90 results on '"Freidl M"'
Search Results
2. Deterioration of the transcriptional, splicing and elongation machinery in brain of fetal Down Syndrome
- Author
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Freidl, M., Gulesserian, T., Lubec, G., Fountoulakis, M., Lubec, B., and Lubec, Gert, editor
- Published
- 2001
- Full Text
- View/download PDF
3. Psychopharmakotherapie der Essstörungen: Einsatz, Wirkung und Bedeutung der medikamentösen Behandlung
- Author
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Aigner, Martin, Ossege, M., Freidl, M., and Wancata, J.
- Published
- 2010
- Full Text
- View/download PDF
4. How psychiatric patients perceive the public's stereotype of mental illness
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Freidl, M., Lang, T., and Scherer, M.
- Published
- 2003
- Full Text
- View/download PDF
5. Cognitive Behavior Therapy (CBT) versus Psychoeducation (PE) in bipolar disorder: a randomized controlled study: RC7
- Author
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Lenz, G, Bergthaler, A, Breit-Gabauer, B, Demelbauer, S, Stampfer, I, Aigner, M, Freidl, M, Nosiska, D, Ossege, M, and Schaffer, M
- Published
- 2009
6. Spectrum of cognitive, behavioural and emotional problems in children and young adults with Down syndrome
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Nicham, R., primary, Weitzdörfer, R., additional, Hauser, E., additional, Freidl, M., additional, Schubert, M., additional, Wurst, E., additional, Lubec, G., additional, and Seidl, R., additional
- Published
- 2003
- Full Text
- View/download PDF
7. The decreasing risk of suicide over a 30-year period after a suicide attempt
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Katschnig, H., Bankier, B., Freidl, M., Hanika, H., Krautgartner, M., Scherer, M., and Sint, P. P.
- Published
- 2004
8. Global pattern of experienced and anticipated discrimination against people with schizophrenia: a cross-sectional survey
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Thornicroft, G, Brohan, E, Rose, D, Sartorius, N, Leese, M, Katschnig, H, Freidl, M, Van Audenhove, C, Scheerder, G, Hwong, A, Villares, C, de Almeida Pimentel, F, Janas Murier, V, Tosta, R, Jorge, Mr, Veshova, G, Petrova, G, Sotirov, V, Vassilev, S, Germanov, D, Milev, R, Tackaberry, L, Kalakoutas, Y, Tziongourou, M, Law, A, Church, R, Fisher, J, Willis, R, Kumar, A, Kassam, A, Schmid, G, Wahlbeck, K, Lillqvist, J, Tuohimäki, C, Roelandt, Jl, Giordana, Jy, Daumerie, N, Baumann, Ae, Zäske, H, Weber, J, Decker, P, Gaebel, W, Möller, Hj, Economou, M, Gramandani, C, Louki, E, Kolostoumpis, D, Spiliotis, D, Yotis, L, Harangozo, J, Thara, R, Buizza, C, Cicolini, A, Lasalvia, Antonio, Maggiolo, D, Ricci, A, Rossi, G, Tansella, Michele, Vittorielli, M, Germanavicius, A, Markovskaja, N, Pazikaite, V, Kok Yoon, C, Hayati Ali, N, van Weeghel, J, Plooy, A, Johannessen, Jo, Dybvig, S, Bielañska, A, Cechnicki, A, Kaszynski, H, Vargas Moniz, M, Filipe, L, Teodorescu, R, Barova, M, Svab, V, Strbad, M, Reneses, B, Carrasco, Jl, Lopez Ibor JJ, Rössler, W, Lauber, C, Latypov, A, Uçok, A, Aslantas, B, Warner, R., University of Zurich, and Thornicroft, G
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Adult ,Employment ,Male ,medicine.medical_specialty ,media_common.quotation_subject ,Psychological intervention ,Psychosocial Deprivation ,Stigma (botany) ,610 Medicine & health ,Human sexuality ,2700 General Medicine ,10056 Clinic for Clinical and Social Psychiatry Zurich West (former) ,Interpersonal relationship ,Quality of life (healthcare) ,Interview, Psychological ,medicine ,Humans ,Interpersonal Relations ,Psychiatry ,media_common ,business.industry ,Mental Disorders ,Self-esteem ,General Medicine ,Mental illness ,medicine.disease ,Mental health ,schizophrenia ,stigma ,mental health ,Cross-Sectional Studies ,Female ,business ,Prejudice - Abstract
Summary Background Many people with schizophrenia experience stigma caused by other people's knowledge, attitudes, and behaviour; this can lead to impoverishment, social marginalisation, and low quality of life. We aimed to describe the nature, direction, and severity of anticipated and experienced discrimination reported by people with schizophrenia. Methods We did a cross-sectional survey in 27 countries, in centres affiliated to the INDIGO Research Network, by use of face-to-face interviews with 732 participants with schizophrenia. Discrimination was measured with the newly validated discrimination and stigma scale (DISC), which produces three subscores: positive experienced discrimination; negative experienced discrimination; and anticipated discrimination. Findings Negative discrimination was experienced by 344 (47%) of 729 participants in making or keeping friends, by 315 (43%) of 728 from family members, by 209 (29%) of 724 in finding a job, 215 (29%) of 730 in keeping a job, and by 196 (27%) of 724 in intimate or sexual relationships. Positive experienced discrimination was rare. Anticipated discrimination affected 469 (64%) in applying for work, training, or education and 402 (55%) looking for a close relationship; 526 (72%) felt the need to conceal their diagnosis. Over a third of participants anticipated discrimination for job seeking and close personal relationships when no discrimination was experienced. Interpretation Rates of both anticipated and experienced discrimination are consistently high across countries among people with mental illness. Measures such as disability discrimination laws might, therefore, not be effective without interventions to improve self-esteem of people with mental illness. Funding South London and Maudsley NHS Foundation Trustees, UK Department of Health SHiFT programme, German Ministry of Education and Research.
