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107 results on '"Fujita, Shingo"'

5. Expansion of human alpha‐cell area is associated with a higher maximum body mass index before the onset of type 2 diabetes

Author

Ozawa, Harutoshi, primary, Fukui, Kenji, additional, Fujita, Yukari, additional, Ishibashi, Chisaki, additional, Yoneda, Sho, additional, Nammo, Takao, additional, Fujita, Shingo, additional, Baden, Megu Yamaguchi, additional, Kimura, Takekazu, additional, Tokunaga, Ayumi, additional, Kozawa, Junji, additional, Eguchi, Hidetoshi, additional, and Shimomura, Iichiro, additional

Published
2023
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7. Consumption of two meals per day is associated with increased intrapancreatic fat deposition in patients with type 2 diabetes: a retrospective study

Author

Niki, Akiko, primary, Baden, Megu Y, additional, Kato, Sarasa, additional, Mitsushio, Kento, additional, Horii, Tomomi, additional, Ozawa, Harutoshi, additional, Ishibashi, Chisaki, additional, Fujita, Shingo, additional, Kimura, Takekazu, additional, Fujita, Yukari, additional, Tokunaga, Ayumi, additional, Nammo, Takao, additional, Fukui, Kenji, additional, Kozawa, Junji, additional, and Shimomura, Iichiro, additional

Published
2022
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8. Phenolic Glycosides Citrulluside H and Citrulluside T Isolated From Young Watermelon (Citrullus lanatus) Fruit Have Beneficial Effects Against Cutibacterium acnes -Induced Skin Inflammation.

Author

Itoh, Tomohiro, Muramatsu, Mai, Miyazono, Daiki, Koketsu, Mamoru, Fujita, Shingo, and Hashizume, Toshiharu

Subjects
CUTIBACTERIUM acnes, WATERMELONS, SKIN inflammation, GLYCOSIDES, NITRIC-oxide synthases, REACTIVE oxygen species
Abstract

Acne vulgaris, typically caused by Cutibacterium acnes (C. acnes) involves chronic inflammation of the sebaceous follicles and is the most common skin disease, afflicting 85% of adolescents. We previously isolated 2 novel phenolic glycosides, 2-caffeoyl-3-hydroxy-3-methylbutyric 4′-β-D-glucopyranosyloxy-3′-hydroxybenzyl ester (citrulluside H [CH]) and 2-caffeoyl-3-hydroxy-3-methylbutyric 4′-β- d -glucopyranosyloxybenzyl ester (citrulluside T [CT]), from young fruits of watermelon (Citrullus lanatus). Both compounds suppressed UVB-induced photoaging in human fibroblasts by scavenging intracellular reactive oxygen species (ROS) and thus might be useful as natural skin care ingredients. In this study, we examined the inhibitory effects of these phenolic glycosides on C. acnes growth and C.acnes- induced inflammation. Neither phenolic glycoside inhibited the growth of C. acnes. However, they both significantly suppressed toll-like receptor (TLR) 1/2 or TLR2/6/nuclear factor κB (NF-κB) signaling in heat-killed C. acnes (hk- C. acnes) - stimulated RAW264.7 cells. Additionally, both phenolic glycosides decreased the expression of M1 macrophage biomarkers (cluster of differentiation [ CD ] 80, CD86, and inducible NO synthase [ iNOS ]), suggesting that they attenuate M1 macrophage activation. These results indicated that both CH and CT are potential therapeutic substances against C. acnes -induced skin inflammation. [ABSTRACT FROM AUTHOR]

Published
2023
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11. Genetic assessment using whole-exome sequencing for a young hypertriglyceridemic patient with repeated acute pancreatitis

Author

Fujita, Shingo, primary, Nishizawa, Hitoshi, additional, Miyashita, Yohei, additional, Imada, Tasuku, additional, Yamaguchi, Takashi, additional, Murano, Takeyoshi, additional, Bujo, Hideaki, additional, Asano, Yoshihiro, additional, Kozawa, Junji, additional, Maeda, Norikazu, additional, and Shimomura, Iichiro, additional

Published
2022
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15. Coincidence of Large Adrenal Cyst and Prominent Hyporeninemic Hyperaldosteronism

Author

Sakaue, Takaaki, primary, Okuno, Yosuke, additional, Mukai, Kosuke, additional, Fujita, Shingo, additional, Kozawa, Junji, additional, Nishizawa, Hitoshi, additional, Matsuoka, Taka-Aki, additional, Iwahashi, Hiromi, additional, Norikazu, Maeda, additional, Yamazaki, Yuto, additional, Sasano, Hironobu, additional, Otsuki, Michio, additional, and Shimomura, Iichiro, additional

Published
2021
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18. An Impaired Awareness of Hypoglycemia Improved After Vitamin B12 Treatment in a Type 1 Diabetic Patient

Author

Fujita, Shingo, Kozawa, Junji, Ishibashi, Chisaki, Kimura, Takekazu, Kitamura, Tetsuhiro, Fukui, Kenji, Yasuda, Tetsuyuki, Iwahashi, Hiromi, Imagawa, Akihisa, and Shimomura, Iichiro

Subjects
Male, endocrine system diseases, type 1 diabetes, nutritional and metabolic diseases, Case Report, Vitamin B 12 Deficiency, vitamin B12, Awareness, central nervous system, Hypoglycemia, Diabetes Complications, Vitamin B 12, impaired awareness of hypoglycemia, Humans, Insulin, counter-regulatory hormone, Aged
Abstract

