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1. The HEV Ventilator: at the interface between particle physics and biomedical engineering

Author

Jan Buytaert, Paula Collins, Adam Abed Abud, Phil Allport, Antonio Pazos Álvarez, Kazuyoshi Akiba, Oscar Augusto de Aguiar Francisco, Aurelio Bay, Florian Bernard, Sophie Baron, Claudia Bertella, Josef X. Brunner, Themis Bowcock, Martine Buytaert-De Jode, Wiktor Byczynski, Ricardo De Carvalho, Victor Coco, Ruth Collins, Nikola Dikic, Nicolas Dousse, Bruce Dowd, Kārlis Dreimanis, Raphael Dumps, Paolo Durante, Walid Fadel, Stephen Farry, Antonio Fernàndez Prieto, Arturo Fernàndez Tèllez, Gordon Flynn, Vinicius Franco Lima, Raymond Frei, Abraham Gallas Torreira, Tonatiuh García Chàvez, Evangelos Gazis, Roberto Guida, Karol Hennessy, Andre Henriques, David Hutchcroft, Stefan Ilic, Artūrs Ivanovs, Aleksandar Jevtic, Emigdio Jimenez Dominguez, Christian Joram, Kacper Kapusniak, Edgar Lemos Cid, Jana Lindner, Rolf Lindner, M. Ivàn Martínez Hernàndez, Mirko Meboldt, Marko Milovanovic, Sylvain Mico, Johan Morant, Michel Morel, Georg Männel, Dónal Murray, Irina Nasteva, Niko Neufeld, Igor Neuhold, Francisco Pardo-Sobrino López, Eliseo Pèrez Trigo, Gonzalo Pichel Jallas, Edyta Pilorz, Lise Piquilloud, Xavier Pons, David Reiner, Hector David Règules Medel, Saul Rodríguez Ramírez, Mario Rodíguez Cahuantzi, Carl Roosens, Philipp Rostalski, Freek Sanders, Eric Saucet, Marianne Schmid Daners, Burkhard Schmidt, Patrick Schoettker, Rainer Schwemmer, Heinrich Schindler, Archana Sharma, Derick Sivakumaran, Christophe Sigaud, Vasilios Spitas, Nicola Steffen, Peter Svihra, Guillermo Tejeda Muñoz, Nikolaos Tachatos, Efstratios Tsolakis, Jan van Leemput, Laurence Vignaux, Francois Vasey, Hamish Woonton, and Ken Wyllie

Subjects
COVID-19, ventilation modes, triggering, oxygen enrichment, Science
Abstract

A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. The HEV design is suitable for use both in and out of hospital intensive care units, provides a variety of modes and is capable of supporting spontaneous breathing and supplying oxygen-enriched air. An external air supply can be combined with the unit for use in situations where compressed air is not readily available. HEV supports remote training and post market surveillance via a Web interface and data logging to complement standard touch screen operation, making it suitable for a wide range of geographical deployment. The HEV design places emphasis on the ventilation performance, especially the quality and accuracy of the pressure curves, reactivity of the trigger, measurement of delivered volume and control of oxygen mixing, delivering a global performance which will be applicable to ventilator needs beyond the COVID-19 pandemic. This article describes the conceptual design and presents the prototype units together with a performance evaluation.

Published
2022
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2. Microchannel cooling for the LHCb VELO upgrade I

Author

Oscar Augusto de Aguiar Francisco, Wiktor Byczynski, Kazu Akiba, Claudia Bertella, Alexander Bitadze, Matthew Brock, Bartosz Bulat, Guillaume Button, Jan Buytaert, Stefano De Capua, Riccardo Callegari, Christine Castellana, Andrea Catinaccio, Catherine Charrier, Colette Charvet, Victor Coco, Paula Collins, Jordan Degrange, Raphael Dumps, Diego Alvarez Feito, Frank Fournel, Julian Freestone, Mariusz Jedrychowski, Vinicius Franco Lima, Abraham Gallas Torreira, Wouter Hulsbergen, Daniel Hynds, Gonzalo Arnau Izquierdo, Pawel Jalocha, Eddy Jans, Malcolm John, Nathan Jurik, Thomas Latham, Alexander Leflat, Edgar Lemos Cid, Rolf Lindner, Alessandro Mapelli, Abhijit Mathad, Andy Morris, Jerome Noel, Andrei Nomerotski, Rui de Oliveira, Martijn van Overbeek, Chris Parkes, Paolo Petagna, Alexandre Porret, Denis Renaud, Erno Roeland, Giulia Romagnoli, Eric Rouchouze, Krista de Roo, Freek Sanders, Thomas Schneider, Heinrich Schindler, Burkhard Schmidt, Andreas Schopper, Luke Scantlebury-Smead, Miranda Van Stenis, Peter Svihra, Benoit Teissandier, Jean-Francois Teissier, Xavier Thery, Eric Thomas, Bart Verlaat, and Mark R.J. Williams