- Published
- 2009
9. Anticipated discrimination among people with schizophrenia
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Uçok, A, Brohan, E, Rose, D, Sartorius, N, Leese, M, Yoon, Ck, Plooy, A, Ertekin, Ba, Milev, R, Thornicroft, G, Katschnig, H, Freidl, M, Van Audenhove, C, Scheerder, G, Hwong, A, Villares, C, Pimentel Fde, A, Murier, Vj, Tosta, R, Jorge, Mr, Veshova, G, Petrova, G, Sotirov, V, Vassilev, S, Germanov, D, Tackaberry, L, Kalakoutas, Y, Tziongourou, M, Law, A, Church, R, Fisher, J, Willis, R, Kumar, A, Kassam, A, Schmid, G, Wahlbeck, K, Lillqvist, J, Tuohimäki, C, Roelandt, Jl, Giordana, Jy, Daumerie, N, Baumann, Ae, Zäske, H, Weber, J, Decker, P, Gaebel, W, Möller, Hj, Economou, M, Gramandani, C, Louki, E, Kolostoumpis, D, Spiliotis, D, Yotis, L, Harangozo, J, Thara, R, Cicolini, A, Lasalvia, Antonio, Maggiolo, D, Ricci, A, Tansella, Michele, Rossi, G, Vittorielli, M, Buizza, C, Germanavicius, A, Markovskaja, N, Pazikaite, V, Ali, Nh, van Weeghel, J, Johannessen, Jo, Dybvig, S, Bielañska, A, Cechnicki, A, Kaszynski, H, Vargas Moniz, M, Filipe, L, Teodorescu, R, Barova, M, Svab, V, Strbad, M, Reneses, B, Carrasco, Jl, Lopez Ibor JJ, Rössler, W, Lauber, C, Latypov, A, and Warner, R.
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Adult ,Male ,Self Disclosure ,diagnosis ,Social Stigma ,Middle Aged ,Global Health ,Adult, Attitude to Health, Cross-Sectional Studies, Emotional Intelligence, Female, Humans, Interpersonal Relations, Interview ,Psychological, Male, Middle Aged, Prejudice, Schizophrenia ,diagnosis, Schizophrenic Psychology, Self Disclosure, Sickness Impact Profile, Social Stigma, Socioeconomic Factors, World Health ,Cross-Sectional Studies ,Socioeconomic Factors ,Sickness Impact Profile ,Interview, Psychological ,World Health ,Schizophrenia ,Humans ,Psychological ,Female ,Interpersonal Relations ,Schizophrenic Psychology ,Interview ,Attitude to Health ,Prejudice ,Emotional Intelligence - Abstract
The aim of this study was to evaluate the level of anticipated discrimination in people with schizophrenia (n = 732) from 27 countries in the International Study of Discrimination and Stigma Outcomes (INDIGO).Anticipated discrimination was assessed through four questions of Discrimination and Stigma Scale. Twenty-five individuals were identified at each site who were reasonably representative of all such treated cases within the local area.Sixty-four per cent of the participants reported that they had stopped themselves from applying for work, training or education because of anticipated discrimination. Seventy-two per cent of them reported that they felt the need to conceal their diagnosis. Expecting to be avoided by others who know about their diagnosis was highly associated with decisions to conceal their diagnosis. Those who concealed their diagnosis were younger and more educated. The participants who perceived discrimination by others were more likely to stop themselves from looking for a close relationship. Anticipated discrimination in finding and keeping work was more common in the absence than in the presence of experienced discrimination, and the similar findings applied to intimate relationships.This study shows that anticipated discrimination among people with schizophrenia is common, but is not necessarily associated with experienced discrimination.
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- 2012
10. Physical illness in mentally ill people as perceived by patients and staff members across 14 European countries: variation, causes, risk factors and prevention strategies
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Weiser, P., Lucas Carrasco, R., Berti, Loretta, Burton, A., Freidl, M., Marginean, R., and Kilian, R.
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physical illness ,prevention ,psychiatric patients ,psychosis ,risk factors - Published
- 2010
11. Spectrum of cognitive, behavioural and emotional problems in children and young adults with Down syndrome
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Nicham R, Weitzdörfer R, Hauser E, Freidl M, Schubert M, Wurst E, Gert Lubec, and Seidl R
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Adult ,Intelligence Tests ,Male ,Chi-Square Distribution ,Adolescent ,Age Factors ,Social Behavior Disorders ,Neuropsychological Tests ,Cohort Studies ,Cross-Sectional Studies ,Child, Preschool ,Humans ,Female ,Affective Symptoms ,Down Syndrome ,Child ,Cognition Disorders - Abstract
In comparison to most other groups with intellectual disability individuals with Down syndrome are at lower risk for significant psychopathology, although relative to their typically developing peers they have higher rates of behavioural and emotional problems. A total of 43 Down syndrome patients (21 females and 22 males), who ranged in age from 5.33 to 30.58 years, were examined for the presence of age-related changes in the spectrum of externalizing and internalizing problems. Intelligence tests included Hamburg-Wechsler-Intelligenz Test für Kinder III (HAWIK-III), Hamburg-Wechsler-Intelligenz Test für Erwachsene (HAWIE-R) and Kaufman-Assessment-Battery for Children, German Version (K-ABC). Behavioural and emotional problems were assessed by the the Strengths and Difficulties Questionnaire for Parents, German Version (SDQ) and the Clinical Assessment Scale for Child and Adolescent Psychopathology (CASCAP). IQ was significantly inversly related to the age of patients. Externalizing behaviours (dominant, opposing/refusing, impulsiveness, inattention and increased motor activity) were significantly higher in the 5-10 years old group, whereas internalizing behaviours (shy/insecure, low self confidence, decreased motor activity) where more prevalent in adolescents and adults (10-30 years). Possible relationships between this age-related changes and increased risks of later-onset psychopathology (depression and dementia) are discussed.
