Search

Your search keyword '"Fujii C"' showing total 356 results
Start Over Author "Fujii C"
356 results on '"Fujii C"'

1. Vacuum-venipuncture skills: time required and importance of tube order

Author

Fujii C

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Chieko FujiiFaculty of Nursing and Medical Care, Keio University, Fujisawa, JapanBackground: The purpose of this study was to assess specific vacuum-venipuncture skills and the influence of the time involved in skin puncture and blood collection.Methods: Thirty subjects undergoing venipuncture in which video analysis was possible were included. These procedures were carried out by four nurses and recorded with a digital camera. Venipuncture skills classified by our observations were delineated on the basis of frame-by-frame video images, and a graph of x and y coordinates was created.Results: With the first blood-collection tube, strong blood flow required the practitioner to push the tube back in to compensate for the strong repulsive force in approximately 46% of cases. By the third blood-collection tube, the blood flow had weakened; therefore, the tube was moved up and down. In cases that required a second venipuncture, the tube was already pierced, so the time required to fill it to 5 mL was significantly longer.Conclusion: Hand movement of the practitioner is adjusted according to blood flow. Reflex movement in response to strong blood flow may increase the risk of pushing the needle through the vein with excessive force. The time required to fill the tube varies among nurses, tube order, and level of venipuncture skills.Keywords: blood collection, blood-collection tube, clinical practice, venipuncture skill

Published
2013

2. Clarification of the characteristics of needle-tip movement during vacuum venipuncture to improve safety

Author

Fujii C

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Chieko FujiiFaculty of Nursing and Medical Care, Keio University, Kanagawa, JapanBackground: Complications resulting from venipuncture include vein and nerve damage, hematoma, and neuropathic pain. Although the basic procedures are understood, few analyses of actual data exist. It is important to improve the safety standards of this technique during venipuncture. This study aimed to obtain data on actual needle movement during vacuum venipuncture in order to develop appropriate educational procedures.Methods: Six experienced nurses were recruited to collect blood samples from 64 subjects. These procedures were recorded using a digital camera. Software was then used to track and analyze motion without the use of a marker in order to maintain the sterility of the needle. Movement along the X- and Y-axes during blood sampling was examined.Results: Approximately 2.5 cm of the needle was inserted into the body, of which 6 mm resulted from advancing or moving the needle following puncture. The mean calculated puncture angle was 15.2°. Given the hazards posed by attaching and removing the blood collection tube, as well as by manipulating the needle to fix its position, the needle became unstable whether it was fixed or not fixed.Conclusion: This study examined venipuncture procedures and showed that the method was influenced by increased needle movement. Focusing on skills for puncturing the skin, inserting the needle into the vein, and changing hands while being conscious of needle-tip stability may be essential for improving the safety of venipuncture.Keywords: blood collection, nerve damage, motion analysis, patient safety, puncture angle, clinical education

Published
2013

4. Responding to experienced and anticipated discrimination (READ): Anti -stigma training for medical students towards patients with mental illness - Study protocol for an international multisite non-randomised controlled study

Author

Deb T., Lempp H., Bakolis I., Vince T., Waugh W., Henderson C., Thornicroft G., Ando S., Yamaguchi S., Matsunaga A., Kondo S., Ichihashi K., Ojio Y., Ogawa M., Fujii C., Kasai K., Candelas A., Martin L., Jimenez A., Castaneda C., Hernandez C., De La Higuera J., Munoz-Negro J. E., Sola M., Garcia R., Gota J. M., Mula J. F., Lopez A., Oria A., Cervilla J. A., Bono A., Franco D., Gomez J., Jimenez C., Dorado R., Ingunza E., Marquez I., De La Vega D., Go-Cubillana P., Ouali U., Jouini L., Zgueb Y., Jomli R., Nacef F., Campbell M., Stein D., Harangozo J., Ojo T. M., Ogunwale A., Sowunmi A. O., Awhangansi S. S., Ogundapo D., Sodiya O. T., Fadipe B., Olagunju A. T., Erinfolami A. R., Ogunnubi P. O., Tomas C. C., Krupchanka D., Pascucci M., Bacle S. V., Colliez A., Sebbane D., Mengin A., Vidailhet P., Cazals C., Ucok A., Fiorillo A., Sampogna G., Savorani M., Del Vecchio V., Luciano M., Borriello G., Pocai B., Nwaubani P., James Y., Tocca A., Pattnaik R., Chilasagaram S., Wufang Z., Deb, T., Lempp, H., Bakolis, I., Vince, T., Waugh, W., Henderson, C., Thornicroft, G., Ando, S., Yamaguchi, S., Matsunaga, A., Kondo, S., Ichihashi, K., Ojio, Y., Ogawa, M., Fujii, C., Kasai, K., Candelas, A., Martin, L., Jimenez, A., Castaneda, C., Hernandez, C., De La Higuera, J., Munoz-Negro, J. E., Sola, M., Garcia, R., Gota, J. M., Mula, J. F., Lopez, A., Oria, A., Cervilla, J. A., Bono, A., Franco, D., Gomez, J., Jimenez, C., Dorado, R., Ingunza, E., Marquez, I., De La Vega, D., Go-Cubillana, P., Ouali, U., Jouini, L., Zgueb, Y., Jomli, R., Nacef, F., Campbell, M., Stein, D., Harangozo, J., Ojo, T. M., Ogunwale, A., Sowunmi, A. O., Awhangansi, S. S., Ogundapo, D., Sodiya, O. T., Fadipe, B., Olagunju, A. T., Erinfolami, A. R., Ogunnubi, P. O., Tomas, C. C., Krupchanka, D., Pascucci, M., Bacle, S. V., Colliez, A., Sebbane, D., Mengin, A., Vidailhet, P., Cazals, C., Ucok, A., Fiorillo, A., Sampogna, G., Savorani, M., Del Vecchio, V., Luciano, M., Borriello, G., Pocai, B., Nwaubani, P., James, Y., Tocca, A., Pattnaik, R., Chilasagaram, S., and Wufang, Z.

