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Cancer being a life treating ailment is the second reason of death universally. The growing threats of medication-resistant cancers indicates an crucial need for the improvement of more effective anticancer agents. Herbal medication offers very reasonable alternate to modern medicine against cancer. The investigation of natural products is a valued method for the detection and expansion of newer biologically dynamic compounds having exclusive assemblies and pathways. This work reviews certain medicinal plant with active phytochemicals, methodology of researches and their pharmacological characteristics. This work is created after careful literature review directed through relevant exploration of keywords in Clarivate Analytical, Web of Science, Scopus, Google Scholar, Science Direct, PubMed, MDPI, and Google Academic. This study was planned to accumulate the record of plants having anticancer activity and the evidences supporting their usage in cancer treatment. Fifty plants were selected based on their potenty as anticancer compounds. The thorough research studies exposed that plants and its phytochemicals can play a crucial role against oral, breast, lung, cervical, colon, stomach, hepatic cancers. The in vitro researches displayed that the plant secondary metabolites in extracts causes inhibition of cancer cell through DNA mutilation as well as stimulation of apoptosis-tempting enzymes in different models.

Acrocomia intumescens (“macaúba”) is a species that during processing generates a large amount of waste. The use of this residue for the production of flour for incorporation into food products is a way to minimize the cost and nutritionally enrich the final product. This work aimed to develop and analyze, in terms of physico-chemical and microbiological properties, cookies with macaúba almond cake residual flour. Sequilhos formulations were obtained using three different proportions of flour (2, 4 and 6%). The analysis of the flour allowed to find 4.29% of moisture, 1.13% of acidity, 5.33 of pH, 44.46% of carbohydrates, 28.74% of lipids, 20.06% of proteins and 2.45% of ash. In the analysis of the sequilhos formulations, the following values were found: moisture (5.03 to 8.13%), acidity (0.10 to 0.14%), pH (5.52 to 5.93), carbohydrates (67.17 to 73.37%), lipids (18.77 to 31.77%), proteins (0.85 to 1.92%), ash (0.83 to 0.94%) and total energy value (137.57 to 172,50 Kcal/100g). In microbiological analyzes it was highlighted that the sequilhos presented adequate sanitary conditions. The results indicate almond flour as an ingredient to be incorporated in the preparation of sequilhos, which in turn, presented satisfactory physico-chemical properties and microbiological results.

Commercialized mouthwashes are generally expensive for the most financially vulnerable populations. Thus, several studies evaluate the antimicrobial potential of herbal products, such as essential oils, to reduce the activity of microorganisms in the mouth. The objective of this research was to carry out the chemical characterization and antibacterial activity of the essential oil of Piper mosenii (EOPm), providing data that enable the development of a low-cost mouthwash formulation aimed at vulnerable communities. The analysis of the antibacterial potential and modulator of bacterial resistance was verified by the microdilution method to determine the minimum inhibitory concentration-MIC. The chemical components were characterized by gas chromatography coupled to mass spectrometry, where 23 chemical constituents were detected, with α-pinene, being the major compound. The EOPm showed a MIC ≥ 1024 µg/mL for all bacterial strains used in the tests. When the EOPm modulating activity was evaluated together with chlorhexidine, mouthwash and antibiotics against bacterial resistance, the oil showed a significant synergistic effect, reducing the MIC of the products tested in combination, in percentages between 20.6% to 96.3%. Therefore, it is recommended to expand the tests with greater variation of EOPm concentration and the products used in this research, in addition to the evaluation of toxicity and in vivo tests, seeking the development of a possible formulation of mouthwash accessible to the vulnerable population.

A anemia falciforme é uma doença causada por um distúrbio genético hereditário, devido a uma mutação do gene que codifica o aminoácido valina, passando a transcrever uma hemoglobina alterada. O objetivo do estudo é estabelecer os principais meios usados para o diagnóstico laboratorial da anemia falciforme e dos portadores destes traços, enfermidade esta que acomete todas as raças e gêneros, baseando-se em revisão bibliográfica atualizada por meio da pesquisa exploratória com abordagem qualitativa. Deste modo, pôde-se observar que, para definir tal quadro, existem inúmeros exames que auxiliam o clínico, desde exames simples, como o hemograma com a contagem da série vermelha, até exames mais sofisticados como resistência osmótica em solução de cloreto de sódio a 0,36%, eletroforese em pH alcalino em acetato de celulose, análise da morfologia eritrocitária, pesquisa de corpos de Heinz e agregados de hemoglobina H, entre outros. Os exames de triagem fornecem subsídios para o norteamento do pensamento clínico. Porém, são nos exames eletroforéticos que ocorre a confirmação diagnóstica. Logo, definimos nesse trabalho que o exame padrãoouro, para definição diagnóstica da anemia falciforme, continua sendo a eletroforese de hemoglobina.