- Published
- 2004
12. Gender-specific aspects of mothers and fathers caring for a schizophrenia patient
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Wancata, J, primary, Freidl, M, additional, Friedrich, F, additional, Matschnig, T, additional, Unger, A, additional, Kucera, A, additional, Takacs, S, additional, and Cerny, G, additional
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- 2011
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13. Needs of fathers and mothers of schizophrenia patients
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Wancata, J., primary, Matschnig, T., additional, Freidl, M., additional, Unger, A., additional, and Friedrich, F., additional
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- 2011
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14. The reliability of a brief diagnostic interview, the trips, for the assessment of psychiatric disorders according to ICD-10 in primary care and non-psychiatric medical settings
- Author
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Berger, P., primary, Sibitz, I., additional, Freidl, M., additional, Topitz, A., additional, and Katschnig, H., additional
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- 2011
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15. Pain and depression in general hospital patients
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Sibitz, I., primary, Berger, P., additional, Freidl, M., additional, Topitz, A., additional, Krautgartner, M., additional, Spiegel, W., additional, and Katschnig, H., additional
- Published
- 2011
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16. Stigma perception and depression among patients suffering from chronic somatoform disorders
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Freidl, M., primary and Aigner, M., additional
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- 2011
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17. „Sms-the subjective mania scale“
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Freidl, M., primary, Friedrich, F., additional, Kaiser, G., additional, and Wancata, J., additional
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- 2011
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18. Die Erfassung des Bedarfs bei Demenzkranken mittels Camberwell Assessment of Need (CANE) for the Elderly
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Kaiser, G., primary, Unger, A., additional, Marquart, B., additional, Weiss, M., additional, Freidl, M., additional, and Wancata, J., additional
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- 2010
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19. Psychopharmakotherapie der Essstörungen
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Aigner, Martin, primary, Ossege, M., additional, Freidl, M., additional, and Wancata, J., additional
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- 2010
- Full Text
- View/download PDF
20. Fathers and Mothers of Patients with Schizophrenia
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Wancata, J., primary, Freidl, M., additional, Krautgartner, M., additional, Friedrich, F., additional, Matschnig, T., additional, Unger, A., additional, Strobl, R., additional, and Cerny, G., additional
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- 2009
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21. Disability in Schizophrenic Disorders
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Wancata, J., primary, Freidl, M., additional, Friedrich, F., additional, Matschnig, T., additional, Unger, A., additional, Stockinger, A., additional, and Dantendorfer, K., additional
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- 2009
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22. Der Bedarf der Angehörigen Schizophrenie-Kranker
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Unger, A., primary, Krautgartner, M., additional, Freidl, M., additional, Stelzig-Schöler, R., additional, Rittmannsberger, H., additional, Simhandl, Ch., additional, Grill, W., additional, Doby, D., additional, and Wancata, J., additional
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- 2008
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23. How depressive symptoms correlate with stigma perception of mental illness
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Freidl, M., primary, Piralic Spitzl, S., additional, and Aigner, M., additional
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- 2008
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24. Transition probability form attempted to completed suicide: A thirty year follow-up study
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Katschnig, H., primary and Freidl, M., additional
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- 2007
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25. The stigma of mental illness: Anticipation and attitudes among patients with epileptic, dissociative or somatoform pain disorder
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Freidl, M., primary, Spitzl, S. Piralic, additional, Prause, W., additional, Zimprich, F., additional, Lehner-Baumgartner, Eva, additional, Baumgartner, C., additional, and Aigner, M., additional
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- 2007
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26. Gender aspects of parents' needs of schizophrenia patients.
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Wancata J, Freidl M, Krautgartner M, Friedrich F, Matschnig T, Unger A, Gössler R, Frühwald S, Wancata, Johannes, Freidl, Marion, Krautgartner, Monika, Friedrich, Fabian, Matschnig, Teresa, Unger, Anne, Gössler, Ralf, and Frühwald, Stefan
- Abstract
Background: Most studies about the problems and needs of schizophrenia carers included only one care-giving relative, usually the patients' mothers.Methods: 101 mothers and fathers of the same patients suffering from schizophrenia were included into this study. Their needs were assessed by means of the "Carers' Needs Assessment for Schizophrenia".Results: Mothers reported significantly more often problems than fathers concerning stress due to earlier life events and burn-out. Mothers needed interventions such as individual psychoeducation or family counselling more than twice as often as fathers. Overall, mothers reported higher numbers of problems and needs for intervention than fathers. The number of mothers' problems was predicted by not living with a partner and by a shorter duration of the patients' illness. The number of mothers' needs was predicted by more psychiatric symptoms, not living with a partner and a shorter duration of the patients' illness. Among fathers we could not identify any predictors, neither for the number of problems nor for the number of needs.Conclusions: Fathers and mothers often report problems and frequently need professional support. Overall, mothers exhibited more problems and needs for interventions than fathers. The differences between mothers and fathers indicate the importance of considering the carer's gender in clinical work. [ABSTRACT FROM AUTHOR]- Published
- 2008
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27. S09-04 - Needs of fathers and mothers of schizophrenia patients
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Wancata, J., Matschnig, T., Freidl, M., Unger, A., and Friedrich, F.
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- 2011
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28. P02-288 - Pain and depression in general hospital patients
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Sibitz, I., Berger, P., Freidl, M., Topitz, A., Krautgartner, M., Spiegel, W., and Katschnig, H.
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- 2011
- Full Text
- View/download PDF
29. P02-271 - The reliability of a brief diagnostic interview, the trips, for the assessment of psychiatric disorders according to ICD-10 in primary care and non-psychiatric medical settings
- Author
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Berger, P., Sibitz, I., Freidl, M., Topitz, A., and Katschnig, H.
- Published
- 2011
- Full Text
- View/download PDF
30. P01-530 - Stigma perception and depression among patients suffering from chronic somatoform disorders
- Author
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Freidl, M. and Aigner, M.
- Published
- 2011
- Full Text
- View/download PDF
31. P01-207 - „Sms-the subjective mania scale“
- Author
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Freidl, M., Friedrich, F., Kaiser, G., and Wancata, J.
- Published
- 2011
- Full Text
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32. CS11-01 Disability in schizophrenic disorders
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Wancata, J., Freidl, M., Friedrich, F., Matschnig, T., Unger, A., Stockinger, A., and Dantendorfer, K.