Subjects
Internationality, Students, Medical, Social Stigma, lcsh:Medicine, Social Sciences, INDIGO READ study group, Study Protocol, Statistical analyses, Discrimination, REDUCE PREJUDICE, SCALE, Schools, Medical, lcsh:LC8-6691, Mental Disorders, EDUCATION, General Medicine, Social Discrimination, Distress, HOSPITAL-CARE, Research Design, Mental Disorder, Psychology, INTERVENTIONS, Human, Education, Medical, Undergraduate, Medical education, medicine.medical_specialty, Evidence-based practice, Attitude of Health Personnel, 1302 Curriculum and Pedagogy, education, Developing country, EMPATHY, 1117 Public Health and Health Services, HEALTH-RELATED STIGMA, INTERGROUP CONTACT, PEOPLE, medicine, Humans, Education, Scientific Disciplines, Health professionals, lcsh:Special aspects of education, Public health, lcsh:R, Mental illness, medicine.disease, Education & Educational Research, Stigma, DEPRESSIVE DISORDER, Medical Informatics
Abstract

BackgroundStigma and discrimination are a significant public health concern and cause great distress to people with mental illness. Healthcare professionals have been identified as one source of this discrimination. In this article we describe the protocol of an international, multisite controlled study, evaluating the effectiveness of READ, an anti-stigma training for medical students towards patients with mental illness. READ aims to improve students’ ability to minimise perceived discriminatory behaviours and increase opportunities for patients, therefore developing the ability of future doctors to address and challenge mental illness related discrimination. READ includes components that medical education research has shown to be effective at improving attitudes, beliefs and understanding.Methods/designREAD training was developed using evidence based components associated with changes in stigma related outcomes. The study will take place in multiple international medical schools across high, middle and low income countries forming part of the INDIGO group network, with 25 sites in total. Students will be invited to participate via email from the lead researcher at each site during their psychiatry placement, and will be allocated to an intervention or a control arm according to their local teaching group at each site. READ training will be delivered solely to the intervention arm. Standardised measures will be used to assess students’ knowledge, attitudes and skills regarding discrimination in both the intervention and control groups, at baseline and at follow up immediately after the intervention. Statistical analyses of individual-level data will be conducted using random effects models accounting for clustering within sites to investigate changes in mean or percentages of each outcome, at baseline and immediately after the intervention.DiscussionThis is the first international study across high, middle and low income countries, which will evaluate the effectiveness of training for medical students to respond effectively to patients’ experiences and anticipation of discrimination. The results will promote implementation of manualised training that will help future doctors to reduce the impact of mental illness related discrimination on their patients. Limitations of the study are also discussed.

