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Reef-building coral species of the order Scleractinia play an important role in shallow tropical seas by providing an environmental base for the ecosystem. The molecular data of complete mitochondrial genome have become an important source for evaluating phylogenetic and evolutionary studies of Scleractinia. Here, the complete mitogenome of Homophyllia bowerbanki (Milne Edwards and Haime, 1857), collected from Nansha Islands of the South China Sea, was sequenced for the first time through a next-generation sequencing method. H. bowerbanki is the first species of its genus for which the mitogenome was sequenced. This mitogenome was 18,154 bp in size and included two transfer RNA genes (tRNAs), 13 protein-coding genes (PCGs), and two ribosomal RNA genes (rRNAs). It showed a similar gene structure and gene order to the other typical scleractinians. All 17 genes were encoded on the H strand and the total GC content was 33.86% in mitogenome. Phylogenetic analysis (maximum likelihood tree method) showed that H. bowerbanki belonged to the “Robust” clade and clustered together with other two species in the family Lobophylliidae based on 13 PCGs. The mitogenome can provide significant molecular information to clarify the evolutionary and phylogenetic relationships between stony corals and to facilitate their taxonomic classification; it can also support coral species monitoring and conservation efforts.

Purpose Renal artery stenosis leads to ischemic renal insufficiency, but methods for assessing renal perfusion are limited. This study aimed to evaluate the association between renal slow perfusion and impaired renal function in atherosclerotic renal artery stenosis (ARAS). Patients and Methods A total of 79 consecutive patients with uncontrolled hypertension who underwent renal angiography and renal dynamic scintigraphy for suspected ARAS were enrolled in the retrospective descriptive study. Based on the status of renal artery stenosis and renal perfusion, participants were divided into three groups: the control group (n=26), the unilateral ARAS with renal normal perfusion group (RNP, n=30), and the unilateral ARAS with renal slow perfusion group (RSP, n=23). RSP was defined as renal blush grade (RBG) ≤1, while RBG>1 belonged to RNP. Split renal function (SRF) was achieved from 99mTc-DTPA renal scintigraphy. The value of the difference in split renal function (DSRF) is contralateral SRF minus impaired SRF of paired kidneys in ARAS. We compared the SRF and DSRF between different groups to identify the association between renal slow perfusion and renal impairment in ARAS. Results We analyzed SRF for paired kidneys and found the following: (1) The SRF of the paired kidney was similar in the RNP group (24.3 ± 10.2 mL/min vs 27.5 ± 8.4 mL/min; P = 0.19); however, the impaired SRF was obviously decreased compared with the contralateral SRF in the RSP group (13.5 ± 8.6 mL/min vs 36.7 ± 16.9 mL/min; P < 0.001); and (2) The difference in SRF in the RSP group was significantly higher than that in the control and RNP groups (19.8 ± 11.9 mL/min vs 4.8 ± 8.1 mL/min; 19.8 ± 11.9 mL/min vs 4.6±3.7 mL/min; P < 0.05). Conclusion As an angiographic phenomenon, renal slow perfusion might be an indicator of severely impaired renal function.

Downward continuation is known as one of the crucial steps in interpreting gravity or magnetic data. As the continuation depth and the influence of noise increases, the results of downward continuation become unstable. Based on the computation of the Chebyshev-Pade approximation function obtained by the Tikhonov regularization, this paper proposes a new regularized method intended for the downward continuation of potential fields. The Chebyshev-Pade approximation function is applied to calculate the continuation factor. In this study, the cross-correlation method is adopted to calculate the cut-off wavenumber, while the regularized low-pass filter is designed to calculate the downward continuation of the potential field. In order to validate this method, numerical simulation is conducted. We calculate the root mean square error of the theoretical data on the target plane and the data of downward continuation, as obtained using the improved regularization operator method, the Chebyshev-Pade approximation function method, the regularized Chebyshev-Pade approximation function method, and the method proposed in this paper, based on which a comparison is conducted. According to the simulation and experimental results, the effects of the continuation depth can be reduced significantly by the proposed method. Besides, the method demonstrates strong resistance to noise.