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- 2009
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33. S09-02 Fathers and mothers of patients with schizophrenia
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Wancata, J., Freidl, M., Krautgartner, M., Friedrich, F., Matschnig, T., Unger, A., Strobl, R., and Cerny, G.
- Published
- 2009
- Full Text
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34. Deterioration of the transcriptional, splicing and elongation machinery in brain of fetal Down syndrome
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Freidl M, Gulesserian T, Gert Lubec, Fountoulakis M, and Lubec B
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Male ,Proteome ,Transcription, Genetic ,RNA Splicing ,Brain ,Gene Expression Regulation, Developmental ,Peptide Elongation Factor Tu ,Proto-Oncogene Proteins c-crk ,Fetus ,Peptide Elongation Factor 1 ,Peptide Elongation Factor 2 ,Protein Biosynthesis ,Proto-Oncogene Proteins ,Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ,Humans ,Electrophoresis, Gel, Two-Dimensional ,Female ,Down Syndrome - Abstract
Perturbation of brain development i.e. regulation of gene expression, differentiation, growth and migration in Down Syndrome (DS) has been reported to occur early in life pointing to impairment of the complex system of transcription and or translation and indeed, altered expression of transcription factors has been reported in adult DS brain. We therefore decided to compare the transcriptional and translational machinery in cortex of brains of controls and fetuses with Down syndrome in the second trimenon of gestation. We determined a series of transcription/translation factors by 2 D-electrophoresis followed by MALDI--identification and quantification with specific software. The protooncogene C-CRK, CRK-like protein, elongation factor 1-alpha 1, elongation factor 2, elongation factor tu and two out of four spots representing PTB-associated splicing factor PSF were significantly downregulated in brain of fetal DS fetuses as compared to controls. The finding of reduced transcription and translation factors may indicate deranged protein synthesis. The underlying cause for individual reduced transcription, splicing and translation factors may be explained by chromosomal imbalance or by posttranslational modifications as e.g. phosphorylation, known to be aberrant in DS. Reduced expression of transcription factors in fetal DS during early life may be responsible or reflecting impaired brain development and deficient wiring of the brain in DS.
35. European network for promoting the physical health of residents in psychiatric and social care facilities (HELPS): background, aims and methods
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Marginean Roxana, Lucas Ramona, Lech Katarzyna, Larsen Jens, Lai Taavi, Hjorth Peter, Henderson John, Halis Ulaş, Germanavicius Arunas, Genova Aneta, Friedrich Fabian, Freidl Marion, Dragomirecka Eva, Dernovsek Mojca, Burton Alexandra, Burti Lorenzo, Berti Loretta, Alptekin Köksal, Losert Carolin, Becker Thomas, Weiser Prisca, McDaid David, Mladenova Maya, Munk-Jørgensen Povl, Paziuc Alexandru, Paziuc Petronela, Priebe Stefan, Prot-Klinger Katarzyna, Wancata Johannes, and Kilian Reinhold
- Subjects
Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background People with mental disorders have a higher prevalence of physical illnesses and reduced life expectancy as compared with the general population. However, there is a lack of knowledge across Europe concerning interventions that aim at reducing somatic morbidity and excess mortality by promoting behaviour-based and/or environment-based interventions. Methods and design HELPS is an interdisciplinary European network that aims at (i) gathering relevant knowledge on physical illness in people with mental illness, (ii) identifying health promotion initiatives in European countries that meet country-specific needs, and (iii) at identifying best practice across Europe. Criteria for best practice will include evidence on the efficacy of physical health interventions and of their effectiveness in routine care, cost implications and feasibility for adaptation and implementation of interventions across different settings in Europe. HELPS will develop and implement a "physical health promotion toolkit". The toolkit will provide information to empower residents and staff to identify the most relevant risk factors in their specific context and to select the most appropriate action out of a range of defined health promoting interventions. The key methods are (a) stakeholder analysis, (b) international literature reviews, (c) Delphi rounds with experts from participating centres, and (d) focus groups with staff and residents of mental health care facilities. Meanwhile a multi-disciplinary network consisting of 15 European countries has been established and took up the work. As one main result of the project they expect that a widespread use of the HELPS toolkit could have a significant positive effect on the physical health status of residents of mental health and social care facilities, as well as to hold resonance for community dwelling people with mental health problems. Discussion A general strategy on health promotion for people with mental disorders must take into account behavioural, environmental and iatrogenic health risks. A European health promotion toolkit needs to consider heterogeneity of mental disorders, the multitude of physical health problems, health-relevant behaviour, health-related attitudes, health-relevant living conditions, and resource levels in mental health and social care facilities.
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- 2009
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36. The imaging features of tape suture: a contemporary surgical material.
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Kurra C, Wasserman P, Khoury A, and Freidl M
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- Humans, Suture Anchors, Suture Techniques, Gelatin, Pilot Projects, Gadolinium, Biomechanical Phenomena, Sutures, Cadaver, Arthroscopy methods, Rotator Cuff Injuries surgery
- Abstract
Objective: To offer an adjunctive imaging tool to MRI for evaluating tape suture related rotator cuff repairs., Materials and Methods: A two-part pilot study was performed to assess visibility of tape suture following imaging with various modalities. Institutional research ethics board approval was obtained prior to cadaveric studies. Two tape sutures, FiberTape® and TigerTape®, were evaluated in each experiment. The first experiment assessed the tape suture's presence in a gelatin mold following exposure to X-ray, ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) without contrast. The second experiment assessed tape suture's visibility in a cadaveric shoulder model following a standard of care, double-row, transosseous equivalent rotator cuff repair. The same imaging protocols and equipment were used for each part of the study with the addition of MR arthrography-tailored images on the cadaveric specimen. All images were assessed by a musculoskeletal trained radiologist., Results: The gelatin study demonstrated that the tape suture was visible via ultrasound only. X ray, CT, and MRI did not show tape suture material. In the ultrasound component of the cadaveric study, distinct echogenic textural detail of the tape suture was easily identified, compatible with the simulated rotator cuff repair. X ray and unenhanced CT did not show the tape suture material or the rotator cuff. MRI without intraarticular gadolinium contrast did not adequately image the suture tape; however, faint artifact in the repair region was visualized. MRI with intra-articular contrast did not show the tape suture material in detail; however, the intraarticular gadolinium did provide an advantageous background of high T1 signal that contrasted with the cuff/suture construct., Conclusion: Ultrasound proved to be an effective imaging modality to visualize tape suture in both the gelatin and cadaveric parts of the pilot study. Ultrasound may be a useful tool to evaluate post-operative tape suture-related repairs in patients that cannot obtain MRIs or when the MRI findings are equivocal., (© 2022. The Author(s), under exclusive licence to International Skeletal Society (ISS).)