Published
2019

6. The effects of make up on ADL of female patients in the psychiatric closed ward

Author

Shibata, S, Yamamoto, A, Teranishi, Y, Fujii, C, Nagahama, K, and Murata, M

Subjects
female, makeup, 閉鎖病棟, 化粧, Schizophrenia, 統合失調症, 女性, closed ward, psychiatry, 精神科
Abstract

多くの女性にとって化粧は,精神的満足や自尊感情を高めるための重要な行為だといわれるが,入院が長期化しがちな精神科病院においては,社会生活から遠ざかる中で,化粧に対する関心や欲求そのものが希薄になり,それがまた,医療者側の化粧への配慮を失わせて行くという負の循環を生み出してきた.しかしながら,化粧には,陰性症状,協調性,自発性等の改善効果があることや,「自・他の関心」や「女性としての生き方を考える」などの変化をもたらすという報告がある.そこで本研究では,統合失調症により精神科閉鎖病棟に入院する女性10名(希望者)を対象に化粧会を実施し,化粧による日常生活行動(ADL:activity of daily living)への影響について検討した.その結果,化粧は,ADL評価点を向上させ,さらにその効果は化粧会実施後も持続することが認められた.化粧には統合失調症を持つ女性の現実感覚を回復させ,ADLを改善する効果のあることが示唆された.(著者抄録)

Published
2014

9. Excess mortality in persons with severe mental disorders: a multilevel intervention framework and priorities for clinical practice, policy and research agendas

Author

Liu , N.H., Daumit , G.L., Dua , T., Aquila , R., Charlson , F., Cuijpers, Pim, Druss , B., Dudek , K., Freeman , M., Fujii , C., Gaebel , W., Hegerl , U, Levav , I., Laursen , T.M., Ma , H., Maj , M., Medina-Mora , M.E., Nordentoft , M., Prabhakaran , D., Pratt , K., Prince , M., Rangaswamy , T., Shiers , D., Susser , E., Thornicroft , G., Wahlbeck , K., Wassie , A.F., Whitefield , H., Saxena , S., Liu , N.H., Daumit , G.L., Dua , T., Aquila , R., Charlson , F., Cuijpers, Pim, Druss , B., Dudek , K., Freeman , M., Fujii , C., Gaebel , W., Hegerl , U, Levav , I., Laursen , T.M., Ma , H., Maj , M., Medina-Mora , M.E., Nordentoft , M., Prabhakaran , D., Pratt , K., Prince , M., Rangaswamy , T., Shiers , D., Susser , E., Thornicroft , G., Wahlbeck , K., Wassie , A.F., Whitefield , H., and Saxena , S.

Abstract

Excess mortality in persons with severe mental disorders (SMD) is a major public health challenge that warrants action. The number and scope of truly tested interventions in this area remain limited, and strategies for implementation and scaling up of programmes with a strong evidence base are scarce. Furthermore, the majority of available interventions focus on a single or an otherwise limited number of risk factors. Here we present a multilevel model highlighting risk factors for excess mortality in persons with SMD at the individual, health system and socio-environmental levels. Informed by that model, we describe a comprehensive framework that may be useful for designing, implementing and evaluating interventions and programmes to reduce excess mortality in persons with SMD. This framework includes individual-focused, health system-focused, and community level and policy-focused interventions. Incorporating lessons learned from the multilevel model of risk and the comprehensive intervention framework, we identify priorities for clinical practice, policy and research agendas.

Published
2017
Full Text
View/download PDF

16. DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway

Author

Alexaki, V I, primary, Fodelianaki, G, additional, Neuwirth, A, additional, Mund, C, additional, Kourgiantaki, A, additional, Ieronimaki, E, additional, Lyroni, K, additional, Troullinaki, M, additional, Fujii, C, additional, Kanczkowski, W, additional, Ziogas, A, additional, Peitzsch, M, additional, Grossklaus, S, additional, Sönnichsen, B, additional, Gravanis, A, additional, Bornstein, S R, additional, Charalampopoulos, I, additional, Tsatsanis, C, additional, and Chavakis, T, additional

Published
2017
Full Text
View/download PDF

20. DHEA inhibits acute microglia-mediated inflammation through activation of the TrkA-Akt1/2-CREB-Jmjd3 pathway

Author

Alexaki, V I, Fodelianaki, G, Neuwirth, A, Mund, C, Kourgiantaki, A, Ieronimaki, E, Lyroni, K, Troullinaki, M, Fujii, C, Kanczkowski, W, Ziogas, A, Peitzsch, M, Grossklaus, S, Sönnichsen, B, Gravanis, A, Bornstein, S R, Charalampopoulos, I, Tsatsanis, C, and Chavakis, T

Abstract

Dehydroepiandrosterone (DHEA) is the most abundant circulating steroid hormone in humans, produced by the adrenals, the gonads and the brain. DHEA was previously shown to bind to the nerve growth factor receptor, tropomyosin-related kinase A (TrkA), and to thereby exert neuroprotective effects. Here we show that DHEA reduces microglia-mediated inflammation in an acute lipopolysaccharide-induced neuro-inflammation model in mice and in cultured microglia in vitro. DHEA regulates microglial inflammatory responses through phosphorylation of TrkA and subsequent activation of a pathway involving Akt1/Akt2 and cAMP response element-binding protein. The latter induces the expression of the histone 3 lysine 27 (H3K27) demethylase Jumonji d3 (Jmjd3), which thereby controls the expression of inflammation-related genes and microglial polarization. Together, our data indicate that DHEA-activated TrkA signaling is a potent regulator of microglia-mediated inflammation in a Jmjd3-dependent manner, thereby providing the platform for potential future therapeutic interventions in neuro-inflammatory pathologies.

