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This paper describes one possible origin point for fraudulent behavior within the American pharmaceutical industry. We argue that during the late nineteenth century therapeutic reformers sought to promote both laboratory science and increasingly systematized forms of clinical experiment as a new basis for therapeutic knowledge. This process was intertwined with a transformation in the ethical framework in which medical science took place, one in which monopoly status was replaced by clinical utility as the primary arbiter of pharmaceutical legitimacy. This new framework fundamentally altered the set of epistemic virtues-a phrase we draw from the philosophical field of virtue epistemology-considered necessary to conduct reliable scientific inquiry regarding drugs. In doing so, it also made possible new forms of fraud in which newly emergent epistemic virtues were violated. To make this argument, we focus on the efforts of Francis E. Stewart and George S. Davis of Parke, Davis & Company. Therapeutic reformers within the pharmaceutical industry, such as Stewart and Davis, were an important part of the broader normative and epistemic transformation we describe in that they sought to promote laboratory science and systematized clinical trials toward the twin goals of improving pharmaceutical science and promoting their own commercial interests. Yet, as we suggest, Parke, Davis & Company also serves as an example of a company that violated the very norms that Stewart and Davis helped introduce. We thus seek to describe one possible origin point for the widespread fraudulent practices that now characterize the pharmaceutical industry. We also seek to describe an origin point for why we conceptualize such practices as fraudulent in the first place.

Scientific misconduct (fabrication, falsification, and plagiarism) and detrimental research practices (selective reporting of data, inappropriate citation practice, ghostwriting) are admitted respectively by 2 % and 33 % of researchers. The consequences of scientific misconduct and detrimental research practices are disastrous, both for the doctors, who are the most affected researchers in view of the number of retracted articles, and for the patients, victims of false information that may have health consequences. In order to fight against the causes (promotion of doctors and allocation of resources to clinical wards and laboratories on purely quantitative research criteria, lack of training in scientific integrity in medical studies, heterogenous quality of reviewing, legal impunity), there are legislative, academic, technological and editorial solutions, but radical and urgent cultural change is needed first., (Copyright © 2020 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.)

Since the dawn of breast implantation back in the sixties, five generations of breast implants have tried to provide the most natural-looking results while striving to eliminate the risk of unpleasant ruptures or capsular contractures. National Health regulators (i.e. the FDA in USA and ANSM in France) have had an "after the facts" reaction, which led to a so-called "dirty war" among producers in the form of a 1992 Silicone's Moratorium (after suspicions of associated cancer or immune-related disorders) all this under the rigid oversight of a FDA director, who seemed more sensible to media scandal than scientific data. After more than a decade of consistent scientific evidence, the interdiction was finally ended in France in 2001 and in the USA in 2006, however the scandals resurfaced again in 2011 after a proven fraud on the "PIP - affair" and most recently with "breast implant associated - anaplastic large cell lymphoma", an extremely serious and rare pathology, treated only by surgical means, until further research. We describe also a chronology on the way the FDA finally recognized this dramatic complication., (Copyright © 2019 Elsevier Masson SAS. All rights reserved.)

The characterization of non-professional healers as "quacks" or "impostors" has influenced much of how such actors have been perceived by public opinion and in academic research. As a result of this, a divide has emerged between professional physicians, on the one hand, and those who acquired their knowledge in a traditional and non-academic way, on the other. This work questions the alleged divide between these two groups in the health field in order to offer a more complex and richer picture of local practices in Peru. Based mainly on correspondence from the Faculty of Medicine in Lima and newspaper ads, we reconstructed the attempts made by medical authorities to contain and exclude healers of Asian, European, or local backgrounds, many of which failed. For this reason, we studied two specific devices designed to legitimate and monitor physicians trained professionally: degrees or diplomas and lists of graduates, both of which are predecessors to our current identification cards and databases.