- Published
- 2023
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37. Determinants of quality of life improvements in anxiety and depressive disorders-A longitudinal study of inpatient psychotherapy.
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Freidl M, Wegerer M, Litvan Z, König D, Alexandrowicz RW, Portela-Millinger F, and Gruber M
- Abstract
Background: Quality of life (QoL) is substantially impaired in patients with anxiety disorders (AD) and depressive disorders (DD) and improvements in symptom burden after psychotherapy are not always paralleled by similar improvements in QoL. So far, little is known about treatment outcome in terms of QoL and predictors of QoL improvements following inpatient psychotherapy with a focus on cognitive behavior therapy (CBT). The current study aimed at investigating the relationship between changes in symptoms and QoL across different life domains. Additionally, predictors of a positive treatment outcome were evaluated., Methods: 122 patients with AD and/or DD undergoing an 8-weeks inpatient CBT program completed self-report measures of psychopathological symptoms and QoL at pre- and post-treatment. Mixed effects models were used to investigate changes, a confirmatory factor analysis was applied to analyze the latent factor structure of the anxiety sensitivity index and binary logistic regression analyses were performed for predictors of QoL improvements., Results: Patients showed moderate to strong decreases in anxious and depressive symptoms and moderate to strong improvements in general QoL, particularly in the psychological and physical QoL subdomains. Changes in symptom burden correlated most strongly with psychological and physical QoL. In addition, poor QoL before treatment and low levels of specific anxiety sensitivity symptoms (items 1 and 5) significantly predicted improvement in QoL., Conclusion: Patients with poor QoL who are not as inhibited to openly express their anxious feelings particularly benefit from inpatient psychotherapy (individual and group) to improve their QoL. In contrast, our research suggests that patients who are too anxious to openly express their nervousness should receive additional social skills training, more focused treatment to build sufficient self-confidence to better engage in the treatment program., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Freidl, Wegerer, Litvan, König, Alexandrowicz, Portela-Millinger and Gruber.)
- Published
- 2022
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38. Posterior Humeral Avulsion of the Glenohumeral Ligament: A Rare and Nonspecific Injury.
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Patel R, Grozenski A, Bradburn M, Freidl M, and Coleman J
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- Adolescent, Arthroscopy, Conservative Treatment, Female, Humans, Magnetic Resonance Imaging, Rotator Cuff Injuries drug therapy, Rotator Cuff Injuries surgery, Shoulder Dislocation diagnostic imaging, Shoulder Dislocation surgery, Baseball injuries, Chronic Pain etiology, Rotator Cuff Injuries diagnosis, Shoulder Dislocation complications, Shoulder Pain etiology
- Published
- 2020
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39. Triceps Tendon Injuries.
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Casadei K, Kiel J, and Freidl M
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- Diagnosis, Differential, Elbow diagnostic imaging, Humans, Physical Examination, Tendon Injuries diagnostic imaging, Elbow physiopathology, Tendon Injuries physiopathology, Tendon Injuries therapy, Elbow Injuries
- Abstract
Triceps tendon injuries are an uncommon clinical entity poorly described in the literature. This review discusses the spectrum of pathology, effective diagnosis, nonsurgical treatment, surgical treatment, rehabilitation, and surgical complications of triceps tendon injuries. Management of triceps tendinopathies depends on the mechanism of injury and the patient's motor examination. Triceps tendinopathies and partial tendon tears with intact strength can be managed conservatively with rest, ice, immobilization, nonsteroidal anti-inflammatory drugs, and physical therapy. If conservative management fails for 6 months or there are strength deficits on examination, surgery should be considered. Based on the current evidence, there are no clear guidelines for "best" surgical approach. Although rare, the most significant surgical complication to be concerned about is rerupture. Rerupture rate is 4.62% among the articles we reviewed.
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- 2020
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40. Relapse of obsessive-compulsive disorder after cerebral venous sinus thrombosis: a case report.
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Velikić V, Wippel A, and Freidl M
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- Adolescent, Adult, Clomipramine therapeutic use, Female, Humans, Obsessive-Compulsive Disorder drug therapy, Recurrence, Sertraline therapeutic use, Obsessive-Compulsive Disorder complications, Sinus Thrombosis, Intracranial complications
- Abstract
Obsessive-compulsive disorder (OCD) is characterized by repetitive, persistent and unwanted thoughts and ritualistic, repetitive behaviors. The pathophysiology of OCD involves many distinct cortical and subcortical regions and it has been reported that OCD may occur as a consequence of traumatic brain injury, infections and tumors as well as cerebrovascular insult such as cerebral venous sinus thrombosis (CVST). We here describe the case of a 36-year-old woman who developed OCD at the age of 13 with almost complete remission of the symptoms after a 1 year-long treatment. Interestingly, after suffering CVST at the superior sagittal sinus at the age of 33, she experienced a relapse of OCD. The patient was successfully treated with Sertraline and Clomipramine. Previous studies revealed cases of OCD following different cerebrovascular accidents, i.e. predominantly arterial stroke. However, the present case is the first to describe OCD after venous thrombosis. Based on our clinical experience, the most effective treatment of OCD after CVST represents the combination of the selective serotonin reuptake inhibitor Sertraline and the tricyclic antidepressant Clomipramine.
- Published
- 2020
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41. Personality functioning in anxiety disorders.
