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18 results on '"Franke, Laura M."'

8. The relationship of neuroanatomy on resting motor threshold and induced electric field strength on treatment outcomes in mild to moderate traumatic brain injury patients during transcranial magnetic stimulation

Author

Lewis, Connor J., primary, Franke, Laura M., additional, Lee, Joseph V., additional, Mittal, Neil, additional, Gitchel, George T., additional, Perera, Robert A., additional, Holloway, Kathryn L., additional, Walker, William C., additional, Peterson, Carrie L., additional, and Hadimani, Ravi L., additional

Published
2023
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10. Supplemental_Figure_1 – Supplemental material for Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population

Author

Sheerin, Christina M., Franke, Laura M., Aggen, Steven H., Amstadter, Ananda B., and Walker, William C.

Subjects
FOS: Clinical medicine, Neuroscience, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, Supplemental_Figure_1 for Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population by Christina M. Sheerin, Laura M. Franke, Steven H. Aggen, Ananda B. Amstadter and William C. Walker in Clinical EEG and Neuroscience

Published
2018
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11. ClinEEG_SupplementalTables_revised – Supplemental material for Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population

Author

Sheerin, Christina M., Franke, Laura M., Aggen, Steven H., Amstadter, Ananda B., and Walker, William C.

Subjects
FOS: Clinical medicine, Neuroscience, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, ClinEEG_SupplementalTables_revised for Evaluating the Contribution of EEG Power Profiles to Characterize and Discriminate Posttraumatic Stress Symptom Factors in a Combat-Exposed Population by Christina M. Sheerin, Laura M. Franke, Steven H. Aggen, Ananda B. Amstadter and William C. Walker in Clinical EEG and Neuroscience

Published
2018
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12. Rapid-response impulsivity predicts depression and PTSD symptomatology at 1-year follow-up in blast-exposed service members

Author

Bjork, James M., Burroughs, Thomas K., Franke, Laura M., Pickett, Treven C., Johns, Sade E., Gerard Moeller, F., and Walker, William C.

Subjects
Adult, Male, Afghan Campaign 2001, Depression, Neuropsychological Tests, Article, United States, Stress Disorders, Post-Traumatic, Young Adult, Military Personnel, Blast Injuries, Brain Injuries, Traumatic, Impulsive Behavior, Humans, Female, Iraq War, 2003-2011, Biomarkers, Follow-Up Studies
Abstract

OBJECTIVE: To determine if elevated rapid-response impulsivity following blast exposure (as a putative marker of ventral prefrontal cortex (vPFC) damage) is predictive of future elevated affective symptomatology in blast-exposed service members. DESIGN: Longitudinal design with neurocognitive testing at initial assessment and one-year follow-up assessment of psychiatric symptomatology by telephone interview. SETTING: Veterans Administration medical centers and post-deployment assessment centers at military bases. PARTICIPANTS: Blast-exposed US military personnel (N=84) age 19–39. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Center for Epidemiological Studies-Depression Scale (CES-D) scores, post-traumatic stress disorder (PTSD) checklist (PCL-5) scores, and Alcohol Use Disorders Identification Test-C (AUDIT-C) scores at the 12-month follow-up telephone interview. RESULTS: After controlling for age and affective symptom scores reported at initial assessment, commission errors on the Continuous Performance Test-II of the initial assessment were predictive of higher symptom scores in CES-D and PCL-5 at follow-up, but were not predictive of AUDIT-C scores. CONCLUSION: Elevated rapid-response impulsivity, as a behavioral marker of reduced top-down frontocortical control, is a risk factor for elevated mood and PTSD symptoms over time in blast-exposed individuals. Future longitudinal studies with pre-deployment neurobehavioral testing could enable attribution of this relationship to blast-related vPFC damage.

Published
2017

16. Symptom Trajectories After Military Blast Exposure and the Influence of Mild Traumatic Brain Injury.

Author

Walker, William C., Franke, Laura M., Sima, Adam P., and Cifu, David X.

Abstract

Background: Blast-related mild traumatic brain injury (blast mTBI) is a signature wound of recent US military conflicts in the Middle East, but the relatedness of postconcussive symptoms (PCS) to the blast mTBI is unclear, and longitudinal symptom data are sparse. Objectives: To characterize post deployment symptom levels and trajectories and to determine relationship to blast mTBI. Methods: A total of 216 participants within 2 years of blast exposure during deployment underwent structured interviews or algorithmic questionnaires for blast mTBI. Detailed symptom inventories for PCS, pain, posttraumatic stress disorder, and depression were taken serially at enrollment, 6 months, and 12 months later. Repeated-measure analysis of variance models were built. Results: Up to 50% of participants had at least 1 high-grade blast mTBI (with posttraumatic amnesia), 31% had low-grade only, and 19% had neither. Within the entire cohort, all 4 composite symptom scores started high and stayed unchanged. Between blast mTBI groups, symptom scores differed at every time point with some evidence of convergence over time. The PCS groups, different by definition to start, diverged further over time with those initially more symptomatic becoming relatively more so. Conclusions: History of blast mTBI accompanied by posttraumatic amnesia is associated with greater nonspecific symptoms after deployment, and prognosis for improvement when symptoms are prominent is poor. [ABSTRACT FROM AUTHOR]

Published
2017
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