Introduction: The Olsen gang is a 14-episode film series about a gang of three thieves, who are very imaginative, but often unsuccessful in their burglary attempts "to score a real hit". In Denmark, the German Democratic Republic and Poland the films about Egon Olsen were blockbusters and still enjoy cult status there. Apart from a small amount of popular literature, the phenomenon of the Olsen gang has never been scientifically investigated from a forensic point of view so far., Methods: The films, produced between 1968 and 1998 (more than 22 hours of footage), were evaluated and compared with each other under forensic, legal and forensic-psychiatric aspects. The cooperation between the three scientific disciplines was intended to add a new perspective to the crime comedies., Results: A wide variety of medically relevant facts are presented in the movies. Even with all their criminal enthusiasm the Olsen gang commits almost no crimes against anyone's physical integrity. The films show legally comparable crimes, especially cases of severe band theft. Based on the criminal offenses committed, no gang member suffers from a psychiatric disorder fulfilling the criteria defined in Sections 20, 21 German Criminal Code., Conclusions: The great international success of the Olsen gang is certainly attributable to the imaginative theft plans for "fund-raising" and their almost pitiful failure. Many forensically relevant aspects are not shown in a realistic way. The accumulation of offenses and periods of imprisonment could result in preventive detention. The offenders are driven by normal psychological motives.

Fraudulent trading often deals with pharmacist, from several viewpoints. Pharmacist had often suffered from it, but he was also sometimes the source of falsification which initiated the need for inspection of pharmacy shops. The scientific knowledge of pharmacists, and particularly his analytical skills, explains their role to detect falsifications for products outside drugs, especially for food and also for drug use in competitive sport. Drug falsification goes back to time immemorial and goes on today very actively with Internet expansion. States and WHO try to fight against this plague with more and more complex tools such as Datamatrix progressively implemented worldwide. Pharmacy and falsifications, two words that will be unfortunately associated during the whole human history.

Background: The situation of the health-care services in the GDR during the 1980s has been reconstructed on the basis of the in part not previously released files of the Ministry for State Security (Stasi files)., Method: A research application was submitted to the responsible German Agency to examine the Stasi files on district physicians in the GDR. 78 extensive files were made available and evaluated according to the topics drugs and other medicinal aids, medical techniques, building status, procurement of foreign currencies, hygiene, Chernobyl, appeals and shortage of physicians., Results: The Stasi files reveal a dismal picture for the status of health-care services in the GDR during the 1980s. The authorities responsible for public health and the Ministry for State Security were well informed about the existing problems. Towards the end of the GDR the Ministry of Sate Security admitted internally that research and technology were lagging about 10 years behind that in Western countries., Conclusion: The discrepancy between the official reports and inofficial opinions was considerable. The Ministry of State Security worked mainly passively in an ideological fantasy world in which all such discrepencies had to be denied., (© Georg Thieme Verlag KG Stuttgart · New York.)

Adulterated and counterfeit drugs were pouring into the U.S. Providing poor medicines was a growing business, and the market was growing with the rapid expansion of the country itself. There seemed to be little that could be done to slow or stop it. The sophistication of the adulterations was superior to available tests, standards were lacking, and there were few trained pharmacists or physicians who could apply them. There were no laws that would prohibit the importation of these products nor limit their sale once ashore. This was the situation when a small group of New York pharmacists took it upon themselves to convince other health professionals and legislators that there was a problem and devised a solution that would establish patient safety as the core value of the emerging profession of pharmacy.

On the morning of November 7, 1938 vom Rath, a diplomat at the German embassy in Paris, was shot by Herschel Grynzspan, a Jewish teenager. Of the 5 shots fired, 2 hit vom Rath, one in the right shoulder and one in the abdomen. He was rushed to Alma Women's Hospital near the embassy, where emergency surgery was undertaken. Two days later his condition deteriorated rapidly and succumbed 55 hours after the shooting. It is believed that the assassination triggered the "Kristallnacht"--the organized Nazi pogrom against Jews across Germany. Based on the Alma hospital registry, autopsy findings and articles from recent years, the course of his condition and possible cause of his death are discussed. The possibility of malpractice, and even medical fraud, which led to his death are also mentioned.