Background Delayed coronary artery occlusion (CAO) is a rare but fatal complication after transcatheter aortic valve replacement, chimney stenting is the standard technique for established CAO or impending CAO. Case presentation We describe a female patient who developed non-ST elevation myocardial infarction after receiving transcatheter aortic valve replacement and chimney stenting 4 months prior. An angiogram revealed delayed coronary artery occlusion with a deformed stent, which was never reported. This patient was subsequently treated with a new chimney stent. Conclusions For self-expanding valves, the coronary ostium is protected by chimney stenting, delayed coronary artery occlusion can occur and cause catastrophic complications.

In this paper, a new method for fault detection of parallel shaft gearbox based on the Empirical Mode Decomposition (EMD) and Multipoint Optimal Minimum Entropy Deconvolution (MOMEDA) is proposed. MOMEDA can overcome the shortcomings of minimum entropy deconvolution (MED) and Maximum Correlated Kurtosis Deconvolution (MCKD), and it is introduced to extract the fault cycle of gearbox signals. The vibration signals of gearbox are complex, including fault signals, noise signals and deterministic signals such as gear meshing component. Fault signal is often buried in these other components, which increases the difficulty of gearbox fault detection. Thus the EMD is proposed to decompose the signal and extract the fault impact components from the signal. The parallel shaft gearbox preset fault experiment is carried out to verify the effectiveness of method. In addition, some traditional methods, such as Fourier transform, cepstrum analysis, MED and MCKD, are used to compare with the proposed methods. Experimental results show that the effectiveness of the proposed method is better than that of traditional methods.

Gearbox compound fault pattern recognition is challenging because of its complexity and non-stationarity of the vibration signal. In this study is proposed a novel hybrid method based on narrow band interference canceller (NIC), multifractal detrended fluctuation analysis (MFDFA) and support vector machine optimized by whale optimization algorithm (WOASVM) for compound fault pattern recognition of gearbox. Specifically, the raw signal is processed by NIC to filter the deterministic signal which interferes with the fault signal, and then the multifractal features are extracted from the residual signal via MFDFA. Finally, the compound fault pattern is identified via WOASVM. Compound fault experiments of a gearbox under fixed condition and variable condition were done to evaluate the performance of the proposed method. The results show that the proposed method can effectively identify the compound faults and it outperforms other methods mentioned in this paper.

Melting is a common solidification treatment that concentrates and encapsulates heavy metals into a glass matrix for waste containing heavy metals (Chae et al., 2016). To control the risk of heavy metal leaching into the glass product, a reduction in the amount of heavy metal was achieved in a pilot-scale furnace by co-melting electroplating sludge (EPS) and municipal solid waste incineration fly ash (MSWI FA). Through the melting process, the chloride from MSWI FA led to heavy metals volatilization in the form of chlorine salts. The fly ash additionally increased heavy metals volatilization by 4%–91%. The highest volatilization ratios of Zn, Pb, Cu, Cd, Cr and Ni were 33%, 96%, 33%, 79%, 81% and 31%, respectively. The concentrations of Pb and Zn in the secondary fly ash were close to the Pb and Zn concentrations in lead-zinc ore that are required in smelting industry. Moreover, glass sand was produced after the melting treatment. With an increase in the fly ash mixing ratio, the leaching concentration of Zn and Cu decreased to 3.8 mg/L and 2.1 mg/L. The leaching concentrations of other heavy metals stayed below 1 mg/L in all cases. When the ratio of MSWI FA reached 10%, the glass sand contained the least amount of impurities and a large amount of phosphate and silicate, which were probably responsible for the stability of the heavy metals. Therefore, our results provided a promising approach to the stability of the waste by the recovery of heavy metals in the co-treatment of heavy metal-bearing wastes.

