamoto, Masashi, Sakamoto, Naoya, Kanda, Junji, and Kobayashi, Yoshio

Published
2023
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6. Relationship between body mass index and clinical events in patients with atrial fibrillation undergoing percutaneous coronary intervention.

Author

Yamazaki, Tatsuro, Kitahara, Hideki, Yamashita, Daichi, Sato, Takanori, Suzuki, Sakuramaru, Hiraga, Takashi, Matsumoto, Tadahiro, Kobayashi, Takahiro, Ohno, Yuji, Harada, Junya, Fukushima, Kenichi, Asano, Tatsuhiko, Ishio, Naoki, Uchiyama, Raita, Miyahara, Hirofumi, Okino, Shinichi, Sano, Masanori, Kuriyama, Nehiro, Yamamoto, Masashi, and Sakamoto, Naoya

Subjects
MAJOR adverse cardiovascular events, PERCUTANEOUS coronary intervention, BODY mass index, CORONARY artery disease, ORAL medication, PRASUGREL
Abstract

Background: It is still unclear whether body mass index (BMI) affects bleeding and cardiovascular events in patients requiring oral anticoagulants (OAC) for atrial fibrillation (AF) and antiplatelet agents after percutaneous coronary intervention (PCI) for coronary artery disease (CAD). The aim of this study was to evaluate the relationship between BMI and clinical events in patients who underwent PCI under OAC therapy for AF. Method: This was a multicenter, observational cohort study conducted at 15 institutions in Japan. AF patients who underwent PCI with drug-eluting stents for CAD were retrospectively and prospectively included. Patients were divided into the Group 1 (BMI <21.3 kg/m2) and the Group 2 (BMI ≥21.3 kg/m2) according to the first-quartile value of BMI. The primary endpoint was net adverse clinical events (NACE), a composite of major adverse cardiovascular events (MACE) and major bleeding events within one year after index PCI procedure. Results: In the 720 patients, 180 patients (25.0%) had BMI value <21.3 kg/m2. While the rates of NACE and MACE were significantly higher in the Group 1 than the counterpart (21.1% vs. 11.9%, p = 0.003 and 17.2% vs. 8.9%, p = 0.004), that of major bleeding did not differ significantly between the 2 groups (5.6% vs. 4.3%, p = 0.54). The cumulative rate of NACE and MACE was significantly higher in the Group 1 than the Group 2 (both log-rank p = 0.002), although that of major bleeding events was equivalent between the 2 groups (log-rank p = 0.41). In multivariable Cox regression analyses, while BMI value <21.3 kg/m2 was not associated with major bleeding events, that cut-off value was an independent predictor for increased NACE and MACE. Conclusions: Among the patients undergoing PCI for CAD and requiring OAC for AF, BMI value was a useful indicator to predict major adverse clinical events. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Peripartum cardiomyopathy in patients with psychiatric disorders successfully treated with bromocriptine: Two case reports.

Author

Takanaka, Haruka, Ono, Ryohei, Kato, Hirotoshi, Iwahana, Togo, Miyahara, Tomoki, Takahashi, Hidehisa, Hori, Yasuhiko, Fukushima, Kenichi, and Kobayashi, Yoshio

