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237 results on '"Fukai I"'

4. Hysteresis model using distribution of susceptibility

Author

Morita, T., Ishii, Y., and Fukai, I.

Subjects
Magnetic susceptibility -- Distribution, Hysteresis -- Research, Physics
Abstract

The distribution of susceptibility on the M-H plane obtained from the experimental hysteresis loops is used in the preparation of a new hysteresis that reproduces smooth hysteresis curves, including minor loops from several experimental hysteresis loops. The hysteresis loop in the demagnetizing process is found to converge on the original point of the M-H coordinates when computed with this model, and the computed hysteresis curves including minor loops are in agreement with the experimental results.

Published
1993

15. Thymectomy and malignancy

Author

MASAOKA, A, primary, YAMAKAWA, Y, additional, NIWA, H, additional, FUKAI, I, additional, SAITO, Y, additional, TOKUDOME, S, additional, NAKAHARA, K, additional, and FUJII, Y, additional

Published
1994
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27. Histopathologic changes of thymoma preoperatively treated with corticosteroids.

Author

Tateyama, Hisashi, Takahashi, Emiko, Saito, Yushi, Fukai, Ichiro, Fujii, Yoshitaka, Niwa, Hiroshi, Eimoto, Tadaaki, Tateyama, H, Takahashi, E, Saito, Y, Fukai, I, Fujii, Y, Niwa, H, and Eimoto, T

Abstract

Preoperative treatment of thymoma in advanced stages with corticosteroids may reduce the size of the tumor, but no precise histologic evaluation has been performed. We examined the histopathologic features of pretreatment biopsy and posttreatment surgical specimens of eleven cases of thymoma with such treatment to see the changes of the histologic subtypes based on Muller-Hermelink classification. All specimens were also assessed immunohistochemically for MIB-1 labeling and apoptotic cells to verify the effectiveness of this pretreatment. Seven tumors clinically diminished in size after the treatment with corticosteroids. Fungal infection occurred in three cases postoperatively. The histology of mixed thymomas (two cases) was converted to that of medullary thymoma. Predominantly cortical thymomas (four cases) and cortical thymomas (three cases) changed to show similar histologic features; both became epithelial-rich thymoma with large polygonal tumor cells having indistinct cell borders. In contrast, two well-differentiated thymic carcinomas showed at surgery more prominent squamoid appearance with distinct cell borders. The apoptotic indices of epithelial cells were increased (P = 0.001), and the MIB-1 indices tended to be decreased with corticosteroid treatment. These results suggest that there may be a histogenetic relationship between medullary and mixed thymomas and also between predominantly cortical and cortical thymomas. Corticosteroids may cause degenerative changes in the epithelial cells and lymphocytes and, in thymomas in advanced stages, corticosteroid pretreatment may be warranted, although attention should be paid to infection after surgery. [ABSTRACT FROM AUTHOR]

Published
2001
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46. Cten mRNA Expression Is Correlated with Tumor Progression in Thymoma

Author

Sasaki, H., Yukiue, H., Kobayashi, Y., Fukai, I., and Fujii, Y.

Abstract

AbstractCten is a recently isolated gene which has homology with tensin, suggesting that it is a focal adhesion molecule. Tensin family proteins play an important role in cell motility. We attempted to determine the influence of cten expression on clinicopathological features in patients with thymoma who had undergone surgery. Expression of cten messenger RNA was evaluated by reverse-transcription polymerase chain reaction in 45 thymoma samples using a LightCycler. There was no relationship between cten/glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA expression and age, gender or pathological subtypes. However, cten/GAPDH expression was significantly higher in stage IV thymoma (5.463 ± 7.730) when compared to stage I thymoma (0.905 ± 0.811; p = 0.0187). Cten/GAPDH mRNA expression was correlated with evidence of tumor progression in thymoma. Consequently, cell motility or migration might play a role in progression of thymoma.Copyright © 2003 S. Karger AG, Basel

Published
2003

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