Published
2018
Full Text
View/download PDF

22. Deacetylation as a determinant of sulphonamide pharmacokinetics in pigs

Author

Fujii C, Son Ds, Minoru Shimoda, Sikazwe G, and Okamoto K

Subjects
Sulfonamides, Chromatography, Time Factors, General Veterinary, Sulfamonomethoxine, Swine, Metabolite, Area under the curve, Sulfadiazine, Acetylation, Sulfamethazine, Urine, Models, Biological, chemistry.chemical_compound, Reaction rate constant, chemistry, Pharmacokinetics, Anti-Infective Agents, Renal physiology, Area Under Curve, Injections, Intravenous, Animals, Swine, Miniature, A determinant
Abstract

Sulphamonomethoxine (SMM), sulphadimidine (SDD), sulphadiazine (SDZ) and their N4-acetyl derivatives (AcSMM, AcSDD and AcSDZ) were intravenously injected into Goettingen miniature pigs and deacetylation was evaluated from plasma concentration-time curves, renal excretion, and rate constants obtained from pharmacokinetic analysis, using a non-linear least-squares method. Deacetylated metabolite was detected in both plasma and urine after intravenous injection of AcSMM, AcSDD and AcSDZ. The area under the curve (AUC) values for the deacetylated metabolite were significantly higher than those for acetyl derivatives after AcSMM and AcSDD administration, but significantly lower after AcSDZ. After AcSMM and AcSDD injection, the concentration ratio between deacetylated metabolite and acetyl derivative was almost constant in the terminal linear phase and similar to that seen after injection of sulphonamide. After AcSDZ injection, however, a constant ratio was not observed. These results indicate that deacetylation can have a significant effect on the pharmacokinetics of SMM and SDD, but not on those of SDZ in pigs. The rate constant for deacetylation was significantly higher than that for acetylation for SMM and SDD, but significantly lower for SDZ. It is, therefore, concluded that deacetylation may be a determinant of the pharmacokinetics of SMM and SDD in pigs. It was, however, not a determinant of SDZ pharmacokinetics because N4-acetylation is not the main elimination route in pigs.

Published
1997

25. Multicenter phase II study of a frozen glove to prevent docetaxel-induced onycholysis and cutaneous toxicity for the breast cancer patients (Kinki Multidisciplinary Breast Oncology Group: KMBOG-0605).

Author

Sakurai, M, primary, Todaka, K, additional, Takada, N, additional, Kamigaki, S, additional, Anami, S, additional, Shikata, A, additional, Ueno, H, additional, Iseki, C, additional, Fujii, C, additional, Fujino, M, additional, Yamamura, J, additional, Masuda, H, additional, Ishitobi, M, additional, Nakayama, T, additional, and Masuda, N, additional

Published
2009
Full Text
View/download PDF

43. Effects Of Combinations Of Patternmaking Methods And Dress Forms On Garment Appearance

Author

Fujii Chinami, Takatera Masayuki, and Kim KyoungOk

Subjects
basic pattern, appearance, sensory evaluation, Textile bleaching, dyeing, printing, etc., TP890-933
Abstract

We investigated the effects of the combinations of patternmaking methods and dress forms on the appearance of a garment. Six upper garments were made using three patternmaking methods used in France, Italy, and Japan, and two dress forms made in Japan and France. The patterns and the appearances of the garments were compared using geometrical measurements. Sensory evaluations of the differences in garment appearance and fit on each dress form were also carried out. In the patterns, the positions of bust and waist darts were different. The waist dart length, bust dart length, and positions of the bust top were different depending on the patternmaking method, even when the same dress form was used. This was a result of differences in the measurements used and the calculation methods employed for other dimensions. This was because the ideal body shape was different for each patternmaking method. Even for garments produced for the same dress form, the appearances of the shoulder, bust, and waist from the front, side, and back views were different depending on the patternmaking method. As a result of the sensory evaluation, it was also found that the bust and waist shapes of the garments were different depending on the combination of patternmaking method and dress form. Therefore, to obtain a garment with better appearance, it is necessary to understand the effects of the combinations of patternmaking methods and body shapes.