An impaired awareness of hypoglycemia is a serious problem in diabetic patients, which can lead to life-threatening severe hypoglycemia. Recurrent hypoglycemia attenuates the function of the central, mainly hypothalamic, nervous system and it causes an impaired awareness of hypoglycemia. Vitamin B12 deficiency is also associated with the dysfunction of central nervous system. We report a 72-year-old type 1 diabetic patient with vitamin B12 deficiency whose impaired awareness of hypoglycemia improved after 4 weeks of vitamin B12 administration with an increased counter-hormone secretion in response to hypoglycemia. We should recognize vitamin B12 deficiency as one of the causes of an impaired awareness of hypoglycemia in diabetic patients.

Published
2017

25. P‐8: A Novel Bright Reflective Color STN‐LCD with the ISR (Inner Scattering Reflector) Structure

Author

Fujita Shingo, Y. Iwai, T. Hatanaka, Y. Sakurai, Hiroaki Mizuno, and Tetsu Ogawa

Subjects
Physics, Brightness, Optics, Reflector (photography), Liquid-crystal display, business.industry, Scattering, law, Optoelectronics, business, law.invention
Abstract

A novel bright reflective color STN-LCD with the ISR (Inner Scattering Reflector) structure has been developed for the first time in reflective color STN-LCDs. The adoption of the ISR structure enables the LCD to obtain not only clear image without blur but also 2.5 times brightness as high as that of conventional reflective color STN-LCDs.

Published
2000

31. Reflective color STN-LCD technologies

Author

Hisanori Yamaguchi, Tomoaki Sekime, Fujita Shingo, Hiroaki Mizuno, Tetsu Ogawa, Toshiya Ohtani, and Takayuki Hatanaka

Subjects
Liquid-crystal display, Materials science, Color difference, business.industry, SeaChanger Color Engine, Polarizer, law.invention, Gamut, Optics, law, RGB color model, Optoelectronics, Contrast ratio, Optical filter, business
Abstract

Reflective color STN-LCDs should be one of the most promising devices for mobile business tools (MBT), because thedemand such as low cost, low power consumption, light weight and compact size is especially strong for this application. A reflective color STh-LCD with a single polarizer and double retardation films has been investigated. The double retardation films arranged in front of LC-layer enabled the LCD to cotain reflective electrodes inside the panel. Thisconfiguration achieves the bright image with no parallax. A new construction of a reflective STN-LCD with a singlepolarizer has been decided by means of our own method in which the color difference t E* as the optimizing parameterhas been used. Futher, RGB color filters has been newly designed for our reflective LCD, and the aluminum (Al) layer hasbeen introduced as reflective electrodes. As a result, we have realized 7.8-in.-diagonal refrective color STN-LCD(640 x480) which has 15% reflectance, 1 : 14 contrast ratio, 4096 color capability and the sufficient color gamut. It has beenconfirmed that the single polarizer reflective color STh-LCD has sufficient enough performance for MBT use. We believethat it will be a key device for this application.Keywords: reflective color LCD, super twisted nematic (STh), single polarizer mode, electrically controlled birefringence(ECB), retardation film

Published
1998

37. 相補性の哲学的考察

Author

Fujita, Shingo

Subjects
ComputingMethodologies_DOCUMENTANDTEXTPROCESSING
Abstract

1989, 【要旨】

Published
1990

45. Reflective color STN-LCD technologies

Author

Fujita, Shingo, primary, Yamaguchi, Hisanori, additional, Mizuno, Hiroaki, additional, Ohtani, Toshiya, additional, Sekime, Tomoaki, additional, Hatanaka, Takayuki, additional, and Ogawa, Tetsu, additional

Published
1998
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48. A reflective color STN-LCD with a single polarizer and double retardation films

Author

Tomoaki Sekime, Tetsu Ogawa, Fujita Shingo, Hiroaki Mizuno, Takayuki Hatanaka, Toshiya Ohtani, and Hisanori Yamaguchi

Subjects
Liquid-crystal display, Materials science, Birefringence, Color difference, business.industry, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Polarizer, GeneralLiterature_MISCELLANEOUS, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, law.invention, Optics, Gamut, law, Optoelectronics, RGB color model, Contrast ratio, Electrical and Electronic Engineering, business, Parallax, ComputingMethodologies_COMPUTERGRAPHICS
Abstract

— A reflective color STN-LCD with a single polarizer and double retardation films has been investigated. The double retardation films arranged in front of the LC layer enabled the LCD to contain reflective electrodes inside the panel. This configuration achieves a bright image with no parallax. A new construction of a reflective STN-LCD with a single polarizer has been developed by means of our own method in which the color difference ΔE* as the optimizing parameter has been used. Further, RGB color filters have been newly designed for our reflective LCD, and an aluminum (Al) layer has been introduced as a reflective electrode. As a result, we have realized a 7.8-in.-diagonal reflective color STN-LCD (640 × 480) which has 15% reflectance, 14:1 contrast ratio, 4096-color capability, and sufficient color gamut. It has been confirmed that the single-polarizer reflective color STN-LCD has sufficient performance for mobile business tools. We believe that it will be a key device for this application.

Published
1999

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