In 1948 the New South Wales government instituted an inquiry into the claims of John Braund – a 78-year-old self-described ‘quack’ – that his secret treatment had cured 317 cancer sufferers. The ‘Braund controversy’, as it became known, was one of Australia’s most prominent cases of medical fraud. This paper examines that controversy and its effects on cancer philanthropy, medical research, and especially on legislation regulating treatment providers up to the present. With the Braund controversy in mind, the New South Wales (NSW) parliament struggled to develop legislation that would protect patients and punish quacks but also allow for serendipitous, unorthodox discoveries. Recent decades saw new elements added to this calculus – allowing a wide-ranging health marketplace, and allowing patients to choose their therapies. This paper argues that the particular body of law legislatures used in regulating cancer treatment and how regulations were framed reflected the changing context of healthcare and illustrates the calculus legislatures have undertaken in regulating the health marketplace, variously factoring in public safety, serendipitous discovery, the authority of orthodox medicine, patient choice, and economic opportunity.

This medical history essay claims that a medical fraud was committed by the authorities and was used as a pretext for the November 1938 anti-jewish Kristallnacht pogrom throughout the Third Reich. The suggested conspiracy covered up the real cause of death of the German Embassy's secretary in Paris. Baron Ernst vom Rath had been shot by a Jewish teenager who was frantic because of the plight of his family. A surgical analysis of the victim's injuries, and of the medical attention he received, suggests the likelihood of medical malpractice which led to his preventable demise.

One of the main obsessions of the early modern era was that of determining the notions of true and false, in order to apply them to various fields of knowledge and thus establish the divide between the lawful and unlawful. This trend was to have a particular impact on the fields of religion and science, where it became necessary to distinguish not only between true and false spirits, relics or miracles, but also between genuine and fake astrologers and alchemists. Situated in the middle ground between idealism and materialism, alchemy was prime territory for such tensions, as was demonstrated by a trial held in 1593 at the Jeronymite monastery of Santa Enracia in Saragossa, whose prior accused a friar of making "silver out of smoke and jewels from goblins".

This case study of the Australian Museum's Thylacine Cloning Project analyzes a frame dispute that emerged during public communication of a scientific project, which lasted from 1999 to 2005, and was premised on the idea of resurrecting an extinct species. In choosing the Tasmanian tiger--an iconic Australian marsupial officially declared extinct in 1986--the promoters of the cloning project ensured extensive media coverage. However, the popular and scientific attention generated by the idea of bringing back an extinct species challenged the Museum's efforts to frame the project in terms of scientific progress. The project repeatedly shifted from science to spectacle, as multiple stakeholders used the mass media to negotiate the scientific feasibility of trying to reverse extinction through the application of advanced biotechnology. The case study findings are relevant both to the emerging social issues surrounding the use of paleogenomics in wildlife conservation, and to the theoretical development of frame analysis as applied to scientific controversies.

Insider trading scandals on Wall Street have focused public attention on the abuse of money and power in the service of greed. The analytic situation described in this paper involves a patient who was involved in a major white-collar crime in the 1990s and imprisoned on charges of fraud. Release from prison brought his anxieties about money, work, and masculinity into sharp focus. The paper explores the some of the emotional conflicts and confusion around corporate success and failure, and the particular issues that arise when people identify themselves with the company they work for, something that corporate culture has always encouraged.

The BJN, even 100 years ago, published legal cases involving nurses or nursing situations. These were highlighted to illustrate the need for the State Registration of nurses. The following is a sample of some of the main points taken from such cases and helps us to compare some of our common professional issues with those of the past.

