1. Enhancing adhesion and alignment of human gingival fibroblasts on dental implants
- Author
-
Aydin Gülses, Catharina Marques Sacramento, Ayman Haidar, Oral Cenk Aktas, Wolfgang Metzger, Yahya Açil, Frank P. Nothdurft, and Jörg Wiltfang
- Subjects
Dental Implants ,Titanium ,Surface Properties ,business.industry ,medicine.medical_treatment ,Laser treatment ,Gingiva ,Connective tissue ,030206 dentistry ,Fibroblasts ,Isotropic etching ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Cell Adhesion ,medicine ,Humans ,Surgery ,Oral Surgery ,Dental implant ,business ,Biomedical engineering - Abstract
Background Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture. Material and methods In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs). Results The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs. Conclusion Combining mechanical structuring with chemical etching enhanced both cellular attachment and the cellular alignment.
- Published
- 2019