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The development of connected and autonomous vehicle (CAV) technology has received increasing attention in recent years. Although car-following behavior in mixed traffic with CAVs and human-driven vehicles (HDVs) is a core component of microscopic traffic simulation, intelligent traffic systems, etc., the current study of car-following behavior in mixed traffic has some limitations. Furthermore, actual data do not support its applicability to the Chinese traffic environment. To address this gap, this paper designs and organizes a car-following experiment in mixed traffic in Beijing, extracts the trajectory data of CAVs and HDVs based on video recognition, and reconstructs the extracted trajectory data using the Lagrangian theory and Kalman filter theory to ensure the accuracy of the data. Based on this data set, this paper develops an extended car-following model. The model considers the cooperation between drivers by reformulating the prospect theory (PT). The root mean square percentage error (RMSPE) is selected to calibrate and validate the parameters of the proposed model, and the results show that there is significant heterogeneity between CAVs and HDVs in mixed traffic, and the proposed model captures this heterogeneity well. The model presented in this paper provides theoretical support for microscopic traffic simulation in mixed traffic., Author(s): Shenzhen Ding [1]; Xumei Chen (corresponding author) [1,2]; Zexin Fu [1]; Fei Peng [1] 1. Introduction Traffic congestion has been a hot issue for decades and will remain so [...]

Breast reconstruction is essential for improving the appearance of patients after cancer surgery. Traditional breast prostheses are not appropriate for those undergoing partial resections and cannot detect and treat locoregional recurrence. Personalized shape prostheses that can smartly sense tumor relapse and deliver therapeutics are needed. A 3D-printed prosthesis that contains a therapeutic hydrogel is developed. The hydrogel, which is fabricated by crosslinking the polyvinyl alcohol with N1-(4-boronobenzyl)-N3-(4-boronophenyl)-N1, N1, N3, N3-tetramethylpropane-1,3-diaminium, is responsive to reactive oxygen species (ROS) in the tumor microenvironment. Specifically, RSL3, a ferroptosis inducer that is loaded in hydrogels, can trigger tumor ferroptosis. Intriguingly, RSL3 encapsulated in the ROS-responsive hydrogel exerts antitumor effects by increasing the numbers of tumor-infiltrated CD4+ T cells, CD8+ T cells, and M1 macrophages while reducing the number of M2 macrophages. Therefore, this new prosthesis not only allows personalized shape reconstruction, but also detects and inhibits tumor recurrence. This combination of aesthetic appearance and therapeutic function can be very beneficial for breast cancer patients undergoing surgery., (© 2024 The Author(s). Advanced Science published by Wiley‐VCH GmbH.)