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15 results on '"Frijters, Dinnus H.M."'

11. Het beloop van gedragsproblemen bij oudere verpleeghuispatiënten met dementie die worden behandeld met antipsychotica

Author

Kleijer, Bart C., Van Marum, Rob J., Egberts, A. C.G.Toine, Jansen, Paul A.F., Frijters, Dinnus H.M., Heerdink, E. R.Rob, Ribbe, Miel W., APH - Aging & Later Life, and General practice

Abstract

Background: Although antipsychotic treatment of behavioral problems in dementia is common, studies investigating the course of these symptoms in nursing homes are scarce. Our primary objective is therefore to describe the course of behavioral problems during antipsychotic treatment in a large sample of elderly nursing home patients with dementia. Methods: The course of behavioral problems during antipsychotic treatment was studied by comparing the characteristics of patients before, during and after antipsychotic treatment. The study was conducted using the VURAIDB, a database with over 40,000 assessments of over 10,000 nursing home residents in the Netherlands. We used the Challenging Behavior Profile (CBP) to measure an overall behavior score. Results: In total, 556 patients starting with antipsychotics were studied. Of these, 101 (18.2%) improved and 260 (46.8%) deteriorated at three months on the behavior score, compared with their scores before therapy (z = -7.955; p

Published
2010

15. Relationship between symptoms of depression and agitation in nursing home residents with dementia.

Author

Volicer, Ladislav, Frijters, Dinnus H.M., and Van der Steen, Jenny T.

Abstract

Objective The aim of this study is to analyze modifiable factors related to agitation of nursing home residents with dementia. Methods Relationship of agitation with three modifiable factors (depression, psychosis, and pain) was explored using longitudinal Minimum Data Set (MDS) information from 2032 residents of Dutch nursing homes. Presence of agitation and depression was ascertained using validated scales based on MDS information. Presence of psychosis and pain was ascertained from the individual MDS items. Results There was a significant correlation between MDS depression and agitation scores. Depression scores increased in residents whose agitation worsened and decreased in residents whose agitation improved. Psychosis scores (combination of delusions and hallucinations) also correlated with MDS depression scores, and psychosis scores increased in residents whose agitation worsened. Pain scores correlated with agitation scores, but the pain scores did not change with changes in agitation. Depression symptoms were present in 51% of residents, while psychotic symptoms were present only in 15% of residents, and two-thirds of these residents were also depressed. Conclusion These results indicate that depression may be the most common factor associated with agitation in nursing home residents with dementia. Copyright © 2011 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Published
2012
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