Background: Coronary angiography-derived fractional flow reserve (caFFR) measurements have shown good correlations and agreement with invasive wire-based fractional flow reserve (FFR) measurements. However, few studies have examined the diagnostic performance of caFFR measurements before and after percutaneous coronary intervention (PCI). This study sought to compare the diagnostic performance of caFFR measurements against wire-based FFR measurements in patients before and after PCI.Methods: Patients who underwent FFR-guided PCI were eligible for the acquisition of caFFR measurements. Offline caFFR measurements were performed by blinded hospital operators in a core laboratory. The primary endpoint was the vessel-oriented composite endpoint (VOCE), defined as a composite of vessel-related cardiovascular death, vessel-related myocardial infarction, and target vessel revascularization.Results: A total of 105 pre-PCI caFFR measurements and 65 post-PCI caFFR measurements were compared against available wire-based FFR measurements. A strong linear correlation was found between wire-based FFR and caFFR measurements (r = 0.77; p < 0.001) before PCI, and caFFR measurements also showed a high correlation (r = 0.82; p < 0.001) with wire-based FFR measurements after PCI. A total of 6 VOCEs were observed in 61 patients during follow-up. Post-PCI FFR values (≤0.82) in the target vessel was the strongest predictor of VOCE [hazard ratio (HR): 5.59; 95% confidence interval (CI): 1.12–27.96; p = 0.036). Similarly, patients with low post-PCI caFFR values (≤0.83) showed an 8-fold higher risk of VOCE than those with high post-PCI caFFR values (>0.83; HR: 8.83; 95% CI: 1.46–53.44; p = 0.017).Conclusion: The study showed that the caFFR measurements were well-correlated and in agreement with invasive wire-based FFR measurements before and after PCI. Similar to wire-based FFR measurements, post-PCI caFFR measurements can be used to identify patients with a higher risk for adverse events associated with PCI.

Aims: The EVOLVE China randomised study sought to evaluate the clinical safety and effectiveness of the SYNERGY bioabsorbable polymer-coated everolimus-eluting stent (EES) for the treatment of patients with coronary heart disease in China. Methods and results: Eligible patients with de novo native coronary artery lesions were randomised (1: 1) to receive the SYNERGY or PROMUS Element Plus stent. The primary endpoint was in-stent late loss at nine months. Secondary endpoints included death, MI, revascularisation, and stent thrombosis up to 12 months. A total of 412 subjects were randomised (205 SYNERGY; 207 PROMUS Element Plus) at 14 sites in China from October 2013 to July 2014. SYNERGY was non-inferior to PROMUS Element Plus for the primary endpoint of nine-month in-stent late loss: SYNERGY 0.20 +/- 0.33 mm vs. PROMUS Element Plus 0.17 +/- 0.38 mm with an upper one-sided 97.5% confidence interval of the difference (0.10 mm), significantly less than the non-inferiority margin (0.15 mm; pl0.0008). Clinical adverse event rates were low and not significantly different between groups at nine and 12 months (all pg0.05). Conclusions: In the EVOLVE China trial, the SYNERGY bioabsorbable polymer-coated EES was noninferior to the PROMUS Element Plus permanent polymer-coated EES for the primary endpoint of late loss at nine months.

This paper addresses a new method of fault diagnosis for parallel shaft gearbox. Aiming at the nonlinear and non-stationary characteristics of gearbox vibration signals, the Multifractal Detrended Fluctuation Analysis (MFDFA) is introduced to calculate the multifractal spectrum parameters as fault features, and combined with the improved K means clustering to detect the failure of gearbox. The above methods are verified through using the fault data of gearbox preposition failure experiment, and the result shows that the methods have good effect.

