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20 results on '"Fukui, Shiho"'

4. Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer

Author

Kikuchi-Koike, Ryoko, Nagasaka, Kazunori, Tsuda, Hitoshi, Ishii, Yasuyuki, Sakamoto, Masaru, Kikuchi, Yoshihiro, Fukui, Shiho, Miyagawa, Yuko, Hiraike, Haruko, Kobayashi, Takayuki, Kinoshita, Takayuki, Kanai, Yae, Shibata, Tatsuhiro, Imoto, Issei, Inazawa, Johji, Matsubara, Osamu, and Ayabe, Takuya

Published
2019
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5. Serum vascular endothelial growth factor associated with the progression of granulosa cell tumor: A report of two cases

Author

Takasaki, Kazuki, primary, Ichinose, Takayuki, additional, Miyagawa, Yuko, additional, Fukui, Shiho, additional, Hashimoto, Kei, additional, Takahashi, Yuko, additional, Nishida, Haruka, additional, Hirano, Mana, additional, Hiraike, Haruko, additional, Saito, Koji, additional, Sasajima, Yuko, additional, and Nagasaka, Kazunori, additional

Published
2022
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7. The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer

Author

Fukui, Shiho, primary, Nagasaka, Kazunori, additional, Miyagawa, Yuko, additional, Kikuchi-Koike, Ryoko, additional, Kawata, Yoshiko, additional, Kanda, Ranka, additional, Ichinose, Takayuki, additional, Sugihara, Takeru, additional, Hiraike, Haruko, additional, Wada-Hiraike, Osamu, additional, Sasajima, Yuko, additional, and Ayabe, Takuya, additional

Published
2019
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8. Mechanistic Study on Allylic Arylation in Water with Linear Polystyrene-Stabilized Pd and PdO Nanoparticles

Author

Ohtaka, Atsushi, primary, Kawase, Misa, additional, Usami, Akira, additional, Fukui, Shiho, additional, Yamashita, Mana, additional, Yamaguchi, Kazuki, additional, Sakon, Akira, additional, Shiraki, Tomoya, additional, Ishida, Taiki, additional, Nagata, Soma, additional, Kimura, Yuji, additional, Hamasaka, Go, additional, Uozumi, Yasuhiro, additional, Shinagawa, Tsutomu, additional, Shimomura, Osamu, additional, and Nomura, Ryôki, additional

Published
2019
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11. Evaluation of combinations ofin vitrosensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization

Author

Hirota, Morihiko, primary, Fukui, Shiho, additional, Okamoto, Kenji, additional, Kurotani, Satoru, additional, Imai, Noriyasu, additional, Fujishiro, Miyuki, additional, Kyotani, Daiki, additional, Kato, Yoshinao, additional, Kasahara, Toshihiko, additional, Fujita, Masaharu, additional, Toyoda, Akemi, additional, Sekiya, Daisuke, additional, Watanabe, Shinichi, additional, Seto, Hirokazu, additional, Takenouchi, Osamu, additional, Ashikaga, Takao, additional, and Miyazawa, Masaaki, additional

Published
2015
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12. Test battery with the human cell line activation test, direct peptide reactivity assay and DEREK based on a 139 chemical data set for predicting skin sensitizing potential and potency of chemicals

Author

Takenouchi, Osamu, primary, Fukui, Shiho, additional, Okamoto, Kenji, additional, Kurotani, Satoru, additional, Imai, Noriyasu, additional, Fujishiro, Miyuki, additional, Kyotani, Daiki, additional, Kato, Yoshinao, additional, Kasahara, Toshihiko, additional, Fujita, Masaharu, additional, Toyoda, Akemi, additional, Sekiya, Daisuke, additional, Watanabe, Shinichi, additional, Seto, Hirokazu, additional, Hirota, Morihiko, additional, Ashikaga, Takao, additional, and Miyazawa, Masaaki, additional

Published
2015
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13. Fetal and neonatal exposure to three typical environmental chemicals with different mechanisms of action: Mixed exposure to phenol, phthalate, and dioxin cancels the effects of sole exposure on mouse midbrain dopaminergic nuclei

Author

Tanida, Takashi, primary, Warita, Katsuhiko, additional, Ishihara, Kana, additional, Fukui, Shiho, additional, Mitsuhashi, Tomoko, additional, Sugawara, Teruo, additional, Tabuchi, Yoshiaki, additional, Nanmori, Takashi, additional, Qi, Wang-Mei, additional, Inamoto, Tetsurou, additional, Yokoyama, Toshifumi, additional, Kitagawa, Hiroshi, additional, and Hoshi, Nobuhiko, additional

Published
2009
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14. Evaluation of combinations of in vitro sensitization test descriptors for the artificial neural network-based risk assessment model of skin sensitization.

