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"Der vorliegende Artikel diskutiert Teilergebnisse eines laufenden Dissertationsprojekts, das Bedeutungen in Zusammenhang mit Asyl und dem Asylverfahren aus Perspektive der AsylwerberInnen selbst verstehen will. Entlang intersubjektiver Konzeptionalisierungen biografischer Zeiten - d.h. Vergangenheit, Gegenwart und Zukunft - wird einerseits gezeigt, wie AsylwerberInnen mit Sinnangeboten der rechtlichen Praxis umgehen, und andererseits, auf welche Handlungsorientierungen und Identitätskonzepte dabei referenziert wird. Zu diskutieren, wie biografische Zeiten geformt werden und in welcher Beziehung diese zu rechtlichen und gesellschaftlichen Strukturen stehen, ermöglicht einen differenzierten Blick auf die Asylwirklichkeit in Österreich und fordert die Vorstellung von getriebenen, passiven und ohnmächtigen Flüchtlingen bzw. AsylwerberInnen heraus, ohne die wirkmächtigen strukturellen Zwänge zu vernachlässigen." (Autorenreferat) "The presented article discusses first of all results of an ongoing PhD-project, interested in understanding the meanings with regard to asylum and the asylum procedure from an asylum seekers' perspective. Focusing on intersubjective conceptualizations of biographical times - i.e., the past, the present and the future - it is shown: on the one hand, how asylum seekers deal with offered meanings of the legal practice; on the other, therein referred forms of action orientation as well as identity concepts are identified. To discuss the constitution of biographical times as well as their relation to legal and social structures allows for a differentiated perspective on asylum reality in Austria; notions of the pushed, passive and powerless refugee or asylum seeker are challenged without neglecting the powerful structural constraints." (author's abstract)

Lebenswelt Großes Walsertal(Institutfür sozialwissenschaftliche Regionalforschung Veröffentlichungen 7)

Grenzüberwindung im Dreiländereck. Wahrnehmungshorizonte und Mobilitätsverhalten der Bevölkerung in der Bodenseeregion(Institutfür sozialwissenschaftliche Regionalforschung Veröffentlichungen 5)

Context: CDKAL1 is a recently discovered susceptibility gene for type 2 diabetes. Objective: Our objective was to investigate the impact of rs7754840 of CDKAL1 on insulin secretion, insulin sensitivity, and risk of type 2 diabetes. Design and settings: Study 1 (the EUGENE2 study) was a cross-sectional study including subjects from five white populations in Europe (Denmark, Finland, Germany, Italy, and Sweden). Study 2 is an ongoing prospective study of Finnish men. Participants: In study 1, 846 nondiabetic offspring of type 2 diabetic patients (age 40 +/- 10 yr; body mass index 26.7 +/- 5.0 kg/m(2)) participated. In study 2, subjects included 3900 middle-aged men (533 type 2 diabetic and 3367 nondiabetic subjects). Interventions: INTERVENTIONS included iv glucose-tolerance test (IVGTT), oral glucose-tolerance test (OGTT), and euglycemic-hyperinsulinemic clamp in study 1 and OGTT in study 2. Main outcome measures: Parameters of insulin secretion, insulin resistance, and glucose tolerance status were assessed. Results: In study 1, carriers of the GC and CC genotypes of rs7754840 had 11 and 24% lower first-phase insulin release in an IVGTT compared with that in carriers of the GG genotype (P = 0.002). The C allele was also associated with higher glucose area under the curve in an OGTT (P = 0.016). In study 2, rs7754840 was significantly associated with type 2 diabetes (P = 0.022) and markers of impaired insulin release [insulinogenic index (IGI), P = 0.012] in 2405 men with normal glucose tolerance. Conclusions: rs7754840 of CDKAL1 was associated with markers of impaired insulin secretion in two independent studies. Furthermore, rs7754840 was associated with type 2 diabetes in Finnish men (study 2). Therefore, CDKAL1 is likely to increase the risk of type 2 diabetes by impairing insulin secretion.