In the current work, a quick prediction of the heavy metal (HM) leaching potential in municipal solid waste incineration fly ash (MSWI FA) was developed based on the statistical data between the HM leaching behaviors and the compositional variety in FA from China. In the comparison of the surveyed (508 data points) leaching concentrations, Pb and Cd leaching amounts in FA exceeded the Toxicity Characteristic Leaching Procedure (TCLP) limits most frequently. Moreover, the chemical compositions (pH and soluble chlorine (S-Cl)) of FA were proposed to have significant linear correlations with the Pb and Cd leaching. This corresponded to the chemical fraction change of the HM (risk assessment code (RAC)), which was relative to the pH of FA and chloride. This suggests that the HM stability can be evaluated by these factors. To verify this hypothesis, principal component analysis (PCA) and multiple linear regressions were used to evaluate the relationship between 5 indices and the leaching concentrations of Pb and Cd in 160 MSWI FA samples after stabilization/solidification from eastern China. It is indicated that pH, S-Cl and free CaO were the critical variables in Pb and Cd leaching. Accordingly, a new index, Φ, combined with the logistic model was proposed to predict the leaching potential. It is revealed that the high risk of the exceeding the limits for HM leaching occurred when Φ was below 12.5. Our results assess the HM stability in MSWI FA with its compositional variety in a statistical way, which gives an approach for the quick prediction of HM leaching potential.

Patient Initials or Identifier Number WJW ### Relevant Clinical History and Physical Exam A 60 years old male patient was admitted with a chest tightness for one year and aggravation for one month. His coronary risk factor included hypertension, hyperlipidemia, and smoking for 40 years. He

The rolling bearings are one of the most critical and prevalent elements in rotating machinery. It is necessary to develop a suitable health assessment method to prevent malfunctions and breakages during operation. In this paper, a novel health assessment method for bearings based on Hilbert transform envelope analysis and cluster analysis is proposed. The high-pass filter and Hilbert transform envelope analysis are used to enable the original signal to become smooth and gentle, so as to reduce the influence of noise. And the combination of time domain features parameters is chosen to evaluate the bearing health state. Then extracted feature parameters are clustered by using improved K-means algorithm. In this paper, bearing degradation data and fault data are used to prove the effectiveness of the method.

State-space model is often used to estimate system degradation. However, the state-space model is usually only one observation equation in existing research, and it only applies to one observation indicator. This paper puts forward an adaptive state-space model, which can be applied to multiple observation indicators. The modeling method and parameter estimation approach of adaptive state-space model are studied. In order to show that the proposed model is better than traditional state-space model, planetary gearbox remaining useful life (RUL) estimation based on adaptive state-space model is carried out.

Patient initials or identifier number yq ### Relevant clinical history and physical exam A 70-year old patient was admitted to our hospital for 3 years effort angina. He underwent angiography 2 months ago which showed very severe coronary diseases, he refused CABG and took medicine treatment

Advanced oxidation processes (AOPs) for degrading disperse dyes were developed to utilize nano-iron modified goldmine waste-solid as the heterogeneous catalyst for a Fenton-like oxidation. The removal performance of Dispersed Orange 288 effluent was investigated by homogeneous catalyzed Fenton reactions as well as heterogeneous adsorption for raw and modified goldmine waste-solid. And maximal DOC removal is 32.3% when 9 g modified goldmine waste-solid was added in 100 ml solution in heterogeneous adsorption process. While in the nanoiron modified goldmine waste-solid assisted AOPs, it is found that combination of adsorption treatment and advanced oxidation processes exhibits the stronger degradation capacity. By varying concentration of H2O2 from 10 to 50 ml/L, the COD removal of Dispersed Orange 288 effluent under 3 g modified goldmine waste-solid was observed being increased from 20.3 to 68.6%.

We evaluated the efficacy of β-radiation therapy (188Re-MAG3) to inhibit intimal hyperplasia (IH) in diffuse in-stent restenosis by intravascular ultrasound (IVUS) analysis in 50 patients. Nine patients who did not agree with radiation therapy, and therefore underwent rotational atherectomy and balloon angioplasty for diffuse in-stent restenosis in the same study period, were selected for control groups. Serial IVUS comparisons were available in 44 of 50 patients with radiation therapy and 7 of 9 control patients. At 6-month follow-up, there was less significant increase of IH area in patients with radiation therapy than in control patients (Δ IH area = 0.1 ± 0.8 mm2 vs. 2.6 ± 1.8 mm2, P > 0.001 in mean values, and 0.6 ± 1.4 mm2 vs. 2.9 ± 2.1 mm2, P = 0.026 in values of follow-up lesion site, respectively). In conclusion, β-radiation therapy might be an effective treatment modality to inhibit intimal hyperplasia in patients with diffuse in-stent restenosis. Cathet Cardiovasc Intervent 2001;54:169–173. © 2001 Wiley-Liss, Inc.