Subjects
tubes, Nuclear and High Energy Physics, Physics - Instrumentation and Detectors, velo upgrade, model, FOS: Physical sciences, microchannel cooling, bi-phase co2, Instrumentation and Detectors (physics.ins-det), thermal figure of merit, High Energy Physics - Experiment, silicon wafer bonding, High Energy Physics - Experiment (hep-ex), prediction methods, heat, Detectors and Experimental Techniques, Instrumentation, Particle Physics - Experiment, QC, co2 evaporation
Abstract

The LHCb VELO Upgrade I, currently being installed for the 2022 start of LHC Run 3, uses silicon microchannel coolers with internally circulating bi-phase \cotwo for thermal control of hybrid pixel modules operating in vacuum. This is the largest scale application of this technology to date. Production of the microchannel coolers was completed in July 2019 and the assembly into cooling structures was completed in September 2021. This paper describes the R\&D path supporting the microchannel production and assembly and the motivation for the design choices. The microchannel coolers have excellent thermal peformance, low and uniform mass, no thermal expansion mismatch with the ASICs and are radiation hard. The fluidic and thermal performance is presented., 31 pages, 27 figures

Published
2022

3. The HEV Ventilator: at the interface between particle physics and biomedical engineering

Author

Jan Buytaert, Paula Collins, Adam Abed Abud, Phil Allport, Antonio Pazos Álvarez, Kazuyoshi Akiba, Oscar Augusto de Aguiar Francisco, Aurelio Bay, Florian Bernard, Sophie Baron, Claudia Bertella, Josef X. Brunner, Themis Bowcock, Martine Buytaert-De Jode, Wiktor Byczynski, Ricardo De Carvalho, Victor Coco, Ruth Collins, Nikola Dikic, Nicolas Dousse, Bruce Dowd, Kārlis Dreimanis, Raphael Dumps, Paolo Durante, Walid Fadel, Stephen Farry, Antonio Fernàndez Prieto, Arturo Fernàndez Tèllez, Gordon Flynn, Vinicius Franco Lima, Raymond Frei, Abraham Gallas Torreira, Tonatiuh García Chàvez, Evangelos Gazis, Roberto Guida, Karol Hennessy, Andre Henriques, David Hutchcroft, Stefan Ilic, Artūrs Ivanovs, Aleksandar Jevtic, Emigdio Jimenez Dominguez, Christian Joram, Kacper Kapusniak, Edgar Lemos Cid, Jana Lindner, Rolf Lindner, M. Ivàn Martínez Hernàndez, Mirko Meboldt, Marko Milovanovic, Sylvain Mico, Johan Morant, Michel Morel, Georg Männel, Dónal Murray, Irina Nasteva, Niko Neufeld, Igor Neuhold, Francisco Pardo-Sobrino López, Eliseo Pèrez Trigo, Gonzalo Pichel Jallas, Edyta Pilorz, Lise Piquilloud, Xavier Pons, David Reiner, Hector David Règules Medel, Saul Rodríguez Ramírez, Mario Rodíguez Cahuantzi, Carl Roosens, Philipp Rostalski, Freek Sanders, Eric Saucet, Marianne Schmid Daners, Burkhard Schmidt, Patrick Schoettker, Rainer Schwemmer, Heinrich Schindler, Archana Sharma, Derick Sivakumaran, Christophe Sigaud, Vasilios Spitas, Nicola Steffen, Peter Svihra, Guillermo Tejeda Muñoz, Nikolaos Tachatos, Efstratios Tsolakis, Jan van Leemput, Laurence Vignaux, Francois Vasey, Hamish Woonton, Ken Wyllie, and Publica

Subjects
Health Physics and Radiation Effects, triggering, Engineering, Multidisciplinary, biomedical engineering, COVID-19, ventilation modes, oxygen enrichment, medical physics
Abstract

A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. The HEV design is suitable for use both in and out of hospital intensive care units, provides a variety of modes and is capable of supporting spontaneous breathing and supplying oxygen-enriched air. An external air supply can be combined with the unit for use in situations where compressed air is not readily available. HEV supports remote training and post market surveillance via a Web interface and data logging to complement standard touch screen operation, making it suitable for a wide range of geographical deployment. The HEV design places emphasis on the ventilation performance, especially the quality and accuracy of the pressure curves, reactivity of the trigger, measurement of delivered volume and control of oxygen mixing, delivering a global performance which will be applicable to ventilator needs beyond the COVID-19 pandemic. This article describes the conceptual design and presents the prototype units together with a performance evaluation.

Published
2021

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