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Doering S, Blüml V, Parth K, Feichtinger K, Gruber M, Aigner M, Rössler-Schülein H, Freidl M, and Wininger A
- Subjects
- Adult, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Middle Aged, Personality Tests, Anxiety Disorders psychology, Panic Disorder psychology, Personality, Personality Disorders diagnosis, Phobic Disorders psychology
- Abstract
Background: The Alternative DSM-5 Model for Personality Disorders as well as the upcoming IDC-11 have established a new focus on diagnosing personality disorders (PD): personality functioning. An impairment of self and interpersonal functioning in these models represents a general diagnostic criterion for a personality disorder. Little is known so far about the impairment of personality functioning in patients with other mental disorders than PD. This study aims to assess personality functioning in patients with anxiety disorders., Methods: Ninety-seven patients with the diagnosis of generalized anxiety disorder, panic disorder, or phobia, and 16 healthy control persons were diagnosed using the Structured Clinical Interview for DSM-IV (SCID-I and -II) and were assessed by means of the Structured Interview for Personality Organization (STIPO) to determine the level of personality functioning., Results: While all three patient groups showed significant impairment in personality functioning compared to the control group, no significant differences were observed between the different patient groups. In all three groups of anxiety disorders patients with comorbid PD showed significantly worse personality functioning than patients without. Patients without comorbid PD also yielded a significant impairment in their personality functioning when compared to the control group., Conclusions: Anxiety disorders are associated with a significant impairment in personality functioning, which is significantly increased by comorbid PD. There are no differences in terms of personality functioning between patients with different anxiety disorders.
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- 2018
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42. [Pain Symptoms as Predictors of Depressive or Anxiety Disorders in Patients with Physical Illness].
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Freidl M, Berger P, Topitz A, Katschnig H, Williams J, Zsuzsa L, and Sibitz I
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- Adult, Anxiety Disorders diagnosis, Comorbidity, Cross-Sectional Studies, Diagnosis, Differential, Female, Germany, Humans, Interview, Psychological, Male, Mass Screening, Middle Aged, Pain Measurement psychology, Somatoform Disorders diagnosis, Surveys and Questionnaires, Anxiety Disorders epidemiology, Anxiety Disorders psychology, Illness Behavior, Pain epidemiology, Pain psychology, Somatoform Disorders epidemiology, Somatoform Disorders psychology
- Abstract
Objective: The aim of this study was to investigate the frequency of pain symptoms reported by patients of non-psychiatric hospital departments and to explore their association with affective and anxiety disorders., Methods: Patients of non-psychiatric hospital departments (n = 290) reported pain symptoms by filling in a self-rating questionnaire. Psychiatric examinations were performed by psychiatrists using a structured diagnostic interview. The sum-scores of self-reported pain symptoms were tested for their screening accuracy for anxiety and depression., Results: Patients suffering from affective or anxiety disorders reported significantly more often three or more pain symptoms (63 % vs. 28 %). Using a cut-off value of ≥ 3 of self-reported pain symptoms yielded a sensitivity of 63.1 % and a specificity of 71.7 %., Conclusions: These findings highlight the relevance of a higher number of pain symptoms as a possible indicator for affective and anxiety disorders. The use of pain symptoms as pre-screening for depression and anxiety might be a useful tool, but needs further research before it can be recommended., (© Georg Thieme Verlag KG Stuttgart · New York.)
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- 2016
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43. Effects of Clinical Decision Topic on Patients' Involvement in and Satisfaction With Decisions and Their Subsequent Implementation.
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Freidl M, Pesola F, Konrad J, Puschner B, Kovacs AI, De Rosa C, Fiorillo A, Krogsgaard Bording M, Kawohl W, Rössler W, Nagy M, Munk-Jørgensen P, and Slade M
- Subjects
- Adolescent, Adult, Europe, Female, Humans, Logistic Models, Male, Middle Aged, Physician-Patient Relations, Young Adult, Clinical Decision-Making, Mental Disorders economics, Mental Disorders therapy, Patient Participation, Patient Satisfaction
- Abstract
Objective: Clinical decision making is an important aspect of mental health care. Predictors of how patients experience decision making and whether decisions are implemented are underresearched. This study investigated the relationship between decision topic and involvement in the decision, satisfaction with it, and its subsequent implementation from both staff and patient perspectives., Methods: As part of the Clinical Decision Making and Outcome in Routine Care for People With Severe Mental Illness study, patients (N=588) and their providers (N=213) were recruited from community-based mental health services in six European countries. Both completed bimonthly assessments for one year using the Clinical Decision Making in Routine Care Scale to assess the decision topic and implementation; both also completed the Clinical Decision Making Involvement and Satisfaction Scale., Results: Three categories of decision topics were determined: treatment (most frequently cited), social, and financial. The topic identified as most important remained stable over the follow-up. Patients were more likely to rate their involvement as active rather than passive for social decisions (odds ratio [OR]=5.7, p<.001) and financial decisions (OR=9.5, p<.001). They were more likely to report higher levels of satisfaction rather than lower levels for social decisions (OR=1.5, p=.01) and financial decisions (OR=1.7, p=.01). Social decisions were more likely to be partly implemented (OR=3.0, p<.001) or fully implemented (OR=1.7, p=.03) than not implemented., Conclusions: Patients reported poorer involvement, satisfaction, and implementation in regard to treatment-related decisions, compared with social and financial decisions. Clinicians may need to employ different interactional styles for different types of decisions to maximize satisfaction and decision implementation.
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- 2016
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44. [Depression Symptoms of Mothers and Fathers of Persons with Schizophrenia].