Abstract

Peripartum cardiomyopathy (PPCM) is a rare disorder in which left ventricular systolic dysfunction and heart failure symptoms occur during the peripartum period. Inhibition of prolactin secretion by bromocriptine mediates beneficial effects on cardiac function in PPCM. Mental disorders are also associated with the onset of PPCM. Psychiatric medications for mental disorders would affect serotonin production and tryptophan and dopamine metabolism, and they are associated with PPCM. Conversely, bromocriptine affects psychiatric symptoms; therefore, the treatment of PPCM complicated by mental disorders using bromocriptine may be difficult. Herein, we report cases of two patients with PPCM and mental disorders successfully treated with bromocriptine therapy. The first case involved a 33-year-old woman with a history of atypical depression and anxiety disorder, who developed PPCM with a left ventricular ejection fraction (LVEF) of 19 %. The second case was that of a 42-year-old woman with a history of bipolar and panic disorders who developed PPCM with an LVEF of 18 %. Both patients were administered bromocriptine; however, psychiatric symptoms did not worsen and cardiac function improved. We also review the literature on the relationship between PPCM and mental disorders. Mental disorders and psychiatric medications may be associated with the onset of peripartum cardiomyopathy (PPCM). Although bromocriptine has beneficial effects on PPCM, it has also been reported to increase the risk of worsening psychiatric symptoms; therefore, the efficacy and safety of bromocriptine in PPCM patients with mental disorders is controversial. Our cases showed that bromocriptine can be used safely without worsening psychiatric symptoms in PPCM with mental disorders. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Implantable cardioverter-defibrillator therapy after resuscitation from cardiac arrest in vasospastic angina: A retrospective study

Author

Tateishi, Kazuya, primary, Kondo, Yusuke, additional, Saito, Yuichi, additional, Kitahara, Hideki, additional, Fukushima, Kenichi, additional, Takahashi, Hidehisa, additional, Yamashita, Daichi, additional, Ohashi, Koichi, additional, Suzuki, Ko, additional, Hashimoto, Osamu, additional, Sakai, Yoshiaki, additional, and Kobayashi, Yoshio, additional

Published
2022
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35. ホールスラスタ内部プラズマの数値計算と性能の経年変化予測

Author

Agata, Hiroaki, Fukushima, Kenichi, Omori, Shigeki, Tahara, Hirokazu, Sakurai, Osamu, Taniguchi, Syohei, and Maeno, Yasunobu

Abstract

平成19年度宇宙輸送シンポジウム（2008年1月28日-29日. 宇宙航空研究開発機構宇宙科学研究本部）, 相模原市, 神奈川県, Space Transportation Symposium FY2007 (January 28-29, 2008. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, 資料番号: SA6000004091

Published
2008

36. ホールスラスタ性能の経年変化に関する研究

Author

Fukushima, Kenichi, Omori, Shigeki, Agata, Hiroaki, Tahara, Hirokazu, Sakurai, Osamu, Taniguchi, Syohei, and Maeno, Yasunobu

Abstract

平成19年度宇宙輸送シンポジウム（2008年1月28日-29日. 宇宙航空研究開発機構宇宙科学研究本部）, 相模原市, 神奈川県, Space Transportation Symposium FY2007 (January 28-29, 2008. Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency (JAXA)(ISAS)), Sagamihara, Kanagawa Japan, 資料番号: SA6000004090

Published
2008

38. Quantifying the Welfare Gains from Flexible Dynamic Income Tax Systems

Author

Fukushima, Kenichi and 社会科学の高度統計・実証分析拠点構築 = Research Unit for Statistical and Empirical Analysis in Social Sciences

Abstract

This paper sets up an overlapping generations general equilibrium model with incomplete markets similar to Conesa, Kitao, and Krueger's (2009) and uses it to simulate a policy reform which replaces an optimal at tax with an optimal non-linear tax that is allowed to be arbitrarily age and history dependent. The reform shifts labor supply toward productive households and thereby increases aggregate productivity. This leads to a large increase in per capita consumption and a moderate increase in per capita hours. Under a utilitarian social welfare function that places equal weight on all current and future cohorts, the implied welfare gain amounts to more than 10% in lifetime consumption equivalents., グローバルCOEプログラム = Global COE Program

Published
2011

49. Survey on Self-management of Diabetes by Patients-With Major Purpose to Determine Usage of Insulin Preparations when Eating out-

Author

Kawasaki, Hirofumi, primary, Nakamura, Akiko, additional, Maezima, Yuriko, additional, Izumida, Mayuko, additional, Ohta, Kimiko, additional, Mori, Miwako, additional, Yamaguchi, Hiroyuki, additional, Yamakawa, Kenichi, additional, Fukushima, Kenichi, additional, Mazima, Takashi, additional, Suzuki, Akito, additional, and Hirai, Masami, additional

Published
2006
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