In early 1930s the newspapers and street journals in Europe and the United States were frequently reporting on a case of Zbigniew Dunikowski, a Polish engineer, who claimed to be in possession of a secret formula allowing production of gold from ordinary sand and rocks. He believed that most of those materials contain some particles of gold. For the precious metal however, it takes millions of years to precipitate into the ledges that could be mined. His method was based on a conviction, that the process can be accelerated. Although he was nicknamed "Polish alchemist" very soon, his vain promises attracted attention of financiers and even some European political leaders. After few years of futile experiments, he was sued by his impatient financial backers, and arrested. While in detention, he was allowed to make the last attempt to produce gold and regain his repute and freedom. When this attempt failed, the judge sentenced him for two years in prison and ordered him to repay some 3 million francs ($100,000) to his investors. He was also fined with ... 100 francs fine (some 4 dollars). It can not be definitively stated, whether Dunikowski was truly convicted that his formula for making gold could have been working or he acted as a swindler from the very beginning. He exclaimed that the accusation of fraud was caused by bankers, who would never let his method to undermine the status quo of world's economy. The experiments conducted in Ecole Centrale in Paris during his trial, were assisted buy several eminent French scientist. But although the judge sentenced, that Dunikowki's "secret process for turning sand into gold is an impracticable combination of absurdities and contradictions," Polish engineer was still able to find other backers after being released from French prison. We find the traces of his further activity in Italy, Switzerland, Belgium and Philippines. Finally, in early 1950s he ended his journey in the United States as a political refugee.

The past 100 years have seen a transition from a total ban in Britain on all advertising by doctors to the laity to almost total freedom of medical information, with probable benefit to public health but also a risk of loss of privacy. The Family Encyclopaedia of Medicine, written by Dr Hugh Howard Riddle and published by Lord Northcliffe's Daily Mail in 1914, started a flood of medical journalism in the press and the newer media. The lavishly advertised misattribution of its authorship to 'thirty eminent specialists', including Clifford Allbutt and William Osler, caused a major rumpus in the London Royal College of Physicians, but the fortnightly publication continued and became a four-volume book, popular with a public avid for more and more medical information.

When George Mossman, MD arrived in Bradford in 1787, he claimed to be a graduate of Edinburgh University and thus fully qualified to practise as a Physician. But after a few years it was revealed he had little medical education and had purchased his degree from St Andrews University. His career, however, apparently was unaffected by this and other revelations, and he went on to write several acclaimed essays and journal articles, and became Bradford's most popular and revered physician.

Dr John Maubray (1700-1732) was one of the most prominent man-midwives of Georgian London. His emphasis on the importance of physical examination and a combination of theoretical and practical teaching seems to have foreshadowed later methods of training in midwifery. His espousal of the non-instrumental Deventerian system of obstetrics and his activities in the parish of St George's, Hanover Square in London, identified him with the dominant Whig party. Although he failed to acquire a major patron, his network of social connections enabled him to obtain charitable and public service appointments, culminating in his chairmanship of the Charitable Corporation.

The history of the Piltdown hoax and its importance in convincing the world of Darwin's theory is reviewed. Compelling evidence existed from the beginning that the find was a hoax or, at the very least, was not evidence for human evolution. Yet for decades, Piltdown was touted by textbooks, articles, and major museums (including the American Museum of Natural History in New York) as major evidence of human evolution. The hoax is an excellent illustration of the difficulties in drawing conclusions about evolution from fossils. The hoax convinced many people of the validity of Darwinism, but its final, definitive exposure did little to alter the basic views of most Darwinists.

This essay proposes a new definition of scientific "misconduct," which is broader than the definition recently adopted by the U.S. government. According to the proposed definition, misconduct is a serious and intentional violation of accepted scientific practices, commonsense ethical norms, or research regulations in proposing, designing, conducting, reviewing, or reporting research. Punishable misconduct includes fabrication of data or experiments, falsification of data, plagiarism, or interference with a misconduct investigation. Misconduct does not include honest errors, differences of opinion, or ethically questionable research practices.