Increased T-wave amplitude is one of the earliest electrocardiographic (ECG) changes following coronary artery occlusion. Therefore, higher T waves in the presenting electrocardiogram should represent earlier time to treatment and thus be associated with lower mortality following thrombolytic therapy. However, T-wave amplitude has never been evaluated as a prognostic marker in this setting. We examined clinical outcomes in 3,317 patients with acute myocardial infarction (AMI) who underwent thrombolysis in the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO-I) Study. Patients were classified as either those with high T waves or those with low T waves. Higher T waves were defined as those >98th percentile of the upper limit of normal. T-wave amplitude was also evaluated as a continuous variable according to infarct location (maximum T-wave amplitude) and as the amount of excess T-wave amplitude above normal (excess T-wave amplitude). Patients with higher T waves had lower 30-day mortality than those without (5.2% vs 8.6%, p = 0.001) and were less likely to develop congestive heart failure (15% vs 24%, p

The study sought to evaluate the clinical safety and effectiveness of the SYNERGY stent for the treatment of patients in China. Eligible patients with de novo native coronary artery lesions were randomized to receive the SYNERGY or PROMUS Element Plus stents in a 1:1 ratio. Angiographic and

At the end of last century, a High Intensity Focused Ultrasound (HIFU) tumor therapy system was successfully developed and manufactured in China, which has been already applied to clinical therapy. This article aims to discuss the HIFU therapy system and its application. Detailed research includes the following: power amplifiers for high‐power ultrasound, ultrasound transducers with large apertures, accurate 3‐D mechanical drives, a software control system (both high‐voltage control and low‐voltage control), and the B‐mode ultrasonic diagnostic equipment used for treatment monitoring. Research on the dosage of ultrasound required for tumour therapy in multiple human cases has made it possible to relate a dosage formula, presented in this paper, to other significant parameters such as the volume of thermal tumor solidification, the acoustic intensity (I), and the ultrasound emission time (tn). Moreover, the HIFU therapy system can be applied to the clinical treatment of both benign and malignant tumors in the pelvic and abdominal cavity, such as uterine fibroids, liver cancer and pancreatic carcinoma.

To evaluate the feasibility, safety and diagnostic accuracy of pharmacologic stress of (99m)Technetium-MIBI single-photon emission computed tomography (SPECT) with intravenous adenosine triphosphate (ATP) in patients with suspected coronary artery disease.The study group included 263 patients who were suspected of having coronary artery disease. All patients underwent (99m)Tc-MIBI myocardial perfusion imaging with ATP infusion (0.16 mg/kg body weight per min for 5 min). 20 mCi of (99m)Tc-MIBI were injected 3 minutes after the start of ATP infusion. Myocardial SPECT images were obtained 60 minutes later. Then, two days later, 20 mCi of (99m)Tc-MIBI were administered at rest and myocardial SPECT was repeated. 51 patients also underwent coronary angiography within two weeks for evaluation of sensitivity and specificity of ATP-myocardial perfusion imaging in detection of coronary artery disease. The occurrence of cardiac and non-cardiac adverse effects was carefully monitored during and after intravenous ATP infusion.The ATP infusion protocol was completed in all patients. Although 59% of the patients had various kinds of adverse effects, most of them were mild. No patient required aminophyline. The most severe adverse effect was second degree type II atria-ventricular block (4/263), but all events were transient. The sensitivity and specificity of ATP-myocardial perfusion imaging were 97% and 82%, respectively.It is shown that (99m)Technetium-MIBI SPECT with intravenous ATP is a safe and feasible technique for detecting coronary artery disease in patients unable to perform the exercise test.