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Alexandrowicz RW, König D, Unger A, Klug G, Soulier N, Freidl M, and Friedrich F
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- Adult, Aged, Cross-Sectional Studies, Depressive Disorder epidemiology, Female, Home Nursing psychology, Humans, Male, Middle Aged, Risk Factors, Statistics as Topic, Surveys and Questionnaires, Young Adult, Caregivers psychology, Depressive Disorder diagnosis, Depressive Disorder psychology, Fathers psychology, Mothers psychology, Psychotic Disorders psychology, Psychotic Disorders therapy, Schizophrenia therapy, Schizophrenic Psychology
- Abstract
Objective: The purpose of the present study was to investigate if depression symptomatology of patients' parents is predicted by the symptoms of schizophrenia., Methods: 101 mothers and 101 fathers of the same patients suffering from schizophrenia were included into this study. Parents filled in the "Beck Depression Inventory". Patients were assessed by means of the "Positive and Negative Syndrome Scale". For statistical analyses a Multidimensional Random Coefficients Multinomial Logit Model was applied., Results: We found a significant positive association between negative symptoms and depression severity of fathers and mothers. Further, a significant positive association between positive symptoms and depression severity of fathers, but not of mothers was found., Conclusion: Our results show that depression of mothers and of fathers is associated with symptoms of schizophrenia even when controlling for potential predictors., (© Georg Thieme Verlag KG Stuttgart · New York.)
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- 2016
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45. Development and evaluation of an Individualized Outcome Measure (IOM) for randomized controlled trials in mental health.
- Author
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Pesola F, Williams J, Bird V, Freidl M, Le Boutillier C, Leamy M, Macpherson R, and Slade M
- Subjects
- Adolescent, Adult, Aged, Feasibility Studies, Female, Humans, Male, Mental Disorders therapy, Middle Aged, Surveys and Questionnaires, Time Factors, Young Adult, Mental Disorders diagnosis, Mental Health, Outcome Assessment, Health Care methods, Randomized Controlled Trials as Topic
- Abstract
Pre-defined, researcher-selected outcomes are routinely used as the clinical end-point in randomized controlled trials (RCTs); however, individualized approaches may be an effective way to assess outcome in mental health research. The present study describes the development and evaluation of the Individualized Outcome Measure (IOM), which is a patient-specific outcome measure to be used for RCTs of complex interventions. IOM was developed using a narrative review, expert consultation and piloting with mental health service users (n = 20). The final version of IOM comprises two components: Goal Attainment (GA) and Personalized Primary Outcome (PPO). For GA, patients identify one relevant goal at baseline and rate its attainment at follow-up. For PPO, patients choose an outcome domain related to their goal from a pre-defined list at baseline, and complete a standardized questionnaire assessing the chosen outcome domain at baseline and follow-up. A feasibility study indicated that IOM had adequate completion (89%) and acceptability (96%) rates in a clinical sample (n = 84). IOM was then evaluated in a RCT (ISRCTN02507940). GA and PPO components were associated with each other and with the trial primary outcome. The use of the PPO component of IOM as the primary outcome could be considered in future RCTs. Copyright © 2015 John Wiley & Sons, Ltd., (Copyright © 2015 John Wiley & Sons, Ltd.)
- Published
- 2015
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46. [Projections about the future number of dementia sufferers: increasing life expectancy not sufficiently considered?].
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Wancata J, Freidl M, Unger A, Jahn R, Soulier N, Fellinger M, and Daniel R
- Subjects
- Aged, Aged, 80 and over, Austria epidemiology, Humans, Population Dynamics, Prevalence, Dementia epidemiology, Life Expectancy trends
- Abstract
Background: Several authors pointed out that in the next decades dementia will affect a considerably increasing number of the elderly. The question was raised if life-expectancy was projected to conservative, resulting in revisions with higher life-expectancy and larger numbers of the oldest population. The present paper analyses the influence of such revisions on the future numbers of dementia sufferers in Austria., Subjects and Methods: For this purpose we used meta-analyses of epidemiological studies and the population projections for the period until 2050 of the Austrian Bureau of Statistics as well as of the United Nations Population Division of the year 2001 as well of the year 2005., Results: Using the extrapolations of the Austrian Bureau of Statistics of the year 1999 as well as of the United Nations Population Division of the year 2001, the number of dementia cases in Austria in the year 2050 will rise to about 233 thousands. According to the four years later performed extrapolations of the United Nations Population Division of the year 2005, dementia cases in Austria will raise to about 262 thousands in the year 2050., Conclusions: In the next decades, the number of persons suffering from dementia will rise considerably. Increasing life-expectancy will result in markedly higher numbers of persons with dementia than estimated from earlier population projections. Nevertheless, this is the first analysis of future dementia cases based on projections from two different dates, but using the same source. We must conclude that the dramatically increasing number of dementia cases requires comprehensive planning of the health and social care system.
- Published
- 2015
47. [Burden of mothers and fathers of persons with schizophrenia].
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Friedrich F, Gross R, Wrobel M, Klug G, Unger A, Fellinger M, Süßenbacher S, Freidl M, Saumer G, and Wancata J
- Subjects
- Aged, Austria, Female, Humans, Male, Middle Aged, Needs Assessment, Psychiatric Status Rating Scales, Surveys and Questionnaires, Caregivers psychology, Cost of Illness, Fathers psychology, Mothers psychology, Psychotic Disorders psychology, Psychotic Disorders therapy, Schizophrenia therapy, Schizophrenic Psychology
- Abstract
Objective: Most studies about the burden of schizophrenia carers included only one care-giving relative, usually the patients' mothers. The present study intended to analyse differences of the level of burden between mothers and fathers of the same patients., Methods: 101 mothers and 101 fathers of the same patients suffering from schizophrenia were included into this study. They were assessed by means of the "Involvement Evaluation Questionnaire" and the "Carers' Needs Assessment for Schizophrenia"., Results: Mothers showed significantly higher scores than fathers regarding the subscores "Tensions" and "Urging". Multiple linear regression analyses showed positive associations between the frequency of mothers' as well as fathers' unmet needs and dimensions of caregiver involvement., Conclusion: Unmet needs among mothers and fathers have negative effects on their burden. The differences between mothers and fathers indicate the importance of considering the carer's gender in clinical work., (© Georg Thieme Verlag KG Stuttgart · New York.)
- Published
- 2015
- Full Text
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48. [Comorbid somatic illnesses in psychiatric inpatients - an analysis of administrative data].