Published
2017
Full Text
View/download PDF

45. The Lectin Concanavalin A Stimulates a Protein-Tyrosine Kinase p72syk in Peripheral Blood Lymphocytes

Author

Takeuchi, F., Taniguchi, T., Maeda, H., Fujii, C., Takeuchi, N., and Yamamura, H.

Abstract

We report that the activation of porcine peripheral blood lymphocytes (PBL) by ectin concanavalin A (Con A) led to the increase in tyrosine phosphorylation on 84-, 72-, 55-, 40-, and 33-kDa proteins. A non-receptor protein-tyrosine kinase (PTK), p72syk (Taniguchi et al. (1991) J. Biol. Chem. 266, 15790-15796), was detected in PBL around 0.1 % of total protein and distributed in both particulate and cytosolic fractions. Furthermore, Con A induced a rapid activation of p72syk within 1 min in a manner similar to the time course of Con A-induced protein-tyrosine phosphorylation. These results suggest that p72syk plays a certain role in the activation of PBL and that p72syk may be one of the major non-receptor PTKs in T cells as well as in B cells.Copyright 1993, 1999 Academic Press

Published
1993
Full Text
View/download PDF

47. Solution Chemistry in Crevices on Fe-Cr Binary Alloys

Author

NAVAL RESEARCH LAB WASHINGTON DC, Bogar, F. D., Fujii, C. T., NAVAL RESEARCH LAB WASHINGTON DC, Bogar, F. D., and Fujii, C. T.

Abstract

The major cation concentrations and pH's were measured in crevices on Fe-Cr alloys under potentiostatic conditions in the laboratory and on larger commercial steel specimens freely corroding in natural seawater. Crevice solutions were analyzed by thin-layer chromatography. The ratio of the cations in the crevice solutions was not equal to the ratio of the metals in the alloys; the ionic concentrations in the crevice solutions were determined, to a very large extent, by transport phenomena between the crevice and bulk solutions.

Published
1974

48. The SCC Properties of Modified High-Strength Steel Plates and Weld Metals.

Author

NAVAL RESEARCH LAB WASHINGTON DC, Fujii,C T, NAVAL RESEARCH LAB WASHINGTON DC, and Fujii,C T

Abstract

This report describes the results of baseline studies on the effects of chemical, metallurgical, and mechanical factors on the SCC properties of high-strength steels and weldments. The primary materials were quench-and-tempered steels or weld metals in the HY-100 and HY-130 systems with complex martensitic microstructures. The cantilever beam method was used to measure K sub Iscc of the materials in 3.5% sodium chloride (NaCl) solution under zinc-coupled conditions. This parameter was utilized to rank the materials and to evaluate the effects of processing, welding procedure, and tempering on SCC properties. (Author)

Published
1979

49. Stress-Corrosion-Cracking Characterization of High-Strength Steels-Base Metals and Weldments.

Author

NAVAL RESEARCH LAB WASHINGTON D C, Fujii,C T, Fraser,F W, Metzbower,E A, NAVAL RESEARCH LAB WASHINGTON D C, Fujii,C T, Fraser,F W, and Metzbower,E A

Abstract

This report describes the results of studies on the effects of compositional, metallurigical, and microstructural factors on the SCC behavior of high-strength steels and weldments. The primary materials were quench-and-tempered steels or weldments in the HY-130 and HY-180 systems with complex martensitic microstructures. The cantilever beam method was used to establish the materials' SCC characteristics. These characteristics, complemented by fractographic and metallorgraphic examinations, identified potential pathways for improving weldment properties. The influence of processing, welding, and heat treating on microstructures, and correlations of the latter with SCC behavior and fracture modes, were examined. (Author)

Published
1978

50. Effect of Specimen Dimensions of K sub Iscc Determination by the Cantilever Method.

Author

NAVAL RESEARCH LAB WASHINGTON D C, Fujii,C T, NAVAL RESEARCH LAB WASHINGTON D C, and Fujii,C T

Abstract

There is a critical need for standardization of K sub Iscc test procedures to assure the documentation of only valid data. An important area of concern is the development of realistic specimen requirements which are applicable to K sub Iscc tests rather than adopting those used in K sub IC determinations. The present studies were aimed at systematically evaluating the effects of specimen thickness, ligament length, and initial crack length on the threshold for stress-corrosion crack growth K sub ISCC by the cantilever method.

Published
1978

Catalog

Books, media, physical & digital resources
See catalog results