Author

Hirota, Morihiko, Fukui, Shiho, Okamoto, Kenji, Kurotani, Satoru, Imai, Noriyasu, Fujishiro, Miyuki, Kyotani, Daiki, Kato, Yoshinao, Kasahara, Toshihiko, Fujita, Masaharu, Toyoda, Akemi, Sekiya, Daisuke, Watanabe, Shinichi, Seto, Hirokazu, Takenouchi, Osamu, Ashikaga, Takao, and Miyazawa, Masaaki

Subjects
SKIN tests, HUMAN cell culture, PEPTIDE analysis, BIOLOGICAL assay of antioxidants, LYMPH nodes, PREDICTION models, ARTIFICIAL neural networks
Abstract

The skin sensitization potential of chemicals has been determined with the use of the murine local lymph node assay (LLNA). However, in recent years public concern about animal welfare has led to a requirement for non-animal risk assessment systems for the prediction of skin sensitization potential, to replace LLNA. Selection of an appropriate in vitro test or in silico model descriptors is critical to obtain good predictive performance. Here, we investigated the utility of artificial neural network (ANN) prediction models using various combinations of descriptors from several in vitro sensitization tests. The dataset, collected from published data and from experiments carried out in collaboration with the Japan Cosmetic Industry Association (JCIA), consisted of values from the human cell line activation test (h-CLAT), direct peptide reactivity assay (DPRA), SH test and antioxidant response element (ARE) assay for chemicals whose LLNA thresholds have been reported. After confirming the relationship between individual in vitro test descriptors and the LLNA threshold (e.g. EC3 value), we used the subsets of chemicals for which the requisite test values were available to evaluate the predictive performance of ANN models using combinations of h-CLAT/DPRA ( N = 139 chemicals), the DPRA/ARE assay ( N = 69), the SH test/ARE assay ( N = 73), the h-CLAT/DPRA/ARE assay ( N = 69) and the h-CLAT/SH test/ARE assay ( N = 73). The h-CLAT/DPRA, h-CLAT/DPRA/ARE assay and h-CLAT/SH test/ARE assay combinations showed a better predictive performance than the DPRA/ARE assay and the SH test/ARE assay. Our data indicates that the descriptors evaluated in this study were all useful for predicting human skin sensitization potential, although combinations containing h-CLAT (reflecting dendritic cell-activating ability) were most effective for ANN-based prediction. Copyright © 2015 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Published
2015
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16. チュウゴク ノ ダイガクセイ ノ アイチャク スタイル ガ ユウジョウ ノ シツ ニ アタエル エイキョウ ニ カンスル セイネン シンリガク テキ ケンキュウ

Author

ヤン,ヤン, アサカワ,キヨシ, フクイ,シホ, カジワラ,ユキ, ミナミ,マサノリ, Yang,Yang, Asakawa,Kiyoshi, Fukui,Shiho, Kajiwara,Yuki, and Minami,Masanori

Subjects
見捨てられ不安, Anxiety about relationship, psychological adjustment, 心理的適応, school adjustment, 友情の質, 校適応、, Avoidance from intimacy, Adult attachment style, 成人愛必スタイル, 親密性の回避, friendship quality
Published
2013

20. ハッタツ ショウガイジ ニ タイスル タンニン キョウシ ノ タイド ト ジドウ ノ ガッキュウ テキオウカン ノ カンケイ ニカンスル ガッコウ シンリガクテキ ケンキュウ

Author

カジワラ,ユキ, アサカワ,キヨシ, タナカ,ケン, フクイ,シホ, Kajiwara,Yuki, Asakawa,Kiyoshi, Tanaka,Ken, and Fukui,Shiho

Subjects
学級適応感, teachers' attitude, 教師の態度, school adjustment, school psychology, 発達障害, developmental disorders, 学校心理学
Published
2012

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