- Author
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Friedrich F, Litvan Z, and Freidl M
- Subjects
- Adolescent, Adult, Aged, Austria, Comorbidity, Cross-Sectional Studies, Data Collection statistics & numerical data, Female, Health Services Research statistics & numerical data, Humans, International Classification of Diseases classification, International Classification of Diseases statistics & numerical data, Length of Stay statistics & numerical data, Male, Mental Disorders diagnosis, Mental Disorders psychology, Middle Aged, Patient Admission statistics & numerical data, Psychophysiologic Disorders diagnosis, Psychophysiologic Disorders psychology, Somatoform Disorders diagnosis, Somatoform Disorders psychology, Young Adult, Hospitals, Psychiatric statistics & numerical data, Mental Disorders epidemiology, Psychophysiologic Disorders epidemiology, Somatoform Disorders epidemiology
- Abstract
Purpose: This study intended to analyze the prevalence of physical diagnoses at psychiatric inpatient hospital wards., Methods: For this purpose we used partially aggregated administrative data from routine diagnostic documentation of Austrian hospitals. All psychiatric and physical main and secondary diagnoses according to ICD-10 of all psychiatric inpatient units in Austria of the years 2007 were used., Results: Of 79,027 psychiatric hospital admissions 75,224 received a psychiatric and 3803 a somatic main diagnosis at discharge. Diseases of the vascular system (20 %) were the most frequent somatic diagnoses, followed by endocrine and metabolic diseases (16.4 %) and neurological diseases (14.4 %). Among patients suffering from schizophrenia, the most frequent physical diagnoses were endocrine and metabolic diseases. Among those with affective disorders, vascular diseases as well as endocrine and metabolic diseases were found most often., Conclusions: Physical diagnoses are very common among psychiatric inpatients. Mass screening and specialized prevention programs should be evaluated regarding their effectiveness for this population.
- Published
- 2015
- Full Text
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49. [Prevalence and recognition of depression among inpatients of non-psychiatric hospital departments].
- Author
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Topitz A, Benda N, Saumer G, Friedrich F, König D, Soulier N, and Freidl M
- Subjects
- Adolescent, Adult, Aged, Austria, Cross-Sectional Studies, Depressive Disorder psychology, Female, Health Planning, Hospitals, General statistics & numerical data, Humans, Male, Middle Aged, Young Adult, Cooperative Behavior, Depressive Disorder diagnosis, Depressive Disorder epidemiology, Hospital Departments statistics & numerical data, Inpatients psychology, Inpatients statistics & numerical data, Interdisciplinary Communication, Patient Care Team
- Abstract
Purpose: The purpose of this study is to compare the prevalence of depression among different types of hospital departments. Furthermore, it compares different methods for assessment of its recognition by non-psychiatric physicians., Methods: 993 inpatients of internal, surgical, gynecological and physical rehabilitation wards of community hospitals were interviewed by research psychiatrists using the Clinical Interview Schedule. Ward physicians were asked to fill in a short questionnaire in order to assess whether they could correctly identify patients with mental illnesses. In addition, routine discharge diagnoses were assessed., Results: Of the total sample, 13.3 % suffered from depression. Depression was most frequent on physical rehabilitation units (24.2 %), followed by surgical (9.8 %) and internal (9.5 %) wards. On gynecological wards, prevalence of depression was lowest (8.7 %). Of those suffering from depression, 45.7 % were identified as mentally ill by non-psychiatric ward physicians when using questionnaire data. Only 21.0 % of the depressed received a psychiatric discharge diagnosis, which equals less than half of those identified by questionnaire., Results: Of the total sample, 13.3 % of patients suffered from depression. Depression was most frequent in physical rehabilitation units (24.2 %), followed by surgical (9.8 %) and internal (9.5 %) wards. In gynecological wards, the prevalence of depression was the lowest (8.7 %). Of those suffering from depression, 45.7 % were identified as mentally ill by non-psychiatric ward physicians when using questionnaire data. Only 21.0 % of the depressed received a psychiatric discharge diagnosis, less than half of those identified by the questionnaire., Conclusions: Depression is very common among inpatients of physical hospital departments. Unfortunately, depression is frequently overlooked in everyday clinical work. Routine discharge diagnoses give only very limited information about how often ward physicians recognize mental disorders. Furthermore, hospital discharge diagnoses should not be used for planning mental health services.
- Published
- 2015
- Full Text
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50. Psychiatric illness and length of stay in general hospitals: do case finding methods matter?
- Author
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Freidl M, Benda N, and Friedrich F
- Subjects
- Adult, Aged, Anxiety Disorders epidemiology, Austria, Comorbidity, Depressive Disorder, Major epidemiology, Female, Hospital Departments statistics & numerical data, Humans, Male, Middle Aged, Psychophysiologic Disorders epidemiology, Somatoform Disorders epidemiology, Hospitals, General statistics & numerical data, Length of Stay statistics & numerical data, Mental Disorders epidemiology, Patient Admission statistics & numerical data
- Abstract
Objective: Several prior studies have investigated whether patients with "non-cognitive" mental disorders (i.e., organic disorders, substance abuse, delirium, and psychotic disorders excluded) have longer Length Of Stay (LOS) than mentally healthy individuals in nonpsychiatric hospital settings. These studies yielded contrasting results. The present paper aims to examine whether methods of psychiatric case finding can explain these differences., Methods: Using the Clinical Interview Schedule (CIS) and the General Health Questionnaire (GHQ), 462 in-patients of medical, surgical, gynecological, and rehabilitation departments were assessed for the presence of psychiatric disorders., Results: In multiple regression analysis, all CIS-cases together did not show an association with LOS. Of the diagnostic groups assessed by CIS only major depression showed a significantly prolonged LOS. Using the GHQ sum-score as a continuous variable, LOS was significantly increased while using the GHQ as a dichotomous variable did not show such an association. After removing those suffering from multiple psychiatric diagnoses (such as major depression co-morbid with organic mental illness), none of the case definitions showed a significant association with LOS., Conclusions: It seems that different case finding methods yield different results concerning the association of psychiatric disorders with LOS. When interpreting these results the small size of some subsamples must be taken into consideration.
- Published
- 2015
- Full Text
- View/download PDF
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